The search for stable prognostic models in multiple imputed data sets.

abstract：BACKGROUND:Quantitative survey of research articles, as an application of bibliometrics, is an effective tool for grasping overall trends in various medical research fields. This type of survey has been also applied to infectious disease research; however, previous studies were insufficient as they underestimated artic...

journal_title：BMC medical research methodology

authors： Takahashi-Omoe H,Omoe K,Okabe N

更新日期：2009-10-06 00:00:00

abstract：BACKGROUND:Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death in Australia, and there are marked differences in mortality trends between men and women. In this study, we have sought to model and forecast age related changes in COPD mortality over time for men and women separately...

journal_title：BMC medical research methodology

authors： Erbas B,Ullah S,Hyndman RJ,Scollo M,Abramson M

更新日期：2012-02-21 00:00:00

abstract：BACKGROUND:Randomized controlled trials are the gold-standard for clinical trials. However, randomization is not always feasible. In this article we propose a prospective and adaptive matched case-control trial design assuming that a control group already exists. METHODS:We propose and discuss an interim analysis step...

journal_title：BMC medical research methodology

authors： Weber D,Uhlmann L,Schönenberger S,Kieser M

更新日期：2019-07-16 00:00:00

abstract：BACKGROUND:Retaining participants in cohort studies with multiple follow-up waves is difficult. Commonly, researchers are faced with the problem of missing data, which may introduce biased results as well as a loss of statistical power and precision. The STROBE guidelines von Elm et al. (Lancet, 370:1453-1457, 2007); V...

journal_title：BMC medical research methodology

authors： Karahalios A,Baglietto L,Carlin JB,English DR,Simpson JA

更新日期：2012-07-11 00:00:00

abstract：BACKGROUND:We developed and validated an automated database case definition for diabetes in children and youth to facilitate pharmacoepidemiologic investigations of medications and the risk of diabetes. METHODS:The present study was part of an in-progress retrospective cohort study of antipsychotics and diabetes in Te...

journal_title：BMC medical research methodology

authors： Bobo WV,Cooper WO,Stein CM,Olfson M,Mounsey J,Daugherty J,Ray WA

更新日期：2012-08-24 00:00:00

abstract：BACKGROUND:This article describes the design and baseline sample of a single-site trial comparing Individual Placement and Support (IPS) supported employment delivered within a Veterans Health Administration (VHA) primary care Patient Aligned Care Team (PACT) to treatment-as-usual vocational rehabilitation (TAU-VR) tha...

journal_title：BMC medical research methodology

authors： Davis LL,Blansett CM,Mumba MN,MacVicar D,Toscano R,Pilkinton P,Gay W,Bartolucci A

更新日期：2020-02-17 00:00:00

abstract：BACKGROUND:Observational outcome studies of patients with obstructive sleep apnea (OSA) require adjustment for co-morbidity to produce valid results. The aim of this study was to evaluate whether the combination of administrative data and self-reported data provided a more complete estimate of co-morbidity among patien...

journal_title：BMC medical research methodology

authors： Ronksley PE,Tsai WH,Quan H,Faris P,Hemmelgarn BR

更新日期：2009-07-15 00:00:00

abstract：BACKGROUND:Administrative databases offer vast amounts of data that provide opportunities for cost-effective insights. They simultaneously pose significant challenges to statistical analysis such as the redaction of data because of privacy policies and the provision of data that may not be at the level of detail requir...

journal_title：BMC medical research methodology

authors： Rosychuk RJ,Bachman JWN,Chen A,Hu XJ

更新日期：2020-12-07 00:00:00

abstract：BACKGROUND:Network meta-analysis can be used to combine results from several randomized trials involving more than two treatments. Potential inconsistency among different types of trial (designs) differing in the set of treatments tested is a major challenge, and application of procedures for detecting and locating inc...

journal_title：BMC medical research methodology

authors： Piepho HP

更新日期：2014-05-10 00:00:00

abstract：BACKGROUND:A strong need exists for a validated tool that clearly defines peer review report quality in biomedical research, as it will allow evaluating interventions aimed at improving the peer review process in well-performed trials. We aim to identify and describe existing tools for assessing the quality of peer rev...

journal_title：BMC medical research methodology

authors： Superchi C,González JA,Solà I,Cobo E,Hren D,Boutron I

更新日期：2019-03-06 00:00:00

abstract：BACKGROUND:In many studies the information of patients who are dying in the hospital is censored when examining the change in length of hospital stay (cLOS) due to hospital-acquired infections (HIs). While appropriate estimators of cLOS are available in literature, the existence of the bias due to censoring of deaths w...

journal_title：BMC medical research methodology

authors： Rahman S,von Cube M,Schumacher M,Wolkewitz M

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:The ethical, methodological, and technical aspects of pediatric research, often results in complications and delays in implementation. Our objective was to identify factors associated with the implementation duration of hospital-based pediatric studies. METHODS:All hospital-based pediatric studies sponsored...

journal_title：BMC medical research methodology

authors： Meier-Girard D,Tibi A,Abdoul H,Prot-Labarthe S,Brion F,Bourdon O,Alberti C

更新日期：2016-03-29 00:00:00

abstract：BACKGROUND:The systematic collection of high-quality mortality data is a prerequisite in designing relevant drowning prevention programmes. This descriptive study aimed to assess the quality (i.e., level of specificity) of cause-of-death reporting using ICD-10 drowning codes across 69 countries. METHODS:World Health O...

journal_title：BMC medical research methodology

authors： Lu TH,Lunetta P,Walker S

更新日期：2010-04-08 00:00:00

abstract：BACKGROUND:Outcomes collected in randomized clinical trials are observations of random variables that should be independent and identically distributed. However, in some trials, the patients are randomized more than once thus violating both of these assumptions. The probability of an event is not always the same when a...

journal_title：BMC medical research methodology

authors： Hozo I,Djulbegovic B,Clark O,Lyman GH

更新日期：2005-05-10 00:00:00

abstract：BACKGROUND:The Patient Reported Outcomes Measurement Information System 43-item short form (PROMIS-43) and the five-level EQ-5D (EQ-5D-5L) are recently developed measures of health-related quality of life (HRQL) that have potentially broad application in evaluating treatments and capturing burden of respiratory-related...

journal_title：BMC medical research methodology

authors： Lin FJ,Pickard AS,Krishnan JA,Joo MJ,Au DH,Carson SS,Gillespie S,Henderson AG,Lindenauer PK,McBurnie MA,Mularski RA,Naureckas ET,Vollmer WM,Lee TA,CONCERT Consortium.

更新日期：2014-06-16 00:00:00

abstract：BACKGROUND:Quantitative Microbial Risk Assessment (QMRA), a modelling approach, is used to assess health risks. Inputs into the QMRA process include data that characterise the intensity, frequency and duration of exposure to risk(s). Data gaps for water exposure assessment include the duration and frequency of urban no...

journal_title：BMC medical research methodology

authors： O'Toole JE,Sinclair MI,Leder K

更新日期：2009-11-09 00:00:00

abstract：BACKGROUND:Diabetes-related lower limb amputations are associated with considerable morbidity and mortality and are usually preceded by foot ulceration. The available systematic reviews of aggregate data are compromised because the primary studies report both adjusted and unadjusted estimates. As adjusted meta-analyses...

journal_title：BMC medical research methodology

authors： Crawford F,Anandan C,Chappell FM,Murray GD,Price JF,Sheikh A,Simpson CR,Maxwell M,Stansby GP,Young MJ,Abbott CA,Boulton AJ,Boyko EJ,Kastenbauer T,Leese GP,Monami M,Monteiro-Soares M,Rith-Najarian SJ,Veves A,Coates N

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:The reporting of randomised controlled trial (RCT) abstracts is of vital importance. The primary objective of this study was to investigate the association between structure format and RCT abstracts' quality of methodology reporting, informed by the current requirement and usage of structure formats by leadi...

journal_title：BMC medical research methodology

authors： Hua F,Walsh T,Glenny AM,Worthington H

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:The COVID-19 pandemic has evolved into one of the most impactful health crises in modern history, compelling researchers to explore innovative ways to efficiently collect public health data in a timely manner. Social media platforms have been explored as a research recruitment tool in other settings; however...

journal_title：BMC medical research methodology

authors： Ali SH,Foreman J,Capasso A,Jones AM,Tozan Y,DiClemente RJ

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:In clinical trials, study designs may focus on assessment of superiority, equivalence, or non-inferiority, of a new medicine or treatment as compared to a control. Typically, evidence in each of these paradigms is quantified with a variant of the null hypothesis significance test. A null hypothesis is assume...

journal_title：BMC medical research methodology

authors： van Ravenzwaaij D,Monden R,Tendeiro JN,Ioannidis JPA

更新日期：2019-03-29 00:00:00

abstract：BACKGROUND:For practical reasons it is not easy to obtain fasting samples in large population health surveys. Non-fasting triglyceride (Tg) values are difficult to interpret. The authors compared the accuracy of statistically corrected non-fasting Tg values with true fasting values and estimated the misclassification o...

journal_title：BMC medical research methodology

authors： Sundvall J,Leiviskä J,Laatikainen T,Peltonen M,Salomaa V,Vanhala M,Korpi-Hyövälti E,Lauronen J,Alfthan G

更新日期：2011-05-10 00:00:00

abstract：BACKGROUND:Studies in both paediatric and psychiatric settings often experience problems in recruitment. This can compromise the ability of the study to recruit to target, meaning studies are potentially underpowered. It can also result in a biased sample if a non-representative group are selectively recruited. Recruit...

journal_title：BMC medical research methodology

authors： Loades ME,Smith L,Higson-Sweeney N,Beasant L,Stallard P,Kessler D,Crawley E

更新日期：2019-04-27 00:00:00

abstract：BACKGROUND:Many medicines are dosed to achieve a particular therapeutic range, and monitored using therapeutic drug monitoring (TDM). The evidence base for a therapeutic range can be evaluated using systematic reviews, to ensure it continues to reflect current indications, doses, routes and formulations, as well as upd...

journal_title：BMC medical research methodology

authors： Cooney L,Loke YK,Golder S,Kirkham J,Jorgensen A,Sinha I,Hawcutt D

更新日期：2017-06-02 00:00:00

abstract：BACKGROUND:Biomarkers of exposures such as infection or environmental chemicals can be measured in small volumes of blood extracted from newborn dried blood spots (DBS) underscoring their potential utility for population-based research. However, few studies have evaluated the feasibility and utility of this resource; p...

journal_title：BMC medical research methodology

authors： Yeung EH,Louis GB,Lawrence D,Kannan K,McLain AC,Caggana M,Druschel C,Bell E

更新日期：2016-02-04 00:00:00

abstract：BACKGROUND:It is notoriously difficult to recruit patients to randomised controlled trials in primary care. This is particularly true when the disease process under investigation occurs relatively infrequently and must be investigated during a brief time window. Bell's palsy, an acute unilateral paralysis of the facial...

journal_title：BMC medical research methodology

authors： McKinstry B,Hammersley V,Daly F,Sullivan F

更新日期：2007-03-28 00:00:00

abstract：BACKGROUND:The aim was to describe a strategy for recruitment of healthy volunteers (HV) to a randomized trial that assessed the efficacy of different telephone techniques to assist HV in performing cardiac massage for vital emergency. Participation in the randomized trial was not financially compensated, however HV we...

journal_title：BMC medical research methodology

authors： Luzurier Q,Damm C,Lion F,Daniel C,Pellerin L,Tavolacci MP

更新日期：2015-01-05 00:00:00

abstract：BACKGROUND:How overall physical activity relates to specific activities and how reported activity changes over time may influence interpretation of observed associations between physical activity and health. We examine the relationships between various physical activities self-reported at different times in a large coh...

journal_title：BMC medical research methodology

authors： Armstrong ME,Cairns BJ,Green J,Reeves GK,Beral V,Million Women Study Collaborators.

更新日期：2011-06-22 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PRO) are important as endpoints in clinical trials and epidemiological studies. Guidelines for the development of PRO instruments and analysis of PRO data have emphasized the need to report methods used for sample size planning. The Raschpower procedure has been proposed for sample...

journal_title：BMC medical research methodology

authors： Blanchin M,Guilleux A,Perrot B,Bonnaud-Antignac A,Hardouin JB,Sébille V

更新日期：2015-03-15 00:00:00

abstract：:Clinical Decision Support Systems (CDSS) provide aid in clinical decision making and therefore need to take into consideration human, data interactions, and cognitive functions of clinical decision makers. The objective of this paper is to introduce a high level reference model that is intended to be used as a foundat...

journal_title：BMC medical research methodology

authors： Zikos D,DeLellis N

更新日期：2018-11-16 00:00:00

abstract：BACKGROUND:The effectiveness of multiple innovative recruitment strategies for enrolling Black/African American participants to the Adventist Health Study-2 (AHS-2) is described. The study's focus is diet and breast, prostate and colon cancer. METHODS:Promotions centered on trust, relationship building and incentives ...

journal_title：BMC medical research methodology

authors： Herring P,Butler T,Hall S,Bennett H,Montgomery SB,Fraser G

更新日期：2014-04-03 00:00:00