Positive predictive value of a case definition for diabetes mellitus using automated administrative health data in children and youth exposed to antipsychotic drugs or control medications: a Tennessee Medicaid study.

abstract：BACKGROUND:Available methods for the joint modelling of longitudinal and time-to-event outcomes have typically only allowed for a single longitudinal outcome and a solitary event time. In practice, clinical studies are likely to record multiple longitudinal outcomes. Incorporating all sources of data will improve the p...

journal_title：BMC medical research methodology

authors： Hickey GL,Philipson P,Jorgensen A,Kolamunnage-Dona R

更新日期：2016-09-07 00:00:00

abstract：BACKGROUND:Within cancer care, dynamic evaluations of the loss in expectation of life provides useful information to patients as well as physicians. The loss of lifetime function yields the conditional loss in expectation of life given survival up to a specific time point. Due to the inevitable censoring in time-to-eve...

journal_title：BMC medical research methodology

authors： Jakobsen LH,Andersson TM,Biccler JL,El-Galaly TC,Bøgsted M

更新日期：2019-01-28 00:00:00

abstract：BACKGROUND:Recruiting deaf and hard-of-hearing participants, particularly sign language-users, for genetics health service research is challenging due to communication barriers, mistrust toward genetics, and researchers' unfamiliarity with deaf people. Feelings of social exclusion and lack of social cohesion between re...

journal_title：BMC medical research methodology

authors： Kobayashi Y,Boudreault P,Hill K,Sinsheimer JS,Palmer CG

更新日期：2013-11-25 00:00:00

abstract：BACKGROUND:Multiple Imputation as usually implemented assumes that data are Missing At Random (MAR), meaning that the underlying missing data mechanism, given the observed data, is independent of the unobserved data. To explore the sensitivity of the inferences to departures from the MAR assumption, we applied the meth...

journal_title：BMC medical research methodology

authors： Héraud-Bousquet V,Larsen C,Carpenter J,Desenclos JC,Le Strat Y

更新日期：2012-06-08 00:00:00

abstract：BACKGROUND:The rationale for commissioning community pulmonary rehabilitation programmes is based on evidence from randomised clinical trials. However, there are a number of reasons why similar programmes might be less effective outside the environment of a clinical trial. These include a less highly selected patient g...

journal_title：BMC medical research methodology

authors： Goyder EC,Strong M,Green A,Holmes MW,Miles G,Reddington O,Lawson R,Lee A,Basran G

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:Systematic reviews often require substantial resources, partially due to the large number of records identified during searching. Although artificial intelligence may not be ready to fully replace human reviewers, it may accelerate and reduce the screening burden. Using DistillerSR (May 2020 release), we eva...

journal_title：BMC medical research methodology

authors： Hamel C,Kelly SE,Thavorn K,Rice DB,Wells GA,Hutton B

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:One of the main challenges for drug evaluation in rare diseases is the often heterogeneous course of these diseases. Traditional outcome measures may not be applicable for all patients, when they are in different stages of their disease. For instance, in Duchenne Muscular Dystrophy, the Six Minute Walk Test ...

journal_title：BMC medical research methodology

authors： Gaasterland CM,Jansen-van der Weide MC,Weinreich SS,van der Lee JH

更新日期：2016-08-17 00:00:00

abstract：BACKGROUND:The lack of suitable and reliable scales to measure self-reported health and health behaviour among people with intellectual disabilities (ID) is an important methodological challenge in health research. This study, which was undertaken together with co-researchers with ID, explores possibilities for self-re...

journal_title：BMC medical research methodology

authors： Vlot-van Anrooij K,Tobi H,Hilgenkamp TIM,Leusink GL,Naaldenberg J

更新日期：2018-07-16 00:00:00

abstract：BACKGROUND:It has been demonstrated that the enclosure of money with a mailed questionnaire increases the response rate significantly. We evaluated scratch lottery tickets as an alternative to cash. METHODS:1500 randomly selected Norwegians between the ages of 40 and 65 years were sent a short questionnaire. 250 recei...

journal_title：BMC medical research methodology

authors： Finsen V,Storeheier AH

更新日期：2006-04-28 00:00:00

abstract：BACKGROUND:Primary-care based randomized controlled trials (RCTs) build an important evidence base for general practice but little evidence exists about barriers to recruitment which often hamper such trials. We investigated the issues that impeded and facilitated recruitment to a clinical trial in general practice. M...

journal_title：BMC medical research methodology

authors： Foster JM,Sawyer SM,Smith L,Reddel HK,Usherwood T

更新日期：2015-03-12 00:00:00

abstract：BACKGROUND:Due to limited duration of follow up in clinical trials of cancer treatments, estimates of lifetime survival benefits are typically derived using statistical extrapolation methods. To justify the method used, a range of approaches have been proposed including statistical goodness-of-fit tests and comparing e...

journal_title：BMC medical research methodology

authors： Bullement A,Willis A,Amin A,Schlichting M,Hatswell AJ,Bharmal M

更新日期：2020-05-06 00:00:00

abstract：BACKGROUND:Posttraumatic growth is the positive change resulting from traumatic experiences and is typically assessed with retrospective measures like the Posttraumatic Growth Inventory (PTGI). The PTGI was designed to include reference to a specific traumatic event, making it difficult to implement, without change, in...

journal_title：BMC medical research methodology

authors： Kaur N,Porter B,LeardMann CA,Tobin LE,Lemus H,Luxton DD,Millennium Cohort Study Team.

更新日期：2017-04-20 00:00:00

abstract：BACKGROUND:Plasma cell dyscrasias (PCD) are a spectrum of disorders resulting from the clonal expansion of plasma cells, ranging from the pre-malignant condition monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM). MM generates a significant burden of disease on the community and it is pr...

journal_title：BMC medical research methodology

authors： Bergin K,Moore E,McQuilten Z,Wood E,Augustson B,Blacklock H,Ho J,Horvath N,King T,McNeil J,Mollee P,Quach H,Reid CM,Rosengarten B,Walker P,Spencer A

更新日期：2016-11-09 00:00:00

abstract：BACKGROUND:This study aimed to investigate whether awareness of being monitored by an accelerometer has an effect on physical activity in young people. METHODS:Eighty healthy participants aged 10-18 years were randomized between blinded and nonblinded groups. The blinded participants were informed that we were testing...

journal_title：BMC medical research methodology

authors： Vanhelst J,Béghin L,Drumez E,Coopman S,Gottrand F

更新日期：2017-07-11 00:00:00

abstract：BACKGROUND:Compliance is a critical issue for parental questionnaires in school based epidemiological surveys and high compliance is difficult to achieve. The objective of this study was to determine trends and factors associated with parental questionnaire compliance during respiratory health surveys of school childre...

journal_title：BMC medical research methodology

authors： Koshy G,Brabin BJ

更新日期：2012-04-20 00:00:00

abstract：BACKGROUND:The collection of individual-level pandemic (H1N1) 2009 influenza immunization data was considered important to facilitate optimal vaccine delivery and accurate assessment of vaccine coverage. These data are also critical for research aimed at evaluating the new vaccine's safety and effectiveness. Systems us...

journal_title：BMC medical research methodology

authors： Pereira JA,Quach S,Heidebrecht C,Foisy J,Quan S,Finkelstein M,Sikora CA,Bettinger JA,Buckeridge DL,McCarthy A,Deeks S,Kwong JC,Public Health Agency of Canada\/Canadian Institutes of Health Research Influenza Research Network Vacc

更新日期：2010-06-08 00:00:00

abstract：BACKGROUND:The Anglia Menorrhagia Education Study (AMES) is a randomized controlled trial testing the effectiveness of an education package applied to general practices. Binary data are available from two sources; general practitioner reported referrals to hospital, and referrals to hospital determined by independent a...

journal_title：BMC medical research methodology

authors： Nixon RM,Duffy SW,Fender GR

更新日期：2003-09-24 00:00:00

abstract：BACKGROUND:Cancer relapses may be useful to predict the risk of death. To take into account relapse information, the Landmark approach is popular. As an alternative, we propose the joint frailty model for a recurrent event and a terminal event to derive dynamic predictions of the risk of death. METHODS:The proposed pr...

journal_title：BMC medical research methodology

authors： Mauguen A,Rachet B,Mathoulin-Pélissier S,Lawrence GM,Siesling S,MacGrogan G,Laurent A,Rondeau V

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Navigating the world of qualitative thematic analysis can be challenging. This is compounded by the fact that detailed descriptions of methods are often omitted from qualitative discussions. While qualitative research methodologies are now mature, there often remains a lack of fine detail in their descriptio...

journal_title：BMC medical research methodology

authors： Roberts K,Dowell A,Nie JB

更新日期：2019-03-28 00:00:00

abstract：BACKGROUND:Randomised controlled trials (RCTs) are the gold standard for evidence-based practice. However, RCTs can have limitations. For example, translation of findings into practice can be limited by design features, such as inclusion criteria, not accurately reflecting clinical populations. In addition, it is expen...

journal_title：BMC medical research methodology

authors： Lemanska A,Byford RC,Cruickshank C,Dearnaley DP,Ferreira F,Griffin C,Hall E,Hinton W,de Lusignan S,Sherlock J,Faithfull S

更新日期：2020-07-25 00:00:00

abstract：BACKGROUND:The ethical, methodological, and technical aspects of pediatric research, often results in complications and delays in implementation. Our objective was to identify factors associated with the implementation duration of hospital-based pediatric studies. METHODS:All hospital-based pediatric studies sponsored...

journal_title：BMC medical research methodology

authors： Meier-Girard D,Tibi A,Abdoul H,Prot-Labarthe S,Brion F,Bourdon O,Alberti C

更新日期：2016-03-29 00:00:00

abstract：BACKGROUND:Systematic reviews (SRs) must be of high quality. The purpose of our research was to compare the methodological and reporting quality of original versus updated Cochrane SRs to determine whether updating had improved these two quality dimensions. METHODS:We identified updated Cochrane SRs published in issue...

journal_title：BMC medical research methodology

authors： Shea B,Boers M,Grimshaw JM,Hamel C,Bouter LM

更新日期：2006-06-13 00:00:00

abstract：BACKGROUND:The BSI-18 contains the three six-item scales somatization, depression, and anxiety as well as the Global Severity Index (GSI), including all 18 items. The BSI-18 is the latest and shortest of the multidimensional versions of the Symptom-Checklist 90-R, but its psychometric properties have not been sufficien...

journal_title：BMC medical research methodology

authors： Franke GH,Jaeger S,Glaesmer H,Barkmann C,Petrowski K,Braehler E

更新日期：2017-01-26 00:00:00

abstract：BACKGROUND:Studies examining incident heart failure (HF) have been limited to select populations. To examine incident HF with broader generalizability, there is need to assemble a HF-free cohort using a geographically-diverse sample. We aimed to develop and validate a simple medication-based strategy for assembling a H...

journal_title：BMC medical research methodology

authors： Goyal P,Mefford MT,Chen L,Sterling MR,Durant RW,Safford MM,Levitan EB

更新日期：2020-03-04 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PRO) are important as endpoints in clinical trials and epidemiological studies. Guidelines for the development of PRO instruments and analysis of PRO data have emphasized the need to report methods used for sample size planning. The Raschpower procedure has been proposed for sample...

journal_title：BMC medical research methodology

authors： Blanchin M,Guilleux A,Perrot B,Bonnaud-Antignac A,Hardouin JB,Sébille V

更新日期：2015-03-15 00:00:00

abstract：BACKGROUND:The aim was to describe a strategy for recruitment of healthy volunteers (HV) to a randomized trial that assessed the efficacy of different telephone techniques to assist HV in performing cardiac massage for vital emergency. Participation in the randomized trial was not financially compensated, however HV we...

journal_title：BMC medical research methodology

authors： Luzurier Q,Damm C,Lion F,Daniel C,Pellerin L,Tavolacci MP

更新日期：2015-01-05 00:00:00

abstract：BACKGROUND:Longitudinal studies using data collected as part of usual care risk providing biased results if visit times are related to the outcome of interest. Statistical methods for mitigating this bias are available but rarely used. This lack of use could be attributed to a lack of need or to a lack of awareness of ...

journal_title：BMC medical research methodology

authors： Farzanfar D,Abumuamar A,Kim J,Sirotich E,Wang Y,Pullenayegum E

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:Cross-cultural research with patient-reported outcomes measures (PROMs) assumes that the PROM in the target language will measure the same construct in the same way as the PROM in the source language. Yet translation methods are rarely used to qualitatively maximise construct equivalence or to describe the i...

journal_title：BMC medical research methodology

authors： Hawkins M,Cheng C,Elsworth GR,Osborne RH

更新日期：2020-05-26 00:00:00

abstract：BACKGROUND:Modern modelling techniques may potentially provide more accurate predictions of binary outcomes than classical techniques. We aimed to study the predictive performance of different modelling techniques in relation to the effective sample size ("data hungriness"). METHODS:We performed simulation studies bas...

journal_title：BMC medical research methodology

authors： van der Ploeg T,Austin PC,Steyerberg EW

更新日期：2014-12-22 00:00:00

abstract：BACKGROUND:Studies have shown that industry-sponsored meta-analyses of drugs lack scientific rigour and have biased conclusions. However, these studies have been restricted to certain medical specialities. We compared all industry-supported meta-analyses of drug-drug comparisons with those without industry support. ME...

journal_title：BMC medical research methodology

authors： Jørgensen AW,Maric KL,Tendal B,Faurschou A,Gøtzsche PC

更新日期：2008-09-09 00:00:00