Abstract:
BACKGROUND:This study aimed to investigate whether awareness of being monitored by an accelerometer has an effect on physical activity in young people. METHODS:Eighty healthy participants aged 10-18 years were randomized between blinded and nonblinded groups. The blinded participants were informed that we were testing the reliability of a new device for body posture assessment and these participants did not receive any information about physical activity. In contrast, the nonblinded participants were informed that the device was an accelerometer that assessed physical activity levels and patterns. The participants were instructed to wear the accelerometer for 4 consecutive days (2 school days and 2 school-free days). RESULTS:Missing data led to the exclusion of 2 participants assigned to the blinded group. When data from the blinded group were compared with these from the nonblinded group, no differences were found in the duration of any of the following items: (i) wearing the accelerometer, (ii) total physical activity, (iii) sedentary activity, and (iv) moderate-to-vigorous activity. CONCLUSIONS:Our study shows that the awareness of wearing an accelerometer has no influence on physical activity patterns in young people. This study improves the understanding of physical activity assessment and underlines the objectivity of this method. TRIAL REGISTRATION:NCT02844101 (retrospectively registered at July 13th 2016).
journal_name
BMC Med Res Methodoljournal_title
BMC medical research methodologyauthors
Vanhelst J,Béghin L,Drumez E,Coopman S,Gottrand Fdoi
10.1186/s12874-017-0378-5subject
Has Abstractpub_date
2017-07-11 00:00:00pages
99issue
1issn
1471-2288pii
10.1186/s12874-017-0378-5journal_volume
17pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Although a variety of instruments are available that capture stress experience, the assessment of chronic stress has been hindered by the lack of economical screening instruments. Recently, an English-language version of the Trier Inventory for Chronic Stress (TICS-EN) consisting of 57 items according to a s...
journal_title:BMC medical research methodology
pub_type: 杂志文章
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更新日期:2020-12-16 00:00:00
abstract:BACKGROUND:In recent months, multiple efforts have sought to characterize COVID-19 social distancing policy responses. These efforts have used various coding frameworks, but many have relied on coding methodologies that may not adequately describe the gradient in social distancing policies as states "re-open." METHODS...
journal_title:BMC medical research methodology
pub_type: 杂志文章
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更新日期:2020-12-08 00:00:00
abstract:BACKGROUND:The effectiveness of multiple innovative recruitment strategies for enrolling Black/African American participants to the Adventist Health Study-2 (AHS-2) is described. The study's focus is diet and breast, prostate and colon cancer. METHODS:Promotions centered on trust, relationship building and incentives ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-14-46
更新日期:2014-04-03 00:00:00
abstract:BACKGROUND:The longitudinal birth cohort study is the preferred design for studies of childhood health, particularly atopic disease. Still, prospective data collection depends on recollection of the medical history since the previous visit representing a potential recall-bias. We aimed to ascertain the quality of infor...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-160
更新日期:2012-10-22 00:00:00
abstract:BACKGROUND:Technical advances following the Human Genome Project revealed that high-quality and -quantity DNA may be obtained from whole saliva samples. However, usability of previously collected samples and the effects of environmental conditions on the samples during collection have not been assessed in detail. In fi...
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pub_type: 杂志文章
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更新日期:2011-12-19 00:00:00
abstract:BACKGROUND:Quantitative Microbial Risk Assessment (QMRA), a modelling approach, is used to assess health risks. Inputs into the QMRA process include data that characterise the intensity, frequency and duration of exposure to risk(s). Data gaps for water exposure assessment include the duration and frequency of urban no...
journal_title:BMC medical research methodology
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更新日期:2009-11-09 00:00:00
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更新日期:2020-06-26 00:00:00
abstract:BACKGROUND:Sleeping under a long-lasting insecticidal net (LLIN) is recommended for all pregnant women in sub-Saharan Africa, due to the high prevalence of malaria infection and its associated complications in the region. Despite this, LLIN use has still remained sub-optimal among pregnant women in Maiduguri, Nigeria. ...
journal_title:BMC medical research methodology
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更新日期:2019-07-18 00:00:00
abstract:BACKGROUND:Diagnostic problems in clinical trials are sometimes ordinal. For example, colon tumor staging was performed according to the TNM classification. However, clinical data are limited by markedly small sample sizes in some stage. METHODS:We propose a distribution-free test for detecting ordered alternatives in...
journal_title:BMC medical research methodology
pub_type: 杂志文章
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更新日期:2013-12-05 00:00:00
abstract:BACKGROUND:Models of hepatitis C virus (HCV) kinetics are increasingly used to estimate and to compare in vivo drug's antiviral effectiveness of new potent anti-HCV agents. Viral kinetic parameters can be estimated using non-linear mixed effect models (NLMEM). Here we aimed to evaluate the performance of this approach ...
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更新日期:2013-04-25 00:00:00
abstract:BACKGROUND:A recent paper found that terminal digits of statistical values in Nature deviated significantly from an equiprobable distribution, indicating errors or inconsistencies in rounding. This finding, as well as the discovery that a large percentage of p values were inconsistent with reported test statistics, led...
journal_title:BMC medical research methodology
pub_type: 评论,杂志文章
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更新日期:2006-09-13 00:00:00
abstract:BACKGROUND:Observational outcome studies of patients with obstructive sleep apnea (OSA) require adjustment for co-morbidity to produce valid results. The aim of this study was to evaluate whether the combination of administrative data and self-reported data provided a more complete estimate of co-morbidity among patien...
journal_title:BMC medical research methodology
pub_type: 杂志文章
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更新日期:2009-07-15 00:00:00
abstract:BACKGROUND:Primary-care based randomized controlled trials (RCTs) build an important evidence base for general practice but little evidence exists about barriers to recruitment which often hamper such trials. We investigated the issues that impeded and facilitated recruitment to a clinical trial in general practice. M...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-015-0012-3
更新日期:2015-03-12 00:00:00
abstract:BACKGROUND:A zero-inflated continuous outcome is characterized by occurrence of "excess" zeros that more than a single distribution can explain, with the positive observations forming a skewed distribution. Mixture models are employed for regression analysis of zero-inflated data. Moreover, for repeated measures zero-i...
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pub_type: 杂志文章
doi:10.1186/1471-2288-10-55
更新日期:2010-06-14 00:00:00
abstract:BACKGROUND:Although some nonparametric methods have been proposed in the literature to test for the equality of median survival times for censored data in medical research, in general they have inflated type I error rates, which make their use limited in practice, especially when the sample sizes are small. METHODS:In...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-016-0133-3
更新日期:2016-03-16 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-2288-15-2
更新日期:2015-01-05 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-2288-11-65
更新日期:2011-05-11 00:00:00
abstract:BACKGROUND:Many biological variables sampled from human subjects show a diurnal pattern, which poses special demands on the techniques used to analyze such data. Furthermore, most biological variables belong to nonlinear dynamical systems, which may make linear statistical techniques less suitable to analyze their dyna...
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pub_type: 杂志文章
doi:10.1186/s12874-018-0485-y
更新日期:2018-03-21 00:00:00
abstract:BACKGROUND:Greater transparency and, in particular, sharing of patient-level data for further scientific research is an increasingly important topic for the pharmaceutical industry and other organisations who sponsor and conduct clinical trials as well as generally in the interests of patients participating in studies....
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pub_type: 信件
doi:10.1186/s12874-016-0169-4
更新日期:2016-07-08 00:00:00
abstract:BACKGROUND:Crowding in the emergency department (ED) is associated with increased mortality, increased treatment cost, and reduced quality of care. Crowding arises when demand exceed resources in the ED and a first sign may be increasing waiting time. We aimed to quantify predictors for departure from the ED, and relat...
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pub_type: 杂志文章
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更新日期:2019-03-29 00:00:00
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更新日期:2012-09-24 00:00:00
abstract:BACKGROUND:Joint models of longitudinal and time-to-event data are increasingly used to perform individual dynamic prediction of a risk of event. However the difficulty to perform inference in nonlinear models and to calculate the distribution of individual parameters has long limited this approach to linear mixed-effe...
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-09-24 00:00:00
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pub_type: 杂志文章
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更新日期:2019-08-14 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2011-04-05 00:00:00
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journal_title:BMC medical research methodology
pub_type: 杂志文章
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更新日期:2005-02-07 00:00:00
abstract:BACKGROUND:Action research (AR) and randomized controlled trials (RCTs) are usually considered to be theoretically and practically incompatible. However, we argue that their respective strengths and weaknesses can be complementary. We illustrate our argument from a recent study assessing the effect of telemonitoring on...
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pub_type: 杂志文章,随机对照试验
doi:10.1186/s12874-016-0175-6
更新日期:2016-06-08 00:00:00
abstract:BACKGROUND:Greater transparency, including sharing of patient-level data for further research, is an increasingly important topic for organisations who sponsor, fund and conduct clinical trials. This is a major paradigm shift with the aim of maximising the value of patient-level data from clinical trials for the benefi...
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pub_type: 信件
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更新日期:2016-07-08 00:00:00
abstract:BACKGROUND:To describe how frequently harm is reported in the abstract of high impact factor medical journals. METHODS: DESIGN AND POPULATION:We carried out a blinded structured review of a random sample of 363 Randomised Controlled Trials (RCTs) carried out on human beings, and published in high impact factor medica...
journal_title:BMC medical research methodology
pub_type: 信件,评审
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更新日期:2008-03-27 00:00:00
abstract:BACKGROUND:Polypharmacy can be either beneficial or harmful to children. We conducted a scoping review to examine the concept of pediatric polypharmacy: its definition, prevalence, extent and gaps in research. In this manuscript, we report our transdisciplinary scoping review methodology. METHODS:After establishing a ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-018-0560-4
更新日期:2018-10-04 00:00:00