Eliciting parental support for the use of newborn blood spots for pediatric research.

abstract：BACKGROUND:Multiple imputation (MI) provides an effective approach to handle missing covariate data within prognostic modelling studies, as it can properly account for the missing data uncertainty. The multiply imputed datasets are each analysed using standard prognostic modelling techniques to obtain the estimates of ...

journal_title：BMC medical research methodology

authors： Marshall A,Altman DG,Holder RL,Royston P

更新日期：2009-07-28 00:00:00

abstract：BACKGROUND:Precise predictions of incidence and mortality rates due to breast cancer (BC) are required for planning of public health programs as well as for clinical services. A number of approaches has been established for prediction of mortality using stochastic models. The performance of these models intensely depen...

journal_title：BMC medical research methodology

authors： Mubarik S,Hu Y,Yu C

更新日期：2020-12-09 00:00:00

abstract：BACKGROUND:Studies have shown that industry-sponsored meta-analyses of drugs lack scientific rigour and have biased conclusions. However, these studies have been restricted to certain medical specialities. We compared all industry-supported meta-analyses of drug-drug comparisons with those without industry support. ME...

journal_title：BMC medical research methodology

authors： Jørgensen AW,Maric KL,Tendal B,Faurschou A,Gøtzsche PC

更新日期：2008-09-09 00:00:00

abstract：BACKGROUND:The self-controlled case series (SCCS) is a useful design for investigating associations between outcomes and transient exposures. The SCCS design controls for all fixed covariates, but effect modification can still occur. This can be evaluated by including interaction terms in the model which, when exponent...

journal_title：BMC medical research methodology

authors： Hawken S,Potter BK,Little J,Benchimol EI,Mahmud S,Ducharme R,Wilson K

更新日期：2016-09-23 00:00:00

abstract：BACKGROUND:Posttraumatic growth is the positive change resulting from traumatic experiences and is typically assessed with retrospective measures like the Posttraumatic Growth Inventory (PTGI). The PTGI was designed to include reference to a specific traumatic event, making it difficult to implement, without change, in...

journal_title：BMC medical research methodology

authors： Kaur N,Porter B,LeardMann CA,Tobin LE,Lemus H,Luxton DD,Millennium Cohort Study Team.

更新日期：2017-04-20 00:00:00

abstract：BACKGROUND:There is a recognised need to build primary care medication adherence services which are tailored to patients' needs. Continuous quality improvement of such services requires a regular working method of measuring adherence in order to monitor effectiveness. Self report has been considered the method of choic...

journal_title：BMC medical research methodology

authors： Garfield S,Clifford S,Eliasson L,Barber N,Willson A

更新日期：2011-11-03 00:00:00

abstract：BACKGROUND:Emergency Departments (EDs) are a first point-of-contact for many youth with mental health and suicidality concerns and can serve as an effective recruitment source for randomized controlled trials (RCTs) of mental health interventions. However, recruitment in acute care settings is impeded by several challe...

journal_title：BMC medical research methodology

authors： Tracey M,Finkelstein Y,Schachter R,Cleverley K,Monga S,Barwick M,Szatmari P,Moretti ME,Willan A,Henderson J,Korczak DJ

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:The main objective of this paper is to compare different methods for predicting the levels of SO2 air pollution in oil and gas producing area of rural western Canada. Month-long average air quality measurements were collected over a two-year period (2001-2002) at multiple locations, with some side-by-side me...

journal_title：BMC medical research methodology

authors： Burstyn I,Cherry NM,Yasui Y,Kim HM

更新日期：2008-07-04 00:00:00

abstract：BACKGROUND:Small group research in healthcare is important because it deals with interaction and decision-making processes that can help to identify and improve safer patient treatment and care. However, the number of studies is limited due to time- and resource-intensive data processing. The aim of this study was to e...

journal_title：BMC medical research methodology

authors： Aufegger L,Bicknell C,Soane E,Ashrafian H,Darzi A

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:Evidence syntheses, and in particular systematic reviews (SRs), have become one of the cornerstones of evidence-based health care. The Assessment of Multiple Systematic Reviews (AMSTAR) tool has become the most widely used tool for investigating the methodological quality of SRs and is currently undergoing r...

journal_title：BMC medical research methodology

authors： Wegewitz U,Weikert B,Fishta A,Jacobs A,Pieper D

更新日期：2016-08-26 00:00:00

abstract：BACKGROUND:Systematic reviews (SRs) must be of high quality. The purpose of our research was to compare the methodological and reporting quality of original versus updated Cochrane SRs to determine whether updating had improved these two quality dimensions. METHODS:We identified updated Cochrane SRs published in issue...

journal_title：BMC medical research methodology

authors： Shea B,Boers M,Grimshaw JM,Hamel C,Bouter LM

更新日期：2006-06-13 00:00:00

abstract：BACKGROUND:Quantitative Microbial Risk Assessment (QMRA), a modelling approach, is used to assess health risks. Inputs into the QMRA process include data that characterise the intensity, frequency and duration of exposure to risk(s). Data gaps for water exposure assessment include the duration and frequency of urban no...

journal_title：BMC medical research methodology

authors： O'Toole JE,Sinclair MI,Leder K

更新日期：2009-11-09 00:00:00

abstract：BACKGROUND:A frequently used statistic for testing homogeneity in a meta-analysis of K independent studies is Cochran's Q. For a standard test of homogeneity the Q statistic is referred to a chi-square distribution with K-1 degrees of freedom. For the situation in which the effects of the studies are logarithms of odds...

journal_title：BMC medical research methodology

authors： Kulinskaya E,Dollinger MB

更新日期：2015-06-10 00:00:00

abstract：BACKGROUND:The most commonly used survey methods are self-administered questionnaires, telephone interviews, and a mixture of both. But until now evidence out of randomised controlled trials as to whether patient responses differ depending on the survey mode is lacking. Therefore this study assessed whether patient res...

journal_title：BMC medical research methodology

authors： Lungenhausen M,Lange S,Maier C,Schaub C,Trampisch HJ,Endres HG

更新日期：2007-11-22 00:00:00

abstract：BACKGROUND:Few studies have compared methods to correct for retest effects or practice effects in settings where an acute event could influence test performance, such as major surgery. Our goal in this study was to evaluate the use of different methods to correct for the effects of practice or retest on repeated test a...

journal_title：BMC medical research methodology

authors： Racine AM,Gou Y,Fong TG,Marcantonio ER,Schmitt EM,Travison TG,Inouye SK,Jones RN

更新日期：2018-07-03 00:00:00

abstract：BACKGROUND:The rationale for commissioning community pulmonary rehabilitation programmes is based on evidence from randomised clinical trials. However, there are a number of reasons why similar programmes might be less effective outside the environment of a clinical trial. These include a less highly selected patient g...

journal_title：BMC medical research methodology

authors： Goyder EC,Strong M,Green A,Holmes MW,Miles G,Reddington O,Lawson R,Lee A,Basran G

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:Evidence suggests that differences exist in physical activity (PA) participation among Culturally and Linguistically Diverse (CALD) children and adolescents. It is possible that these differences could be influenced by variations in measurement technique and instrument reliability. However, culturally sensit...

journal_title：BMC medical research methodology

authors： Strugnell C,Renzaho A,Ridley K,Burns C

更新日期：2011-08-25 00:00:00

abstract：BACKGROUND:Sickness absence (SA) is an important social, economic and public health issue. Identifying and understanding the determinants, whether biological, regulatory or, health services-related, of variability in SA duration is essential for better management of SA. The conditional frailty model (CFM) is useful whe...

journal_title：BMC medical research methodology

authors： Torá-Rocamora I,Gimeno D,Delclos G,Benavides FG,Manzanera R,Jardí J,Alberti C,Yasui Y,Martínez JM

更新日期：2013-09-16 00:00:00

abstract：BACKGROUND:Syntheses of qualitative studies can inform health policy, services and our understanding of patient experience. Meta-ethnography is a systematic seven-phase interpretive qualitative synthesis approach well-suited to producing new theories and conceptual models. However, there are concerns about the quality ...

journal_title：BMC medical research methodology

authors： France EF,Ring N,Thomas R,Noyes J,Maxwell M,Jepson R

更新日期：2014-11-19 00:00:00

abstract：BACKGROUND:We would expect information on adverse drug reactions in randomised clinical trials to be easily retrievable from specific searches of electronic databases. However, complete retrieval of such information may not be straightforward, for two reasons. First, not all clinical drug trials provide data on the fre...

journal_title：BMC medical research methodology

authors： Derry S,Loke YK,Aronson JK

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:In many studies the information of patients who are dying in the hospital is censored when examining the change in length of hospital stay (cLOS) due to hospital-acquired infections (HIs). While appropriate estimators of cLOS are available in literature, the existence of the bias due to censoring of deaths w...

journal_title：BMC medical research methodology

authors： Rahman S,von Cube M,Schumacher M,Wolkewitz M

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:Standard random-effects meta-analysis methods perform poorly when applied to few studies only. Such settings however are commonly encountered in practice. It is unclear, whether or to what extent small-sample-size behaviour can be improved by more sophisticated modeling. METHODS:We consider likelihood-based...

journal_title：BMC medical research methodology

authors： Seide SE,Röver C,Friede T

更新日期：2019-01-11 00:00:00

abstract：BACKGROUND:Many medicines are dosed to achieve a particular therapeutic range, and monitored using therapeutic drug monitoring (TDM). The evidence base for a therapeutic range can be evaluated using systematic reviews, to ensure it continues to reflect current indications, doses, routes and formulations, as well as upd...

journal_title：BMC medical research methodology

authors： Cooney L,Loke YK,Golder S,Kirkham J,Jorgensen A,Sinha I,Hawcutt D

更新日期：2017-06-02 00:00:00

abstract：BACKGROUND:In clinical trials, study designs may focus on assessment of superiority, equivalence, or non-inferiority, of a new medicine or treatment as compared to a control. Typically, evidence in each of these paradigms is quantified with a variant of the null hypothesis significance test. A null hypothesis is assume...

journal_title：BMC medical research methodology

authors： van Ravenzwaaij D,Monden R,Tendeiro JN,Ioannidis JPA

更新日期：2019-03-29 00:00:00

abstract：BACKGROUND:Controlled clinical trials of health care interventions are either explanatory or pragmatic. Explanatory trials test whether an intervention is efficacious; that is, whether it can have a beneficial effect in an ideal situation. Pragmatic trials measure effectiveness; they measure the degree of beneficial ef...

journal_title：BMC medical research methodology

authors： Godwin M,Ruhland L,Casson I,MacDonald S,Delva D,Birtwhistle R,Lam M,Seguin R

更新日期：2003-12-22 00:00:00

abstract：BACKGROUND:In order to accurately measure and monitor levels of moderate-to-vigorous physical activity (MVPA) and sedentary behaviour (SB) in older adults, cost efficient and valid instruments are required. To date, the International Physical Activity Questionnaire (IPAQ) has not been validated with older adults (aged ...

journal_title：BMC medical research methodology

authors： Cleland C,Ferguson S,Ellis G,Hunter RF

更新日期：2018-12-22 00:00:00

abstract：BACKGROUND:It is widely recognised that the pursuit of sustainable development cannot be accomplished without addressing inequality, or observed differences between subgroups of a population. Monitoring health inequalities allows for the identification of health topics where major group differences exist, dimensions of...

journal_title：BMC medical research methodology

authors： Hosseinpoor AR,Nambiar D,Schlotheuber A,Reidpath D,Ross Z

更新日期：2016-10-19 00:00:00

abstract：BACKGROUND:To accurately predict the response to treatment, we need a stable and effective risk score that can be calculated from patient characteristics. When we evaluate such risks from time-to-event data with right-censoring, Cox's proportional hazards model is the most popular for estimating the linear risk score. ...

journal_title：BMC medical research methodology

authors： Omae K,Eguchi S

更新日期：2020-07-06 00:00:00

abstract：BACKGROUND:The Computer Adaptive Test version of the Community Reintegration of Injured Service Members measure (CRIS-CAT) consists of three scales measuring Extent of, Perceived Limitations in, and Satisfaction with community integration. The CRIS-CAT was developed using item response theory methods. The purposes of t...

journal_title：BMC medical research methodology

authors： Resnik L,Borgia M,Ni P,Pirraglia PA,Jette A

更新日期：2012-09-17 00:00:00

abstract：BACKGROUND:Mean arterial pressure (MAP), bispectral index (BIS), and minimum alveolar concentration (MAC) represent valuable, yet dynamic intraoperative monitoring variables. They provide information related to poor outcomes when considered together, however their collective behavior across time has not been characteri...

journal_title：BMC medical research methodology

authors： Schnetz MP,Hochheiser HS,Danks DJ,Landsittel DP,Vogt KM,Ibinson JW,Whitehurst SL,McDermott SP,Duque MG,Kaynar AM

更新日期：2019-01-14 00:00:00