Crowding in the emergency department in the absence of boarding - a transition regression model to predict departures and waiting time.

abstract：BACKGROUND:Due to limited duration of follow up in clinical trials of cancer treatments, estimates of lifetime survival benefits are typically derived using statistical extrapolation methods. To justify the method used, a range of approaches have been proposed including statistical goodness-of-fit tests and comparing e...

journal_title：BMC medical research methodology

authors： Bullement A,Willis A,Amin A,Schlichting M,Hatswell AJ,Bharmal M

更新日期：2020-05-06 00:00:00

abstract：BACKGROUND:Given an observed test statistic and its degrees of freedom, one may compute the observed P value with most statistical packages. It is unknown to what extent test statistics and P values are congruent in published medical papers. METHODS:We checked the congruence of statistical results reported in all the ...

journal_title：BMC medical research methodology

authors： García-Berthou E,Alcaraz C

更新日期：2004-05-28 00:00:00

abstract：BACKGROUND:Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a rare disease with extreme between-subject variability, especially with respect to rate of disease progression. This makes modelling a subject's disease progression, which is measured by the ALS Functional Rating Scale (ALSFRS), ver...

journal_title：BMC medical research methodology

authors： Karanevich AG,Statland JM,Gajewski BJ,He J

更新日期：2018-02-06 00:00:00

abstract：BACKGROUND:General Practitioners (GPs) respond poorly to postal surveys. Consequently there is potential for reduced data quality and bias in the findings. In general population surveys, response to postal questionnaires may be improved by reducing their length and offering incentives. The aim of this study was to inve...

journal_title：BMC medical research methodology

authors： Cottrell E,Roddy E,Rathod T,Thomas E,Porcheret M,Foster NE

更新日期：2015-01-06 00:00:00

abstract：BACKGROUND:Various papers have addressed pros and cons of the stepped wedge cluster randomized trial design (SWD). However, some issues have not or only limitedly been addressed. Our aim was to provide a comprehensive overview of all merits and limitations of the SWD to assist researchers, reviewers and medical ethics ...

journal_title：BMC medical research methodology

authors： de Hoop E,van der Tweel I,van der Graaf R,Moons KG,van Delden JJ,Reitsma JB,Koffijberg H

更新日期：2015-10-30 00:00:00

abstract：BACKGROUND:Social-environmental data obtained from the US Census is an important resource for understanding health disparities, but rarely is the full dataset utilized for analysis. A barrier to incorporating the full data is a lack of solid recommendations for variable selection, with researchers often hand-selecting ...

journal_title：BMC medical research methodology

authors： Handorf E,Yin Y,Slifker M,Lynch S

更新日期：2020-12-10 00:00:00

abstract：BACKGROUND:The collection of individual-level pandemic (H1N1) 2009 influenza immunization data was considered important to facilitate optimal vaccine delivery and accurate assessment of vaccine coverage. These data are also critical for research aimed at evaluating the new vaccine's safety and effectiveness. Systems us...

journal_title：BMC medical research methodology

authors： Pereira JA,Quach S,Heidebrecht C,Foisy J,Quan S,Finkelstein M,Sikora CA,Bettinger JA,Buckeridge DL,McCarthy A,Deeks S,Kwong JC,Public Health Agency of Canada\/Canadian Institutes of Health Research Influenza Research Network Vacc

更新日期：2010-06-08 00:00:00

abstract：BACKGROUND:Quantitative survey of research articles, as an application of bibliometrics, is an effective tool for grasping overall trends in various medical research fields. This type of survey has been also applied to infectious disease research; however, previous studies were insufficient as they underestimated artic...

journal_title：BMC medical research methodology

authors： Takahashi-Omoe H,Omoe K,Okabe N

更新日期：2009-10-06 00:00:00

abstract：BACKGROUND:Longitudinal studies using data collected as part of usual care risk providing biased results if visit times are related to the outcome of interest. Statistical methods for mitigating this bias are available but rarely used. This lack of use could be attributed to a lack of need or to a lack of awareness of ...

journal_title：BMC medical research methodology

authors： Farzanfar D,Abumuamar A,Kim J,Sirotich E,Wang Y,Pullenayegum E

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:This research aims to explore an identified gap in implementation science methodology, that is, how to assess context in implementation research. Context is among the strongest influences on implementation success but is a construct that is poorly understood and reported within the literature. Consequently, ...

journal_title：BMC medical research methodology

authors： Rogers L,De Brún A,McAuliffe E

更新日期：2020-06-15 00:00:00

abstract：BACKGROUND:The effectiveness of multiple innovative recruitment strategies for enrolling Black/African American participants to the Adventist Health Study-2 (AHS-2) is described. The study's focus is diet and breast, prostate and colon cancer. METHODS:Promotions centered on trust, relationship building and incentives ...

journal_title：BMC medical research methodology

authors： Herring P,Butler T,Hall S,Bennett H,Montgomery SB,Fraser G

更新日期：2014-04-03 00:00:00

abstract：BACKGROUND:Recruiting deaf and hard-of-hearing participants, particularly sign language-users, for genetics health service research is challenging due to communication barriers, mistrust toward genetics, and researchers' unfamiliarity with deaf people. Feelings of social exclusion and lack of social cohesion between re...

journal_title：BMC medical research methodology

authors： Kobayashi Y,Boudreault P,Hill K,Sinsheimer JS,Palmer CG

更新日期：2013-11-25 00:00:00

abstract：BACKGROUND:Greater transparency, including sharing of patient-level data for further research, is an increasingly important topic for organisations who sponsor, fund and conduct clinical trials. This is a major paradigm shift with the aim of maximising the value of patient-level data from clinical trials for the benefi...

journal_title：BMC medical research methodology

authors： Hollis S,Fletcher C,Lynn F,Urban HJ,Branson J,Burger HU,Tudur Smith C,Sydes MR,Gerlinger C

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:How overall physical activity relates to specific activities and how reported activity changes over time may influence interpretation of observed associations between physical activity and health. We examine the relationships between various physical activities self-reported at different times in a large coh...

journal_title：BMC medical research methodology

authors： Armstrong ME,Cairns BJ,Green J,Reeves GK,Beral V,Million Women Study Collaborators.

更新日期：2011-06-22 00:00:00

abstract：BACKGROUND:Greater transparency and, in particular, sharing of patient-level data for further scientific research is an increasingly important topic for the pharmaceutical industry and other organisations who sponsor and conduct clinical trials as well as generally in the interests of patients participating in studies....

journal_title：BMC medical research methodology

authors： Tucker K,Branson J,Dilleen M,Hollis S,Loughlin P,Nixon MJ,Williams Z

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:The Health Care Module of the European Health Interview Survey (EHIS) is aimed to obtain comparable information on the use of inpatient and ambulatory care in all EU member states. In this study we assessed the validity of self-reported information on the use of health care, collected through this instrument...

journal_title：BMC medical research methodology

authors： Van der Heyden J,Charafeddine R,De Bacquer D,Tafforeau J,Van Herck K

更新日期：2016-08-16 00:00:00

abstract：BACKGROUND:Few studies have compared methods to correct for retest effects or practice effects in settings where an acute event could influence test performance, such as major surgery. Our goal in this study was to evaluate the use of different methods to correct for the effects of practice or retest on repeated test a...

journal_title：BMC medical research methodology

authors： Racine AM,Gou Y,Fong TG,Marcantonio ER,Schmitt EM,Travison TG,Inouye SK,Jones RN

更新日期：2018-07-03 00:00:00

abstract：BACKGROUND:Bias in adolescent self-reported height and weight is well documented. Given the importance and widespread use of the National Longitudinal Study of Adolescent to Adult Health (Add Health) data for obesity research, we developed and tested the feasibility and validity of an empirically derived statistical co...

journal_title：BMC medical research methodology

authors： Liechty JM,Bi X,Qu A

更新日期：2016-09-22 00:00:00

abstract：BACKGROUND:The main objective of this paper is to compare different methods for predicting the levels of SO2 air pollution in oil and gas producing area of rural western Canada. Month-long average air quality measurements were collected over a two-year period (2001-2002) at multiple locations, with some side-by-side me...

journal_title：BMC medical research methodology

authors： Burstyn I,Cherry NM,Yasui Y,Kim HM

更新日期：2008-07-04 00:00:00

abstract：BACKGROUND:Health researchers undertake studies which combine qualitative and quantitative methods. Little attention has been paid to the structural issues affecting this mixed methods approach. We explored the facilitators and barriers to undertaking mixed methods studies in health research. METHODS:Face-to-face semi...

journal_title：BMC medical research methodology

authors： O'Cathain A,Nicholl J,Murphy E

更新日期：2009-12-09 00:00:00

abstract：BACKGROUND:Multi-centre randomized controlled clinical trials play an important role in modern evidence-based medicine. Advantages of collecting data from more than one site are numerous, including accelerated recruitment and increased generalisability of results. Mixed models can be applied to account for potential cl...

journal_title：BMC medical research methodology

authors： Harden M,Friede T

更新日期：2018-11-29 00:00:00

abstract：BACKGROUND:The rationale for commissioning community pulmonary rehabilitation programmes is based on evidence from randomised clinical trials. However, there are a number of reasons why similar programmes might be less effective outside the environment of a clinical trial. These include a less highly selected patient g...

journal_title：BMC medical research methodology

authors： Goyder EC,Strong M,Green A,Holmes MW,Miles G,Reddington O,Lawson R,Lee A,Basran G

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:One of the main challenges for drug evaluation in rare diseases is the often heterogeneous course of these diseases. Traditional outcome measures may not be applicable for all patients, when they are in different stages of their disease. For instance, in Duchenne Muscular Dystrophy, the Six Minute Walk Test ...

journal_title：BMC medical research methodology

authors： Gaasterland CM,Jansen-van der Weide MC,Weinreich SS,van der Lee JH

更新日期：2016-08-17 00:00:00

abstract：BACKGROUND:Cancer relapses may be useful to predict the risk of death. To take into account relapse information, the Landmark approach is popular. As an alternative, we propose the joint frailty model for a recurrent event and a terminal event to derive dynamic predictions of the risk of death. METHODS:The proposed pr...

journal_title：BMC medical research methodology

authors： Mauguen A,Rachet B,Mathoulin-Pélissier S,Lawrence GM,Siesling S,MacGrogan G,Laurent A,Rondeau V

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Sickness absence (SA) is an important social, economic and public health issue. Identifying and understanding the determinants, whether biological, regulatory or, health services-related, of variability in SA duration is essential for better management of SA. The conditional frailty model (CFM) is useful whe...

journal_title：BMC medical research methodology

authors： Torá-Rocamora I,Gimeno D,Delclos G,Benavides FG,Manzanera R,Jardí J,Alberti C,Yasui Y,Martínez JM

更新日期：2013-09-16 00:00:00

abstract：BACKGROUND:Diabetes-related lower limb amputations are associated with considerable morbidity and mortality and are usually preceded by foot ulceration. The available systematic reviews of aggregate data are compromised because the primary studies report both adjusted and unadjusted estimates. As adjusted meta-analyses...

journal_title：BMC medical research methodology

authors： Crawford F,Anandan C,Chappell FM,Murray GD,Price JF,Sheikh A,Simpson CR,Maxwell M,Stansby GP,Young MJ,Abbott CA,Boulton AJ,Boyko EJ,Kastenbauer T,Leese GP,Monami M,Monteiro-Soares M,Rith-Najarian SJ,Veves A,Coates N

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:Exposure to unhealthy environments and inadequate child stimulation are main risk factors that affect children's health and wellbeing in low- and middle-income countries. Interventions that simultaneously address several risk factors at the household level have great potential to reduce these negative effect...

journal_title：BMC medical research methodology

authors： Hartinger SM,Nuño N,Hattendorf J,Verastegui H,Karlen W,Ortiz M,Mäusezahl D

更新日期：2020-04-02 00:00:00

abstract：BACKGROUND:Randomised controlled trials (RCTs) are the gold standard for evidence-based practice. However, RCTs can have limitations. For example, translation of findings into practice can be limited by design features, such as inclusion criteria, not accurately reflecting clinical populations. In addition, it is expen...

journal_title：BMC medical research methodology

authors： Lemanska A,Byford RC,Cruickshank C,Dearnaley DP,Ferreira F,Griffin C,Hall E,Hinton W,de Lusignan S,Sherlock J,Faithfull S

更新日期：2020-07-25 00:00:00

abstract：BACKGROUND:Biomarkers of exposures such as infection or environmental chemicals can be measured in small volumes of blood extracted from newborn dried blood spots (DBS) underscoring their potential utility for population-based research. However, few studies have evaluated the feasibility and utility of this resource; p...

journal_title：BMC medical research methodology

authors： Yeung EH,Louis GB,Lawrence D,Kannan K,McLain AC,Caggana M,Druschel C,Bell E

更新日期：2016-02-04 00:00:00

abstract：BACKGROUND:Disease registers aim to collect information about all instances of a disease or condition in a defined population of individuals. Traditionally methods of operating disease registers have required that notifications of cases be identified by unique identifiers such as social security number or national iden...

journal_title：BMC medical research methodology

authors： Churches T

更新日期：2003-01-06 00:00:00