A transdisciplinary team approach to scoping reviews: the case of pediatric polypharmacy.

abstract：BACKGROUND:In low-income settings, key outcomes such as biomarkers or clinical assessments are often missing for a substantial proportion of the study population. The aim of this study was to assess the extent to which Heckman-type selection models can create unbiased estimates in such settings. METHODS:We introduce t...

journal_title：BMC medical research methodology

authors： Koné S,Bonfoh B,Dao D,Koné I,Fink G

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:Motivational Interviewing (MI), Brief Advice (BA) and Health Education (HE) are established smoking cessation induction methods for smokers with low desire to quit. Although randomized controlled trials (RCT's) have been frequently used to assess these interventions the temporal efficacy and effectiveness of...

journal_title：BMC medical research methodology

authors： Bani-Yaghoub M,Elhomani A,Catley D

更新日期：2018-06-13 00:00:00

abstract：BACKGROUND:Although some nonparametric methods have been proposed in the literature to test for the equality of median survival times for censored data in medical research, in general they have inflated type I error rates, which make their use limited in practice, especially when the sample sizes are small. METHODS:In...

journal_title：BMC medical research methodology

authors： Chen Z,Zhang G

更新日期：2016-03-16 00:00:00

abstract：BACKGROUND:Most electronic search efforts directed at identifying primary studies for inclusion in systematic reviews rely on the optimal Boolean search features of search interfaces such as DIALOG and Ovid. Our objective is to test the ability of an Ultraseek search engine to rank MEDLINE records of the included studi...

journal_title：BMC medical research methodology

authors： Sampson M,Barrowman NJ,Moher D,Clifford TJ,Platt RW,Morrison A,Klassen TP,Zhang L

更新日期：2006-02-24 00:00:00

abstract：BACKGROUND:To describe how frequently harm is reported in the abstract of high impact factor medical journals. METHODS: DESIGN AND POPULATION:We carried out a blinded structured review of a random sample of 363 Randomised Controlled Trials (RCTs) carried out on human beings, and published in high impact factor medica...

journal_title：BMC medical research methodology

authors： Bernal-Delgado E,Fisher ES

更新日期：2008-03-27 00:00:00

abstract：BACKGROUND:This paper focuses on measuring the efficiency and effectiveness of two diagramming methods employed in key informant interviews with clinicians and health care administrators. The two methods are 'participatory diagramming', where the respondent creates a diagram that assists in their communication of answe...

journal_title：BMC medical research methodology

authors： Umoquit MJ,Dobrow MJ,Lemieux-Charles L,Ritvo PG,Urbach DR,Wodchis WP

更新日期：2008-08-08 00:00:00

abstract：BACKGROUND:Emergency Departments (EDs) are a first point-of-contact for many youth with mental health and suicidality concerns and can serve as an effective recruitment source for randomized controlled trials (RCTs) of mental health interventions. However, recruitment in acute care settings is impeded by several challe...

journal_title：BMC medical research methodology

authors： Tracey M,Finkelstein Y,Schachter R,Cleverley K,Monga S,Barwick M,Szatmari P,Moretti ME,Willan A,Henderson J,Korczak DJ

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:Multi-centre randomized controlled clinical trials play an important role in modern evidence-based medicine. Advantages of collecting data from more than one site are numerous, including accelerated recruitment and increased generalisability of results. Mixed models can be applied to account for potential cl...

journal_title：BMC medical research methodology

authors： Harden M,Friede T

更新日期：2018-11-29 00:00:00

abstract：BACKGROUND:Estimating costs is essential to the economic analysis of health care programs. Health care costs are often captured from administrative databases or by patient report. Administrative records only provide a partial representation of health care costs and have additional limitations. Patient-completed questio...

journal_title：BMC medical research methodology

authors： Pinto D,Robertson MC,Hansen P,Abbott JH

更新日期：2011-04-13 00:00:00

abstract：BACKGROUND:There are detailed reviews about different recruitment strategies, but not with regard to differences between recruitment of hospital-based versus office-based physicians. Within this study, the two different recruitment schemes are compared. Advantages and disadvantages of different ways of recruitment in r...

journal_title：BMC medical research methodology

authors： Zeissig SR,Weyer-Elberich V,Emrich K,Binder H,Fischbeck S,Imruck BH,Friedrich-Mai P,Beutel ME,Blettner M

更新日期：2017-11-22 00:00:00

abstract：BACKGROUND:Various papers have addressed pros and cons of the stepped wedge cluster randomized trial design (SWD). However, some issues have not or only limitedly been addressed. Our aim was to provide a comprehensive overview of all merits and limitations of the SWD to assist researchers, reviewers and medical ethics ...

journal_title：BMC medical research methodology

authors： de Hoop E,van der Tweel I,van der Graaf R,Moons KG,van Delden JJ,Reitsma JB,Koffijberg H

更新日期：2015-10-30 00:00:00

abstract：BACKGROUND:Functioning and disability are universal human experiences. However, our current understanding of functioning from a comprehensive perspective is limited. The development of the International Classification of Functioning, Disability and Health (ICF) on the one hand and recent developments in graphical model...

journal_title：BMC medical research methodology

authors： Kalisch M,Fellinghauer BA,Grill E,Maathuis MH,Mansmann U,Bühlmann P,Stucki G

更新日期：2010-02-11 00:00:00

abstract：BACKGROUND:In a random effects meta-analysis model, true treatment effects for each study are routinely assumed to follow a normal distribution. However, normality is a restrictive assumption and the misspecification of the random effects distribution may result in a misleading estimate of overall mean for the treatmen...

journal_title：BMC medical research methodology

authors： Yamaguchi Y,Maruo K,Partlett C,Riley RD

更新日期：2017-07-19 00:00:00

abstract：BACKGROUND:A zero-inflated continuous outcome is characterized by occurrence of "excess" zeros that more than a single distribution can explain, with the positive observations forming a skewed distribution. Mixture models are employed for regression analysis of zero-inflated data. Moreover, for repeated measures zero-i...

journal_title：BMC medical research methodology

authors： Mahmud S,Lou WW,Johnston NW

更新日期：2010-06-14 00:00:00

abstract：BACKGROUND:Modern modelling techniques may potentially provide more accurate predictions of binary outcomes than classical techniques. We aimed to study the predictive performance of different modelling techniques in relation to the effective sample size ("data hungriness"). METHODS:We performed simulation studies bas...

journal_title：BMC medical research methodology

authors： van der Ploeg T,Austin PC,Steyerberg EW

更新日期：2014-12-22 00:00:00

abstract：BACKGROUND:Identifying and assessing degree and type of frailty among older persons is a major challenge when targeting high risk populations to identify preventive interventions. The Vulnerable Elders Survey-(VES-13) is a simple instrument to identify frailty defined as risk for death, functional decline or institutio...

journal_title：BMC medical research methodology

authors： Belmin J,Khellaf L,Pariel S,Jarzebowski W,Valembois L,Zeisel J,Lafuente-Lafuente C

更新日期：2020-02-05 00:00:00

abstract：BACKGROUND:Small group research in healthcare is important because it deals with interaction and decision-making processes that can help to identify and improve safer patient treatment and care. However, the number of studies is limited due to time- and resource-intensive data processing. The aim of this study was to e...

journal_title：BMC medical research methodology

authors： Aufegger L,Bicknell C,Soane E,Ashrafian H,Darzi A

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:This article describes the design and baseline sample of a single-site trial comparing Individual Placement and Support (IPS) supported employment delivered within a Veterans Health Administration (VHA) primary care Patient Aligned Care Team (PACT) to treatment-as-usual vocational rehabilitation (TAU-VR) tha...

journal_title：BMC medical research methodology

authors： Davis LL,Blansett CM,Mumba MN,MacVicar D,Toscano R,Pilkinton P,Gay W,Bartolucci A

更新日期：2020-02-17 00:00:00

abstract：BACKGROUND:Quantitative survey of research articles, as an application of bibliometrics, is an effective tool for grasping overall trends in various medical research fields. This type of survey has been also applied to infectious disease research; however, previous studies were insufficient as they underestimated artic...

journal_title：BMC medical research methodology

authors： Takahashi-Omoe H,Omoe K,Okabe N

更新日期：2009-10-06 00:00:00

abstract：BACKGROUND:Cross-cultural research with patient-reported outcomes measures (PROMs) assumes that the PROM in the target language will measure the same construct in the same way as the PROM in the source language. Yet translation methods are rarely used to qualitatively maximise construct equivalence or to describe the i...

journal_title：BMC medical research methodology

authors： Hawkins M,Cheng C,Elsworth GR,Osborne RH

更新日期：2020-05-26 00:00:00

abstract：BACKGROUND:Many biological variables sampled from human subjects show a diurnal pattern, which poses special demands on the techniques used to analyze such data. Furthermore, most biological variables belong to nonlinear dynamical systems, which may make linear statistical techniques less suitable to analyze their dyna...

journal_title：BMC medical research methodology

authors： Toonen RB,Wardenaar KJ,Bos EH,van Ockenburg SL,de Jonge P

更新日期：2018-03-21 00:00:00

abstract：BACKGROUND:Sleeping under a long-lasting insecticidal net (LLIN) is recommended for all pregnant women in sub-Saharan Africa, due to the high prevalence of malaria infection and its associated complications in the region. Despite this, LLIN use has still remained sub-optimal among pregnant women in Maiduguri, Nigeria. ...

journal_title：BMC medical research methodology

authors： Balami AD,Said SM,Zulkefli NAM,Bachok N,Balami EL

更新日期：2019-07-18 00:00:00

abstract：:Clinical Decision Support Systems (CDSS) provide aid in clinical decision making and therefore need to take into consideration human, data interactions, and cognitive functions of clinical decision makers. The objective of this paper is to introduce a high level reference model that is intended to be used as a foundat...

journal_title：BMC medical research methodology

authors： Zikos D,DeLellis N

更新日期：2018-11-16 00:00:00

abstract：BACKGROUND:Due to early colonoscopy for some participants, interval-censored observations can be introduced into the data of a colorectal polyp prevention trial. The censoring could be dependent of risk of recurrence if the reasons of having early colonoscopy are associated with recurrence. This can complicate estimati...

journal_title：BMC medical research methodology

authors： Hsu CH,Long Q,Alberts DS

更新日期：2009-09-29 00:00:00

abstract：BACKGROUND:Competing risks are a common occurrence in survival analysis. They arise when a patient is at risk of more than one mutually exclusive event, such as death from different causes, and the occurrence of one of these may prevent any other event from ever happening. METHODS:There are two main approaches to mode...

journal_title：BMC medical research methodology

authors： Hinchliffe SR,Lambert PC

更新日期：2013-02-06 00:00:00

abstract：BACKGROUND:Quantitative Microbial Risk Assessment (QMRA), a modelling approach, is used to assess health risks. Inputs into the QMRA process include data that characterise the intensity, frequency and duration of exposure to risk(s). Data gaps for water exposure assessment include the duration and frequency of urban no...

journal_title：BMC medical research methodology

authors： O'Toole JE,Sinclair MI,Leder K

更新日期：2009-11-09 00:00:00

abstract：BACKGROUND:Plasma cell dyscrasias (PCD) are a spectrum of disorders resulting from the clonal expansion of plasma cells, ranging from the pre-malignant condition monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM). MM generates a significant burden of disease on the community and it is pr...

journal_title：BMC medical research methodology

authors： Bergin K,Moore E,McQuilten Z,Wood E,Augustson B,Blacklock H,Ho J,Horvath N,King T,McNeil J,Mollee P,Quach H,Reid CM,Rosengarten B,Walker P,Spencer A

更新日期：2016-11-09 00:00:00

abstract：BACKGROUND:Controlled clinical trials of health care interventions are either explanatory or pragmatic. Explanatory trials test whether an intervention is efficacious; that is, whether it can have a beneficial effect in an ideal situation. Pragmatic trials measure effectiveness; they measure the degree of beneficial ef...

journal_title：BMC medical research methodology

authors： Godwin M,Ruhland L,Casson I,MacDonald S,Delva D,Birtwhistle R,Lam M,Seguin R

更新日期：2003-12-22 00:00:00

abstract：BACKGROUND:We would expect information on adverse drug reactions in randomised clinical trials to be easily retrievable from specific searches of electronic databases. However, complete retrieval of such information may not be straightforward, for two reasons. First, not all clinical drug trials provide data on the fre...

journal_title：BMC medical research methodology

authors： Derry S,Loke YK,Aronson JK

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:In longitudinal studies where subjects experience recurrent incidents over a period of time, such as respiratory infections, fever or diarrhea, statistical methods are required to take into account the within-subject correlation. METHODS:For repeated events data with censored failure, the independent increm...

journal_title：BMC medical research methodology

authors： Villegas R,Julià O,Ocaña J

更新日期：2013-07-24 00:00:00