Abstracts in high profile journals often fail to report harm.

abstract：BACKGROUND:The COVID-19 pandemic has evolved into one of the most impactful health crises in modern history, compelling researchers to explore innovative ways to efficiently collect public health data in a timely manner. Social media platforms have been explored as a research recruitment tool in other settings; however...

journal_title：BMC medical research methodology

authors： Ali SH,Foreman J,Capasso A,Jones AM,Tozan Y,DiClemente RJ

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:Controlling the false discovery rate is important when testing multiple hypotheses. To enhance the detection capability of a false discovery rate control test, we applied the likelihood ratio-based multiple testing method in neuroimage data and compared the performance with the existing methods. METHODS:We ...

journal_title：BMC medical research methodology

authors： Lee D,Kang H,Kim E,Lee H,Kim H,Kim YK,Lee Y,Lee DS

更新日期：2015-01-30 00:00:00

abstract：BACKGROUND:The most commonly used survey methods are self-administered questionnaires, telephone interviews, and a mixture of both. But until now evidence out of randomised controlled trials as to whether patient responses differ depending on the survey mode is lacking. Therefore this study assessed whether patient res...

journal_title：BMC medical research methodology

authors： Lungenhausen M,Lange S,Maier C,Schaub C,Trampisch HJ,Endres HG

更新日期：2007-11-22 00:00:00

abstract：:The quality of a consultation provided by a physician can have a profound impact on the quality of care and patient engagement in treatment decisions. When the COPD Assessment Test (CAT) was developed, one of its aims was to aid the communication between physician and patient about the impact of COPD. We developed a n...

journal_title：BMC medical research methodology

authors： Gruffydd-Jones K,Marsden H,Holmes S,Kardos P,Escamilla R,Dal Negro R,Roberts J,Nadeau G,Leather D,Jones P

更新日期：2013-05-10 00:00:00

abstract：BACKGROUND:We developed and validated an automated database case definition for diabetes in children and youth to facilitate pharmacoepidemiologic investigations of medications and the risk of diabetes. METHODS:The present study was part of an in-progress retrospective cohort study of antipsychotics and diabetes in Te...

journal_title：BMC medical research methodology

authors： Bobo WV,Cooper WO,Stein CM,Olfson M,Mounsey J,Daugherty J,Ray WA

更新日期：2012-08-24 00:00:00

abstract：BACKGROUND:Functioning and disability are universal human experiences. However, our current understanding of functioning from a comprehensive perspective is limited. The development of the International Classification of Functioning, Disability and Health (ICF) on the one hand and recent developments in graphical model...

journal_title：BMC medical research methodology

authors： Kalisch M,Fellinghauer BA,Grill E,Maathuis MH,Mansmann U,Bühlmann P,Stucki G

更新日期：2010-02-11 00:00:00

abstract：BACKGROUND:Standard random-effects meta-analysis methods perform poorly when applied to few studies only. Such settings however are commonly encountered in practice. It is unclear, whether or to what extent small-sample-size behaviour can be improved by more sophisticated modeling. METHODS:We consider likelihood-based...

journal_title：BMC medical research methodology

authors： Seide SE,Röver C,Friede T

更新日期：2019-01-11 00:00:00

abstract：BACKGROUND:Retaining participants in cohort studies with multiple follow-up waves is difficult. Commonly, researchers are faced with the problem of missing data, which may introduce biased results as well as a loss of statistical power and precision. The STROBE guidelines von Elm et al. (Lancet, 370:1453-1457, 2007); V...

journal_title：BMC medical research methodology

authors： Karahalios A,Baglietto L,Carlin JB,English DR,Simpson JA

更新日期：2012-07-11 00:00:00

abstract：BACKGROUND:Thresholds for statistical significance are insufficiently demonstrated by 95% confidence intervals or P-values when assessing results from randomised clinical trials. First, a P-value only shows the probability of getting a result assuming that the null hypothesis is true and does not reflect the probabilit...

journal_title：BMC medical research methodology

authors： Jakobsen JC,Gluud C,Winkel P,Lange T,Wetterslev J

更新日期：2014-03-04 00:00:00

abstract：BACKGROUND:There is increasing awareness that meta-analyses require a sufficiently large information size to detect or reject an anticipated intervention effect. The required information size in a meta-analysis may be calculated from an anticipated a priori intervention effect or from an intervention effect suggested b...

journal_title：BMC medical research methodology

authors： Wetterslev J,Thorlund K,Brok J,Gluud C

更新日期：2009-12-30 00:00:00

abstract：BACKGROUND:Self-administered questionnaires are becoming increasingly common in general practice. Much research has explored methods to increase response rates but comparatively few studies have explored the effect of questionnaire administration on reported answers. METHODS:The aim of this study was to determine the ...

journal_title：BMC medical research methodology

authors： Desborough JA,Butters P,Bhattacharya D,Holland RC,Wright DJ

更新日期：2008-06-27 00:00:00

abstract：BACKGROUND:This research aims to explore an identified gap in implementation science methodology, that is, how to assess context in implementation research. Context is among the strongest influences on implementation success but is a construct that is poorly understood and reported within the literature. Consequently, ...

journal_title：BMC medical research methodology

authors： Rogers L,De Brún A,McAuliffe E

更新日期：2020-06-15 00:00:00

abstract：BACKGROUND:Systematic reviewers seek to comprehensively search for relevant studies and summarize these to present the most valid estimate of intervention effectiveness. The more resources searched, the higher the yield, and thus time and costs required to conduct a systematic review. While there is an abundance of evi...

journal_title：BMC medical research methodology

authors： Crumley ET,Wiebe N,Cramer K,Klassen TP,Hartling L

更新日期：2005-08-10 00:00:00

abstract：BACKGROUND:Health researchers undertake studies which combine qualitative and quantitative methods. Little attention has been paid to the structural issues affecting this mixed methods approach. We explored the facilitators and barriers to undertaking mixed methods studies in health research. METHODS:Face-to-face semi...

journal_title：BMC medical research methodology

authors： O'Cathain A,Nicholl J,Murphy E

更新日期：2009-12-09 00:00:00

abstract：BACKGROUND:A key component of the implementation process is identifying potential barriers and facilitators that need to be addressed. The Theoretical Domains Framework (TDF) is one of the most commonly used frameworks for this purpose. When applying the TDF, it is critical to understand the context in which behaviours...

journal_title：BMC medical research methodology

authors： Etherington N,Rodrigues IB,Giangregorio L,Graham ID,Hoens AM,Kasperavicius D,Kelly C,Moore JE,Ponzano M,Presseau J,Sibley KM,Straus S

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:Typically, randomization software should allow users to exert control over the different aspects of randomization including block design, provision of unique identifiers and control over the format and type of program output. While some of these characteristics have been addressed by available software, none...

journal_title：BMC medical research methodology

authors： Saghaei M

更新日期：2004-11-09 00:00:00

abstract：BACKGROUND:Action research (AR) and randomized controlled trials (RCTs) are usually considered to be theoretically and practically incompatible. However, we argue that their respective strengths and weaknesses can be complementary. We illustrate our argument from a recent study assessing the effect of telemonitoring on...

journal_title：BMC medical research methodology

authors： Day K,Kenealy TW,Sheridan NF

更新日期：2016-06-08 00:00:00

abstract：BACKGROUND:Recruitment to health research remains a major challenge. Innovation is required to meet policy commitments to help patients take part in health research. One innovation that may help meet those policy goals is the development of 'consent to contact' systems, where people give generic consent to be contacted...

journal_title：BMC medical research methodology

authors： Grady K,Gibson M,Bower P

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:The aim of this study was to examine the relationship between mortality and statin adherence using two different approaches to adherence measurement (summary versus repeated-measures). METHODS:A retrospective cohort study was conducted using administrative data from Saskatchewan, Canada between 1994 and 200...

journal_title：BMC medical research methodology

authors： Alsabbagh MW,Eurich D,Lix LM,Wilson TW,Blackburn DF

更新日期：2017-04-20 00:00:00

abstract：BACKGROUND:When discussing results medical research articles often tear substantive and statistical (methodical) contributions apart, just as if both were independent. Consequently, reasoning on bias tends to be vague, unclear and superficial. This can lead to over-generalized, too narrow and misleading conclusions, es...

journal_title：BMC medical research methodology

authors： Höfler M,Venz J,Trautmann S,Miller R

更新日期：2018-04-17 00:00:00

abstract：BACKGROUND:Small group research in healthcare is important because it deals with interaction and decision-making processes that can help to identify and improve safer patient treatment and care. However, the number of studies is limited due to time- and resource-intensive data processing. The aim of this study was to e...

journal_title：BMC medical research methodology

authors： Aufegger L,Bicknell C,Soane E,Ashrafian H,Darzi A

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:In clinical trials, study designs may focus on assessment of superiority, equivalence, or non-inferiority, of a new medicine or treatment as compared to a control. Typically, evidence in each of these paradigms is quantified with a variant of the null hypothesis significance test. A null hypothesis is assume...

journal_title：BMC medical research methodology

authors： van Ravenzwaaij D,Monden R,Tendeiro JN,Ioannidis JPA

更新日期：2019-03-29 00:00:00

abstract：BACKGROUND:Quantitative survey of research articles, as an application of bibliometrics, is an effective tool for grasping overall trends in various medical research fields. This type of survey has been also applied to infectious disease research; however, previous studies were insufficient as they underestimated artic...

journal_title：BMC medical research methodology

authors： Takahashi-Omoe H,Omoe K,Okabe N

更新日期：2009-10-06 00:00:00

abstract：BACKGROUND:In longitudinal studies where subjects experience recurrent incidents over a period of time, such as respiratory infections, fever or diarrhea, statistical methods are required to take into account the within-subject correlation. METHODS:For repeated events data with censored failure, the independent increm...

journal_title：BMC medical research methodology

authors： Villegas R,Julià O,Ocaña J

更新日期：2013-07-24 00:00:00

abstract：BACKGROUND:Studies in both paediatric and psychiatric settings often experience problems in recruitment. This can compromise the ability of the study to recruit to target, meaning studies are potentially underpowered. It can also result in a biased sample if a non-representative group are selectively recruited. Recruit...

journal_title：BMC medical research methodology

authors： Loades ME,Smith L,Higson-Sweeney N,Beasant L,Stallard P,Kessler D,Crawley E

更新日期：2019-04-27 00:00:00

abstract：BACKGROUND:One of the main challenges for drug evaluation in rare diseases is the often heterogeneous course of these diseases. Traditional outcome measures may not be applicable for all patients, when they are in different stages of their disease. For instance, in Duchenne Muscular Dystrophy, the Six Minute Walk Test ...

journal_title：BMC medical research methodology

authors： Gaasterland CM,Jansen-van der Weide MC,Weinreich SS,van der Lee JH

更新日期：2016-08-17 00:00:00

abstract：BACKGROUND:Aboriginal and Torres Strait Islander peoples are under-reported in administrative health datasets in NSW, Australia. Correct reporting of Aboriginal and Torres Strait Islander peoples is essential to measure the effectiveness of policies and programmes aimed at reducing the health disadvantage experienced b...

journal_title：BMC medical research methodology

authors： Taylor LK,Bentley J,Hunt J,Madden R,McKeown S,Brandt P,Baker D

更新日期：2012-07-02 00:00:00

abstract：:Clinical Decision Support Systems (CDSS) provide aid in clinical decision making and therefore need to take into consideration human, data interactions, and cognitive functions of clinical decision makers. The objective of this paper is to introduce a high level reference model that is intended to be used as a foundat...

journal_title：BMC medical research methodology

authors： Zikos D,DeLellis N

更新日期：2018-11-16 00:00:00

abstract：BACKGROUND:Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a rare disease with extreme between-subject variability, especially with respect to rate of disease progression. This makes modelling a subject's disease progression, which is measured by the ALS Functional Rating Scale (ALSFRS), ver...

journal_title：BMC medical research methodology

authors： Karanevich AG,Statland JM,Gajewski BJ,He J

更新日期：2018-02-06 00:00:00

abstract：BACKGROUND:This paper discusses whether baseline demographic, socio-economic, health variables, length of follow-up and method of contacting the participants predict non-response to the invitation for a second assessment of lifestyle factors and body weight in the European multi-center EPIC-PANACEA study. METHODS:Over...

journal_title：BMC medical research methodology

authors： May AM,Adema LE,Romaguera D,Vergnaud AC,Agudo A,Ekelund U,Steffen A,Orfanos P,Slimani N,Rinaldi S,Mouw T,Rohrmann S,Hermann S,Boeing H,Bergmann MM,Jakobsen MU,Overvad K,Wareham NJ,Gonzalez C,Tjonneland A,Halkjaer

更新日期：2012-09-24 00:00:00