Venous invasion as a risk factor for recurrence after gastrectomy followed by chemotherapy for stage III gastric cancer.

abstract：BACKGROUND:HIV infection is associated with a higher incidence of precancerous cervical lesions and their progression to invasive cervical cancer (ICC). Zambia is a global epicenter of HIV and ICC, yet the overall burden of cervical pre-cancer [cervical intraepithelial neoplasia 3 (CIN3)] and ICC among its HIV positive...

journal_title：BMC cancer

authors： Bateman AC,Katundu K,Mwanahamuntu MH,Kapambwe S,Sahasrabuddhe VV,Hicks ML,Chi BH,Stringer JS,Parham GP,Chibwesha CJ

更新日期：2015-07-24 00:00:00

abstract：BACKGROUND:Art therapy may improve the physical, mental, and emotional wellbeing of individuals for a variety of purposes. It remains understudied and underutilized in cancer care. We sought to determine the ability of a pilot art therapy program to improve the physical, mental, and emotional well-being of cancer patie...

journal_title：BMC cancer

authors： Elimimian EB,Elson L,Stone E,Butler RS,Doll M,Roshon S,Kondaki C,Padgett A,Nahleh ZA

更新日期：2020-09-22 00:00:00

abstract：BACKGROUND:To date, the clinical benefit of topical steroid use has only been demonstrated for radiation dermatitis induced by 50-60 Gy irradiation in breast cancer. However, these agents are also often used clinically for the control of radiation dermatitis induced by high-dose (>60Gy) irradiation with chemotherapy in...

journal_title：BMC cancer

authors： Zenda S,Yamaguchi T,Yokota T,Miyaji T,Mashiko T,Tanaka M,Yonemura M,Takeno M,Okano T,Kawasaki T,Nakamori Y,Ishii S,Shimada S,Kanamaru M,Uchitomi Y

更新日期：2018-09-06 00:00:00

abstract：BACKGROUND:Twist, a transcription factor of the basic helix-loop-helix class, is reported to regulate cancer metastasis. It is known to induce epithelial-mesenchymal transition (EMT). In this study, we evaluated the expression of twist and its effect on cell migration in hepatocellular carcinoma (HCC). METHODS:We exam...

journal_title：BMC cancer

authors： Matsuo N,Shiraha H,Fujikawa T,Takaoka N,Ueda N,Tanaka S,Nishina S,Nakanishi Y,Uemura M,Takaki A,Nakamura S,Kobayashi Y,Nouso K,Yagi T,Yamamoto K

更新日期：2009-07-18 00:00:00

abstract：BACKGROUND:Lung adenocarcinoma (LUAD) is one of the most common cancer types, threatening the human health around the world. However, the high heterogeneity and complexity of LUAD limit the benefits of targeted therapies. This study aimed to identify the key prognosis impacting genes and relevant subtypes for LUAD. ME...

journal_title：BMC cancer

authors： Lv Z,Lei T

更新日期：2020-01-27 00:00:00

abstract：BACKGROUND:Non-muscle invasive bladder cancer (NMIBC) is usually treated with local therapy including transurethral resection of the bladder tumor and intravesical therapy depending on the stage of the tumor. NMIBC is a rarely a metastatic diseases with lymph node invasion in less of 10%. In the other hand meningeal ca...

journal_title：BMC cancer

authors： Teyssonneau D,Daste A,Dousset V,Hoepffner JL,Ravaud A,Gross-Goupil M

更新日期：2017-05-11 00:00:00

abstract：BACKGROUND:We evaluated if the survival benefit of adding rituximab to standard chemotherapy for non-Hodgkin lymphoma (NHL) observed in clinical trials has been experienced by an Australian NHL patient population. METHODS:NHL cases diagnosed in 1985-2004 in New South Wales (NSW) were followed-up to the end of 2004. Ri...

journal_title：BMC cancer

authors： Yu XQ,Chen WH,O'Connell DL

更新日期：2010-05-24 00:00:00

abstract：BACKGROUND:Uterine leiomyosarcoma (ULMS) is an aggressive form of soft tissue tumors. The molecular heterogeneity and pathogenesis of ULMS are not well understood. METHODS:Expression profiling data were used to determine the possibility and optimal number of ULMS molecular subtypes. Next, clinicopathological character...

journal_title：BMC cancer

authors： An Y,Wang S,Li S,Zhang L,Wang D,Wang H,Zhu S,Zhu W,Li Y,Chen W,Ji S,Guo X

更新日期：2017-09-11 00:00:00

abstract：BACKGROUND:Cationic antimicrobial peptides (CAPs) with antitumor activity constitute a promising group of novel anticancer agents. These peptides induce lysis of cancer cells through interactions with the plasma membrane. It is not known which cancer cell membrane components influence their susceptibility to CAPs. We h...

journal_title：BMC cancer

authors： Fadnes B,Rekdal O,Uhlin-Hansen L

更新日期：2009-06-15 00:00:00

abstract：BACKGROUND:To characterize prognostic and risk factors of central nervous system (CNS) metastases in patients with epithelial ovarian cancer (EOC). METHODS:A retrospective analysis of Xijing Hospital electronic medical records was conducted to identify patients with pathologically confirmed EOC and CNS metastases. In ...

journal_title：BMC cancer

authors： Liu BL,Liu SJ,Baskys A,Cheng H,Han Y,Xie C,Song H,Li J,Xin XY

更新日期：2014-11-17 00:00:00

abstract：BACKGROUND:Nasopharyngeal carcinoma (NPC) is a type of head-neck cancer with a distinguishable geographic and racial distribution worldwide. Increasing evidence supports that the accumulation of additional genetic and epigenetic abnormalities is important in driving the NPC tumorigenic process. In this study, we aim to...

journal_title：BMC cancer

authors： Huang PY,Zeng TT,Ban X,Li MQ,Zhang BZ,Zhu YH,Hua WF,Mai HQ,Zhang L,Guan XY,Li Y

更新日期：2016-08-22 00:00:00

abstract：BACKGROUND:The centralisation of specialist cancer surgical services across London Cancer and Greater Manchester Cancer, England, may significantly change how patients experience care. These centres are changing specialist surgical pathways for several cancers including prostate, bladder, kidney, and oesophago-gastric ...

journal_title：BMC cancer

authors： Melnychuk M,Vindrola-Padros C,Aitchison M,Clarke CS,Fulop NJ,Levermore C,Maddineni SB,Moore CM,Mughal MM,Perry C,Pritchard-Jones K,Ramsay AIG,Shackley D,Vickers J,Morris S

更新日期：2018-02-27 00:00:00

abstract：BACKGROUND:Epidemiological studies show that cigarette smoking increase the risk of nasopharyngeal carcinoma (NPC), however, whether other common, potentially adverse household inhalants increase NPC risk remains uncertain. METHODS:We conducted a large case-control study to explore the effects of household inhalants, ...

journal_title：BMC cancer

authors： He YQ,Xue WQ,Shen GP,Tang LL,Zeng YX,Jia WH

更新日期：2015-12-29 00:00:00

abstract：BACKGROUND:The association of genes XRCC1, TP53 and MDM2 with breast cancer (BC) has never been tested in Kyrgyz population. We, therefore, aimed to identify an association of alleles and genotypes of polymorphic markers Arg399Gln of gene XRCC1, Arg72Pro of gene TP53, and T309G of gene MDM2 with the risk of BC in Kyrgy...

journal_title：BMC cancer

authors： Isakova J,Talaibekova E,Aldasheva N,Vinnikov D,Aldashev A

更新日期：2017-11-13 00:00:00

abstract：BACKGROUND:Limited studies examine the immune landscape in Esophageal Adenocarcinoma (EAC). We aim to identify novel associations, which may inform immunotherapy treatment stratification. METHODS:Three hundred twenty-nine EAC cases were available in Tissue Microarrays (TMA) format. A discovery cohort of 166 EAC cases ...

journal_title：BMC cancer

authors： Humphries MP,Craig SG,Kacprzyk R,Fisher NC,Bingham V,McQuaid S,Murray GI,McManus D,Turkington RC,James J,Salto-Tellez M

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:TGFβ signaling has typically been associated with suppression of tumor initiation while the role it plays in metastasis is generally associated with progression of malignancy. However, we present evidence here for an anti-metastatic role of TGFβ signaling. METHODS:To test the importance of TGFβ signaling to...

journal_title：BMC cancer

authors： Simms NA,Rajput A,Sharratt EA,Ongchin M,Teggart CA,Wang J,Brattain MG

更新日期：2012-06-06 00:00:00

abstract：BACKGROUND:Free flap-mediated gene therapy in the tumor bed following surgical resection is a promising approach in cancer targeted treatment of residual disease. We investigated the selective killing efficacy of a lentivirus-mediated cytosine deaminase-thymidine kinase (CDglyTK) gene in transplanted breast cancer deli...

journal_title：BMC cancer

authors： Zhang J,Liu Y,Zang M,Zhu S,Chen B,Li S,Xue B,Yan L

更新日期：2019-09-14 00:00:00

abstract：BACKGROUND:PRDM5 is an epigenetic regulator that has been recognized as an important tumour suppressor gene. Silencing of PRDM5 by promoter hypermethylation has been demonstrated in several cancer types and PRDM5 loss results in upregulation of the Wnt pathway and increased cellular proliferation. PRDM5 has not been ex...

journal_title：BMC cancer

authors： Bond CE,Bettington ML,Pearson SA,McKeone DM,Leggett BA,Whitehall VL

更新日期：2015-01-23 00:00:00

abstract：BACKGROUND:Li-Fraumeni syndrome (LFS) is a hereditary cancer predisposition syndrome that is commonly associated with a germline mutation in the tumor suppressor gene p53. Loss of p53 results in increased expression of CD44, a cancer stem cell (CSC) marker, which is involved in the scavenging of reactive oxygen species...

journal_title：BMC cancer

authors： Yoshida GJ,Fuchimoto Y,Osumi T,Shimada H,Hosaka S,Morioka H,Mukai M,Masugi Y,Sakamoto M,Kuroda T

更新日期：2012-10-02 00:00:00

abstract：BACKGROUND:Platelets are frequently altered in hepatocellular carcinoma (HCC) patients. Platelet lysates (hPL) can enhance HCC cell growth and decrease apoptosis. The aims were to evaluate whether hPL can modulate the actions of sorafenib or regorafenib, two clinical HCC multikinase antagonists. METHODS:Several human ...

journal_title：BMC cancer

authors： D'Alessandro R,Refolo MG,Lippolis C,Giannuzzi G,Carella N,Messa C,Cavallini A,Carr BI

更新日期：2014-05-21 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) have become the mainstay of treatment for advanced renal cell carcinoma (RCC), but it has been unclear whether the antitumor effect of TKIs depends on the organ where the RCC metastasis is located. We previously reported that the FDG accumulation assessed by FDG PET/CT, was ...

journal_title：BMC cancer

authors： Kakizoe M,Yao M,Tateishi U,Minamimoto R,Ueno D,Namura K,Makiyama K,Hayashi N,Sano F,Kishida T,Kobayashi K,Noguchi S,Ikeda I,Ohgo Y,Taguri M,Morita S,Inoue T,Kubota Y,Nakaigawa N

更新日期：2014-06-02 00:00:00

abstract：BACKGROUND:Following the recommendation of lung cancer screening in the US, screening committees in several European countries are reviewing the evidence for implementing national programmes. However, inadequate participation from high-risk groups poses a potential barrier to its effectiveness. The present study examin...

journal_title：BMC cancer

authors： Quaife SL,Vrinten C,Ruparel M,Janes SM,Beeken RJ,Waller J,McEwen A

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Hyaluronan (HA) an important component of the extracellular matrix, has been linked to tumor progression and drug resistance in several malignancies. However, limited data is available for ovarian cancer. This study investigated the role of hyaluronan (HA) and a potential link between the HA-CD44 pathway and...

journal_title：BMC cancer

authors： Ricciardelli C,Ween MP,Lokman NA,Tan IA,Pyragius CE,Oehler MK

更新日期：2013-10-14 00:00:00

abstract：BACKGROUND:The development of non-small cell lung carcinoma proceeds through a series of well-defined pathological steps before the appearance of invasive lung carcinoma. The molecular changes that correspond with pathology changes are not well defined and identification of the molecular events may provide clues on the...

journal_title：BMC cancer

authors： Tichelaar JW,Zhang Y,leRiche JC,Biddinger PW,Lam S,Anderson MW

更新日期：2005-12-06 00:00:00

abstract：BACKGROUND:Thyroid cancer is among the fastest growing malignancies; almost fifty-percent of these rapidly increasing incidence tumors are less than or equal to 1cm in size, termed papillary thyroid microcarcinoma (PTMC). The management of PTMC remains a controversy due to differing natural history of these patients. E...

journal_title：BMC cancer

authors： Kunavisarut T,Kak I,Macmillan C,Ralhan R,Walfish PG

更新日期：2012-11-15 00:00:00

abstract：BACKGROUND:Cancer patient pathways (CPPs) were implemented in 2015 to reduce waiting time, regional variation in waiting time, and to increase the predictability of cancer care for the patients. The aims of this study were to see if the national target of 70% of all cancer patients being included in a CPP was met, and ...

journal_title：BMC cancer

authors： Nilssen Y,Brustugun OT,Eriksen MT,Haug ES,Naume B,Møller B

更新日期：2020-05-30 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMPs) are crucially involved in the regulation of multiple stages of cancer progression. Elevated MMP levels have been associated with the development of metastases and poor prognosis in several types of cancer. However, the role of MMPs in osteosarcoma and their prognostic value i...

journal_title：BMC cancer

authors： Kunz P,Sähr H,Lehner B,Fischer C,Seebach E,Fellenberg J

更新日期：2016-03-15 00:00:00

abstract：BACKGROUND:Extramammary Paget's disease (EMPD) remains a rare condition with only a limited number of cases reported in the literature. EMPD is mainly composed of intraepidermal Paget cells, and possesses variable clinical behaviors and histological appearances, leading to difficulty in the diagnosis of this disease. ...

journal_title：BMC cancer

authors： Wang X,Yang W,Yang J

更新日期：2010-08-04 00:00:00

abstract：BACKGROUND:Cancer of unknown primary remains a mallignancy of elusive biology and grim prognosis that lacks effective therapeutic options. We investigated angiogenesis in cancer of unknown primary to expand our knowledge on the biology of these tumors and identify potential therapeutic targets. METHODS:Paraffin embedd...

journal_title：BMC cancer

authors： Karavasilis V,Malamou-Mitsi V,Briasoulis E,Tsanou E,Kitsou E,Kalofonos H,Fountzilas G,Fotsis T,Pavlidis N

更新日期：2005-03-03 00:00:00

abstract：BACKGROUND:Metformin and the thiazolidinediones (TZDs) may have a protective effect against the development of lung cancer. METHODS:Patients with diabetes mellitus (DM) were identified from the electronic medical records of the Cleveland Clinic. Diabetics with lung cancer were identified then verified by direct review...

journal_title：BMC cancer

authors： Mazzone PJ,Rai H,Beukemann M,Xu M,Jain A,Sasidhar M

更新日期：2012-09-14 00:00:00