Abstract:
BACKGROUND:The present study aimed to compare the intravenous bolus effect of oxycodone and fentanyl on hemodynamic response after endotracheal intubation and postoperative pain in patients undergoing closed reduction of nasal bone fracture. METHODS:In this prospective randomized double-blinded study, 64 patients undergoing closed reduction of nasal bone fracture were randomized into one of two groups: the fentanyl group (Group F) or the oxycodone group (Group O). Each drug (fentanyl 2 mcg/kg in Group F and oxycodone 0.2 mg/kg in Group O) was administered prior to the induction of general anesthesia. Hemodynamic changes after endotracheal intubation and postoperative pain were then measured in both groups. RESULTS:There was no significant difference in the change in mean arterial pressure and heart rate between pre-induction and post-intubation in both Groups F and O (P > 0.05). Postoperative pain in Group O was milder than that in Group F (P < 0.001); however, time to awakening from the end of operation was shorter in Group F (P = 0.012). CONCLUSION:In patients undergoing closed reduction of nasal bone fracture, oxycodone attenuates hemodynamic response to endotracheal intubation similar to fentanyl. However, oxycodone is more effective than fentanyl in improving postoperative pain. TRIAL REGISTRATION:Clinical Research Information Service (Trial registry number: KCT0001153 ) on 3 July, 2014.
journal_name
BMC Anesthesioljournal_title
BMC anesthesiologyauthors
Lee YS,Baek CW,Kim DR,Kang H,Choi GJ,Park YH,Kim WJ,Jung YH,Woo YCdoi
10.1186/s12871-016-0279-xsubject
Has Abstractpub_date
2016-11-17 00:00:00pages
115issue
1issn
1471-2253pii
10.1186/s12871-016-0279-xjournal_volume
16pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Induction of the COX-2 isoenzyme appears to play a major role in the genesis of central sensitization after nociceptive stimulation. This study aimed to investigate the efficacy of a single, oral dose of the specific COX-2 inhibitor-valdecoxib in attenuating the central sensitization - induced secondary hype...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-6-3
更新日期:2006-03-10 00:00:00
abstract:BACKGROUND:Quick and complete recovery of cognitive function after general anesthesia is desirable, particularly for working-age patients. Desflurane is less likely to have long-term effects than older-generation inhalational anesthetics, however, its short-term effects have not been fully investigated. Our objective w...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-019-0793-8
更新日期:2019-07-04 00:00:00
abstract:BACKGROUND:As defined by evidence-based medicine randomized controlled trials rank higher than observational studies in the hierarchy of clinical research. Accordingly, when assessing the effects of treatments on patient outcomes, there is a tendency to focus on the study method rather than also appraising the key elem...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-016-0264-4
更新日期:2016-10-14 00:00:00
abstract:BACKGROUND:The role of N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) as a prognostic factor in patients admitted to the intensive care unit (ICU) is not yet fully established. We aimed to determine whether NT-pro-BNP is predictive of ICU mortality in a multicenter cohort of critically ill patients. METHODS:A ...
journal_title:BMC anesthesiology
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2253-14-16
更新日期:2014-03-10 00:00:00
abstract:BACKGROUND:Intracranial-pressure (ICP) monitoring is useful for patients with increased ICP following hemorrhagic stroke. In this study, the changes in pressure gradients between the two cerebral hemispheres were investigated after hemorrhagic stroke of one side, and after a craniotomy. METHODS:Twenty-four patients wi...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-14-112
更新日期:2014-12-03 00:00:00
abstract:BACKGROUND:Transpulmonary thermodilution (TPTD) derived parameters are used to direct fluid management in ICU-patients. Extravascular lung water EVLW and its ratio to pulmonary blood volume (pulmonary vascular permeability index PVPI) have been associated with mortality. In single indicator TPTD pulmonary blood volume ...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-14-81
更新日期:2014-09-24 00:00:00
abstract:BACKGROUND:The present anonymous multicenter online survey was conducted to evaluate the application of regional anaesthesia techniques as well as the used local anaesthetics and adjuncts at German and Austrian university hospitals. METHODS:39 university hospitals were requested to fill in an online questionnaire, to ...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-10-4
更新日期:2010-04-17 00:00:00
abstract:BACKGROUND:Low-flow sevoflurane anesthesia has been shown to influence renal function in rats, but not in adult humans. Presently, no study has assessed the effects of sevoflurane on renal function in low birth weight infants. Our aim was to study the renal function in low birth weight infants undergoing surgery with l...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-15-6
更新日期:2015-01-21 00:00:00
abstract:BACKGROUND:Fentanyl and remifentanil are widely used opioids in surgery, but it has not been evaluated whether the choice of opioids during surgery affects the patients' postoperative quality of recovery. Accordingly, we aim to compare postoperative recovery of fentanyl-based anesthesia with remifentanil-based anesthes...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-018-0547-z
更新日期:2018-07-11 00:00:00
abstract:BACKGROUND:Sugammadex is a modified gamma-cyclodextrin that acts by selectively encapsulating free amino-steroidal neuromuscular relaxants. Several case reports have been published on the use of sugammadex in patients with neuromuscular disorders that include neuromuscular junction diseases, myopathies, neuropathies, a...
journal_title:BMC anesthesiology
pub_type: 杂志文章
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更新日期:2019-11-19 00:00:00
abstract:BACKGROUND:Laryngeal mask airway is a supraglottic airway device which has led to a fundamental change in the management of modern general anesthesia. In the present study; we evaluated the laryngeal mask airway insertion conditions and hemodynamic changes comparing ketamine-propofol mixture (ketofol) with propofol. Th...
journal_title:BMC anesthesiology
pub_type: 杂志文章
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更新日期:2019-03-20 00:00:00
abstract:BACKGROUND:The sensory innervation of the shoulder is complex and there are variations in the branching patterns of the sensory fibres. Articular branches from the axillary nerve to the subacromial bursa are described in more than 50% of investigated shoulders but the isolated contribution of sensory input from the axi...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
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更新日期:2020-01-31 00:00:00
abstract:BACKGROUND:The frequency of malpositioning of gastric tubes in the trachea has been reported to be 0.3-15%, which may cause severe complications, such as pneumonia, if not detected promptly. If a gastric tube can be guided into the esophagus under direct vision with a video laryngoscope, misplacement of the gastric tub...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2253-14-82
更新日期:2014-09-25 00:00:00
abstract:BACKGROUND:The benefits of lung-protective ventilation (LPV) with a low tidal volume (6 mL/kg of ideal body weight [IBW]), limited plateau pressure (< 28-30 cm H2O), and appropriate positive end-expiratory pressure (PEEP) in patients with acute respiratory distress syndrome have become apparent and it is now widely ado...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-018-0495-7
更新日期:2018-04-02 00:00:00
abstract:BACKGROUND:This study investigated the effect of different degrees of passive leg raising (PLR) on the internal jugular vein (IJV) cross-sectional area (CSA) and on the success rate of IJV cannulation in patients waiting for thoracic surgery, to analyze whether body mass index (BMI), gender, age, fasting time and preop...
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pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-019-0751-5
更新日期:2019-05-17 00:00:00
abstract:BACKGROUND:Mismanagement of remifentanil leads to severe side effects such as opioid-induced tolerance and hyperalgesia. Recently studies revealed an alternative withdrawal method to limit these side effects. A gradual withdrawal of remifentanil seems to be associated with less pain. The hypothesis of this double-blind...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-019-0731-9
更新日期:2019-04-25 00:00:00
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journal_title:BMC anesthesiology
pub_type: 杂志文章
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更新日期:2015-10-15 00:00:00
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更新日期:2018-05-10 00:00:00
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更新日期:2019-10-31 00:00:00
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更新日期:2019-01-17 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2019-08-14 00:00:00
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journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
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更新日期:2017-12-08 00:00:00
abstract:BACKGROUND:There are doubts among anesthesiologists on the use of the Laryngeal Mask Airway (LMA) in nasal surgeries because of concerns about the occurrence of blood leakages to the airway. We hypothesized that the use of LMA-Supreme (LMA-S) in nasal surgery is comparable with endotracheal tube (ETT) according to airw...
journal_title:BMC anesthesiology
pub_type: 杂志文章
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更新日期:2021-01-07 00:00:00
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journal_title:BMC anesthesiology
pub_type: 杂志文章
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更新日期:2017-12-19 00:00:00
abstract:BACKGROUND:Compared to conventional tidal volume ventilation, low tidal-volume ventilation reduces mortality in cased of acute respiratory distress syndrome. The aim of the present study is to determine whether low tidal-volume ventilation reduces the production of inflammatory mediators in the lungs and improves physi...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-016-0209-y
更新日期:2016-07-30 00:00:00
abstract:BACKGROUND:Carbon monoxide (CO) poisoning can be a life threatening condition. Systemic hyperbaric oxygen (HBO) therapy is used to induce CO detoxification. However, little is known about the hemodynamic response to HBO in severely intoxicated patients. METHODS:We retrospectively analyzed the medical records of 6 CO-p...
journal_title:BMC anesthesiology
pub_type: 杂志文章
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更新日期:2013-09-27 00:00:00
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journal_title:BMC anesthesiology
pub_type: 杂志文章
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更新日期:2014-12-20 00:00:00
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journal_title:BMC anesthesiology
pub_type: 杂志文章
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更新日期:2020-12-14 00:00:00
abstract:BACKGROUND:Conventionally, ultrasonographic assessment of diaphragm contractility has involved measuring respiratory changes in diaphragm thickness (thickening fraction) using B-mode or caudal displacement with M-mode. Two-dimensional speckle-tracking has been increasingly used to assess muscle deformation ('strain') i...
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pub_type: 临床试验,杂志文章
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更新日期:2016-07-25 00:00:00