Ketamine exacerbates cortical neuroapoptosis under hyperoxic conditions by upregulating expression of the N-methyl-D-aspartate receptor subunit NR1 in the developing rat brain.

abstract：BACKGROUND:In the immediate postoperative period, obese patients are more likely to exhibit hypoxaemia due to atelectasis and impaired respiratory mechanics, changes which can be attenuated by non-invasive ventilation (NIV). The aim of the study was to evaluate the duration of any effects of early initiation of short t...

journal_title：BMC anesthesiology

authors： Zoremba M,Kalmus G,Begemann D,Eberhart L,Zoremba N,Wulf H,Dette F

更新日期：2011-05-23 00:00:00

abstract：BACKGROUND:Increase of pulmonary vascular resistance (PVR) is an efficient method of modulating pulmonary and systemic blood flows (Qp/Qs) for patients with left-to-right (L-R) shunt, and is also closely associated with insufficient oxygen exchange for pulmonary hypoperfusion. So that it might be a preferred regime of ...

journal_title：BMC anesthesiology

authors： Li P,Zeng J,Wei W,Lin J

更新日期：2019-10-09 00:00:00

abstract：BACKGROUND:Desflurane during early reperfusion has been shown to postcondition human myocardium, in vitro. We investigated the role of adenosine and bradykinin receptors, and generation of radical oxygen species in desflurane-induced postconditioning in human myocardium. METHODS:We recorded isometric contraction of hu...

journal_title：BMC anesthesiology

authors： Lemoine S,Buléon C,Rouet R,Ivascau C,Babatasi G,Massetti M,Gérard JL,Hanouz JL

更新日期：2010-07-29 00:00:00

abstract：BACKGROUND:Post-dural puncture headache (PDPH) due to excessive cerebrospinal fluid (CSF) leakage is a well-known complication of lumbar puncture. Although various factors, especially the type of spinal needle, have been demonstrated to be associated with PDPH, the clinical implications of CSF leakage detected on magne...

journal_title：BMC anesthesiology

authors： Sakurai K,Matsukawa N,Okita K,Nishio M,Shimohira M,Ozawa Y,Kobayashi S,Yamawaki T,Shibamoto Y

更新日期：2013-10-27 00:00:00

abstract：BACKGROUND:As defined by evidence-based medicine randomized controlled trials rank higher than observational studies in the hierarchy of clinical research. Accordingly, when assessing the effects of treatments on patient outcomes, there is a tendency to focus on the study method rather than also appraising the key elem...

journal_title：BMC anesthesiology

authors： Trentino K,Farmer S,Gross I,Shander A,Isbister J

更新日期：2016-10-14 00:00:00

abstract：:BACKGROUND: We report a case of a patient with apparent resistance to local anesthetics. While similar cases of failure of regional anesthetics are often attributed to technical failure, the overall clinical presentation and history of this patient suggests a true resistance to local anesthetics. CASE PRESENTATION: Th...

journal_title：BMC anesthesiology

authors： Kavlock R,Ting PH

更新日期：2004-01-16 00:00:00

abstract：BACKGROUND:About one third of hospital mortality in critically ill patients occurs after Intensive Care Unit (ICU) discharge. Some authors have recently hypothesized that unresolved or latent inflammation and sepsis may be an important factor that contributes to death following successful discharge from the ICU. AIM:T...

journal_title：BMC anesthesiology

authors： Silvestre J,Coelho L,Póvoa P

更新日期：2010-09-27 00:00:00

abstract：BACKGROUND:Current evidence regarding the efficacy of ethanol locks in preventing catheter-related bloodstream infection (CRBI) is inconclusive. METHODS:Electronic databases, including PubMed, Web of Science, Embase, and the Cochrane Library (until April 2018),were systematically searched for relevant studies. Two rev...

journal_title：BMC anesthesiology

authors： Zhang P,Lei JH,Su XJ,Wang XH

更新日期：2018-07-24 00:00:00

abstract：BACKGROUND:The role of N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) as a prognostic factor in patients admitted to the intensive care unit (ICU) is not yet fully established. We aimed to determine whether NT-pro-BNP is predictive of ICU mortality in a multicenter cohort of critically ill patients. METHODS:A ...

journal_title：BMC anesthesiology

authors： Rhee CK,Lim SY,Koh SO,Choi WI,Lee YJ,Chon GR,Kim JH,Kim JY,Lim J,Park S,Kim HC,Lee JH,Lee JH,Park J,Koh Y,Suh GY,Kim SC,Validation of Simplified acute physiology score3 in Korean Intensive care unit (VSKI) study group &

更新日期：2014-03-10 00:00:00

abstract：BACKGROUND:Despite international data indicating that Enhanced Recovery After Surgery (ERAS) programs, which combine evidence-based perioperative strategies, expedite recovery after surgery, few centers have successfully adopted this approach within the U.S. We describe the implementation and efficacy of an ERAS progra...

journal_title：BMC anesthesiology

authors： Sarin A,Litonius ES,Naidu R,Yost CS,Varma MG,Chen LL

更新日期：2016-08-03 00:00:00

abstract：BACKGROUND:Isoflurane-induced neuroapoptosis and cognitive impairment has been previously reported. Hydrogen sulfide (H2S) has been shown to be a neuromodulator that is thought to have anti-apoptotic, anti-inflammatory, and anti-oxidative benefits. However, it is not known if H2S is protective against anesthesia-induce...

journal_title：BMC anesthesiology

authors： Hu X,Luan L,Guan W,Zhang S,Li B,Ji W,Fan H

更新日期：2017-09-05 00:00:00

abstract：:BACKGROUND: Propofol is widely used for both short-term anesthesia and long-term sedation. It has unusual pharmacokinetics because of its high lipid solubility. The standard approach to describing the pharmacokinetics is by a multi-compartmental model. This paper presents the first detailed human physiologically based...

journal_title：BMC anesthesiology

authors： Levitt DG,Schnider TW

更新日期：2005-04-22 00:00:00

abstract：BACKGROUND:Perioperative immune function plays an important role in the prognosis of patients. Several studies have indicated that low-dose opioid receptor blockers can improve immune function. METHODS:Sixty-nine patients undergoing video-assisted thoracoscopic resection of the lung cancer were randomly assigned to ei...

journal_title：BMC anesthesiology

authors： Lin Y,Miao Z,Wu Y,Ge FF,Wen QP

更新日期：2019-12-19 00:00:00

abstract：BACKGROUND:Hyperthermia is relatively rare during general anesthesia; however, a few studies have been conducted on hyperthermia and the neuromuscular blockade (NMB) induced by rocuronium, and the reversal of NMB by sugammadex. We investigated the effect of hyperthermia status on the NMB induced by rocuronium, and its ...

journal_title：BMC anesthesiology

authors： Kim JS,Kim YM,Kim HJ,Choi JM,Kim YB,Song JS,Yang HS

更新日期：2020-08-07 00:00:00

abstract：BACKGROUND:Carbohydrate-rich liquid drinks (CRLDs) have been recommended to attenuate insulin resistance by shortening the preoperative fasting interval. The aim of our study the effect of preoperative oral administration of CRLDs on the well-being and clinical status of patients. METHODS:A randomized, double blind, p...

journal_title：BMC anesthesiology

authors： Sada F,Krasniqi A,Hamza A,Gecaj-Gashi A,Bicaj B,Kavaja F

更新日期：2014-10-17 00:00:00

abstract：BACKGROUND:Sugammadex, a γ-cyclodextrin derivative, belongs to a new class of selective relaxant binding agents. Sugammadex was approved 10-years ago by the European medicines agency and today is used in clinical anesthesia and emergency medicine globally. In this review, indications for neuromuscular block, the challe...

journal_title：BMC anesthesiology

authors： de Boer HD,Carlos RV,Brull SJ

更新日期：2018-11-06 00:00:00

abstract：BACKGROUND:The benefits of lung-protective ventilation (LPV) with a low tidal volume (6 mL/kg of ideal body weight [IBW]), limited plateau pressure (< 28-30 cm H2O), and appropriate positive end-expiratory pressure (PEEP) in patients with acute respiratory distress syndrome have become apparent and it is now widely ado...

journal_title：BMC anesthesiology

authors： Kim SH,Na S,Lee WK,Choi H,Kim J

更新日期：2018-04-02 00:00:00

abstract：BACKGROUND:The infusion of large amounts of Ringer's lactate prolongs the functional gastrointestinal recovery time and increases the number of complications after open abdominal surgery. We performed an open-labelled clinical trial to determine whether hydroxyethyl starch or Ringer's lactate exerts these adverse effec...

journal_title：BMC anesthesiology

authors： Li Y,He R,Ying X,Hahn RG

更新日期：2015-05-06 00:00:00

abstract：BACKGROUND:Abnormal acute pain after burn injury still torments patients severely. In this study, we investigated that one voltage gated sodium channel Nav1.7 plays a vital role in lowering heat pain threshold after burn injury, and the hypothesis that knockdown of Nav1.7 attenuates pain following burn injury. METHODS...

journal_title：BMC anesthesiology

authors： Cai W,Cao J,Ren X,Qiao L,Chen X,Li M,Zang W

更新日期：2016-08-11 00:00:00

abstract：BACKGROUND:Although mortality after cardiac surgery has significantly decreased in the last decade, patients still experience clinically relevant postoperative complications. Among others, atrial fibrillation (AF) is a common consequence of cardiac surgery, which is associated with prolonged hospitalization and increas...

journal_title：BMC anesthesiology

authors： Todorov H,Janssen I,Honndorf S,Bause D,Gottschalk A,Baasner S,Volkert T,Faerber V,Stover JF,Westphal M,Ellger B

更新日期：2017-12-02 00:00:00

abstract：BACKGROUND:Tracheostomy is recommended for patients receiving mechanical ventilation (MV) for 14 days or more in the intensive care unit (ICU). Nevertheless, many patients undergoing prolonged MV remain intubated via the translaryngeal route. The aim of this study was to examine the influence of tracheostomy and persis...

journal_title：BMC anesthesiology

authors： Lin WC,Chen CW,Wang JD,Tsai LM

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:Current pain assessment and treatment does not address every patient's requirements. Although the Polish national guidelines for post-operative pain management have been published, many patients experience severe pain in the postoperative period. The main goal of our study was to assess pain severity among p...

journal_title：BMC anesthesiology

authors： Borys M,Zyzak K,Hanych A,Domagała M,Gałkin P,Gałaszkiewicz K,Kłaput A,Wróblewski K,Miękina J,Onichimowski D,Czuczwar M

更新日期：2018-07-18 00:00:00

abstract：BACKGROUND:Intracranial-pressure (ICP) monitoring is useful for patients with increased ICP following hemorrhagic stroke. In this study, the changes in pressure gradients between the two cerebral hemispheres were investigated after hemorrhagic stroke of one side, and after a craniotomy. METHODS:Twenty-four patients wi...

journal_title：BMC anesthesiology

authors： Qiu W,Jiang Q,Xiao G,Wang W,Shen H

更新日期：2014-12-03 00:00:00

abstract：BACKGROUND:There are doubts among anesthesiologists on the use of the Laryngeal Mask Airway (LMA) in nasal surgeries because of concerns about the occurrence of blood leakages to the airway. We hypothesized that the use of LMA-Supreme (LMA-S) in nasal surgery is comparable with endotracheal tube (ETT) according to airw...

journal_title：BMC anesthesiology

authors： Karaaslan E,Akbas S,Ozkan AS,Colak C,Begec Z

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:To identify changes in cefoperazone/sulbactam penetration into cerebrospinal fluid (CSF) after craniotomy and to investigate preliminarily whether cefoperazone/sulbactam CSF concentration can reach therapeutic level when administered intravenously after neurosurgical operation. METHODS:Neurosurgical patient...

journal_title：BMC anesthesiology

authors： Wang Q,Wu Y,Chen B,Zhou J

更新日期：2015-03-13 00:00:00

abstract：BACKGROUND:After cesarean delivery, analgesia is often incomplete and a multimodal approach to analgesia is necessary. Transverse abdominal plane (TAP) block has been advocated in this setting, yet no systematic description of the ultrasound anatomy in pregnant women exists in the literature. Therefore, we aimed to des...

journal_title：BMC anesthesiology

authors： Kiefer N,Krahe S,Gembruch U,Weber S

更新日期：2016-12-22 00:00:00

abstract：BACKGROUND:Endotracheal extubation is the most crucial step during emergence from general anesthesia and is usually carried out when patients are awake with return of airway reflexes. Alternatively, extubations can also be accomplished while patients are deeply anesthetized, a technique known as "deep extubation", in o...

journal_title：BMC anesthesiology

authors： Juang J,Cordoba M,Ciaramella A,Xiao M,Goldfarb J,Bayter JE,Macias AA

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:Patients in intensive care units (ICUs) are often physically unable to communicate with their physicians. Thus, the sharing of information about the on-going treatment of the patients in ICUs is directly related to the communication attitudes governing a patient's relatives and the physician. This study aims...

journal_title：BMC anesthesiology

authors： Cicekci F,Duran N,Ayhan B,Arican S,Ilban O,Kara I,Turkoglu M,Yildirim F,Hasirci I,Karaibrahimoglu A,Kara I

更新日期：2017-07-17 00:00:00

abstract：BACKGROUND:The peri-operative effectiveness of ultrasound-guided great auricular nerve block (GANB) in patients, especially in adult patients undergoing middle ear microsurgery remains unclear. We hypothesized that ultrasound-guided GANB would decrease the hemodynamic responsiveness to incision and opioid consumption i...

journal_title：BMC anesthesiology

authors： Liu J,Yuan K,Zhou H,Li L,Wang G,Li T

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Sugammadex reverses neuromuscular block (NMB) through binding aminosteroid neuromuscular blocking agents. Although sugammadex appears to be highly selective, it can interact with other drugs, like corticosteroids. A prospective single-blinded randomized clinical trial was designed to explore the significance...

journal_title：BMC anesthesiology

authors： Rezonja K,Mars T,Jerin A,Kozelj G,Pozar-Lukanovic N,Sostaric M

更新日期：2016-10-21 00:00:00