Abstract:
BACKGROUND:Carbohydrate-rich liquid drinks (CRLDs) have been recommended to attenuate insulin resistance by shortening the preoperative fasting interval. The aim of our study the effect of preoperative oral administration of CRLDs on the well-being and clinical status of patients. METHODS:A randomized, double blind, prospective study of patients undergoing open colorectal operations (CR) and open cholecyctectomy (CH) was conducted. Patients were divided into three groups: study, placebo, and control. Visual analogue scale (VAS) scores for seven parameters (thirst, hunger, anxiety, mouth dryness, nausea, weakness and sleep quality) were recorded and compared for two different time periods (up to 24 h postoperatively and from 36 to 48 h postoperatively). The Simplified Acute Physiology Score changes (SAPS)-II between the three groups were also studied. RESULTS:There were 142 patients American Society of Anesthesiology (ASA) I or II enrolled in the study (CR = 71 and CH = 71). There were no significant differences in postoperative SAPS-II scores or lengths of hospital stay (LOS) between the groups. However, in CR patients, the degree of thirst was partially improved by drinking CRLDs (P = 0.027). In CH patients, on the other hand, feelings of thirst, hunger, mouth dryness, nausea and weakness showed significant improvement (P < 0.05). CONCLUSION:Oral administration of carbohydrate-rich liquid drinks (CRLDs) improves the well-being in patients undergoing CH, but the effect is less evident in patients undergoing CR. No significant improvements were seen in clinical status or in length of hospital stay in either group. TRIAL REGISTRATION:ANZCTR.org.au: ACTRN12614000995673 (registered on 16/09/2014).
journal_name
BMC Anesthesioljournal_title
BMC anesthesiologyauthors
Sada F,Krasniqi A,Hamza A,Gecaj-Gashi A,Bicaj B,Kavaja Fdoi
10.1186/1471-2253-14-93subject
Has Abstractpub_date
2014-10-17 00:00:00pages
93issn
1471-2253pii
307journal_volume
14pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Isoflurane-induced neuroapoptosis and cognitive impairment has been previously reported. Hydrogen sulfide (H2S) has been shown to be a neuromodulator that is thought to have anti-apoptotic, anti-inflammatory, and anti-oxidative benefits. However, it is not known if H2S is protective against anesthesia-induce...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-017-0419-y
更新日期:2017-09-05 00:00:00
abstract:BACKGROUND:Data on the best norepinephrine bolus dose for management of hypotension are limited. The aim of this study was to compare the efficacy and safety of two norepinephrine bolus doses in the rescue management of maternal hypotension during cesarean delivery. METHODS:This randomized, controlled trial included m...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-01004-y
更新日期:2020-04-17 00:00:00
abstract:BACKGROUND:Transpulmonary thermodilution (TPTD) derived parameters are used to direct fluid management in ICU-patients. Extravascular lung water EVLW and its ratio to pulmonary blood volume (pulmonary vascular permeability index PVPI) have been associated with mortality. In single indicator TPTD pulmonary blood volume ...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-14-81
更新日期:2014-09-24 00:00:00
abstract:BACKGROUND:Mortality from anaesthesia and surgery in many countries in Sub-Saharan Africa remain at levels last seen in high-income countries 70 years ago. With many factors contributing to these poor outcomes, the World Health Organization (WHO) launched the "Safe Surgery Saves Lives" campaign in 2007. This program in...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-016-0228-8
更新日期:2016-08-11 00:00:00
abstract:BACKGROUND:Surgical patients are asked to fast for a sufficient duration to ensure that the amount of residual liquid in the stomach is within the safe range, thereby reducing the risk of gastric reflux perioperatively. The authors hypothesized that subjective hunger numerical rating scale (NRS) score could also help a...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-018-0470-3
更新日期:2018-01-12 00:00:00
abstract:BACKGROUND:The quality of patients' recovery following surgery and anesthesia has been a matter of focus and concern over the past decade. The Quality of Recovery-40 (QoR-40) questionnaire was developed and validated for post-anesthesia patient evaluation. The QoR-40, however, is English-based and was tested and valida...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-016-0229-7
更新日期:2016-08-18 00:00:00
abstract:BACKGROUND:Abnormal acute pain after burn injury still torments patients severely. In this study, we investigated that one voltage gated sodium channel Nav1.7 plays a vital role in lowering heat pain threshold after burn injury, and the hypothesis that knockdown of Nav1.7 attenuates pain following burn injury. METHODS...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-016-0215-0
更新日期:2016-08-11 00:00:00
abstract:BACKGROUND:Pulse pressure (PPV) and stroke volume (SVV) variations may not be reliable in the setting of pulmonary hypertension and/or right ventricular (RV) failure. We hypothesized that RV afterload increase attenuates SVV and PPV during hypovolemia in a rabbit model of pulmonary embolism (PE) secondary to RV dysfunc...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-017-0329-z
更新日期:2017-03-03 00:00:00
abstract:BACKGROUND:About one third of hospital mortality in critically ill patients occurs after Intensive Care Unit (ICU) discharge. Some authors have recently hypothesized that unresolved or latent inflammation and sepsis may be an important factor that contributes to death following successful discharge from the ICU. AIM:T...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-10-17
更新日期:2010-09-27 00:00:00
abstract:BACKGROUND:Splenectomy performed with a curved incision results in severe postoperative pain. The aim of this study was to evaluate the effect of transversus abdominis plane block and rectus sheath block on postoperative pain relief and recovery. METHODS:A total of 150 patients were randomized into the control (C), le...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-020-0941-1
更新日期:2020-01-23 00:00:00
abstract:BACKGROUND:The peri-operative effectiveness of ultrasound-guided great auricular nerve block (GANB) in patients, especially in adult patients undergoing middle ear microsurgery remains unclear. We hypothesized that ultrasound-guided GANB would decrease the hemodynamic responsiveness to incision and opioid consumption i...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-01155-y
更新日期:2020-09-15 00:00:00
abstract:BACKGROUND:As defined by evidence-based medicine randomized controlled trials rank higher than observational studies in the hierarchy of clinical research. Accordingly, when assessing the effects of treatments on patient outcomes, there is a tendency to focus on the study method rather than also appraising the key elem...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-016-0264-4
更新日期:2016-10-14 00:00:00
abstract:BACKGROUND:The role of N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) as a prognostic factor in patients admitted to the intensive care unit (ICU) is not yet fully established. We aimed to determine whether NT-pro-BNP is predictive of ICU mortality in a multicenter cohort of critically ill patients. METHODS:A ...
journal_title:BMC anesthesiology
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2253-14-16
更新日期:2014-03-10 00:00:00
abstract:BACKGROUND:Ketamine and hyperoxia are widely used in obstetric and pediatric settings. Either ketamine or hyperoxia has been reported to cause neuroapoptosis in the developing brain, and ketamine-induced neuronal apoptosis may involve a compensatory upregulation of the N-methyl-D-aspartate (NMDA) receptor NR1 subunit. ...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-018-0511-y
更新日期:2018-05-10 00:00:00
abstract:BACKGROUND:Fluid overloading is detrimental to organ function and results in a poor prognosis. It is necessary to evaluate fluid responsiveness before fluid loading. We performed a systematic meta-analysis to evaluate the diagnostic value of the respiratory variation in peripheral arterial blood flow peak velocity (△Vp...
journal_title:BMC anesthesiology
pub_type: 杂志文章,meta分析
doi:10.1186/s12871-018-0635-0
更新日期:2018-11-13 00:00:00
abstract:BACKGROUND:Sevoflurane is suitable for low-flow anesthesia (LFA). LFA needs a wash-in phase. The reported sevoflurane wash-in schemes lack simplicity, target coverage, and applicability. We proposed a one-step 1-1-8 wash-in scheme for sevoflurane LFA to be used with both N2O and Air. The objective of our study was to i...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-0940-2
更新日期:2020-01-24 00:00:00
abstract:BACKGROUND:Older age is associated with chronic illnesses and disability, which contribute to increased admission to the intensive care unit (ICU). Our primary objective was to compare the characteristics, ICU management and outcomes of critically ill patients ≥ 80 year-old with those of younger patients. METHODS:This...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-14-126
更新日期:2014-12-20 00:00:00
abstract:BACKGROUND:Endotracheal tube (ETT) designs to decrease the risk of ventilator associated pneumonia (VAP) include supraglottic suctioning, and/or modifications of the cuff shape. The TaperGuard™ ETT has a tapered, polyvinylchloride cuff designed to reduce microaspiration around channels that form with a standard barrel-...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-01117-4
更新日期:2020-08-24 00:00:00
abstract:BACKGROUND:Desflurane during early reperfusion has been shown to postcondition human myocardium, in vitro. We investigated the role of adenosine and bradykinin receptors, and generation of radical oxygen species in desflurane-induced postconditioning in human myocardium. METHODS:We recorded isometric contraction of hu...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-10-12
更新日期:2010-07-29 00:00:00
abstract:BACKGROUND:Delayed gastric emptying and the resultant "full stomach" is the most important risk factor for perioperative pulmonary aspiration. Using point-of-care gastric sonography, we aimed to investigate the prevalence of full stomach and its risk factors in elective surgical patients with type 2 diabetes. METHODS:...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-019-0848-x
更新日期:2019-10-10 00:00:00
abstract:BACKGROUND:Sugammadex reverses neuromuscular block (NMB) through binding aminosteroid neuromuscular blocking agents. Although sugammadex appears to be highly selective, it can interact with other drugs, like corticosteroids. A prospective single-blinded randomized clinical trial was designed to explore the significance...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-016-0254-6
更新日期:2016-10-21 00:00:00
abstract:BACKGROUND:In infants, securing the airway is time-critical because of anatomical and physiological differences related to airway management in children less than 1 year old. The aim of this study was to compare the time to ventilation using two different hyperangulated video laryngoscope blades with the time to ventil...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-018-0580-y
更新日期:2018-08-31 00:00:00
abstract:BACKGROUND:Conventionally, ultrasonographic assessment of diaphragm contractility has involved measuring respiratory changes in diaphragm thickness (thickening fraction) using B-mode or caudal displacement with M-mode. Two-dimensional speckle-tracking has been increasingly used to assess muscle deformation ('strain') i...
journal_title:BMC anesthesiology
pub_type: 临床试验,杂志文章
doi:10.1186/s12871-016-0201-6
更新日期:2016-07-25 00:00:00
abstract:BACKGROUND:Even the best cancer surgery is usually associated with minimal residual disease. Whether these remaining malignant cells develop into clinical recurrence is at least partially determined by adequacy of host defense, especially natural killer cell function. Anesthetics impair immune defenses to varying degre...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-9-1
更新日期:2009-02-03 00:00:00
abstract:BACKGROUND:Tracheostomy is recommended for patients receiving mechanical ventilation (MV) for 14 days or more in the intensive care unit (ICU). Nevertheless, many patients undergoing prolonged MV remain intubated via the translaryngeal route. The aim of this study was to examine the influence of tracheostomy and persis...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-015-0159-9
更新日期:2015-12-15 00:00:00
abstract:BACKGROUND:Abnormal laryngeal structures are likely to be associated with a difficult laryngoscopy procedure. Currently, laryngeal structures can be measured by ultrasonography, however, little research has been performed on the potential role of ultrasound on the evaluation of a difficult laryngoscopy. The present stu...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-01053-3
更新日期:2020-06-02 00:00:00
abstract:BACKGROUND:A mouth gag is usually used during tonsillectomy and adenotonsillectomy surgeries, cleft palate repair, obstructive sleep apnea surgery, and intraoral tumor excision. The placement of the gag causes hemodynamic changes similar to laryngoscopy. The aim of this study was to evaluate the effect of mouth gag pla...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-01079-7
更新日期:2020-07-03 00:00:00
abstract:BACKGROUND:Perioperative immune function plays an important role in the prognosis of patients. Several studies have indicated that low-dose opioid receptor blockers can improve immune function. METHODS:Sixty-nine patients undergoing video-assisted thoracoscopic resection of the lung cancer were randomly assigned to ei...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-019-0912-6
更新日期:2019-12-19 00:00:00
abstract:BACKGROUND:Although mortality after cardiac surgery has significantly decreased in the last decade, patients still experience clinically relevant postoperative complications. Among others, atrial fibrillation (AF) is a common consequence of cardiac surgery, which is associated with prolonged hospitalization and increas...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-017-0455-7
更新日期:2017-12-02 00:00:00
abstract:BACKGROUND:Mismanagement of remifentanil leads to severe side effects such as opioid-induced tolerance and hyperalgesia. Recently studies revealed an alternative withdrawal method to limit these side effects. A gradual withdrawal of remifentanil seems to be associated with less pain. The hypothesis of this double-blind...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-019-0731-9
更新日期:2019-04-25 00:00:00