Abstract：
:BACKGROUND: We report a case of a patient with apparent resistance to local anesthetics. While similar cases of failure of regional anesthetics are often attributed to technical failure, the overall clinical presentation and history of this patient suggests a true resistance to local anesthetics. CASE PRESENTATION: This patient presented for elective cesarean section and the decision for regional anesthesia was made. While attempting to place an epidural, the patient failed to achieve adequate skin analgesia despite multiple attempts at local infiltration. When a spinal was ultimately placed, sensory or motor blockade was not obtained despite no evidence of technical problems with technique. Further questioning revealed multiple prior episodes of local anesthetic failure in this patient. CONCLUSIONS: While the failure rate of spinal anesthesia has been shown range from 4-13% and is often attributed to technical failure, elements of this particular case suggest a true resistance to local anesthetics.
journal_name
BMC Anesthesioljournal_title
BMC anesthesiologyauthors
Kavlock R,Ting PHdoi
10.1186/1471-2253-4-1keywords:
subject
Has Abstractpub_date
2004-01-16 00:00:00pages
1issue
1issn
1471-2253pii
1471-2253-4-1journal_volume
4pub_type
杂志文章abstract：BACKGROUND:There is no defined gold standard for pain management after video-assisted thoracic surgery (VATS) for pneumothorax. In addition to systemic analgesia, various loco-regional analgesic techniques have been proposed but remain poorly evaluated in this context. We aimed to assess the analgesic efficacy of sever...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-019-0797-4
更新日期：2019-07-06 00:00:00
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journal_title：BMC anesthesiology
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pub_type： 临床试验,杂志文章
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journal_title：BMC anesthesiology
pub_type： 杂志文章,多中心研究,随机对照试验
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journal_title：BMC anesthesiology
pub_type： 杂志文章,meta分析
doi：10.1186/s12871-018-0635-0
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pub_type： 杂志文章,随机对照试验
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更新日期：2017-04-27 00:00:00
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journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-018-0495-7
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更新日期：2015-03-08 00:00:00
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doi：10.1186/1471-2253-14-52
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pub_type： 杂志文章,随机对照试验
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更新日期：2016-07-30 00:00:00
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journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/1471-2253-7-6
更新日期：2007-07-07 00:00:00
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pub_type： 杂志文章,随机对照试验
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更新日期：2020-01-30 00:00:00
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pub_type： 杂志文章,评审
doi：10.1186/s12871-018-0605-6
更新日期：2018-11-06 00:00:00
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pub_type： 杂志文章
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journal_title：BMC anesthesiology
pub_type： 杂志文章,随机对照试验
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更新日期：2014-12-10 00:00:00
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pub_type： 杂志文章
doi：10.1186/s12871-016-0289-8
更新日期：2016-12-22 00:00:00
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pub_type： 杂志文章,随机对照试验
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