Abstract：
BACKGROUND:Effectiveness of the donation request is generally measured by consent rates, rather than by relatives' satisfaction with their decision. Our aim was to elicit Dutch ICU staffs' views and experiences with the donation request, to investigate their awareness of (dis)satisfaction with donation decisions by relatives, specifically in the case of refusal, and to collect advice that may leave more relatives satisfied with their decision. METHODS:Five focus groups with a total of 32 participants (IC physicians, IC nurses and transplant coordinators) from five university hospitals in the Netherlands. Transcripts were examined using standard qualitative methods. RESULTS:Four themes (donation request perceived by ICU staff from the perspective of relatives; donation request perceived by ICU staff from their own perspective; aftercare; donation in society) divided into 14 categories were identified. According to ICU staff, relatives mentioned their own values more frequently than values of the potential donor as important for the decision. ICU staff observed this imbalance, but reacted empathically to the relatives' point of view. ICU staff rarely suggested reconsideration of refusal and did not ask relatives for arguments. ICU staff did not always feel comfortable with a request in the delicate context of brain death. Sometimes the interests of patient, relatives and those on the waiting list were irreconcilable. ICU staff were mostly unaware of relatives' regret following their decisions. Aftercare did not provide this type of information. Donation request by IC physicians was influenced by the way organ donation has been regulated in society (law, donor register, education, media). CONCLUSIONS:Our findings lead to the hypothesis that giving relatives more time and inviting them to reconsider their initial refusal will lead to a more stable decision and possibly more consent.
journal_name
BMC Anesthesioljournal_title
BMC anesthesiologyauthors
de Groot J,Vernooij-Dassen M,de Vries A,Hoedemaekers C,Hoitsma A,Smeets W,van Leeuwen Edoi
10.1186/1471-2253-14-52subject
Has Abstractpub_date
2014-07-11 00:00:00pages
52issn
1471-2253pii
1471-2253-14-52journal_volume
14pub_type
杂志文章abstract：BACKGROUND:McGrath MAC video laryngoscope offers excellent laryngosopic views and increases the success rate of orotracheal intubation in some cases. The aim of this study was to determine the usefulness of McGrath MAC for routine nasotracheal intubation by comparing McGrath MAC with Airway scope and Macintosh laryngos...
journal_title：BMC anesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12871-017-0451-y
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Fentanyl and remifentanil are widely used opioids in surgery, but it has not been evaluated whether the choice of opioids during surgery affects the patients' postoperative quality of recovery. Accordingly, we aim to compare postoperative recovery of fentanyl-based anesthesia with remifentanil-based anesthes...
journal_title：BMC anesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12871-018-0547-z
更新日期：2018-07-11 00:00:00
abstract：BACKGROUND:Local anesthetic Bupivacaine commonly used in gastric cancer resection operation has been reported to suppress the progression of gastric cancer. However, the specific mechanism by which Bupivacaine functions is largely unexplored. METHODS:The viability and metastasis of gastric cancer cells were assessed b...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-020-01179-4
更新日期：2020-10-30 00:00:00
abstract：BACKGROUND:The present anonymous multicenter online survey was conducted to evaluate the application of regional anaesthesia techniques as well as the used local anaesthetics and adjuncts at German and Austrian university hospitals. METHODS:39 university hospitals were requested to fill in an online questionnaire, to ...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/1471-2253-10-4
更新日期：2010-04-17 00:00:00
abstract：BACKGROUND:The effect of adding clonidine to local anesthetics for nerve or plexus blocks remains unclear. Most of the studies in adults have demonstrated the positive effects of clonidine on intra- and postoperative analgesia when used as an adjunctive agent or in some cases as a single to regional techniques. In the ...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/1471-2253-12-2
更新日期：2012-02-01 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via the original article. ...
journal_title：BMC anesthesiology
pub_type： 已发布勘误
doi：10.1186/s12871-020-01196-3
更新日期：2020-11-09 00:00:00
abstract：BACKGROUND:The timing of laryngeal mask airway (LMA) removal remains undefined. This study aimed to assess the optimal timing for LMA removal and whether topical anesthesia with lidocaine could reduce airway adverse events. METHODS:This randomized controlled trial assessed one-to-six-year-old children with ASA I-II sc...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-021-01235-7
更新日期：2021-01-08 00:00:00
abstract：BACKGROUND:The benefits of lung-protective ventilation (LPV) with a low tidal volume (6 mL/kg of ideal body weight [IBW]), limited plateau pressure (< 28-30 cm H2O), and appropriate positive end-expiratory pressure (PEEP) in patients with acute respiratory distress syndrome have become apparent and it is now widely ado...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-018-0495-7
更新日期：2018-04-02 00:00:00
abstract：BACKGROUND:General anesthesia has been linked to impaired brain development in immature animals and young children. In this study the influence of orthopedic surgery under general anesthesia on the intelligence of school age children has been evaluated. METHODS:A total of 209 subjects aged 6-12 years were recruited an...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-017-0462-8
更新日期：2017-12-19 00:00:00
abstract：BACKGROUND:Low-flow sevoflurane anesthesia has been shown to influence renal function in rats, but not in adult humans. Presently, no study has assessed the effects of sevoflurane on renal function in low birth weight infants. Our aim was to study the renal function in low birth weight infants undergoing surgery with l...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/1471-2253-15-6
更新日期：2015-01-21 00:00:00
abstract：BACKGROUND:Tramadol is an atypical centrally acting analgesic agent available as both oral and parenteral preparations. For patients who are unable to take tramadol orally, the subcutaneous route of administration offers an easy alternative to intravenous or intramuscular routes. This study aimed to characterise the ab...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/1471-2253-14-33
更新日期：2014-05-12 00:00:00
abstract：BACKGROUND:Performing spinal anaesthesia using the conventional popping method with a 27-gauge (27G) spinal needle is technically difficult. In this study, we compared the aspiration and conventional popping method for spinal anaesthesia using 27G Quincke-type needles. METHODS:This prospective, randomized study enroll...
journal_title：BMC anesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12871-020-0954-9
更新日期：2020-01-30 00:00:00
abstract：BACKGROUND:Preoperative intravenous rehydration for patients with pheochromocytomas and paragangliomas (PPGLs) is widely used in many medical centers, but its usefulness has not been well evaluated. The objective of this study was to compare the perioperative hemodynamics and early outcome between patients who received...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-020-01212-6
更新日期：2020-11-30 00:00:00
abstract：BACKGROUND:Sodium nitroprusside (SNP) is a potent vasodilator that has been used to induce deliberate hypotension in children during surgery involving significant blood loss, including craniofacial and spinal fusion procedures. SNP metabolism liberates cyanide, which may cause interference with cellular energy metaboli...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/1471-2253-13-9
更新日期：2013-04-30 00:00:00
abstract：BACKGROUND:Fluid overloading is detrimental to organ function and results in a poor prognosis. It is necessary to evaluate fluid responsiveness before fluid loading. We performed a systematic meta-analysis to evaluate the diagnostic value of the respiratory variation in peripheral arterial blood flow peak velocity (△Vp...
journal_title：BMC anesthesiology
pub_type： 杂志文章,meta分析
doi：10.1186/s12871-018-0635-0
更新日期：2018-11-13 00:00:00
abstract：BACKGROUND:After cesarean delivery, analgesia is often incomplete and a multimodal approach to analgesia is necessary. Transverse abdominal plane (TAP) block has been advocated in this setting, yet no systematic description of the ultrasound anatomy in pregnant women exists in the literature. Therefore, we aimed to des...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-016-0289-8
更新日期：2016-12-22 00:00:00
abstract：BACKGROUND:Mismanagement of remifentanil leads to severe side effects such as opioid-induced tolerance and hyperalgesia. Recently studies revealed an alternative withdrawal method to limit these side effects. A gradual withdrawal of remifentanil seems to be associated with less pain. The hypothesis of this double-blind...
journal_title：BMC anesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12871-019-0731-9
更新日期：2019-04-25 00:00:00
abstract：BACKGROUND:We sought to evaluate the effect of mild hypercapnia on brain tissue oxygen tension (Pbto2) and diffusion limitation (impaired ability of oxygen extraction) in a porcine post asphyxial cardiac arrest model. METHODS:In 16 Bama pigs, asphyxial cardiac arrest was induced by endotracheal tube clamping and remai...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-020-01162-z
更新日期：2020-09-29 00:00:00
abstract：BACKGROUND:In patients with subarachnoid hemorrhage (SAH), vasospasm remains one of the major complications. The application of intravenous magnesium sulfate (MgSO4) has been under discussion to prevent cerebral ischemia. Our aim was to examine the impact of early MgSO4 administration on local cerebral microcirculation...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-017-0435-y
更新日期：2017-10-17 00:00:00
abstract：BACKGROUND:Early aggressive therapy can reduce the mortality associated with severe sepsis but this relies on prompt recognition, which is hindered by variation among published severity criteria. Our aim was to test the performance of different severity scores in predicting mortality among a cohort of hospital inpatien...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/1471-2253-14-1
更新日期：2014-01-02 00:00:00
abstract：BACKGROUND:The frequency of malpositioning of gastric tubes in the trachea has been reported to be 0.3-15%, which may cause severe complications, such as pneumonia, if not detected promptly. If a gastric tube can be guided into the esophagus under direct vision with a video laryngoscope, misplacement of the gastric tub...
journal_title：BMC anesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1186/1471-2253-14-82
更新日期：2014-09-25 00:00:00
abstract：BACKGROUND:Endotracheal intubation of patients with massive regurgitation represents a challenge in emergency airway management. Gastric contents tend to block suction catheters, and few treatment alternatives exist. Based on a technique that was successfully applied in our district, we wanted to examine if endotrachea...
journal_title：BMC anesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12871-018-0474-z
更新日期：2018-01-18 00:00:00
abstract：BACKGROUND:Isoflurane-induced neuroapoptosis and cognitive impairment has been previously reported. Hydrogen sulfide (H2S) has been shown to be a neuromodulator that is thought to have anti-apoptotic, anti-inflammatory, and anti-oxidative benefits. However, it is not known if H2S is protective against anesthesia-induce...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-017-0419-y
更新日期：2017-09-05 00:00:00
abstract：BACKGROUND:Children require anesthesia for MRI to maintain immobility and reduce discomfort; clear indications about the best anesthesiologic management are lacking and each center developed its own protocol. Moreover, children with neuropsychiatric disorders more likely require sedation and are described in literature...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-019-0897-1
更新日期：2019-12-18 00:00:00
abstract：BACKGROUND:Increase of pulmonary vascular resistance (PVR) is an efficient method of modulating pulmonary and systemic blood flows (Qp/Qs) for patients with left-to-right (L-R) shunt, and is also closely associated with insufficient oxygen exchange for pulmonary hypoperfusion. So that it might be a preferred regime of ...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-019-0852-1
更新日期：2019-10-09 00:00:00
abstract：BACKGROUND:The passive ventilation of nonventilated lung results in tidal gas movement (TGM) and thus affects lung collapse. The present study aimed to measure the volume of TGM and to analyse the relevant factors of the TGM index (TGM/body surface area). METHODS:One hundred eight patients scheduled for elective thora...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-020-0937-x
更新日期：2020-01-22 00:00:00
abstract：BACKGROUND:The volatile anesthetic isoflurane protects the heart from hypoxia/reperfusion (H/R) injury. However, it is still incompletely understood whether isoflurane exerts its protective role through preventing mitochondrial permeability transition pore (MPTP) opening. METHODS:Primary cultured cardiocytes were expo...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/1471-2253-14-17
更新日期：2014-03-10 00:00:00
abstract：BACKGROUND:Persistently variable success has been experienced in locally translating even well-grounded national clinical practice guidelines, including in the perioperative setting. We have sought greater applicability and acceptance of clinical practice guidelines and protocols with our novel Perioperative Risk Optim...
journal_title：BMC anesthesiology
pub_type： 杂志文章
doi：10.1186/s12871-016-0187-0
更新日期：2016-03-22 00:00:00
abstract：BACKGROUND:To determine whether continuous intravenous infusion of dexmedetomidine (DEX) can affect the incidence of Emergence Agitation (EA) after general anesthesia in infant undergoing cleft palate repair surgery. METHODS:Forty infants underwent cleft palate repair surgery under general anesthesia were randomly div...
journal_title：BMC anesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12871-015-0124-7
更新日期：2015-10-13 00:00:00
abstract：BACKGROUND:Perioperative hemodynamic fluctuations are seen more often in hypertensive patients than in normotensive patients. The purpose of our study was to investigate the perioperative hemodynamic effects of dexmedetomidine and midazolam used for premedication in hypertensive patients relative to each other and in c...
journal_title：BMC anesthesiology
pub_type： 杂志文章,随机对照试验
doi：10.1186/1471-2253-14-113
更新日期：2014-12-10 00:00:00
