当前位置： SCI文献检索 > BMC Anesthesiology期刊下所有文献 > Effect of ketofol versus propofol as an induction agent on ease of laryngeal mask airway insertion conditions and hemodynamic stability in pediatrics: an observational prospective cohort study.

Effect of ketofol versus propofol as an induction agent on ease of laryngeal mask airway insertion conditions and hemodynamic stability in pediatrics: an observational prospective cohort study.

Abstract：

BACKGROUND:Laryngeal mask airway is a supraglottic airway device which has led to a fundamental change in the management of modern general anesthesia. In the present study; we evaluated the laryngeal mask airway insertion conditions and hemodynamic changes comparing ketamine-propofol mixture (ketofol) with propofol. The study was to compare the ketamine-propofol mixture (ketofol) with propofolon the ease of laryngeal mask airway insertion conditions and hemodynamic effects for induction of general anesthesia. METHODS:One hundred twenty pediatric patients were recruited and assigned to two groups (60 each). Group KP = ketofol, group P = propofol. Insertion conditions were compared using a Chi-square test while hemodynamic variables were compared using the independentt-test. Statistical significance was stated at p-value< 0.05. RESULTS:Laryngeal mask airway insertion summed score was nearly similar between the two groups. Mean blood pressure and heart rate were maintained higher in ketofol group while a significant drop was observed in the propofol group. The time from the Laryngeal mask airway placement to the return of spontaneous ventilation was significantly longer in propofol group (240 s [range = 60-360 s]) compared with ketofol group (180 s [range = 30-320 s]) (p = 0.005). CONCLUSIONS:Laryngeal mask airway insertion condition summed score was comparable in both ketofol and propofol group. Ketofol provided equivalent laryngeal mask airway insertion conditions while maximizing hemodynamics and minimizing apnea time. Ketofol can be used as an alternative to propofol for laryngeal mask airway insertion in pediatrics.

journal_name

BMC Anesthesiol

journal_title

BMC anesthesiology

authors

Aberra B,Aregawi A,Teklay G,Tasew H

doi

10.1186/s12871-019-0711-0

subject

Has Abstract

pub_date

2019-03-20 00:00:00

pages

41

issue

1

issn

1471-2253

pii

10.1186/s12871-019-0711-0

journal_volume

19

pub_type

杂志文章

相关文献

BMC Anesthesiology文献大全