In vitro effects of levosimendan on muscle of malignant hyperthermia susceptible and non-susceptible swine.

abstract：BACKGROUND:Ketamine and hyperoxia are widely used in obstetric and pediatric settings. Either ketamine or hyperoxia has been reported to cause neuroapoptosis in the developing brain, and ketamine-induced neuronal apoptosis may involve a compensatory upregulation of the N-methyl-D-aspartate (NMDA) receptor NR1 subunit. ...

journal_title：BMC anesthesiology

authors： Wu C,Wang J,Guo X,Zhang Y

更新日期：2018-05-10 00:00:00

abstract：BACKGROUND:Neuropathic pain is evasive to treat once developed, however evidence suggests that local administration of anesthetics near the time of injury reduces the development of neuropathic pain. As abnormal electrical signaling in the damaged nerve contributes to the initiation and maintenance of neuropathic pain,...

journal_title：BMC anesthesiology

authors： Clifford JL,Mares A,Hansen J,Averitt DL

更新日期：2015-10-06 00:00:00

abstract：BACKGROUND:Sugammadex is a modified gamma-cyclodextrin that acts by selectively encapsulating free amino-steroidal neuromuscular relaxants. Several case reports have been published on the use of sugammadex in patients with neuromuscular disorders that include neuromuscular junction diseases, myopathies, neuropathies, a...

journal_title：BMC anesthesiology

authors： Gurunathan U,Kunju SM,Stanton LML

更新日期：2019-11-19 00:00:00

abstract：BACKGROUND:Mismanagement of remifentanil leads to severe side effects such as opioid-induced tolerance and hyperalgesia. Recently studies revealed an alternative withdrawal method to limit these side effects. A gradual withdrawal of remifentanil seems to be associated with less pain. The hypothesis of this double-blind...

journal_title：BMC anesthesiology

authors： Saxena S,Gonsette K,Terram W,Huybrechts I,Nahrwold DA,Cappello M,Barvais L,Engelman E

更新日期：2019-04-25 00:00:00

abstract：BACKGROUND:Ultrasound gels may contain propylene glycol and glycerol, which are neurotoxic in high concentrations. If the needle passes through gel during regional anesthesia, gel may be injected near the nerve. It is unknown if this practice poses a risk for neurotoxicity. Using an animal model, we assessed the histol...

journal_title：BMC anesthesiology

authors： Belavy D,Sunn N,Lau Q,Robertson T

更新日期：2013-09-03 00:00:00

abstract：BACKGROUND:Sugammadex reverses neuromuscular block (NMB) through binding aminosteroid neuromuscular blocking agents. Although sugammadex appears to be highly selective, it can interact with other drugs, like corticosteroids. A prospective single-blinded randomized clinical trial was designed to explore the significance...

journal_title：BMC anesthesiology

authors： Rezonja K,Mars T,Jerin A,Kozelj G,Pozar-Lukanovic N,Sostaric M

更新日期：2016-10-21 00:00:00

abstract：BACKGROUND:In patients with subarachnoid hemorrhage (SAH), vasospasm remains one of the major complications. The application of intravenous magnesium sulfate (MgSO4) has been under discussion to prevent cerebral ischemia. Our aim was to examine the impact of early MgSO4 administration on local cerebral microcirculation...

journal_title：BMC anesthesiology

authors： Sommer B,Weidinger CS,Wolf D,Buchfelder M,Schmitt H

更新日期：2017-10-17 00:00:00

abstract：BACKGROUND:Preoperative intravenous rehydration for patients with pheochromocytomas and paragangliomas (PPGLs) is widely used in many medical centers, but its usefulness has not been well evaluated. The objective of this study was to compare the perioperative hemodynamics and early outcome between patients who received...

journal_title：BMC anesthesiology

authors： Kong H,Yang JN,Tian J,Li N,Zhang YX,Ye PC,Li XY,Zhang Z

更新日期：2020-11-30 00:00:00

abstract：BACKGROUND:In what way volume, concentration and dose affect block duration is controversial. The purpose of the present study is to investigate the effect of dose, volume and concentration of mepivacaine on the duration of sensory and motor blockade in ultrasound-guided single shot axillary brachial plexus blockade. ...

journal_title：BMC anesthesiology

authors： Fenten MG,Schoenmakers KP,Heesterbeek PJ,Scheffer GJ,Stienstra R

更新日期：2015-09-30 00:00:00

abstract：BACKGROUND:Local anesthesia can reduce the response to surgical stress and decrease the consumption of opioids, which may reduce immunosuppression and potentially delay postoperative tumor recurrence. We compared paravertebral block (PVB) combined with general anesthesia (GA) and general anesthesia regarding their effe...

journal_title：BMC anesthesiology

authors： Chu H,Dong H,Wang Y,Niu Z

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:The frequency of malpositioning of gastric tubes in the trachea has been reported to be 0.3-15%, which may cause severe complications, such as pneumonia, if not detected promptly. If a gastric tube can be guided into the esophagus under direct vision with a video laryngoscope, misplacement of the gastric tub...

journal_title：BMC anesthesiology

authors： Okabe T,Goto G,Hori Y,Sakamoto A

更新日期：2014-09-25 00:00:00

abstract：BACKGROUND:Embolic stroke is a common complication of atrial myxoma, whereas multiple cerebral aneurysms associated with atrial myxoma is rare. The pathogenesis of the cerebral vascular disease related to an atrial myxoma is still not well known, and there are no guidelines to guide treatment and anesthesia management ...

journal_title：BMC anesthesiology

authors： Zhang R,Tang Z,Qiao Q,Mahmood F,Feng Y

更新日期：2020-07-04 00:00:00

abstract：BACKGROUND:Early aggressive therapy can reduce the mortality associated with severe sepsis but this relies on prompt recognition, which is hindered by variation among published severity criteria. Our aim was to test the performance of different severity scores in predicting mortality among a cohort of hospital inpatien...

journal_title：BMC anesthesiology

authors： Marwick CA,Guthrie B,Pringle JE,McLeod SR,Evans JM,Davey PG

更新日期：2014-01-02 00:00:00

abstract：BACKGROUND:Gabapentin is an antiepileptic drug used in a variety of chronic pain conditions. Increasing numbers of randomized trials indicate that gabapentin is effective as a postoperative analgesic. This procedure-specific systematic review aims to analyse the 24-hour postoperative effect of gabapentin on acute pain ...

journal_title：BMC anesthesiology

authors： Mathiesen O,Møiniche S,Dahl JB

更新日期：2007-07-07 00:00:00

abstract：BACKGROUND:Children require anesthesia for MRI to maintain immobility and reduce discomfort; clear indications about the best anesthesiologic management are lacking and each center developed its own protocol. Moreover, children with neuropsychiatric disorders more likely require sedation and are described in literature...

journal_title：BMC anesthesiology

authors： Mongodi S,Ottonello G,Viggiano R,Borrelli P,Orcesi S,Pichiecchio A,Balottin U,Mojoli F,Iotti GA

更新日期：2019-12-18 00:00:00

abstract：BACKGROUND:The benefits of lung-protective ventilation (LPV) with a low tidal volume (6 mL/kg of ideal body weight [IBW]), limited plateau pressure (< 28-30 cm H2O), and appropriate positive end-expiratory pressure (PEEP) in patients with acute respiratory distress syndrome have become apparent and it is now widely ado...

journal_title：BMC anesthesiology

authors： Kim SH,Na S,Lee WK,Choi H,Kim J

更新日期：2018-04-02 00:00:00

abstract：BACKGROUND:Low-flow sevoflurane anesthesia has been shown to influence renal function in rats, but not in adult humans. Presently, no study has assessed the effects of sevoflurane on renal function in low birth weight infants. Our aim was to study the renal function in low birth weight infants undergoing surgery with l...

journal_title：BMC anesthesiology

authors： Xing N,Wei X,Chang Y,Du Y,Zhang W

更新日期：2015-01-21 00:00:00

abstract：BACKGROUND:The primary goal of this study was to determine whether administration of intrathecal morphine reduces postoperative pain. The secondary goal was to determine the effect of intrathecal morphine upon circulating levels of the weakly analgesic endocannabinoids, anandamide (AEA) and 2-arachidonoylglycerol (2-AG...

journal_title：BMC anesthesiology

authors： Kaczocha M,Azim S,Nicholson J,Rebecchi MJ,Lu Y,Feng T,Romeiser JL,Reinsel R,Rizwan S,Shodhan S,Volkow ND,Benveniste H

更新日期：2018-02-27 00:00:00

abstract：BACKGROUND:Since blood pressure tends to be unstable during induction of anesthesia in patients undergoing cardiovascular surgery, an artery catheter is often inserted before induction to continuously monitor arterial pressure during induction of anesthesia. ClearSight System™ enables noninvasive continuous measurement...

journal_title：BMC anesthesiology

authors： Tanioku T,Yoshida A,Aratani Y,Fujii K,Kawamata T

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:To assess the effect of rostral anterior cingulate cortex (rACC) administration with ifenprodil (NR2B receptor blocker) on bone cancer pain (BCP)-related aversion sentiment using the conditioned place avoidance experiments in rats. METHODS:A total of 30 male Wistar rats without place preference were randoml...

journal_title：BMC anesthesiology

authors： Feng H,Chen Z,Wang G,Zhao X,Liu Z

更新日期：2016-11-21 00:00:00

abstract：BACKGROUND:As defined by evidence-based medicine randomized controlled trials rank higher than observational studies in the hierarchy of clinical research. Accordingly, when assessing the effects of treatments on patient outcomes, there is a tendency to focus on the study method rather than also appraising the key elem...

journal_title：BMC anesthesiology

authors： Trentino K,Farmer S,Gross I,Shander A,Isbister J

更新日期：2016-10-14 00:00:00

abstract：BACKGROUND:Hyperthermic isolated limb perfusion (HILP) is used for patients with intractable or extensive in-transit metastatic melanoma of the limb to deliver high concentrations of cytotoxic agents to the affected limb and offers a treatment option in a disease stage with a poor prognosis when no treatment is given. ...

journal_title：BMC anesthesiology

authors： Ruschulte H,Shi S,Tseng WW,Kolodzie K,Crawford PC,Schneider DB,Kashani-Sabet M,Minor D,Apfel C,Leong SP

更新日期：2013-07-17 00:00:00

abstract：BACKGROUND:There are doubts among anesthesiologists on the use of the Laryngeal Mask Airway (LMA) in nasal surgeries because of concerns about the occurrence of blood leakages to the airway. We hypothesized that the use of LMA-Supreme (LMA-S) in nasal surgery is comparable with endotracheal tube (ETT) according to airw...

journal_title：BMC anesthesiology

authors： Karaaslan E,Akbas S,Ozkan AS,Colak C,Begec Z

更新日期：2021-01-07 00:00:00

abstract：:We have developed a two-step procedure for preparing the skin before peripheral venous catheter (PVC) insertions. This procedure involves two successive swabbings with wipes soaked in alcoholic antiseptic. We investigated whether this two-step procedure was as effective and safe as the standard four-step procedure--wa...

journal_title：BMC anesthesiology

authors： van der Mee-Marquet NL,Bloodstream infection Study Group of the Relais Régional d'Hygiène Hospitalière du Centre.

更新日期：2007-01-31 00:00:00

abstract：BACKGROUND:Preoperative oral carbohydrates has been suggested to attenuate insulin resistance and decrease postoperative complications. In this study, a vitamin-rich carbohydrate beverage was administered before surgery in an animal model to investigate its effects on the surgical stress response and S-100β levels. ME...

journal_title：BMC anesthesiology

authors： Zuo Y,Zhao L,Zeng M,Yang Q,Chen X,Yang T

更新日期：2019-05-15 00:00:00

abstract：BACKGROUND:The peri-operative effectiveness of ultrasound-guided great auricular nerve block (GANB) in patients, especially in adult patients undergoing middle ear microsurgery remains unclear. We hypothesized that ultrasound-guided GANB would decrease the hemodynamic responsiveness to incision and opioid consumption i...

journal_title：BMC anesthesiology

authors： Liu J,Yuan K,Zhou H,Li L,Wang G,Li T

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Fentanyl and remifentanil are widely used opioids in surgery, but it has not been evaluated whether the choice of opioids during surgery affects the patients' postoperative quality of recovery. Accordingly, we aim to compare postoperative recovery of fentanyl-based anesthesia with remifentanil-based anesthes...

journal_title：BMC anesthesiology

authors： Asakura A,Mihara T,Goto T

更新日期：2018-07-11 00:00:00

abstract：BACKGROUND:Performing spinal anaesthesia using the conventional popping method with a 27-gauge (27G) spinal needle is technically difficult. In this study, we compared the aspiration and conventional popping method for spinal anaesthesia using 27G Quincke-type needles. METHODS:This prospective, randomized study enroll...

journal_title：BMC anesthesiology

authors： Han JU,Kim BG,Yang C,Choi WH,Jeong J,Lee KJ,Kim H

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:Renal dysfunction following intraoperative arterial hypotension is mainly caused by an insufficient renal blood flow. It is associated with higher mortality and morbidity rates. We hypothesised that the intraoperative haemodynamics are more stable during xenon anaesthesia than during isoflurane anaesthesia i...

journal_title：BMC anesthesiology

authors： Schäfer P,Fahlenkamp A,Rossaint R,Coburn M,Kowark A

更新日期：2019-07-09 00:00:00

abstract：BACKGROUND:Knee arthroplasty leads to postoperative pain. This study compares analgesia and postoperative bleeding achieved by intrathecal morphine with a continuous femoral plus single-shot sciatic nerve block. METHODS:A randomized non-blinded clinical trial enrolled patients aged over 18 years old, ASA I to III who ...

journal_title：BMC anesthesiology

authors： Álvarez NER,Ledesma RJG,Hamaji A,Hamaji MWM,Vieira JE

更新日期：2017-05-12 00:00:00