Abstract:
BACKGROUND:Breast cancer surgery is one of the most common surgeries among the female population. Nearly half of the patients suffer chronic pain following breast cancer surgery, and 24% of them categorizing their pain as moderate to high. In this study, effects of ultrasound-guided erector spinae plane (ESP) block performed using two different concentrations of bupivacaine on postoperative tramadol consumption, pain scores, and intraoperative fentanyl requirements among patients who underwent radical mastectomy surgery were compared. METHODS:This double-blinded, prospective, and randomized study included patients with age ranged 18-70, American Society of Anesthesiologist physical status I-II, and scheduled for unilateral modified radical mastectomy surgery. The patients were randomly allocated into two groups. In group I, ESP block was performed with 0.375% bupivacaine. In group II, ESP block was performed with 0.25% bupivacaine. General anesthesia was induced in both groups according to the standard procedures. When the pain score was ≥4, patients received intravenous (i.v.) 25 mcg fentanyl in the recovery room or 4 mg of morphine in the surgical ward as a rescue analgesia. The main measurements were postoperative tramadol consumption; Numerical Rating Scale (NRS) scores 15, 30, and 60 min and 12 and 24 h postoperatively; and intraoperative fentanyl requirements. RESULTS:In total, 42 patients (21 patients in each group) were included in the study. The mean tramadol consumption at the postoperative 24th h was 149.52 ± 25.39 mg in group I, and 199.52 ± 32.78 mg in group II (p = 0.001). In group I, the NRS scores were significantly lower at every time points compared with those in group II. The mean intraoperative fentanyl requirement was similar in the two groups. CONCLUSION:Although ESP block performed with both concentrations of bupivacaine provided effective postoperative analgesia, the higher concentration of bupivacaine significantly reduced postoperative tramadol consumption after radical mastectomy surgery. CLINICAL TRIAL REGISTRATION:The study was registered prospectively with the Australian New Zealand Clinical Trials Registry (trial ID: ACTRN12618001334291at 08/08/2018).
journal_name
BMC Anesthesioljournal_title
BMC anesthesiologyauthors
Altıparmak B,Korkmaz Toker M,Uysal Aİ,Gümüş Demirbilek Sdoi
10.1186/s12871-019-0700-3subject
Has Abstractpub_date
2019-03-04 00:00:00pages
31issue
1issn
1471-2253pii
10.1186/s12871-019-0700-3journal_volume
19pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Obstetric dfficult airway is a leading cause of maternal morbidity and mortality. The laryngeal mask airway (LMA) is often used as a rescue airway device after failed intubation, however, little is known about predictors of difficult LMA insertion, particularly in obstetrics. Since Mallampati scores of III/I...
journal_title:BMC anesthesiology
pub_type: 临床试验,杂志文章
doi:10.1186/s12871-019-0796-5
更新日期:2019-07-08 00:00:00
abstract:BACKGROUND:About one third of hospital mortality in critically ill patients occurs after Intensive Care Unit (ICU) discharge. Some authors have recently hypothesized that unresolved or latent inflammation and sepsis may be an important factor that contributes to death following successful discharge from the ICU. AIM:T...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-10-17
更新日期:2010-09-27 00:00:00
abstract:BACKGROUND:Endotracheal extubation is the most crucial step during emergence from general anesthesia and is usually carried out when patients are awake with return of airway reflexes. Alternatively, extubations can also be accomplished while patients are deeply anesthetized, a technique known as "deep extubation", in o...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-01191-8
更新日期:2020-10-29 00:00:00
abstract:BACKGROUND:Acute kidney injury (AKI) is a common complication following non-cardiac surgery with adverse short- and long- term morbidity and mortality. Evidence shows that hypoalbuminemia is associated with increased AKI risk in patients with infectious diseases and cancer and following cardiac surgery and transplant s...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-019-0842-3
更新日期:2019-09-02 00:00:00
abstract:BACKGROUND:Gabapentin is an antiepileptic drug used in a variety of chronic pain conditions. Increasing numbers of randomized trials indicate that gabapentin is effective as a postoperative analgesic. This procedure-specific systematic review aims to analyse the 24-hour postoperative effect of gabapentin on acute pain ...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-7-6
更新日期:2007-07-07 00:00:00
abstract:BACKGROUND:As the field of interventional pulmonology (IP) expands, anesthesia services are increasingly being utilized when complex procedures of longer duration are performed on sicker patients with high risk co-morbidities and lung pathology. Yet, evidence on the optimal anesthetic management for these patients rema...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-019-0872-x
更新日期:2019-10-31 00:00:00
abstract:BACKGROUND:Although mortality after cardiac surgery has significantly decreased in the last decade, patients still experience clinically relevant postoperative complications. Among others, atrial fibrillation (AF) is a common consequence of cardiac surgery, which is associated with prolonged hospitalization and increas...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-017-0455-7
更新日期:2017-12-02 00:00:00
abstract:BACKGROUND:Tenascin-C is a pro-inflammatory glycoprotein with various biological functions. High expression of tenascin-C is found in inflammation, tissue remodeling, and autoimmune diseases. However, its expression and clinical significance in sepsis remain unclear. This study was designed to investigate the relations...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-018-0634-1
更新日期:2018-11-15 00:00:00
abstract:BACKGROUND:Aspiration-induced lung injury can decrease gas exchange and increase mortality. Acute lung injury following acid aspiration is characterized by elevated pulmonary blood flow (PBF) in damaged lung areas in the early inflammation stage. Knowledge of PBF patterns after acid aspiration is important for targetin...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-015-0013-0
更新日期:2015-03-18 00:00:00
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journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-01087-7
更新日期:2020-07-17 00:00:00
abstract:BACKGROUND:Knee arthroplasty leads to postoperative pain. This study compares analgesia and postoperative bleeding achieved by intrathecal morphine with a continuous femoral plus single-shot sciatic nerve block. METHODS:A randomized non-blinded clinical trial enrolled patients aged over 18 years old, ASA I to III who ...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-017-0355-x
更新日期:2017-05-12 00:00:00
abstract:BACKGROUND:Pulse pressure (PPV) and stroke volume (SVV) variations may not be reliable in the setting of pulmonary hypertension and/or right ventricular (RV) failure. We hypothesized that RV afterload increase attenuates SVV and PPV during hypovolemia in a rabbit model of pulmonary embolism (PE) secondary to RV dysfunc...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-017-0329-z
更新日期:2017-03-03 00:00:00
abstract:BACKGROUND:Laryngeal mask airway is a supraglottic airway device which has led to a fundamental change in the management of modern general anesthesia. In the present study; we evaluated the laryngeal mask airway insertion conditions and hemodynamic changes comparing ketamine-propofol mixture (ketofol) with propofol. Th...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-019-0711-0
更新日期:2019-03-20 00:00:00
abstract:BACKGROUND:During an emergency endotracheal intubation, rapid sequence induction intubation (RSII) with cricoid pressure (CP) is frequently implemented to prevent aspiration pneumonia. We evaluated the CVS in endotracheal intubation in RSII with CP, in comparison with a direct laryngoscope (DL). METHODS:One hundred fi...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-019-0703-0
更新日期:2019-03-04 00:00:00
abstract:BACKGROUND:Abnormal laryngeal structures are likely to be associated with a difficult laryngoscopy procedure. Currently, laryngeal structures can be measured by ultrasonography, however, little research has been performed on the potential role of ultrasound on the evaluation of a difficult laryngoscopy. The present stu...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-01053-3
更新日期:2020-06-02 00:00:00
abstract:BACKGROUND:Perioperative immune function plays an important role in the prognosis of patients. Several studies have indicated that low-dose opioid receptor blockers can improve immune function. METHODS:Sixty-nine patients undergoing video-assisted thoracoscopic resection of the lung cancer were randomly assigned to ei...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12871-019-0912-6
更新日期:2019-12-19 00:00:00
abstract:BACKGROUND:Desflurane during early reperfusion has been shown to postcondition human myocardium, in vitro. We investigated the role of adenosine and bradykinin receptors, and generation of radical oxygen species in desflurane-induced postconditioning in human myocardium. METHODS:We recorded isometric contraction of hu...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-10-12
更新日期:2010-07-29 00:00:00
abstract:BACKGROUND:We report a case of severe upper airway obstruction due to a retropharyngeal hematoma that presented nearly one day after a precipitating traumatic injury. Retropharyngeal hematomas are rare, but may cause life-threatening airway compromise. CASE PRESENTATION:A 50 year-old man developed severe dyspnea with ...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-7-2
更新日期:2007-03-12 00:00:00
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journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-01117-4
更新日期:2020-08-24 00:00:00
abstract:BACKGROUND:Sevoflurane is suitable for low-flow anesthesia (LFA). LFA needs a wash-in phase. The reported sevoflurane wash-in schemes lack simplicity, target coverage, and applicability. We proposed a one-step 1-1-8 wash-in scheme for sevoflurane LFA to be used with both N2O and Air. The objective of our study was to i...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-0940-2
更新日期:2020-01-24 00:00:00
abstract:BACKGROUND:Low-flow sevoflurane anesthesia has been shown to influence renal function in rats, but not in adult humans. Presently, no study has assessed the effects of sevoflurane on renal function in low birth weight infants. Our aim was to study the renal function in low birth weight infants undergoing surgery with l...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-15-6
更新日期:2015-01-21 00:00:00
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journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-14-52
更新日期:2014-07-11 00:00:00
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journal_title:BMC anesthesiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/1471-2253-14-102
更新日期:2014-11-15 00:00:00
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journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-016-0264-4
更新日期:2016-10-14 00:00:00
abstract:BACKGROUND:The effect of adding clonidine to local anesthetics for nerve or plexus blocks remains unclear. Most of the studies in adults have demonstrated the positive effects of clonidine on intra- and postoperative analgesia when used as an adjunctive agent or in some cases as a single to regional techniques. In the ...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-12-2
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Since blood pressure tends to be unstable during induction of anesthesia in patients undergoing cardiovascular surgery, an artery catheter is often inserted before induction to continuously monitor arterial pressure during induction of anesthesia. ClearSight System™ enables noninvasive continuous measurement...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-020-01091-x
更新日期:2020-07-20 00:00:00
abstract:BACKGROUND:Fentanyl and remifentanil are widely used opioids in surgery, but it has not been evaluated whether the choice of opioids during surgery affects the patients' postoperative quality of recovery. Accordingly, we aim to compare postoperative recovery of fentanyl-based anesthesia with remifentanil-based anesthes...
journal_title:BMC anesthesiology
pub_type: 杂志文章,随机对照试验
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更新日期:2018-07-11 00:00:00
abstract:BACKGROUND:The present anonymous multicenter online survey was conducted to evaluate the application of regional anaesthesia techniques as well as the used local anaesthetics and adjuncts at German and Austrian university hospitals. METHODS:39 university hospitals were requested to fill in an online questionnaire, to ...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-10-4
更新日期:2010-04-17 00:00:00
abstract::We have developed a two-step procedure for preparing the skin before peripheral venous catheter (PVC) insertions. This procedure involves two successive swabbings with wipes soaked in alcoholic antiseptic. We investigated whether this two-step procedure was as effective and safe as the standard four-step procedure--wa...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/1471-2253-7-1
更新日期:2007-01-31 00:00:00
abstract:BACKGROUND:This paper describes the design of a multifunction alerting display for intraoperative anesthetic care. The design was inspired by the multifunction primary flight display used in modern aviation. RESULTS:The display retrieves live data from multiple sources; the physiologic monitors, the anesthesia informa...
journal_title:BMC anesthesiology
pub_type: 杂志文章
doi:10.1186/s12871-018-0478-8
更新日期:2018-02-05 00:00:00