Clapping-surpressed focal spikes in EEG may be unique for the patients with rett syndrome : a case report.

abstract：BACKGROUND:Cerebrospinal fluid (CSF) biomarkers Aβ1-42, t-tau and p-tau have a characteristic pattern in Alzheimer's Disease (AD). Their roles in HIV-associated neurocognitive disorder (HAND) remains unclear. METHODS:Adults with chronic treated HIV disease were recruited (n = 43, aged 56.7 ± 7.9; 32% aged 60+; median ...

journal_title：BMC neurology

authors： Cysique LA,Hewitt T,Croitoru-Lamoury J,Taddei K,Martins RN,Chew CS,Davies NN,Price P,Brew BJ

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Non-ataxic symptoms of spinocerebellar ataxias (SCAs) vary widely and often overlap with various types of SCAs. Duration and severity of the disease and genetic background may play a role in such phenotypic diversity. We conducted the study in order to study clinical characteristics of common SCAs in Thailan...

journal_title：BMC neurology

authors： Boonkongchuen P,Pongpakdee S,Jindahra P,Papsing C,Peerapatmongkol P,Wetchaphanphesat S,Paiboonpol S,Dejthevaporn C,Tanprawate S,Nudsasarn A,Jariengprasert C,Muntham D,Ingsathit A,Pulkes T

更新日期：2014-04-05 00:00:00

abstract：BACKGROUND:Primary familial brain calcification is a rare autosomal dominant or recessive neurodegenerative disease, characterized by bilateral brain calcifications in different areas of the brain. It is a clinically heterogeneous disease and patients are reported to exhibit a wide spectrum of neurological and psychiat...

journal_title：BMC neurology

authors： Mathorne SW,Sørensen K,Fagerberg C,Bode M,Hertz JM

更新日期：2019-04-12 00:00:00

abstract：BACKGROUND:The mechanisms underlying the interictal habituation deficit of cortical visual evoked potentials (VEP) in migraine are not well understood. Abnormal long-term functional plasticity of the visual cortex may play a role and it can be assessed experimentally by light deprivation (LD). METHODS:We have compared...

journal_title：BMC neurology

authors： Coppola G,Crémers J,Gérard P,Pierelli F,Schoenen J

更新日期：2011-07-27 00:00:00

abstract：BACKGROUND:THK5351 and flortaucipir tau ligands have high affinity for paired helical filament tau, yet diverse off-target bindings have been reported. Recent data support the hypothesis that THK5351 binds to monoamine oxidase B (MAO-B) expressed from reactive astrocytes and that flortaucipir has an affinity toward MAO...

journal_title：BMC neurology

authors： Kim HJ,Cho H,Park S,Jang H,Ryu YH,Choi JY,Moon SH,Oh SJ,Oh M,Na DL,Lyoo CH,Kim EJ,Seeley WW,Kim JS,Choi KC,Seo SW

更新日期：2019-08-29 00:00:00

abstract：BACKGROUND:Hemifacial spasm (HFS) is a disabling neurological condition. Vascular tortuosity in HFS patients has not been quantified objectively and its relationship with hypertension and posterior fossa volume (PF) is unknown. In a case control magnetic resonance imaging and angiographic (MRI/A) study, we quantified a...

journal_title：BMC neurology

authors： Edmond EC,Sim SX,Li HH,Tan EK,Chan LL

更新日期：2016-07-29 00:00:00

abstract：BACKGROUND:This multicenter, double-blind, placebo-controlled study assessed the efficacy of rotigotine transdermal patch on apathy and motor symptoms in patients with Parkinson's disease (PD). METHODS:Patients with PD-associated apathy (Unified Parkinson's Disease Rating Scale [UPDRS] I item 4 [motivation] ≥2 and pat...

journal_title：BMC neurology

authors： Hauser RA,Slawek J,Barone P,Dohin E,Surmann E,Asgharnejad M,Bauer L

更新日期：2016-06-07 00:00:00

abstract：BACKGROUND:Glutamic acid decarboxylase (GAD) is the rate-limiting enzyme for producing γ-aminobutyric acid, and it has been suggested that antibodies against GAD play a role in neurological conditions and type 1 diabetes. However, it is not known whether dementia appears as the sole neurological manifestation associate...

journal_title：BMC neurology

authors： Takagi M,Yamasaki H,Endo K,Yamada T,Kaneko K,Oka Y,Mori E

更新日期：2011-12-21 00:00:00

abstract：BACKGROUND:The primary aim of this study is to demonstrate the feasibility of utilizing doxycycline to suppress matrix metalloproteinase-9 (MMP-9) in brain arteriovenous malformations (AVMs). METHODS:Ex-vivo treatment of AVM tissues: Intact AVM tissues were treated with doxycycline for 48 hours. Active and total MMP-9...

journal_title：BMC neurology

authors： Hashimoto T,Matsumoto MM,Li JF,Lawton MT,Young WL,University of California, San Francisco, BAVM Study Group.

更新日期：2005-01-24 00:00:00

abstract：BACKGROUND:To evaluate the relationship between the flow signal intensity of branch arteries distal to the stenosis on 3-dimensional (3D) time-of-flight (TOF) magnetic resonance angiography (MRA) and the risk of stroke recurrence in patients with severe middle cerebral artery (MCA) trunk stenosis. METHODS:We prospecti...

journal_title：BMC neurology

authors： Chen H,Li Z,Hong H,Xing S,Liu G,Zhang A,Tan S,Zhang J,Zeng J

更新日期：2015-09-16 00:00:00

abstract：BACKGROUND:It has been recently demonstrated that in Frontotemporal Lobar Degeneration (FTLD) memory deficits at presentation are commoner than previously thought. Apolipoprotein E (ApoE) genotype, the major genetic risk factor in sporadic late-onset Alzheimer Disease (AD), modulates cerebral perfusion in late middle-a...

journal_title：BMC neurology

authors： Borroni B,Perani D,Archetti S,Agosti C,Paghera B,Bellelli G,Di Luca M,Padovani A

更新日期：2006-08-24 00:00:00

abstract：BACKGROUND:Different apoptosis pathways activate caspase-3. In a study involving 27 patients with traumatic brain injury (TBI), higher caspase-3 levels were found in contusion brain tissue resected from non-survivors than from survivors. The objective of this study was to determine whether there is an association in TB...

journal_title：BMC neurology

authors： Lorente L,Martín MM,Argueso M,Ramos L,Solé-Violán J,Riaño-Ruiz M,Jiménez A,Borreguero-León JM

更新日期：2015-11-06 00:00:00

abstract：BACKGROUND:Economic costs related to treatment of multiple sclerosis (MS) must be justified by health state, quality of life (QOL) and social participation improvement. This study aims to describe correlations between social participation, economic costs, utility and MS-specific QOL in a sample of patients with MS (pwM...

journal_title：BMC neurology

authors： Kwiatkowski A,Marissal JP,Pouyfaucon M,Vermersch P,Hautecoeur P,Dervaux B

更新日期：2014-05-27 00:00:00

abstract：BACKGROUND:Silent brain infarcts are detected by neuroimaging in up to 20% of asymptomatic patients based on population studies. They are five times more frequent than stroke in general population, and increase significantly both with advancing age and hypertension. Moreover, they are independently associated with the ...

journal_title：BMC neurology

authors： Riba-Llena I,Jarca CI,Mundet X,Tovar JL,Orfila F,López-Rueda A,Nafría C,Fernández JL,Castañé X,Domingo M,Alvarez-Sabín J,Fernández-Cortiñas I,Maisterra O,Montaner J,Delgado P

更新日期：2013-10-02 00:00:00

abstract：BACKGROUND:Cubital tunnel syndrome is common nerve compression syndrome among peripheral nerve compression diseases. However, the syndrome caused by intraneural ganglion cysts has been rarely reported. Medical approaches, like ultrasound-guided aspiration and open surgical treatment remain to be discussed. CASE PRESEN...

journal_title：BMC neurology

authors： Li P,Lou D,Lu H

更新日期：2018-12-22 00:00:00

abstract：BACKGROUND:An Early Supported Discharge (ESD) and rehabilitation from a coordinated team in the home environment is recommended in several high-income countries for patients with mild to moderate symptoms after stroke. Returning home from the hospital takes place very early in Sweden today (12 days post stroke), thus t...

journal_title：BMC neurology

authors： Nordin Å,Sunnerhagen KS,Axelsson ÅB

更新日期：2015-11-16 00:00:00

abstract：BACKGROUND:Anti-epileptic drugs (AEDs) are frequently prescribed to persons with HIV/AIDS receiving combination antiretroviral therapy (cART) although the extent of AED use and their interactions with cART are uncertain. Herein, AED usage, associated toxicities and immune consequences were investigated. METHODS:HIV re...

journal_title：BMC neurology

authors： Lee K,Vivithanaporn P,Siemieniuk RA,Krentz HB,Maingat F,Gill MJ,Power C

更新日期：2010-06-17 00:00:00

abstract：:An international expert consensus committee recently recommended a brief battery of tests for cognitive evaluation in multiple sclerosis. The Brief International Cognitive Assessment for MS (BICAMS) battery includes tests of mental processing speed and memory. Recognizing that resources for validation will vary intern...

journal_title：BMC neurology

authors： Benedict RH,Amato MP,Boringa J,Brochet B,Foley F,Fredrikson S,Hamalainen P,Hartung H,Krupp L,Penner I,Reder AT,Langdon D

更新日期：2012-07-16 00:00:00

abstract：BACKGROUND:Sciatica is a condition that is characterised by radicular pain in the leg and primarily caused by a herniated lumbar intervertebral disk. In addition to leg pain, patients can experience back pain, leg numbness and leg weakness resulting in decreased productivity and social activity. The majority of sciatic...

journal_title：BMC neurology

authors： Verheijen E,Munts AG,van Haagen O,de Vries D,Dekkers O,van den Hout W,Vleggeert-Lankamp C

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Carotid rete mirabile (RM) is a meshwork of multiple, freely intercommunicating arterioles that reconstitute the absent or hypoplastic segments of the internal carotid artery (ICA). Carotid RM has been reported to be associated with cerebrovascular diseases. However, it is rarely associated with moyamoya-pat...

journal_title：BMC neurology

authors： Chen H,Hou K,Wang X,Xu K,Yu J

更新日期：2019-04-02 00:00:00

abstract：BACKGROUND:The production of inflammatory cytokines resulting from amyloid β (Aβ) is associated with the initiation of Alzheimer's disease (AD). Atorvastatin (ATV) has been reported to improve AD, however, it is unclear how the anti-inflammatory mechanism is linked with its protection against the impairment of spatial ...

journal_title：BMC neurology

authors： Zhao L,Chen T,Wang C,Li G,Zhi W,Yin J,Wan Q,Chen L

更新日期：2016-02-04 00:00:00

abstract：BACKGROUND:Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of unknown cause involving the brain and accompanied by prominent eosinophilia. Intracardiac thrombosis is a major cardiac complication of EGPA that may cause thromboembolism. CASE PRESENTATION:A 53-year-old man presenting wi...

journal_title：BMC neurology

authors： Hira K,Shimura H,Kamata R,Takanashi M,Hashizume A,Takahashi K,Sugiyama M,Izumi H,Hattori N,Urabe T

更新日期：2019-11-15 00:00:00

abstract：BACKGROUND:Recent studies suggest that epigenetic factors may play an important role in the pathogenesis of Parkinson's disease (PD). In our previous work, we sequenced the exomes of sixteen patients from eight Chinese PD families using whole exome sequencing technology, consequently three patients from different pedig...

journal_title：BMC neurology

authors： Liao XX,Zhan ZX,Luo YY,Li K,Wang JL,Guo JF,Yan XX,Xia K,Tang BS,Shen L

更新日期：2013-12-11 00:00:00

abstract：BACKGROUND:Due to lack of any curative therapy for ALS, symptomatic treatment and maintenance of quality of life (QoL) is very important. We aimed to characterize the affected domains of QoL in ALS patients and to identify factors which are associated with reduced QoL and increased depression. METHODS:159 ALS patients...

journal_title：BMC neurology

authors： Körner S,Kollewe K,Abdulla S,Zapf A,Dengler R,Petri S

更新日期：2015-05-16 00:00:00

abstract：BACKGROUND:Presently, for patients presenting with suspected Normal Pressure Hydrocephalus (NPH) who undergo temporary drainage of cerebrospinal fluid (CSF) there is no defined model to differentiate chance improvement form clinical significance change at the individual patient level. To address this lack of informatio...

journal_title：BMC neurology

authors： Davis A,Yasar S,Emerman I,Gulyani S,Khingelova K,Rao A,Manthripragada L,Luciano M,Moghekar A

更新日期：2020-04-16 00:00:00

abstract：BACKGROUND:Delayed post-hypoxic leukoencephalopathy (DPHL) is a demyelinating syndrome characterized by neurological relapse after an initial recovery from hypoxic brain injury. We describe a patient with impaired consciousness following DPHL, concurrent with injury of the ascending reticular activating system (ARAS) s...

journal_title：BMC neurology

authors： Jang SH,Kwon HG

更新日期：2017-07-19 00:00:00

abstract：BACKGROUND:Spastic paraplegia, optic atrophy and neuropathy (Spoan syndrome) is an autosomal recessive disease with approximately 70 cases recorded in Brazil and Egypt. METHODS:This is a prospective longitudinal study performed with 47 patients affected with Spoan syndrome of seven communities of Rio Grande do Norte (...

journal_title：BMC neurology

authors： Galvão CRC,Cavalcante PMA,Olinda R,Graciani Z,Zatz M,Kok F,Santos S,Lancman S

更新日期：2019-10-27 00:00:00

abstract：BACKGROUND:Women have been reported to show more frequent recanalization and better recovery after intravenous (IV) recombinant tissue plasminogen activator (rt-PA) treatment for acute stroke compared with men. To investigate this we studied a series of stroke patients receiving IV rt-PA and undergoing acute transcrani...

journal_title：BMC neurology

authors： Al-hussain F,Hussain MS,Molina C,Uchino K,Shuaib A,Demchuk AM,Alexandrov AV,Saqqur M,CLOTBUST Investigators.

更新日期：2014-03-26 00:00:00

abstract：BACKGROUND:Patients with ischemic cerebrovascular diseases are more likely to suffer from intracranial aneurysms, and their surgical treatment has a growing controversy in this condition. The current case series was aimed at exploring surgical treatment and perioperative management of intracranial aneurysms in Chinese ...

journal_title：BMC neurology

authors： Zheng Y,Wu C

更新日期：2018-09-14 00:00:00

abstract：BACKGROUND:Balanced Steady State Free Precession (b-SSFP) sequences and the newly developed Fast-Spin-Echo (FSE)-sequences enable an optimized visualization of neurovascular compression (NVC) in patients with trigeminal neuralgia (TN). Arterial conflicts are mostly associated with a favorable outcome of microvascular d...

journal_title：BMC neurology

authors： Müller S,Khadhraoui E,Khanafer A,Psychogios M,Rohde V,Tanrikulu L

更新日期：2020-07-14 00:00:00