High infiltration of mast cells positive to tryptase predicts worse outcome following resection of colorectal liver metastases.

abstract：BACKGROUND:Short telomeres have been associated with increased risk of many cancers, particularly cancers of the gastrointestinal tract including esophagus and stomach. However, the association between telomere length (TL) and colorectal cancer and its precursors, colorectal polyps, is not clear. METHODS:We investigat...

journal_title：BMC cancer

authors： Hardikar S,Burnett-Hartman AN,Phipps AI,Upton MP,Zhu LC,Newcomb PA

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Myxoid liposarcoma (MLS) has the tendency to metastasize extrapulmonary. Although prognostic factors at the initial diagnosis of MLS have been reported, those at diagnosis of metastasis remain unclear. The purpose of this study was to investigate the prognostic factors for disease-specific survival at the in...

journal_title：BMC cancer

authors： Shinoda Y,Kobayashi E,Kobayashi H,Mori T,Asano N,Nakayama R,Morioka H,Iwata S,Yonemoto T,Ishii T,Hiruma T,Kawai A,Kawano H

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:Kaiso has been identified as a new member of the POZ-zinc finger family of transcription factors that are implicated in development and cancer. Although controversy still exists, Kaiso is supposed to be involved in human cancer. However, there is limited information regarding the clinical significance of cyt...

journal_title：BMC cancer

authors： Dai SD,Wang Y,Miao Y,Zhao Y,Zhang Y,Jiang GY,Zhang PX,Yang ZQ,Wang EH

更新日期：2009-06-09 00:00:00

abstract：BACKGROUND:Vinflunine is recommended in the European guideline for the treatment of advanced or metastatic urothelial cell carcinoma (UCC) after failure of platinum-based therapy. METHODS:This prospective, non-interventional study investigated the safety and efficacy of vinflunine in platinum-pretreated UCC patients i...

journal_title：BMC cancer

authors： Retz M,de Geeter P,Goebell PJ,Matz U,de Schultz W,Hegele A

更新日期：2015-06-04 00:00:00

abstract：BACKGROUND:Diffusion weighted magnetic resonance imaging (DW-MRI) holds great potential for monitoring treatment response in cancer patients shortly after initiation of radiotherapy. It is hypothesized that a decrease in cellular density of irradiated cancerous tissue will lead to an increase in quantitative apparent d...

journal_title：BMC cancer

authors： Fliedner FP,Engel TB,El-Ali HH,Hansen AE,Kjaer A

更新日期：2020-02-19 00:00:00

abstract：BACKGROUND:Patients undergoing surgery for esophageal cancer have a high risk for postoperative deterioration of lung function and pulmonary complications. This is partly due to one-lung ventilation during thoracotomy. This often accounts for prolonged stay on intensive care units, delayed postoperative reconvalescence...

journal_title：BMC cancer

authors： Pfirrmann D,Tug S,Brosteanu O,Mehdorn M,Busse M,Grimminger PP,Lordick F,Glatz T,Hoeppner J,Lang H,Simon P,Gockel I

更新日期：2017-06-14 00:00:00

abstract：BACKGROUND:No scientific consensus has been reached on whether active tobacco smoking causes breast cancer. We examine the association between active smoking and breast cancer risk in Denmark, which has some of the highest smoking and breast cancer rates in women worldwide. METHODS:We used the data from a nationwide D...

journal_title：BMC cancer

authors： Andersen ZJ,Jørgensen JT,Grøn R,Brauner EV,Lynge E

更新日期：2017-08-22 00:00:00

abstract：BACKGROUND:Aboriginal status has been unreliably and incompletely recorded in health and vital registration data collections for the most populous areas of Australia, including NSW where 29% of Australian Aboriginal people reside. This paper reports an assessment of Aboriginal status recording in NSW cancer registratio...

journal_title：BMC cancer

authors： Morrell S,You H,Baker D

更新日期：2012-05-06 00:00:00

abstract：BACKGROUND:Excision repair cross-complementing group 2 (ERCC2) plays important roles in the repair of DNA damage and adducts. Single nucleotide polymorphisms (SNPs) of ERCC2 gene are suspected to influence the risks of oral cancer. We performed a meta-analysis to systematically summarize the possible association of ERC...

journal_title：BMC cancer

authors： Zhang E,Cui Z,Xu Z,Duan W,Huang S,Tan X,Yin Z,Sun C,Lu L

更新日期：2013-12-12 00:00:00

abstract：BACKGROUND:Plenty of studies have demonstrated the prognostic value of various inflammation-based indexes in cancer. This study was designed to investigate the prognostic value of the C-reactive protein/albumin (CRP/Alb) ratio in esophageal squamous cell carcinoma. METHODS:A retrospective study of 423 cases with newly...

journal_title：BMC cancer

authors： Wei XL,Wang FH,Zhang DS,Qiu MZ,Ren C,Jin Y,Zhou YX,Wang DS,He MM,Bai L,Wang F,Luo HY,Li YH,Xu RH

更新日期：2015-05-02 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the incidence and prognostic value of disseminated tumor cells in bone marrow of breast carcinoma patients with early disease, and to analyze this finding in relation to lymph node involvement, determined by sentinel lymph node (SLN) biopsy analysis, and to prognostic...

journal_title：BMC cancer

authors： Solá M,Margelí M,Castellá E,Julian JF,Rull M,Gubern JM,Mariscal A,Barnadas A,Fraile M

更新日期：2011-06-16 00:00:00

abstract：BACKGROUND:New therapeutic principles in clinical oncology require the adjustment of response criteria to govern therapy decisions. For advanced hepatocellular carcinoma (HCC) a new era has recently begun by the approval of the multikinase inhibitor sorafenib. As a unique feature, HCC usually develops in a diseased liv...

journal_title：BMC cancer

authors： Horger M,Lauer UM,Schraml C,Berg CP,Koppenhöfer U,Claussen CD,Gregor M,Bitzer M

更新日期：2009-06-28 00:00:00

abstract：BACKGROUND:Expression of Nodal, a member of the TGF-β superfamily, is commonly absent in differentiated tissues, while its re-expression occurs in a variety of human malignancy. However, little is known about its involvement in ovarian tumorigenesis. Herein, we focused on the functional roles of Nodal in ovarian endome...

journal_title：BMC cancer

authors： Miura R,Yokoi A,Matsumoto T,Oguri Y,Hashimura M,Tochimoto M,Kajita S,Saegusa M

更新日期：2019-04-03 00:00:00

abstract：BACKGROUND:Some historic breakthroughs have been made in immunotherapy of advanced cancer. However, there is still little research on immunotherapy in prostate cancer. We explored the relationship between immune cell infiltration and prostate cancer recurrence and tried to provide new ideas for the treatment of prostat...

journal_title：BMC cancer

authors： Rui X,Shao S,Wang L,Leng J

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:The purpose of this review is to update previously published reviews on exercise programming in exercise trials in prostate cancer survivors. We evaluated: 1) the application of the principles of exercise training in prescribed programs; 2) the reporting of the components of the exercise prescription; and 3)...

journal_title：BMC cancer

authors： Neil-Sztramko SE,Medysky ME,Campbell KL,Bland KA,Winters-Stone KM

更新日期：2019-04-05 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is a frequent type of primary liver cancer, and its prevalence is increasing worldwide. Indeed, the underlying molecular mechanism is not well understood. Previous studies have shown evidence that tight junction (TJ) components were correlated with carcinogenesis and tumor deve...

journal_title：BMC cancer

authors： Ram AK,Pottakat B,Vairappan B

更新日期：2018-05-18 00:00:00

abstract：BACKGROUND:Cell migration and invasion are essential processes for metastatic dissemination of cancer cells. Significant progress has been made in developing new therapies against oncogenic signaling to eliminate cancer cells and shrink tumors. However, inherent heterogeneity and treatment-induced adaptation to drugs c...

journal_title：BMC cancer

authors： Shahi Thakuri P,Gupta M,Singh S,Joshi R,Glasgow E,Lekan A,Agarwal S,Luker GD,Tavana H

更新日期：2020-01-02 00:00:00

abstract：BACKGROUND:Tobacco smoke exposure may be associated with increased breast cancer risk, although the evidence supporting the association is inconclusive. We conducted a case-control study in Delaware, incorporating detailed exposure assessment for active and secondhand smoke at home and in the workplace. METHODS:Primar...

journal_title：BMC cancer

authors： Rollison DE,Brownson RC,Hathcock HL,Newschaffer CJ

更新日期：2008-06-02 00:00:00

abstract：BACKGROUND:We sought to determine the comparative diagnostic performance of standard b-value (800-1000 s/mm2) versus low b-value (400-500 s/mm2) diffusion-weighted magnetic resonance imaging (DW-MRI) in the detection of renal cell carcinoma (RCC). METHOD:After a systematic review of the available literature, studies w...

journal_title：BMC cancer

authors： Tang Y,Zhou Y,Du W,Liu N,Zhang C,Ouyang T,Hu J

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:Lymphovascular invasion (LVI) is a vital risk factor for prognosis across cancers. We aimed to develop a scoring system for stratifying LVI risk in patients with breast cancer. METHODS:A total of 301 consecutive patients (mean age, 49.8 ± 11.0 years; range, 29-86 years) with breast cancer confirmed by patho...

journal_title：BMC cancer

authors： Ni-Jia-Ti MY,Ai-Hai-Ti DL,Huo-Jia AS,Wu-Mai-Er PL,A-Bu-Li-Zi AB,Shi Y,Rou-Zi NE,Su WJ,Dai GZ,Da-Mo-la MH

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:Ovarian cancer is the leading cause of death among gynecologic diseases in Western countries. We have previously identified a miR-200-E-cadherin axis that plays an important role in ovarian inclusion cyst formation and tumor invasion. The purpose of this study was to determine if the miR-200 pathway is invol...

journal_title：BMC cancer

authors： Yang J,Zhou Y,Ng SK,Huang KC,Ni X,Choi PW,Hasselblatt K,Muto MG,Welch WR,Berkowitz RS,Ng SW

更新日期：2017-06-17 00:00:00

abstract：BACKGROUND:Cancer services are inaccessible in many low-income countries, and few published examples describe oncology programs within the public sector. In 2011, the Rwanda Ministry of Health (RMOH) established Butaro Cancer Center of Excellence (BCCOE) to expand cancer services nationally. In hopes of informing cance...

journal_title：BMC cancer

authors： Tapela NM,Mpunga T,Hedt-Gauthier B,Moore M,Mpanumusingo E,Xu MJ,Nzayisenga I,Hategekimana V,Umuhizi DG,Pace LE,Bigirimana JB,Wang J,Driscoll C,Uwizeye FR,Drobac PC,Ngoga G,Shyirambere C,Muhayimana C,Lehmann L,Shulma

更新日期：2016-03-18 00:00:00

abstract：BACKGROUND:Loss of DNA mismatch repair (MMR) in humans, mainly due to mutations in the hMLH1 gene, is linked to hereditary nonpolyposis colorectal cancer (HNPCC). Because not all MLH1 alterations result in loss of MMR function, accurate characterization of variants and their classification in terms of their effect on M...

journal_title：BMC cancer

authors： Vogelsang M,Comino A,Zupanec N,Hudler P,Komel R

更新日期：2009-10-28 00:00:00

abstract：BACKGROUND:Two functional single nucleotide polymorphisms (SNPs) in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene, C677T and A1298C, lead to decreased enzyme activity and affect chemosensitivity of tumor cells. We investigated whether these MTHFR SNPs were associated with breast cancer survival in African-A...

journal_title：BMC cancer

authors： Martin DN,Boersma BJ,Howe TM,Goodman JE,Mechanic LE,Chanock SJ,Ambs S

更新日期：2006-10-27 00:00:00

abstract：BACKGROUND:To compare the value of two dynamic contrast-enhanced Magnetic Resonance Images (DCE-MRI) reconstruction approaches, namely golden-angle radial sparse parallel (GRASP) and view-sharing with golden-angle radial profile (VS-GR) reconstruction, and evaluate their values in assessing response to neoadjuvant chem...

journal_title：BMC cancer

authors： Lu Y,Ma L,Qin J,Wang Z,Guo J,Zhao Y,Zhang H,Yan X,Liu H,Li H,Kamel IR,Qu J

更新日期：2019-10-24 00:00:00

abstract：BACKGROUND:As inadequate pain communication contributes to difficulties in optimizing outcomes of outpatients, we investigated the effect of reinforced education using WeChat App to the opioid titration treatment of cancer-related pain in the outpatient setting. METHODS:We conducted a prospective study to compare rein...

journal_title：BMC cancer

authors： Peng Z,Li L,Chen Y,Feng Z,Fang X

更新日期：2020-09-04 00:00:00

abstract：BACKGROUND:Cholangiocarcinoma (CC) is a primary liver cancer with increasing incidence worldwide. Despite all efforts made in past years, prognosis remains to be poor. At least in part, this might be explained by a pronounced resistance of CC cells to undergo apoptosis. Thus, new therapeutic strategies are imperatively...

journal_title：BMC cancer

authors： Lieke T,Ramackers W,Bergmann S,Klempnauer J,Winkler M,Klose J

更新日期：2012-10-11 00:00:00

abstract：:Chimeric antigen receptor T (CAR-T) cells are a promising new treatment for patients with relapsed or refractory hematologic malignancies, including lymphoma. Given the success of CAR-T cells directed against CD19, new targets are being developed and tested, since not all lymphomas express CD19. CD30 is promising targ...

journal_title：BMC cancer

authors： Grover NS,Savoldo B

更新日期：2019-03-06 00:00:00

abstract：BACKGROUND:RASSF1A gene silencing by DNA methylation has been suggested as a major event in pancreatic endocrine tumor (PET) but RASSF1A expression has never been studied. The RASSF1 locus contains two CpG islands (A and C) and generates seven transcripts (RASSF1A-RASSF1G) by differential promoter usage and alternative...

journal_title：BMC cancer

authors： Malpeli G,Amato E,Dandrea M,Fumagalli C,Debattisti V,Boninsegna L,Pelosi G,Falconi M,Scarpa A

更新日期：2011-08-12 00:00:00

abstract：BACKGROUND:Lung cancer is the most common cause of cancer related death worldwide. The majority of cases are detected at a late stage when prognosis is poor. The EarlyCDT®-Lung Test detects autoantibodies to abnormal cell surface proteins in the earliest stages of the disease which may allow tumour detection at an earl...

journal_title：BMC cancer

authors： Sullivan FM,Farmer E,Mair FS,Treweek S,Kendrick D,Jackson C,Robertson C,Briggs A,McCowan C,Bedford L,Young B,Vedhara K,Gallant S,Littleford R,Robertson J,Sewell H,Dorward A,Sarvesvaran J,Schembri S

更新日期：2017-03-11 00:00:00