Abstract：
BACKGROUND:Cryptosporidiosis is a gastrointestinal disease affecting many people worldwide. Disease incidence is often unknown and surveillance of human cryptosporidiosis is installed in only a handful of developed countries. A genetic marker that mirrors disease incidence is potentially a powerful tool for monitoring the two primary human infected species of Cryptosporidium. METHODS:We used the molecular epidemiological database with Cryptosporidium isolates from ZoopNet, which currently contains more than 1400 records with their sampling nations, and the names of the host species from which the isolates were obtained. Based on 296 C. hominis and 195 C. parvum GP60 sequences from human origin, the genetic diversities of Cryptosporidium was estimated for several nations. Notified cases of human cryptosporidiosis were collected from statistics databases for only four nations. RESULTS:Genetic diversities of C. hominis were estimated in 10 nations in 5 continents, and that of C. parvum of human origin were estimated in 15 nations. Correlation with reported incidence of human cryptosporidiosis in four nations (the Netherlands, United States, United Kingdom and Australia) was positive and significant. A linear model for testing the relationship between the genetic diversity and incidence produced a significantly positive estimate for the slope (P-value < 0.05). CONCLUSIONS:The hypothesis that genetic diversity at GP60 locus mirrors notification rates of human cryptosporidiosis was not rejected based on the data presented. Genetic diversity of C. hominis and C. parvum may therefore be an independent and complementary measure for quantifying disease incidence, for which only a moderate number of stool samples from each nation are sufficient data input.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Takumi K,Cacciò SM,van der Giessen J,Xiao L,Sprong Hdoi
10.1186/s13071-015-0921-3subject
Has Abstractpub_date
2015-06-06 00:00:00pages
308issn
1756-3305pii
10.1186/s13071-015-0921-3journal_volume
8pub_type
杂志文章abstract：BACKGROUND:In Egypt, liver flukes, Fasciola spp. (Digenea: Fasciolidae), have a serious impact on the farming industry and public health. Both Fasciola hepatica and Fasciola gigantica are known to occur in cattle, providing the opportunity for genetic recombination. Little is known on the identity and genetic variabili...
journal_title：Parasites & vectors
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journal_title：Parasites & vectors
pub_type： 杂志文章,评审
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journal_title：Parasites & vectors
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journal_title：Parasites & vectors
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journal_title：Parasites & vectors
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journal_title：Parasites & vectors
pub_type： 杂志文章
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journal_title：Parasites & vectors
pub_type： 杂志文章
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journal_title：Parasites & vectors
pub_type： 杂志文章
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journal_title：Parasites & vectors
pub_type： 杂志文章
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journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-151
更新日期：2014-04-01 00:00:00
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journal_title：Parasites & vectors
pub_type： 杂志文章
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journal_title：Parasites & vectors
pub_type： 杂志文章
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journal_title：Parasites & vectors
pub_type： 杂志文章
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journal_title：Parasites & vectors
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pub_type： 杂志文章
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更新日期：2018-05-24 00:00:00
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journal_title：Parasites & vectors
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journal_title：Parasites & vectors
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更新日期：2012-03-27 00:00:00
abstract：:Control and eventual elimination of human parasitic diseases in the People's Republic of China (P.R. China) requires novel approaches, particularly in the areas of diagnostics, mathematical modelling, monitoring, evaluation, surveillance and public health response. A comprehensive effort, involving the collaboration o...
journal_title：Parasites & vectors
pub_type： 杂志文章,评审
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更新日期：2012-10-04 00:00:00
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journal_title：Parasites & vectors
pub_type： 杂志文章
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更新日期：2015-09-04 00:00:00
abstract：BACKGROUND:Chhattisgarh state in central India is highly endemic for malaria and contributes about 13% of annually reported malaria cases in the country with predominance of P. falciparum. Entomological investigations were carried out in a tribal forested area of district Bastar located in the southern part of Chhattis...
journal_title：Parasites & vectors
pub_type： 杂志文章
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更新日期：2012-09-28 00:00:00
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journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1528-z
更新日期：2016-04-30 00:00:00
abstract：BACKGROUND:The efficacy of fluralaner for the treatment of Otodectes cynotis infestations in dogs and cats was evaluated after oral (dogs) or topical administration (dogs and cats). Twenty-four dogs and sixteen cats were experimentally infested with O. cynotis and randomly allocated to equal sized groups (n = 8/group)....
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1954-y
更新日期：2017-01-16 00:00:00
abstract：BACKGROUND:Zoonotic Cutaneous Leishmaniasis (ZCL) due to Leishmania major (L. major) is still a serious public health problem in Tunisia. This study aimed to compare the prevalence and risk factors associated with L. major infection in old and new foci using leishmanin skin test (LST) in central Tunisia. METHODS:A cro...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-386
更新日期：2014-08-20 00:00:00
