Abstract：
BACKGROUND:Zoonotic Cutaneous Leishmaniasis (ZCL) due to Leishmania major (L. major) is still a serious public health problem in Tunisia. This study aimed to compare the prevalence and risk factors associated with L. major infection in old and new foci using leishmanin skin test (LST) in central Tunisia. METHODS:A cross sectional household survey was carried out between January and May 2009 on a sample of 2686 healthy individuals aged between 5 and 65 years. We determined the prevalence of L. major infection using the LST. Risk factors of LST positivity were assessed using a logistic regression model. RESULTS:The overall prevalence of LST positivity was 57% (95% CI: 53-59). The prevalence of L. major infection was significantly higher in the old focus (99%; 95% CI: 98-100) than in the emerging foci (43%; 95% CI: 39-46) (p = <0.001). Multivariate analysis of LST positivity risk factors showed that age, the nature of the foci (old/emerging), personal and family history of ZCL are determinants of positive LST results. CONCLUSION:The results updated the current epidemiologic profile of ZLC in central Tunisia. Past history of transmission in a population should be considered as a potential confounder in future clinical trials for drugs and vaccines against L. major cutaneous leishmaniasis.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Bettaieb J,Toumi A,Chlif S,Chelghaf B,Boukthir A,Gharbi A,Ben Salah Adoi
10.1186/1756-3305-7-386subject
Has Abstractpub_date
2014-08-20 00:00:00pages
386issn
1756-3305pii
1756-3305-7-386journal_volume
7pub_type
杂志文章abstract：BACKGROUND:In Europe, hard ticks of the subgenus Pholeoixodes (Ixodidae: Ixodes) are usually associated with burrow-dwelling mammals and terrestrial birds. Reports of Pholeoixodes spp. from carnivores are frequently contradictory, and their identification is not based on key diagnostic characters. Therefore, the aims o...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2424-x
更新日期：2017-11-03 00:00:00
abstract：BACKGROUND:Many cases of cutaneous leishmaniasis (CL) have been recorded in the Jenin District based on their clinical appearance. Here, their parasites have been characterized in depth. METHODS:Leishmanial parasites isolated from 12 human cases of CL from the Jenin District were cultured as promastigotes, whose DNA w...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-121
更新日期：2012-06-18 00:00:00
abstract：BACKGROUND:The Lowland tapir (Tapirus terrestris) is the largest Brazilian mammal and despite being distributed in various Brazilian biomes, it is seriously endangered in the Atlantic Rainforest. These hosts were never evaluated for the presence of Trypanosoma parasites. METHODS:The Lowland tapirs were captured in the...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-6-349
更新日期：2013-12-11 00:00:00
abstract：BACKGROUND:Neorickettsia are a group of intracellular α proteobacteria transmitted by digeneans (Platyhelminthes, Trematoda). These endobacteria can also infect vertebrate hosts of the helminths and cause serious diseases in animals and humans. Neorickettsia have been isolated from infected animals and maintained in ce...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2123-7
更新日期：2017-04-13 00:00:00
abstract：BACKGROUND:Plasmodium vivax uses multiple ligand-receptor interactions for preferential invasion of human reticulocytes. Several of these ligands have been identified by in silico approaches based on the role displayed by their orthologs in other Plasmodium species during initial adhesion or invasion. However, the cell...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2185-6
更新日期：2017-05-18 00:00:00
abstract：BACKGROUND:Schistosomiasis studies in western Kenya have mainly focused on the intestinal form, with evidence of urinary schistosomiasis remaining anecdotal. Detailed disease mapping has been carried out predominantly along the shores of Lake Victoria, but there is a paucity of information on intestinal and urinary sch...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-125
更新日期：2014-03-25 00:00:00
abstract：BACKGROUND:Co-infections of multiple parasite species in hosts may lead to interspecific associations and subsequently shape the structure of a parasite community. However, few studies have focused on these associations in highly abundant parasite species or, in particular, investigated how the associations develop wit...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-4-85
更新日期：2011-05-20 00:00:00
abstract：BACKGROUND:The pork tapeworm, Taenia solium, is a serious public health problem in rural low-resource areas of Latin America, Africa and Asia, where the associated conditions of nuerocysticercosis (NCC) and porcine cysticercosis cause substantial health and economic harms. An accurate and validated transmission model f...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04226-8
更新日期：2020-07-24 00:00:00
abstract：BACKGROUND:Strongyloides stercoralis can undergo an alternative autoinfective life cycle in the host, which, in some individuals can lead to a lethal infection. However, due to a number of factors, such as, the majority of those infected are from low-income backgrounds and the limitation in experimental models for stud...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-014-0579-2
更新日期：2014-12-12 00:00:00
abstract：BACKGROUND:Parasitic infections may cause significant effects on behavior, learning, and memory of the host. In the brain of mice heavily infected with Angiostrongylus cantonensis, severe damage has been observed in the hippocampus. This component has been considered to have associations with spatial learning and memor...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04230-y
更新日期：2020-08-10 00:00:00
abstract：BACKGROUND:Ixodes ricinus is the most common tick species in Europe and the main vector for Borrelia burgdorferi (sensu lato) and tick-borne encephalitis virus (TBEV). It is involved also in the transmission of Borrelia miyamotoi, a relapsing fever spirochete that causes health disorders in humans. Little is known rega...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-3969-7
更新日期：2020-02-27 00:00:00
abstract：BACKGROUND:Swim bladder inflammation (SBI) is an important disease of common carp fingerlings in Central Europe. In the 1980s, its etiology was ascribed to multicellular proliferative stages of the myxozoan parasite Sphaerospora dykovae (formerly S. renicola). S. dykovae was reported to proliferate in the blood and in ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-398
更新日期：2014-08-28 00:00:00
abstract：: The brown dog tick (Rhipicephalus sanguineus) is the most widespread tick in the world and a well-recognized vector of many pathogens affecting dogs and occasionally humans. This tick can be found on dogs living in both urban and rural areas, being highly adapted to live within human dwellings and being active throug...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-3-26
更新日期：2010-04-08 00:00:00
abstract：BACKGROUND:Spatial modelling studies of schistosomiasis (SCH) are now commonplace. Covariate values are commonly extracted at survey locations, where infection does not always take place, resulting in an unknown positional exposure mismatch. The present research aims to: (i) describe the nature of the positional exposu...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3039-6
更新日期：2018-08-13 00:00:00
abstract：BACKGROUND:In 2011, we reported occurrence of natural human infections with Brugia pahangi, a filarial worm of dogs and cats, in a surburb of Kuala Lumpur, the capital city of Malaysia. Our preliminary entomological survey at that time suggested the mosquito species Armigeres subalbatus as the vector of the zoonotic in...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-6-219
更新日期：2013-07-30 00:00:00
abstract：BACKGROUND:Taenia solium is an important zoonotic parasite that infects humans as definitive host (taeniasis) and pigs as intermediate host (cysticercosis). Serological diagnosis of porcine cysticercosis is limited to antigen detection using ELISA, which is known to cross-react with other Taenia species, and antibody d...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3279-5
更新日期：2019-01-24 00:00:00
abstract：BACKGROUND:Schistosoma japonicum is one of the major causative agents of schistosomiasis. The pairing of males and females leads to female sexual maturation and maintains this mature state. However, the mechanisms by which pairing facilitates sexual maturation are yet to be investigated. METHODS:Parasites isolated fro...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-177
更新日期：2014-04-10 00:00:00
abstract：BACKGROUND:The water buffalo (Bubalus bubalis) is well adapted in some regions of the Amazon. Of all Brazilian states, Pará contains the largest number of this species, with 510,000 animals, approximately 38% of the Brazilian buffaloes. Despite the socioeconomic importance of bubaline farming in the northern region, li...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-2917-2
更新日期：2018-06-04 00:00:00
abstract：BACKGROUND:Fleas are obligate blood-feeding ectoparasites and vectors of several bacterial zoonotic pathogens as well as trypanosomes that parasitize rodents and other small mammals. During investigations of tick- and rodent-borne diseases in Mali, West Africa, we included fleas and rodent-borne trypanosomes, both of w...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1818-5
更新日期：2016-10-11 00:00:00
abstract：BACKGROUND:Pyrethroid resistance in African vector mosquitoes is a threat to malaria control. Resistant mosquitoes can survive insecticide doses that would normally be lethal. We studied effects of such doses on Plasmodium falciparum development inside kdr-resistant Anopheles gambiae s.s. in Uganda. METHODS:We collect...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1384-x
更新日期：2016-02-24 00:00:00
abstract：:Acaricidal (tick) and insecticidal (flea) efficacy of systemically and cutaneously distributed ectoparasiticide products for dogs are compared based on permethrin and fluralaner as representative molecules. Results of efficacy studies against fleas and ticks are reviewed that show generally good to excellent results. ...
journal_title：Parasites & vectors
pub_type： 杂志文章,评审
doi：10.1186/s13071-016-1719-7
更新日期：2016-08-08 00:00:00
abstract：BACKGROUND:Angiostrongylus cantonensis has been the only parasite among Angiostrongylidae to cause human central nervous system infection characterized by eosinophilic meningitis or meningoencephalitis. The mechanism of the extensive neurological impairments of hosts caused by A. cantonensis larvae remains unclear. The...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2565-y
更新日期：2017-12-19 00:00:00
abstract：:Here we describe a case of paediatric visceral leishmaniasis recorded in an infant initially suspected for acute lymphoblastic leukaemia due to the clinical and haematological presentation. Eventually the patient was found positive for Leishmania infantum infection and successfully treated. This case emphasises how pi...
journal_title：Parasites & vectors
pub_type： 信件
doi：10.1186/1756-3305-6-123
更新日期：2013-04-29 00:00:00
abstract：BACKGROUND:Filariasis and leishmaniasis are two neglected tropical diseases in Mali. Due to distribution and associated clinical features, both diseases are of concern to public health. The goal of this study was to determine the prevalence of co-infection with filarial (Wuchereria bancrofti and Mansonella perstans) an...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2531-8
更新日期：2018-01-08 00:00:00
abstract：BACKGROUND:Toxoplasma gondii is an intracellular protozoan parasite that infects a wide variety of warm-blooded hosts, including humans. Limited information about T. gondii infection in bats is available in China. The objective of the present study was to determine prevalence and genetic characterization of T. gondii i...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-014-0558-7
更新日期：2014-12-03 00:00:00
abstract：BACKGROUND:In the Eastern and Upper Midwestern regions of North America, Ixodes scapularis (L.) is the most abundant tick species encountered by humans and the primary vector of B. burgdorferi, whereas in the southeastern region Amblyomma americanum (Say) is the most abundant tick species encountered by humans but cann...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-139
更新日期：2012-07-10 00:00:00
abstract：BACKGROUND:Rhipicephalus microplus is a hard tick that has a major impact on cattle health in tropical and subtropical regions because it feeds on cattle and is implicated in the transmission of pathogens that cause diseases such as bovine anaplasmosis and babesiosis. Presently, acaricides are used to control tick infe...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2081-0
更新日期：2017-03-23 00:00:00
abstract：BACKGROUND:Hard ticks are hematophagous ectoparasites characterized by their long-term feeding. The saliva that they secrete during their blood meal is their crucial weapon against host-defense systems including hemostasis, inflammation and immunity. The anti-hemostatic, anti-inflammatory and immune-modulatory activiti...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-2874-9
更新日期：2018-05-24 00:00:00
abstract：BACKGROUND:The white-naped squirrel, Simosciurus nebouxii (previously known as Sciurus stramineus), has recently been identified as an important natural host for Trypanosoma cruzi in Ecuador. The nests of this species have been reported as having high infestation rates with the triatomine vector Rhodnius ecuadoriensis....
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3138-4
更新日期：2018-10-29 00:00:00
abstract：BACKGROUND:Fluralaner is a novel isoxazoline eliciting both acaricidal and insecticidal activity through potent blockage of GABA- and glutamate-gated chloride channels. The aim of the study was to investigate the susceptibility of juvenile stages of common tick species exposed to fluralaner through either contact (Rhip...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0704-x
更新日期：2015-02-08 00:00:00
