Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts.

abstract：OBJECTIVE:To investigate pharmaceutical or medical device industry funding of patient groups. DESIGN:Systematic review with meta-analysis. DATA SOURCES:Ovid Medline, Embase, Web of Science, Scopus, and Google Scholar from inception to January 2018; reference lists of eligible studies and experts in the field. ELIGIB...

journal_title：BMJ (Clinical research ed.)

authors： Fabbri A,Parker L,Colombo C,Mosconi P,Barbara G,Frattaruolo MP,Lau E,Kroeger CM,Lunny C,Salzwedel DM,Mintzes B

更新日期：2020-01-22 00:00:00

abstract：OBJECTIVE:To evaluate the effects on suicidal behaviour of legislation limiting the size of packs of paracetamol and salicylates sold over the counter. DESIGN:Before and after study. SETTING:UK population, with detailed monitoring of data from five liver units and seven general hospitals, between September 1996 and S...

journal_title：BMJ (Clinical research ed.)

authors： Hawton K,Townsend E,Deeks J,Appleby L,Gunnell D,Bennewith O,Cooper J

更新日期：2001-05-19 00:00:00

abstract：OBJECTIVE:To examine whether the decline in child injury death rates between 1981 and 1991 varied by social class. DESIGN:Comparison of class specific child injury death rates for 1979, 1980, 1982, and 1983, with those for the four years 1989-92. SETTING:England and Wales. SUBJECTS:Children aged 0-15 years. MAIN OU...

journal_title：BMJ (Clinical research ed.)

authors： Roberts I,Power C

更新日期：1996-09-28 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of early treatment for amblyopia in children. DESIGN:Follow up of outcomes of treatment for amblyopia in a randomised controlled trial comparing intensive orthoptic screening at 8, 12, 18, 25, 31, and 37 months (intensive group) with orthoptic screening at 37 months only (control ...

journal_title：BMJ (Clinical research ed.)

authors： Williams C,Northstone K,Harrad RA,Sparrow JM,Harvey I,ALSPAC Study Team.

更新日期：2002-06-29 00:00:00

abstract：OBJECTIVES:To relate cancer since entry into the Framingham Heart Study with the risk of incident Alzheimer's disease and to estimate the risk of incident cancer among participants with and without Alzheimer's disease. DESIGN:Community based prospective cohort study; nested age and sex matched case-control study. SET...

journal_title：BMJ (Clinical research ed.)

authors： Driver JA,Beiser A,Au R,Kreger BE,Splansky GL,Kurth T,Kiel DP,Lu KP,Seshadri S,Wolf PA

更新日期：2012-03-12 00:00:00

abstract：OBJECTIVE:To study the role of respiratory viruses in exacerbations of asthma in adults. DESIGN:Longitudinal study of 138 adults with asthma. SETTING:Leicestershire Health Authority. SUBJECTS:48 men and 90 women 19-46 years of age with a mean duration of wheeze of 19.6 years. 75% received regular treatment with bron...

journal_title：BMJ (Clinical research ed.)

authors： Nicholson KG,Kent J,Ireland DC

更新日期：1993-10-16 00:00:00

abstract：OBJECTIVES:To assess the long term clinical and cost effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) intervention compared with usual care in people with newly diagnosed type 2 diabetes. DESIGN:We undertook a cost-utility analysis that used data from a 12 month, mu...

journal_title：BMJ (Clinical research ed.)

authors： Gillett M,Dallosso HM,Dixon S,Brennan A,Carey ME,Campbell MJ,Heller S,Khunti K,Skinner TC,Davies MJ

更新日期：2010-08-20 00:00:00

abstract：OBJECTIVES:To investigate the consequences of longstanding obesity on left ventricular mass and structure and to examine the effects of weight loss on these variables. DESIGN:Cross sectional survey and controlled intervention study. SETTING:City of Gothenburg and surrounding areas. Sweden. SUBJECTS:41 obese patients...

journal_title：BMJ (Clinical research ed.)

authors： Karason K,Wallentin I,Larsson B,Sjöström L

更新日期：1997-10-11 00:00:00

abstract：OBJECTIVE:To examine how much oncologists tell patients about the survival benefit of palliative chemotherapy during consultations at which decisions about treatment are made. DESIGN:Qualitative study in which consultations were observed and digitally recorded. SETTING:Teaching hospital and district general hospital ...

journal_title：BMJ (Clinical research ed.)

authors： Audrey S,Abel J,Blazeby JM,Falk S,Campbell R

更新日期：2008-07-31 00:00:00

abstract：OBJECTIVES:To identify risk factors predisposing to the development of flucloxacillin associated jaundice. DESIGN:Case-control study. Medical records of cases and controls were reviewed and information recorded on standard data collection forms. SETTING:Alfred Hospital recruiting subjects from Melbourne, Sydney, and ...

journal_title：BMJ (Clinical research ed.)

authors： Fairley CK,McNeil JJ,Desmond P,Smallwood R,Young H,Forbes A,Purcell P,Boyd I

更新日期：1993-01-23 00:00:00

abstract：:An investigation was conducted to determine the vehicle of infection of an outbreak of food poisoning in a large metropolitan building early in 1988. A questionnaire was distributed to 700 people who had eaten in the building during the week of the outbreak, and attack rates for specific food were calculated. Food and...

journal_title：BMJ (Clinical research ed.)

authors： Mitchell E,O'Mahony M,Lynch D,Ward LR,Rowe B,Uttley A,Rogers T,Cunningham DG,Watson R

更新日期：1989-01-14 00:00:00

abstract：:The development of a molecular genetics diagnostic service over a three year period was studied in a National Health Service region with a population of three million. Starting from a time when few diagnostic applications were possible, the number of disorders and the overall demand had grown rapidly. Conditions for w...

journal_title：BMJ (Clinical research ed.)

authors： Meredith AL,Upadhyaya M,Harper PS

更新日期：1988-10-01 00:00:00

abstract：:The studyTaylor RS, Walker S, Ciani O, et al. Exercise-based cardiac rehabilitation for chronic heart failure: the EXTRAMATCH II individual participant data meta-analysis. Health Technol Assess 2019;23:1-98.This project was funded by the NIHR Health Technology Assessment Programme (project number 15/80/30).To read the...

journal_title：BMJ (Clinical research ed.)

authors： Cook R,Davidson P,Martin R,NIHR Dissemination Centre.

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To investigate any long term effects of traumatic birth and obstetric procedures in relation to suicide by violent means in offspring as adults. DESIGN:Prospective case-control study. SETTING:Stockholm, Sweden. SUBJECTS:242 adults who committed suicide by violent means from 1978 to 1995, and who were born ...

journal_title：BMJ (Clinical research ed.)

authors： Jacobson B,Bygdeman M

更新日期：1998-11-14 00:00:00

abstract：:Two patients with acute major, disabling cerebral infarction with presumed middle cerebral artery occlusion were treated with the clot specific thrombolytic agent tissue plasminogen activator roughly three and a half hours after the onset of symptoms. Both patients had a normal computed tomography (CT) scan before tre...

journal_title：BMJ (Clinical research ed.)

authors： Koudstaal PJ,Stibbe J,Vermeulen M

更新日期：1988-12-17 00:00:00

abstract：OBJECTIVES:To investigate the perspectives of patients with asthma on the use of an action plan and the implementation of this plan during an asthma attack that culminated in a visit to an emergency department. DESIGN:Qualitative study. SETTING:Tertiary teaching hospital, suburban hospital, and rural hospital. PARTI...

journal_title：BMJ (Clinical research ed.)

authors： Douglass J,Aroni R,Goeman D,Stewart K,Sawyer S,Thien F,Abramson M

更新日期：2002-04-27 00:00:00

abstract：OBJECTIVE:To determine whether short-term, oral low dose prednisolone (< or = 15 mg daily) is superior to placebo and non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis. DESIGN:Meta-analysis of randomised trials of oral corticosteroids compared with placebo or a non-steroidal anti-inflammatory...

journal_title：BMJ (Clinical research ed.)

authors： Gøtzsche PC,Johansen HK

更新日期：1998-03-14 00:00:00

abstract：OBJECTIVE:To determine if sufficient evidence exists to support the use of magnetic resonance angiography as a means of selecting patients with recently symptomatic high grade carotid stenosis for surgery. DESIGN:Systematic review of published research on the diagnostic performance of magnetic resonance angiography, 1...

journal_title：BMJ (Clinical research ed.)

authors： Westwood ME,Kelly S,Berry E,Bamford JM,Gough MJ,Airey CM,Meaney JF,Davies LM,Cullingworth J,Smith MA

更新日期：2002-01-26 00:00:00

abstract：OBJECTIVE:To examine whether the association of inadequate or unclear allocation concealment and lack of blinding with biased estimates of intervention effects varies with the nature of the intervention or outcome. DESIGN:Combined analysis of data from three meta-epidemiological studies based on collections of meta-an...

journal_title：BMJ (Clinical research ed.)

authors： Wood L,Egger M,Gluud LL,Schulz KF,Jüni P,Altman DG,Gluud C,Martin RM,Wood AJ,Sterne JA

更新日期：2008-03-15 00:00:00

abstract：OBJECTIVE:To evaluate the association between use of hormone replacement therapy and the risk of idiopathic venous thromboembolism. DESIGN:Population based case-control study. SETTING:Population enrolled in the General Practice Research Database, United Kingdom. SUBJECTS:A cohort of 347,253 women aged 50 to 79 witho...

journal_title：BMJ (Clinical research ed.)

authors： Pérez Gutthann S,García Rodríguez LA,Castellsague J,Duque Oliart A

更新日期：1997-03-15 00:00:00

abstract：OBJECTIVE:To determine how changes in the number of admissions from waiting lists and changes in the number of additions to the lists are related to list size and waiting times, in the context of local waiting list initiatives. DESIGN:Review of national and Körner statistics. SETTING:England (1987-94) and districts o...

journal_title：BMJ (Clinical research ed.)

authors： Newton JN,Henderson J,Goldacre MJ

更新日期：1995-09-23 00:00:00

abstract：:Aside from email and the world wide web, there are several other systems for distributing information on the Internet. Telnet is a system that allows you to log on to a remote computer from anywhere on the Internet and affords access to many useful biomedical sites on the Internet. File transfer protocol (FTP) is a me...

journal_title：BMJ (Clinical research ed.)

authors： Pallen M

更新日期：1995-12-16 00:00:00

abstract：OBJECTIVE:To determine whether patients with unexpected prehospital cardiac arrest could be identified in whom ambulance resuscitation attempts would be futile. DESIGN:Review of ambulance and hospital records; detailed review of automated external defibrillator rhythm strips of patients in whom no shock was advised. ...

journal_title：BMJ (Clinical research ed.)

authors： Marsden AK,Ng GA,Dalziel K,Cobbe SM

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:To compare the use and effect of a computer based information system for cancer patients that is personalised using each patient's medical record with a system providing only general information and with information provided in booklets. DESIGN:Randomised trial with three groups. Data collected at start of r...

journal_title：BMJ (Clinical research ed.)

authors： Jones R,Pearson J,McGregor S,Cawsey AJ,Barrett A,Craig N,Atkinson JM,Gilmour WH,McEwen J

更新日期：1999-11-06 00:00:00

abstract：OBJECTIVE:To determine whether rates of suicide changed in Toronto after a barrier was erected at Bloor Street Viaduct, the bridge with the world's second highest annual rate of suicide by jumping after Golden Gate Bridge in San Francisco. DESIGN:Natural experiment. SETTING:City of Toronto and province of Ontario, Ca...

journal_title：BMJ (Clinical research ed.)

authors： Sinyor M,Levitt AJ

更新日期：2010-07-06 00:00:00

abstract：OBJECTIVES: To estimate differences in annual income of physicians in the United States by race and sex adjusted for characteristics of physicians and practices. DESIGN: Cross sectional survey study. SETTING: Nationally representative samples of US physicians. PARTICIPANTS: The 2000-13 American Community Survey (ACS...

journal_title：BMJ (Clinical research ed.)

authors： Ly DP,Seabury SA,Jena AB

更新日期：2016-06-07 00:00:00

abstract：OBJECTIVE:To determine the association of resting echocardiography before elective intermediate to high risk non-cardiac surgery with survival and length of hospital stay. DESIGN:Population based retrospective cohort study. SETTING:Acute care hospitals in Ontario, Canada, between 1 April 1999 and 31 March 2008. PART...

journal_title：BMJ (Clinical research ed.)

authors： Wijeysundera DN,Beattie WS,Karkouti K,Neuman MD,Austin PC,Laupacis A

更新日期：2011-06-30 00:00:00

abstract：OBJECTIVE:To determine whether any association exists between exposure to 2009 pandemic H1N1 (pH1N1) influenza vaccination during pregnancy and negative health outcomes in early childhood. DESIGN:Retrospective cohort study. SETTING:Population based birth registry linked with health administrative databases in the pro...

journal_title：BMJ (Clinical research ed.)

authors： Walsh LK,Donelle J,Dodds L,Hawken S,Wilson K,Benchimol EI,Chakraborty P,Guttmann A,Kwong JC,MacDonald NE,Ortiz JR,Sprague AE,Top KA,Walker MC,Wen SW,Fell DB

更新日期：2019-07-10 00:00:00

abstract：OBJECTIVES:To assess heat related mortalities in relation to climate within Europe. DESIGN:Observational population study. SETTING:North Finland, south Finland, Baden-Württemberg, Netherlands, London, north Italy, and Athens. SUBJECTS:People aged 65-74. MAIN OUTCOME MEASURES:Mortalities at temperatures above, below...

journal_title：BMJ (Clinical research ed.)

authors： Keatinge WR,Donaldson GC,Cordioli E,Martinelli M,Kunst AE,Mackenbach JP,Nayha S,Vuori I

更新日期：2000-09-16 00:00:00

abstract：OBJECTIVE:To estimate changes in the risk of autism and assess the relation of autism to the mumps, measles, and rubella (MMR) vaccine. DESIGN:Time trend analysis of data from the UK general practice research database (GPRD). SETTING:General practices in the United Kingdom. SUBJECTS:Children aged 12 years or younger...

journal_title：BMJ (Clinical research ed.)

authors： Kaye JA,del Mar Melero-Montes M,Jick H

更新日期：2001-02-24 00:00:00