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abstract：OBJECTIVES:To estimate survival after a diagnosis of dementia in primary care, compared with people without dementia, and to determine incidence of dementia. DESIGN:Cohort study using data from The Health Improvement Network (THIN), a primary care database. SETTING:353 general practices in the United Kingdom providin...

journal_title：BMJ (Clinical research ed.)

authors： Rait G,Walters K,Bottomley C,Petersen I,Iliffe S,Nazareth I

更新日期：2010-08-05 00:00:00

abstract：:Objective To determine whether educational attainment is a causal risk factor in the development of coronary heart disease.Design Mendelian randomisation study, using genetic data as proxies for education to minimise confounding.Setting The main analysis used genetic data from two large consortia (CARDIoGRAMplusC4D an...

journal_title：BMJ (Clinical research ed.)

authors： Tillmann T,Vaucher J,Okbay A,Pikhart H,Peasey A,Kubinova R,Pajak A,Tamosiunas A,Malyutina S,Hartwig FP,Fischer K,Veronesi G,Palmer T,Bowden J,Davey Smith G,Bobak M,Holmes MV

更新日期：2017-08-30 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of emotionalism after stroke, to assess its relation with other mood disorders, and to identify clinical variables with which it is associated. DESIGN:Descriptive study of a cohort of patients consecutively entered on a community stroke register. SETTING:Community based research p...

journal_title：BMJ (Clinical research ed.)

authors： House A,Dennis M,Molyneux A,Warlow C,Hawton K

更新日期：1989-04-15 00:00:00

abstract：OBJECTIVE:To determine whether a relation between urinary retention and temporal rhythms exists. DESIGN:Retrospective analysis of patients presenting over three years. SETTING:Urology departments in two hospitals. PATIENTS:815 Patients presenting as emergency admissions with urinary retention and requiring immediate...

journal_title：BMJ (Clinical research ed.)

authors： Payne SR,Deardon DJ,Abercrombie GF,Carlson GL

更新日期：1989-12-23 00:00:00

abstract：OBJECTIVE:To evaluate the impact of the US Air Force suicide prevention programme on risk of suicide and other outcomes that share underlying risk factors. DESIGN:Cohort study with quasi-experimental design and analysis of cohorts before (1990-6) and after (1997-2002) the intervention. PARTICIPANTS:5,260,292 US Air F...

journal_title：BMJ (Clinical research ed.)

authors： Knox KL,Litts DA,Talcott GW,Feig JC,Caine ED

更新日期：2003-12-13 00:00:00

abstract：OBJECTIVE:To examine the potential effectiveness and efficiency of different guidelines for statin treatment to reduce deaths from coronary heart disease in the Canadian population. DESIGN:Modelled outcomes of screening and treatment recommendations of six national or international guidelines--from Canada, Australia, ...

journal_title：BMJ (Clinical research ed.)

authors： Manuel DG,Kwong K,Tanuseputro P,Lim J,Mustard CA,Anderson GM,Ardal S,Alter DA,Laupacis A

更新日期：2006-06-17 00:00:00

abstract：OBJECTIVE:To compare neonatal mortality and morbidity in term infants presenting by the breech and delivered vaginally or by caesarean section. DESIGN:Population based comparison of outcomes. Data derived from the St Mary's maternity information system. SETTING:North West Thames Regional Health Authority, 1988-90. S...

journal_title：BMJ (Clinical research ed.)

authors： Thorpe-Beeston JG,Banfield PJ,Saunders NJ

更新日期：1992-09-26 00:00:00

abstract：OBJECTIVE:To systematically determine the impact of growth hormone therapy on adult height of children with idiopathic short stature. DESIGN:Systematic review. DATA SOURCES:Cochrane Central Register of Controlled Trials, Medline, and the bibliographic references from retrieved articles of randomised and non-randomise...

journal_title：BMJ (Clinical research ed.)

authors： Deodati A,Cianfarani S

更新日期：2011-03-11 00:00:00

abstract：OBJECTIVE:To identify and explore parents' concerns when young children become acutely ill. DESIGN:Qualitative study making use of semi-structured one to one and group interviews with parents of preschool children. SETTING:Disadvantaged inner city community. SUBJECTS:95 parents of preschool children. RESULTS:Fever,...

journal_title：BMJ (Clinical research ed.)

authors： Kai J

更新日期：1996-10-19 00:00:00

abstract：:The Swedish government recently published a report on priorities in health care. It was written by a cross party group of politicians and drew extensively on the views of the public, health professionals, experience of earlier local exercises in priority setting, and research based evidence. It laid down an ethical fr...

journal_title：BMJ (Clinical research ed.)

authors： McKee M,Figueras J

更新日期：1996-03-16 00:00:00

abstract：:Polls show increasing public interest in advance statements or directives about medical treatment ("living wills") but that few people, apart from Jehovah's Witnesses, carry such documents. Patients' firm, witnessed oral decisions are often sufficient to aid clinical decision making but should still be recorded in med...

journal_title：BMJ (Clinical research ed.)

authors： Sommerville A

更新日期：1995-06-24 00:00:00

abstract：OBJECTIVE:To compare the prevalence of silent myocardial ischaemia associated with coronary artery disease in diabetic subjects with that in controls of similar age and sex. DESIGN:A controlled study in which subjects with positive findings on exercise electrocardiography, 24 hour electrocardiographic recording, or dy...

journal_title：BMJ (Clinical research ed.)

authors： Koistinen MJ

更新日期：1990-07-14 00:00:00

abstract：OBJECTIVE:To assess the education and workload of preregistration house officers in the four Thames regions. DESIGN:Postal questionnaire. SETTING:Teaching and non-teaching hospitals in the four Thames regions. PARTICIPANTS:1064 Preregistration house officers. RESULTS:Response rate was 70% (740 replies). Nine per ce...

journal_title：BMJ (Clinical research ed.)

authors： Dent TH,Gillard JH,Aarons EJ,Crimlisk HL,Smyth-Pigott PJ

更新日期：1990-03-17 00:00:00

abstract：OBJECTIVE:To assess the ability of radiographers to identify abnormal radiographs of patients attending accident and emergency departments. DESIGN:Prospective study over six weeks. SETTING:Teaching hospital casualty x ray department. PATIENTS:3394 consecutive patients referred for radiography. INTERVENTIONS:Radiogr...

journal_title：BMJ (Clinical research ed.)

authors： Renwick IG,Butt WP,Steele B

更新日期：1991-03-09 00:00:00

abstract：OBJECTIVE:To estimate the usefulness of serum concentrations of the complex of trypsin 2 and alpha 1 antitrypsin in diagnosing and assessing the severity of acute pancreatitis in comparison with serum C reactive protein, amylase, and trypsinogen 2 concentrations (reference markers). DESIGN:Markers were measured in con...

journal_title：BMJ (Clinical research ed.)

authors： Hedström J,Sainio V,Kemppainen E,Haapiainen R,Kivilaakso E,Schröder T,Leinonen J,Stenman UH

更新日期：1996-08-10 00:00:00

abstract：OBJECTIVE:To assess the impact of construction of microdams on the incidence of malaria in nearby communities in terms of possibly increasing peak incidence and prolonging transmission. DESIGN:Four quarterly cycles of malaria incidence surveys, each taking 30 days, undertaken in eight at risk communities close to dams...

journal_title：BMJ (Clinical research ed.)

authors： Ghebreyesus TA,Haile M,Witten KH,Getachew A,Yohannes AM,Yohannes M,Teklehaimanot HD,Lindsay SW,Byass P

更新日期：1999-09-11 00:00:00

abstract：OBJECTIVES:To determine whether informed consent introduces selection bias in prospective observational studies using data from medical records, and consent rates for such studies. DESIGN:Systematic review. DATA SOURCES:Embase, Medline, and the Cochrane Library up to March 2008, reference lists from pertinent article...

journal_title：BMJ (Clinical research ed.)

authors： Kho ME,Duffett M,Willison DJ,Cook DJ,Brouwers MC

更新日期：2009-03-12 00:00:00

abstract：:The right of consultants to study leave and expenses is not binding on trusts and has been eroded in directly managed units. Complaints led to a survey of consultants in North West Thames region. This showed that most consultants use their own time and money to maintain their knowledge by buying and consulting journal...

journal_title：BMJ (Clinical research ed.)

authors： Kerr DN,Jones SA,Easmon CS

更新日期：1993-05-22 00:00:00

abstract：OBJECTIVE:To investigate the long term effects of continuous subcutaneous insulin infusion (insulin pump therapy) on cardiovascular diseases and mortality in people with type 1 diabetes. DESIGN:Observational study. SETTING:Swedish National Diabetes Register, Sweden 2005-12. PARTICIPANTS:18,168 people with type 1 dia...

journal_title：BMJ (Clinical research ed.)

authors： Steineck I,Cederholm J,Eliasson B,Rawshani A,Eeg-Olofsson K,Svensson AM,Zethelius B,Avdic T,Landin-Olsson M,Jendle J,Gudbjörnsdóttir S,Swedish National Diabetes Register.

更新日期：2015-06-22 00:00:00

abstract：OBJECTIVES:To examine the risk of atrial fibrillation in relation to the whole spectrum of thyroid function in a large cohort of patients. DESIGN:Population based cohort study of general practice patients identified by linkage of nationwide registries at the individual level. SETTING:Primary care patients in the city...

journal_title：BMJ (Clinical research ed.)

authors： Selmer C,Olesen JB,Hansen ML,Lindhardsen J,Olsen AM,Madsen JC,Faber J,Hansen PR,Pedersen OD,Torp-Pedersen C,Gislason GH

更新日期：2012-11-27 00:00:00

abstract：OBJECTIVE:To compare perinatal outcomes in births of women with versus without a history of bariatric surgery. DESIGN:Population based matched cohort study. SETTING:Swedish national health service. PARTICIPANTS:1,742,702 singleton births identified in the Swedish medical birth register between 1992 and 2009. For eac...

journal_title：BMJ (Clinical research ed.)

authors： Roos N,Neovius M,Cnattingius S,Trolle Lagerros Y,Sääf M,Granath F,Stephansson O

更新日期：2013-11-12 00:00:00

abstract：OBJECTIVES:To investigate whether routinely collected data from hospital episode statistics could be used to identify the gynaecologist Rodney Ledward, who was suspended in 1966 and was the subject of the Ritchie inquiry into quality and practice within the NHS. DESIGN:A mixed scanning approach was used to identify se...

journal_title：BMJ (Clinical research ed.)

authors： Harley M,Mohammed MA,Hussain S,Yates J,Almasri A

更新日期：2005-04-23 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of dietary antioxidants in the primary prevention of age related macular degeneration (AMD). DESIGN:Systematic review and meta-analysis. DATA SOURCES:Search of seven databases without limits on year or language of publication, and retrieval of references in pertinent reviews an...

journal_title：BMJ (Clinical research ed.)

authors： Chong EW,Wong TY,Kreis AJ,Simpson JA,Guymer RH

更新日期：2007-10-13 00:00:00

abstract：:The studyTaylor RS, Walker S, Ciani O, et al. Exercise-based cardiac rehabilitation for chronic heart failure: the EXTRAMATCH II individual participant data meta-analysis. Health Technol Assess 2019;23:1-98.This project was funded by the NIHR Health Technology Assessment Programme (project number 15/80/30).To read the...

journal_title：BMJ (Clinical research ed.)

authors： Cook R,Davidson P,Martin R,NIHR Dissemination Centre.

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To determine whether any association exists between exposure to 2009 pandemic H1N1 (pH1N1) influenza vaccination during pregnancy and negative health outcomes in early childhood. DESIGN:Retrospective cohort study. SETTING:Population based birth registry linked with health administrative databases in the pro...

journal_title：BMJ (Clinical research ed.)

authors： Walsh LK,Donelle J,Dodds L,Hawken S,Wilson K,Benchimol EI,Chakraborty P,Guttmann A,Kwong JC,MacDonald NE,Ortiz JR,Sprague AE,Top KA,Walker MC,Wen SW,Fell DB

更新日期：2019-07-10 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of health checks by nurses in reducing risk factors for cardiovascular disease in patients from general practice. DESIGN:Randomised controlled trial. SETTING:Five urban general practices in Bedfordshire. SUBJECTS:2136 patients receiving an initial health check in 1989-91 and sch...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1994-01-29 00:00:00

abstract：UNLABELLED:OBJECTIVE-To assess the risk of cardiorespiratory symptoms and mortality in non-smokers who were passively exposed to environmental smoke. DESIGN:Prospective study of cohort from general population first screened between 1972 and 1976 and followed up for an average of 11.5 years, with linkage of data from p...

journal_title：BMJ (Clinical research ed.)

authors： Hole DJ,Gillis CR,Chopra C,Hawthorne VM

更新日期：1989-08-12 00:00:00

abstract：OBJECTIVE:To determine, using research on duloxetine for major depressive disorder as an example, if there are inconsistencies between protocols, clinical study reports, and main publicly available sources (journal articles and trial registries), and within clinical study reports themselves, with respect to benefits an...

journal_title：BMJ (Clinical research ed.)

authors： Maund E,Tendal B,Hróbjartsson A,Jørgensen KJ,Lundh A,Schroll J,Gøtzsche PC

更新日期：2014-06-04 00:00:00

abstract：OBJECTIVE:To assess whether mini flow meters used to measure peak expiratory flow can track changes in lung function and indicate clinically important changes. DESIGN:Comparison of measurements with a spirometer and different brands of mini flow meter; the meters were allocated to subjects haphazardly. SUBJECTS:12 bo...

journal_title：BMJ (Clinical research ed.)

authors： Sly PD,Cahill P,Willet K,Burton P

更新日期：1994-02-26 00:00:00

abstract：OBJECTIVE:To identify historical and clinical findings at emergency department presentation associated with severe H1N1 outcome in children presenting with influenza-like illness. DESIGN:Multicentre retrospective case-control study. SETTING:79 emergency departments of hospitals associated with the Pediatric Emergency...

journal_title：BMJ (Clinical research ed.)

authors： Dalziel SR,Thompson JM,Macias CG,Fernandes RM,Johnson DW,Waisman Y,Cheng N,Acworth J,Chamberlain JM,Osmond MH,Plint A,Valerio P,Black KJ,Fitzpatrick E,Newton AS,Kuppermann N,Klassen TP,Pediatric Emergency Research Netwo

更新日期：2013-08-12 00:00:00