Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study.

abstract：OBJECTIVE:To evaluate the primary care communications initiative, which introduced NHSnet to primary care in Scotland. DESIGN:Semi-structured telephone interviews, postal questionnaire. SETTING:All 15 Scottish health boards, random sample of 1 in 3 of all Scottish general practices. PARTICIPANTS:Information manageme...

journal_title：BMJ (Clinical research ed.)

authors： Willmot M,Sullivan F

更新日期：2000-10-07 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of a teacher led intervention to improve teenagers' knowledge about emergency contraception. DESIGN:Cluster randomised controlled trial. SETTING:24 mixed sex, state secondary schools in Avon, south west England. PARTICIPANTS:1974 boys and 1820 girls in year 10 (14-15 year olds)....

journal_title：BMJ (Clinical research ed.)

authors： Graham A,Moore L,Sharp D,Diamond I

更新日期：2002-05-18 00:00:00

abstract：OBJECTIVE:To conduct a systematic review and meta-analysis of cohort studies of body mass index (BMI) and the risk of all cause mortality, and to clarify the shape and the nadir of the dose-response curve, and the influence on the results of confounding from smoking, weight loss associated with disease, and preclinical...

journal_title：BMJ (Clinical research ed.)

authors： Aune D,Sen A,Prasad M,Norat T,Janszky I,Tonstad S,Romundstad P,Vatten LJ

更新日期：2016-05-04 00:00:00

abstract：OBJECTIVES:To determine general practitioners' responses to and explanations for variation in rates of referral to hospital and how feedback of data on rates of referral could be used to facilitate practices in auditing their own referral behaviour. DESIGN:Visits by audit facilitators to general practices after feedba...

journal_title：BMJ (Clinical research ed.)

authors： de Marco P,Dain C,Lockwood T,Roland M

更新日期：1993-12-04 00:00:00

abstract：OBJECTIVE:To systematically review and describe currently available approaches to supporting maintenance of weight loss in obese adults and to assess the evidence for the effectiveness of these interventions. DESIGN:Systematic review with meta-analysis. DATA SOURCES:Medline, PsycINFO, Embase, and the Cochrane Central...

journal_title：BMJ (Clinical research ed.)

authors： Dombrowski SU,Knittle K,Avenell A,Araújo-Soares V,Sniehotta FF

更新日期：2014-05-14 00:00:00

abstract：OBJECTIVE:To investigate whether residence before and after birth near 50 Hz high voltage installations increases a child's risk of cancer and whether risk correlates with the strength of the magnetic field. DESIGN:A population based case-control study. SETTING:Denmark. SUBJECTS:1707 children under the age of 15 wit...

journal_title：BMJ (Clinical research ed.)

authors： Olsen JH,Nielsen A,Schulgen G

更新日期：1993-10-09 00:00:00

abstract：OBJECTIVE:To assess the effects of preventive home visits to elderly people living in the community. DESIGN:Systematic review. SETTING:15 trials retrieved from Medline, Embase, and the Cochrane controlled trial register. MAIN OUTCOME MEASURES:Physical function, psychosocial function, falls, admissions to institution...

journal_title：BMJ (Clinical research ed.)

authors： van Haastregt JC,Diederiks JP,van Rossum E,de Witte LP,Crebolder HF

更新日期：2000-03-18 00:00:00

abstract：OBJECTIVES:To determine whether over the counter cough medicines are effective for acute cough in adults. DESIGN:Systematic review of randomised controlled trials. DATA SOURCES:Search of the Cochrane Acute Respiratory Infections Group specialised register, Cochrane Controlled Trials Register, Medline, Embase, and the...

journal_title：BMJ (Clinical research ed.)

authors： Schroeder K,Fahey T

更新日期：2002-02-09 00:00:00

abstract：:The aim of community care is to enable people with various types of disability to live in their own homes, rather than in institutions. This involves the provision of support and services at home by various agencies. After a critical report in 1986 identified problems with coordination and flexibility of community car...

journal_title：BMJ (Clinical research ed.)

authors： Renwick D

更新日期：1996-10-05 00:00:00

abstract：OBJECTIVE:To find out what inpatients with advanced cancer who are receiving palliative care think about the effect of thromoprophylaxis on overall quality of life. DESIGN:Qualitative study using audiotaping of semistructured interviews. SETTING:Regional cancer centre in Wales. PARTICIPANTS:28 inpatients with advanc...

journal_title：BMJ (Clinical research ed.)

authors： Noble SI,Nelson A,Turner C,Finlay IG

更新日期：2006-03-11 00:00:00

abstract：OBJECTIVE:To determine whether a decision aid designed for adults with low education and literacy can support informed choice and involvement in decisions about screening for bowel cancer. DESIGN:Randomised controlled trial. SETTING:Areas in New South Wales, Australia identified as socioeconomically disadvantaged (lo...

journal_title：BMJ (Clinical research ed.)

authors： Smith SK,Trevena L,Simpson JM,Barratt A,Nutbeam D,McCaffery KJ

更新日期：2010-10-26 00:00:00

abstract：OBJECTIVE:To investigate the impact of patients' preferences for the treatment of atrial fibrillation, by using individualised decision analysis combining probability and utility assessments into a decision tree. DESIGN:Observational study based on interviews with patients. SETTING:Eight general practices in Avon. P...

journal_title：BMJ (Clinical research ed.)

authors： Protheroe J,Fahey T,Montgomery AA,Peters TJ

更新日期：2000-05-20 00:00:00

abstract：OBJECTIVE:To examine changes in immunisation performance in Grampian region after the introduction of the 1990 contract for general practitioners. DESIGN:Retrospective descriptive study using data held on the Grampian immunisation record system's computer. SETTING:All 95 general practices in Grampian region (313 gene...

journal_title：BMJ (Clinical research ed.)

authors： Ritchie LD,Bisset AF,Russell D,Leslie V,Thomson I

更新日期：1992-03-28 00:00:00

abstract：OBJECTIVES: To estimate differences in annual income of physicians in the United States by race and sex adjusted for characteristics of physicians and practices. DESIGN: Cross sectional survey study. SETTING: Nationally representative samples of US physicians. PARTICIPANTS: The 2000-13 American Community Survey (ACS...

journal_title：BMJ (Clinical research ed.)

authors： Ly DP,Seabury SA,Jena AB

更新日期：2016-06-07 00:00:00

abstract：:An association between vasectomy and the development of testicular tumors, and the importance of testicular examinations both before and after a vasectomy is discussed. Patients diagnosed with testicular tumors within the last ten years were examined at Bangour General Hospital in Scotland. From 1977-87, 37 patients...

journal_title：BMJ (Clinical research ed.)

authors： Cale AR,Farouk M,Prescott RJ,Wallace IW

更新日期：1990-02-10 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of neuromuscular training in reducing the rate of acute knee injury in adolescent female football players. DESIGN:Stratified cluster randomised controlled trial with clubs as the unit of randomisation. SETTING:230 Swedish football clubs (121 in the intervention group, 109 in th...

journal_title：BMJ (Clinical research ed.)

authors： Waldén M,Atroshi I,Magnusson H,Wagner P,Hägglund M

更新日期：2012-05-03 00:00:00

abstract：OBJECTIVE:To study the long term risk of cervical and other cancers after treatment for cervical intraepithelial neoplasia. DESIGN:Retrospective cohort study. SETTING:University Hospital, Helsinki, Finland. PARTICIPANTS:7564 women treated for cervical intraepithelial neoplasia during 1974 and 2001 and followed up th...

journal_title：BMJ (Clinical research ed.)

authors： Kalliala I,Anttila A,Pukkala E,Nieminen P

更新日期：2005-11-19 00:00:00

abstract：OBJECTIVE:To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as an instrument to investigate the causal role of alcohol in cardiovascular disease. DESIGN:Mendelian randomisation meta-analysis of 56 epidemiological studies. PARTICIPANTS:261 991 individuals of European descent, including 20 259 c...

journal_title：BMJ (Clinical research ed.)

authors： Holmes MV,Dale CE,Zuccolo L,Silverwood RJ,Guo Y,Ye Z,Prieto-Merino D,Dehghan A,Trompet S,Wong A,Cavadino A,Drogan D,Padmanabhan S,Li S,Yesupriya A,Leusink M,Sundstrom J,Hubacek JA,Pikhart H,Swerdlow DI,Panayiotou

更新日期：2014-07-10 00:00:00

abstract：OBJECTIVE:To determine cancer morbidity in members of the armed forces who took part in tests of chemical warfare agents from 1941 to 1989. DESIGN:Historical cohort study, with cohort members followed up to December 2004. DATA SOURCE:Archive of UK government research facility at Porton Down, UK military personnel rec...

journal_title：BMJ (Clinical research ed.)

authors： Carpenter LM,Linsell L,Brooks C,Keegan TJ,Langdon T,Doyle P,Maconochie NE,Fletcher T,Nieuwenhuijsen MJ,Beral V,Venables KM

更新日期：2009-03-24 00:00:00

abstract：:Several forces have resulted in the creation in Tayside of the first formally integrated unit of undergraduate and postgraduate education in general practice in the United Kingdom. Forces that helped this integration included the desire for change, national developments in education, financial support through funds se...

journal_title：BMJ (Clinical research ed.)

authors： Bain J,Scott R,Snadden D

更新日期：1995-06-17 00:00:00

abstract：OBJECTIVE:To evaluate the immunogenicity and reactogenicity of a new triple S recombinant hepatitis B vaccine in a cohort of healthy people in whom currently licensed hepatitis B vaccines had persistently not induced an immune response. DESIGN:Single centre, randomised, double blind, dose-response study. SETTING:Rese...

journal_title：BMJ (Clinical research ed.)

authors： Zuckerman JN,Sabin C,Craig FM,Williams A,Zuckerman AJ

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVES:To assess the long term clinical and cost effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) intervention compared with usual care in people with newly diagnosed type 2 diabetes. DESIGN:We undertook a cost-utility analysis that used data from a 12 month, mu...

journal_title：BMJ (Clinical research ed.)

authors： Gillett M,Dallosso HM,Dixon S,Brennan A,Carey ME,Campbell MJ,Heller S,Khunti K,Skinner TC,Davies MJ

更新日期：2010-08-20 00:00:00

abstract：OBJECTIVES:To assess the acceptability of screening newborn boys for Duchenne muscular dystrophy. DESIGN:Screening is offered on the basis of informed consent in response to an information sheet entitled "A new test for baby boys--Do you want it?" The programme includes a prospective long term evaluation of family res...

journal_title：BMJ (Clinical research ed.)

authors： Bradley DM,Parsons EP,Clarke AJ

更新日期：1993-02-06 00:00:00

abstract：OBJECTIVE:To assess the impact of teaching general practitioners to carry out structured assessments of their long term mentally ill patients. DESIGN:Randomised controlled trial. SETTING:Sixteen group general practices in South Thames (west) region. SUBJECTS:440 adults disabled by long term mental illness. INTERVEN...

journal_title：BMJ (Clinical research ed.)

authors： Kendrick T,Burns T,Freeling P

更新日期：1995-07-08 00:00:00

abstract：OBJECTIVES:To investigate the feasibility of obtaining signed consent for submission of patient identifiable data to a national clinical audit database and to identify factors influencing the consent process and its success. DESIGN:Feasibility study. SETTING:Seven paediatric intensive care units in England. PARTICIP...

journal_title：BMJ (Clinical research ed.)

authors： McKinney PA,Jones S,Parslow R,Davey N,Darowski M,Chaudhry B,Stack C,Parry G,Draper ES,PICANet Consent Study Group.

更新日期：2005-04-16 00:00:00

abstract：OBJECTIVES:To investigate the effect of milk supplementation on total body bone mineral acquisition in adolescent girls. DESIGN:18 month, open randomised intervention trial. SUBJECTS:82 white girls aged 12.2 (SD 0.3) years, recruited from four secondary schools in Sheffield. INTERVENTION:568 ml (one pint) of whole o...

journal_title：BMJ (Clinical research ed.)

authors： Cadogan J,Eastell R,Jones N,Barker ME

更新日期：1997-11-15 00:00:00

abstract：OBJECTIVE:To determine patient, institution, and machine characteristics that contribute to variation in radiation doses used for computed tomography (CT). DESIGN:Prospective cohort study. SETTING:Data were assembled and analyzed from the University of California San Francisco CT International Dose Registry. PARTICI...

journal_title：BMJ (Clinical research ed.)

authors： Smith-Bindman R,Wang Y,Chu P,Chung R,Einstein AJ,Balcombe J,Cocker M,Das M,Delman BN,Flynn M,Gould R,Lee RK,Yellen-Nelson T,Schindera S,Seibert A,Starkey J,Suntharalingam S,Wetter A,Wildberger JE,Miglioretti DL

更新日期：2019-01-02 00:00:00

abstract：OBJECTIVES:To evaluate the cardiac safety of central nervous system stimulants in children and adolescents. DESIGN:Population based retrospective cohort study. SETTING:Automated healthcare claims data from 1,219,847 children and young people eligible for 28 state Medicaid programmes from 1999 to 2006 linked to the So...

journal_title：BMJ (Clinical research ed.)

authors： Winterstein AG,Gerhard T,Kubilis P,Saidi A,Linden S,Crystal S,Zito J,Shuster JJ,Olfson M

更新日期：2012-07-18 00:00:00

abstract：OBJECTIVES:To assess aspects of the internal validity of recently published cluster randomised trials and explore the reporting of information useful in assessing the external validity of these trials. DESIGN:Review of 34 cluster randomised trials in primary care published in 2004 and 2005 in seven journals (British M...

journal_title：BMJ (Clinical research ed.)

authors： Eldridge S,Ashby D,Bennett C,Wakelin M,Feder G

更新日期：2008-04-19 00:00:00

abstract：OBJECTIVE:To identify additional factors, such as maternal age or factors related to previous reproductive outcome or family history, and the corresponding probability of carrying a chromosome abnormality in couples with two or more miscarriages. DESIGN:Nested case-control study. SETTING:Six centres for clinical gene...

journal_title：BMJ (Clinical research ed.)

authors： Franssen MT,Korevaar JC,Leschot NJ,Bossuyt PM,Knegt AC,Gerssen-Schoorl KB,Wouters CH,Hansson KB,Hochstenbach R,Madan K,van der Veen F,Goddijn M

更新日期：2005-07-16 00:00:00