Hormone replacement therapy and risk of venous thromboembolism: population based case-control study.

abstract：OBJECTIVE:To study delays between sending referral letters and the outpatient appointment and to assess the content of referral and reply letters, their educational value, and the extent to which questions asked are answered by reply letters. DESIGN:Retrospective review of referrals to 16 consultant orthopaedic surgeo...

journal_title：BMJ (Clinical research ed.)

authors： Jacobs LG,Pringle MA

更新日期：1990-09-08 00:00:00

abstract：OBJECTIVE:To analyse the risk of second primary cancers during long term follow up of patients with Hodgkin's disease. DESIGN:Cohort study. SETTING:The British National Lymphoma Investigation (a collaborative group of over 60 participating centres in Britain treating lymphomas). PATIENTS:2846 patients first treated ...

journal_title：BMJ (Clinical research ed.)

authors： Swerdlow AJ,Douglas AJ,Hudson GV,Hudson BV,Bennett MH,MacLennan KA

更新日期：1992-05-02 00:00:00

abstract：:The disease management approach to patient care seeks to coordinate resources across the healthcare delivery system. The growing interest in evidence based medicine and outcomes, and a commitment to integrated care across the primary, secondary, and community care sectors, all contribute to making disease management a...

journal_title：BMJ (Clinical research ed.)

authors： Hunter DJ,Fairfield G

更新日期：1997-07-05 00:00:00

abstract：:In the absence of any systematic evaluation of the changes it has made to the NHS, the government cites three "indicators of success." These are record numbers of patients treated, shorter waiting times for hospital treatment, and more children being immunised against the main childhood diseases. Closer inspection of ...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1995-04-22 00:00:00

abstract：:The high prevalence of cigarette smoking and tobacco related morbidity and mortality in people with chronic mental illness is well documented. This review summarizes results from studies of smoking cessation treatments in people with schizophrenia, depression, anxiety disorders, and post-traumatic stress disorder. It ...

journal_title：BMJ (Clinical research ed.)

authors： Tidey JW,Miller ME

更新日期：2015-09-21 00:00:00

abstract：OBJECTIVE:To synthesise the views of patients and carers in decision making regarding treatment for chronic kidney disease, and to determine which factors influence those decisions. DESIGN:Systematic review of qualitative studies of decision making and choice for dialysis, transplantation, or palliative care, and them...

journal_title：BMJ (Clinical research ed.)

authors： Morton RL,Tong A,Howard K,Snelling P,Webster AC

更新日期：2010-01-19 00:00:00

abstract：OBJECTIVES:To compare the frequency of discrepancies in retracted reports of clinical trials with those in adjacent unretracted reports in the same journal. DESIGN:Blinded case-control study. SETTING:Journals in PubMed. POPULATION:50 manuscripts, classified on PubMed as retracted clinical trials, paired with 50 adja...

journal_title：BMJ (Clinical research ed.)

authors： Cole GD,Nowbar AN,Mielewczik M,Shun-Shin MJ,Francis DP

更新日期：2015-09-20 00:00:00

abstract：OBJECTIVE:To describe the clinical circumstances in which psychiatric patients commit suicide. DESIGN:National clinical survey. SETTING:England and Wales. SUBJECTS:A two year sample of people who had committed suicide, in particular those who had been in contact with mental health services in the 12 months before de...

journal_title：BMJ (Clinical research ed.)

authors： Appleby L,Shaw J,Amos T,McDonnell R,Harris C,McCann K,Kiernan K,Davies S,Bickley H,Parsons R

更新日期：1999-05-08 00:00:00

abstract：STUDY QUESTION:Does maternal smoking during pregnancy and exposure of infants to tobacco smoke at age 4 months increase the risk of caries in deciduous teeth? METHODS:Population based retrospective cohort study of 76 920 children born between 2004 and 2010 in Kobe City, Japan who received municipal health check-ups at...

journal_title：BMJ (Clinical research ed.)

authors： Tanaka S,Shinzawa M,Tokumasu H,Seto K,Tanaka S,Kawakami K

更新日期：2015-10-21 00:00:00

abstract：OBJECTIVE:To examine the impact of antenatal supplementation with multiple micronutrients or iron and folic acid compared with folic acid alone on birth weight, duration of gestation, and maternal haemoglobin concentration in the third trimester. DESIGN:Cluster randomised double blind controlled trial. SETTING:Two ru...

journal_title：BMJ (Clinical research ed.)

authors： Zeng L,Dibley MJ,Cheng Y,Dang S,Chang S,Kong L,Yan H

更新日期：2008-11-07 00:00:00

abstract：OBJECTIVE:To investigate the risk factors for HIV infection in patients attending clinics for sexually transmitted diseases in India. DESIGN:Descriptive study of HIV serology, risk behaviour, and findings on physical examination. SUBJECTS:2800 patients presenting to outpatient clinics between 13 May 1993 and 15 July ...

journal_title：BMJ (Clinical research ed.)

authors： Rodrigues JJ,Mehendale SM,Shepherd ME,Divekar AD,Gangakhedkar RR,Quinn TC,Paranjape RS,Risbud AR,Brookmeyer RS,Gadkari DA

更新日期：1995-07-29 00:00:00

abstract：:In a series of papers published during the past decade Richard Wilkinson has advanced the view that income inequality is the key determinant of variations in average life expectancy at birth among developed countries. Yet a careful examination of the two sources of data on income distribution most often used by Wilkin...

journal_title：BMJ (Clinical research ed.)

authors： Judge K

更新日期：1995-11-11 00:00:00

abstract：OBJECTIVE:To investigate the association between birth weight of offspring and mortality among fathers and mothers in the west of Scotland. DESIGN:Prospective observational study. PARTICIPANTS:794 married couples in Renfrew district of the west of Scotland. MAIN OUTCOME MEASURES:Mortality from all causes and from ca...

journal_title：BMJ (Clinical research ed.)

authors： Davey Smith G,Hart C,Ferrell C,Upton M,Hole D,Hawthorne V,Watt G

更新日期：1997-11-08 00:00:00

abstract：:Some existing laws and some proposed legislation regulating the practice of in vitro fertilization (IVF) limit its availability to infertile couples. Dawson and Singer question whether it is reasonable to so restrict access to IVF, and examine some of the medical and social circumstances in which IVF and the related ...

journal_title：BMJ (Clinical research ed.)

authors： Dawson K,Singer P

更新日期：1990-01-20 00:00:00

abstract：OBJECTIVE:To investigate whether work related stress, measured and defined as job strain, is associated with the overall risk of cancer and the risk of colorectal, lung, breast, or prostate cancers. DESIGN:Meta-analysis of pooled prospective individual participant data from 12 European cohort studies including 116,056...

journal_title：BMJ (Clinical research ed.)

authors： Heikkilä K,Nyberg ST,Theorell T,Fransson EI,Alfredsson L,Bjorner JB,Bonenfant S,Borritz M,Bouillon K,Burr H,Dragano N,Geuskens GA,Goldberg M,Hamer M,Hooftman WE,Houtman IL,Joensuu M,Knutsson A,Koskenvuo M,Koskinen A

更新日期：2013-02-07 00:00:00

abstract：OBJECTIVES:To develop a systematic method for both summative and formative audit of practice audits, and to use the method to review Oxfordshire practice audits and to plan improvement. DESIGN:Development of a coding system for the audit cycle subsequently used prospectively to assess audits reported to medical audit ...

journal_title：BMJ (Clinical research ed.)

authors： Derry J,Lawrence M,Griew K,Anderson J,Humphreys J,Pandher KS

更新日期：1991-11-16 00:00:00

abstract：OBJECTIVE:To derive and validate an algorithm to estimate the absolute risk of having ovarian cancer in women with and without symptoms. DESIGN:Cohort study with data from 375 UK QResearch general practices for development and 189 for validation. PARTICIPANTS:Women aged 30-84 without a diagnosis of ovarian cancer at ...

journal_title：BMJ (Clinical research ed.)

authors： Hippisley-Cox J,Coupland C

更新日期：2011-01-04 00:00:00

abstract：:The studyA Rodger, V Cambiano, T Bruun, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet 2019;393:2428-38.This project was funde...

journal_title：BMJ (Clinical research ed.)

authors： Cook R,Davidson P,clinical adviser,.,Martin R,NIHR Dissemination Centre.

更新日期：2019-08-27 00:00:00

abstract：OBJECTIVE:To compare neonatal mortality and morbidity in term infants presenting by the breech and delivered vaginally or by caesarean section. DESIGN:Population based comparison of outcomes. Data derived from the St Mary's maternity information system. SETTING:North West Thames Regional Health Authority, 1988-90. S...

journal_title：BMJ (Clinical research ed.)

authors： Thorpe-Beeston JG,Banfield PJ,Saunders NJ

更新日期：1992-09-26 00:00:00

abstract：OBJECTIVE: To compare the effectiveness of flexible sigmoidoscopy in screening for colorectal cancer by patient sex and age. DESIGN: Pooled analysis of randomised trials (the US Prostate, Lung, Colorectal and Ovarian cancer screening trial (PLCO), the Italian Screening for Colon and Rectum trial (SCORE), and the Norwe...

journal_title：BMJ (Clinical research ed.)

authors： Holme Ø,Schoen RE,Senore C,Segnan N,Hoff G,Løberg M,Bretthauer M,Adami HO,Kalager M

更新日期：2017-01-13 00:00:00

abstract：OBJECTIVE:To assess the role of rhinoviruses in elderly people living in the community. DESIGN:Prospective community based surveillance of elderly people, without intervention. Subjects were telephoned weekly to identify symptomatic upper respiratory tract infections. Symptoms and impact of illnesses were monitored, a...

journal_title：BMJ (Clinical research ed.)

authors： Nicholson KG,Kent J,Hammersley V,Cancio E

更新日期：1996-11-02 00:00:00

abstract：OBJECTIVE:To evaluate the incidence of serious maternal complications after the use of various tocolytic drugs for the treatment of preterm labour in routine clinical situations. DESIGN:Prospective cohort study. SETTING:28 hospitals in the Netherlands and Belgium. PARTICIPANTS:1920 consecutive women treated with toc...

journal_title：BMJ (Clinical research ed.)

authors： de Heus R,Mol BW,Erwich JJ,van Geijn HP,Gyselaers WJ,Hanssens M,Härmark L,van Holsbeke CD,Duvekot JJ,Schobben FF,Wolf H,Visser GH

更新日期：2009-03-05 00:00:00

abstract：:The development of a molecular genetics diagnostic service over a three year period was studied in a National Health Service region with a population of three million. Starting from a time when few diagnostic applications were possible, the number of disorders and the overall demand had grown rapidly. Conditions for w...

journal_title：BMJ (Clinical research ed.)

authors： Meredith AL,Upadhyaya M,Harper PS

更新日期：1988-10-01 00:00:00

abstract：:A US organization, Population Action International, is reported in this article to have released findings on the health risks for women in 118 countries. Countries are ranked on 10 indicators, including such indicators as the number of births to women aged under 19 years, the availability of legal abortion, maternal ...

journal_title：BMJ (Clinical research ed.)

authors： Dillner L

更新日期：1995-07-15 00:00:00

abstract：OBJECTIVE:To examine the effect of the method of data display on physician investigators' decisions to stop hypothetical clinical trials for an unplanned statistical analysis. DESIGN:Prospective, mixed model design with variables between subjects and within subjects (repeated measures). SETTING:Comprehensive cancer c...

journal_title：BMJ (Clinical research ed.)

authors： Elting LS,Martin CG,Cantor SB,Rubenstein EB

更新日期：1999-06-05 00:00:00

abstract：OBJECTIVES:To evaluate current processes by which young children presenting with a febrile illness but suspected of having serious bacterial infection are diagnosed and treated, and to develop and test a multivariable model to distinguish serious bacterial infections from self limiting non-bacterial illnesses. Design T...

journal_title：BMJ (Clinical research ed.)

authors： Craig JC,Williams GJ,Jones M,Codarini M,Macaskill P,Hayen A,Irwig L,Fitzgerald DA,Isaacs D,McCaskill M

更新日期：2010-04-20 00:00:00

abstract：:Hepatitis B virus (HBV) is a global health problem that can lead to cirrhosis and hepatocellular carcinoma (HCC). Although HBV vaccination has reduced the prevalence Of HBV infection, the burden of disease remains high. Treatment with antiviral drugs reduces the risk of liver disease and the development of HCC, and it...

journal_title：BMJ (Clinical research ed.)

authors： Sundaram V,Kowdley K

更新日期：2015-10-21 00:00:00

abstract：OBJECTIVE:To investigate the effect of vitamin A supplementation and BCG vaccination at birth in low birthweight neonates. DESIGN:Randomised, placebo controlled, two by two factorial trial. SETTING:Bissau, Guinea-Bissau. PARTICIPANTS:1717 low birthweight neonates born at the national hospital. INTERVENTION:Neonates...

journal_title：BMJ (Clinical research ed.)

authors： Benn CS,Fisker AB,Napirna BM,Roth A,Diness BR,Lausch KR,Ravn H,Yazdanbakhsh M,Rodrigues A,Whittle H,Aaby P

更新日期：2010-03-09 00:00:00

abstract：:I have attempted to adopt the perspective of a patient--albeit one with a rather atypical background--to explore what I want from health research and researchers. This has left me with the impression that health researchers could serve the interests of the public more effectively in a variety of ways, and that they wo...

journal_title：BMJ (Clinical research ed.)

authors： Chalmers I

更新日期：1995-05-20 00:00:00

abstract：:The International AIDS Vaccine Initiative, based in New York, US, was established in 1996 to develop a safe and affordable AIDS vaccine. It is funded by a number of large foundations and charities, the British government, and the World Bank. The Initiative's first 2 large projects, 2 research programs into a vaccine...

journal_title：BMJ (Clinical research ed.)

authors： Matthews H

更新日期：1998-12-05 00:00:00