Polyunsaturated fatty acids in serum and homocysteine concentrations in Japanese men and women: a cross-sectional study.

abstract：BACKGROUND:DNA methylation is an epigenetic phenomenon that can modulate gene function by up or downregulation of gene expression. Vitamin B12 and folate pathways are involved in the production of S-Adenosylmethionine, the universal methyl donor. FINDINGS:Brain vitamin B12 concentration and global DNA methylation was ...

journal_title：Nutrition & metabolism

authors： Fernàndez-Roig S,Lai SC,Murphy MM,Fernandez-Ballart J,Quadros EV

更新日期：2012-05-18 00:00:00

abstract：Background:Elderly people with type 2 diabetes mellitus (T2DM) have an increased risk of diabetes-related microvascular and macrovascular complications, thus diabetic patients with a functioning gastrointestinal tract but without sufficient oral intake require enteral nutrition (EN) formulas to control blood glucose. W...

journal_title：Nutrition & metabolism

authors： Chen CM,Shih CK,Su YJ,Cheang KU,Lo SF,Li SC

更新日期：2019-10-16 00:00:00

abstract：Background:High levels circulating saturated fatty acids are associated with diabetes, obesity and hyperlipidemia. In heart, the accumulation of saturated fatty acids has been determined to play a role in the development of heart failure and diabetic cardiomyopathy. High-density lipoprotein (HDL) has been reported to p...

journal_title：Nutrition & metabolism

authors： Wu KM,Hsu YM,Ying MC,Tsai FJ,Tsai CH,Chung JG,Yang JS,Tang CH,Cheng LY,Su PH,Viswanadha VP,Kuo WW,Huang CY

更新日期：2019-05-28 00:00:00

abstract：BACKGROUND:Cytokines secreted by adipose tissue macrophages (ATMs) significantly alter adipocyte function, inducing inflammatory responses and decreasing insulin sensitivity. However, little relevant information is available regarding the role of microvesicles (MVs) derived from ATMs in macrophage-adipocyte crosstalk. ...

journal_title：Nutrition & metabolism

authors： Zhang Y,Shi L,Mei H,Zhang J,Zhu Y,Han X,Zhu D

更新日期：2015-06-06 00:00:00

abstract：:Although feeding deficits have been reported in snakes and lizards following vomeronasal system disruption, no deficit has been previously reported in a mammal. We tested gray short-tailed opossums with items from four different food categories prior to occluding access to the vomeronasal organ. Preoperatively, opossu...

journal_title：Nutrition & metabolism

authors： Halpern M,Daniels Y,Zuri I

更新日期：2005-02-22 00:00:00

abstract：:Nutritional research in sickle cell disease has been the focus in recent times owing to not only specific nutritional deficiencies, but also the improvements associated with less painful episodes. Though hydroxyurea remains the drug of choice, certain adverse health effects on long term supplementation makes room for ...

journal_title：Nutrition & metabolism

authors： Khan SA,Damanhouri G,Ali A,Khan SA,Khan A,Bakillah A,Marouf S,Al Harbi G,Halawani SH,Makki A

更新日期：2016-08-08 00:00:00

abstract：BACKGROUND:Protein energy malnutrition is commonly associated with immune dysfunctions and is a major factor in susceptibility to infectious diseases. METHODS:In this study, we evaluated the impact of protein energy malnutrition on the capacity of monocytes and macrophages to upregulate arginase, an enzyme associated ...

journal_title：Nutrition & metabolism

authors： Corware K,Yardley V,Mack C,Schuster S,Al-Hassi H,Herath S,Bergin P,Modolell M,Munder M,Müller I,Kropf P

更新日期：2014-10-24 00:00:00

abstract：Background:The resting metabolic rate (RMR) decrease, observed after an obesity reduction therapy is a determinant of a short-time weight regain. Thus, the objective of this study was to evaluate changes in RMR, and the associated hormonal alterations in obese patients with a very low-calorie ketogenic (VLCK)-diet indu...

journal_title：Nutrition & metabolism

authors： Gomez-Arbelaez D,Crujeiras AB,Castro AI,Martinez-Olmos MA,Canton A,Ordoñez-Mayan L,Sajoux I,Galban C,Bellido D,Casanueva FF

更新日期：2018-02-17 00:00:00

abstract：BACKGROUND:Dihydrocapsiate (DCT) is a natural safe food ingredient which is structurally related to capsaicin from chili pepper and is found in the non-pungent pepper strain, CH-19 Sweet. It has been shown to elicit the thermogenic effects of capsaicin but without its gastrointestinal side effects. METHODS:The present...

journal_title：Nutrition & metabolism

authors： Lee TA,Li Z,Zerlin A,Heber D

更新日期：2010-10-06 00:00:00

abstract：OBJECTIVE:Many studies have shown that vegetarian diet has beneficial effects on the prevention of cardiovascular diseases. However, the effect of vegetarian diet on carotid intima-media thickness (IMT), as well as the association between IMT and duration of vegetarian diet, are still unclear. The present study aims to...

journal_title：Nutrition & metabolism

authors： Yang SY,Zhang HJ,Sun SY,Wang LY,Yan B,Liu CQ,Zhang W,Li XJ

更新日期：2011-09-19 00:00:00

abstract：Background:Muscle protein synthesis and muscle net balance plateau after moderate protein ingestion in adults. However, it has been suggested that there is no practical limit to the anabolic response of whole-body net balance to dietary protein. Moreover, limited research has addressed the anabolic response to dietary ...

journal_title：Nutrition & metabolism

authors： Mazzulla M,Volterman KA,Packer JE,Wooding DJ,Brooks JC,Kato H,Moore DR

更新日期：2018-09-24 00:00:00

abstract：UNLABELLED: BACKGROUND:Leptin-deficient ob/ob mice exhibit adipocyte hypertrophy and hyperplasia as well as elevated adipose tissue and systemic inflammation. Multipotent stem cells isolated from adult adipose tissue can differentiate into adipocytes ex vivo and thereby contribute toward increased adipocyte cell numbe...

journal_title：Nutrition & metabolism

authors： Zhou Z,Neupane M,Zhou HR,Wu D,Chang CC,Moustaid-Moussa N,Claycombe KJ

更新日期：2012-12-05 00:00:00

abstract：BACKGROUND:Dehydroepiandrosterone (DHEA) is precursor of sex steroid hormone. We demonstrated that acute DHEA injection to type 1 diabetes model rats induced improvement of hyperglycemia. However, the effect of the combination of DHEA administration and exercise training on insulin resistance is still unclear. This stu...

journal_title：Nutrition & metabolism

authors： Sato K,Iemitsu M,Aizawa K,Mesaki N,Ajisaka R,Fujita S

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Dietary n-3-polyunsaturated fatty acids (n-3-PUFA) have been shown to reduce body weight and fat mass in rodents as well as in humans in one small short-term study. We conducted this controlled randomized dietary trial to test the hypothesis that n-3-PUFA lower body weight and fat mass by reducing appetite a...

journal_title：Nutrition & metabolism

authors： Kratz M,Callahan HS,Yang PY,Matthys CC,Weigle DS

更新日期：2009-05-29 00:00:00

abstract：Background:Diabetic patients are highly vulnerable to hypoxic injury, which is associated with hypoxia induced BNIP3 expression that subsequently activate apoptosis. Our previous research show that Tetramethylpyrazine (TMP), a food flavoring agent, represses the hypoxia induced BNIP3 expression attenuate myocardial apo...

journal_title：Nutrition & metabolism

authors： Liu SP,Shibu MA,Tsai FJ,Hsu YM,Tsai CH,Chung JG,Yang JS,Tang CH,Wang S,Li Q,Huang CY

更新日期：2020-01-31 00:00:00

abstract：:An association between arteriosclerosis and homocysteine (Hcy) was first demonstrated in 1969. Hcy is a sulfur containing amino acid derived from the essential amino acid methionine (Met). Hyperhomocysteinemia (HHcy) was subsequently shown in several age-related pathologies such as osteoporosis, Alzheimer's disease, P...

journal_title：Nutrition & metabolism

authors： Kumar A,Palfrey HA,Pathak R,Kadowitz PJ,Gettys TW,Murthy SN

更新日期：2017-12-22 00:00:00

abstract：BACKGROUND:Adipocyte volume (fat accumulation) and cell number (adipogenesis) is increased in obese individuals. Our objective was the identification of dietary constituents with inhibitory effects on triglyceride formation during adipogenesis. Therefore an in vitro adipose cell assay in murine C3H10 T1/2 cells was dev...

journal_title：Nutrition & metabolism

authors： Warnke I,Goralczyk R,Fuhrer E,Schwager J

更新日期：2011-05-12 00:00:00

abstract：Background:Caloric restriction since birth changes glucose metabolism by the liver in overnight-fasted rats to a fed-like pattern, in which glucose output is large but gluconeogenesis is negligible. It was investigated whether these changes could be a residual effect of the nutritional condition during lactation and wh...

journal_title：Nutrition & metabolism

authors： Yamada LA,Mariano IR,Sabino VLR,Rabassi RS,Bataglini C,Azevedo SCSF,Branquinho NTD,Kurauti MA,Garcia RF,Pedrosa MMD

更新日期：2019-12-12 00:00:00

abstract：: Drug-drug interactions have become an important issue in health care. It is now realized that many drug-drug interactions can be explained by alterations in the metabolic enzymes that are present in the liver and other extra-hepatic tissues. Many of the major pharmacokinetic interactions between drugs are due to hepa...

journal_title：Nutrition & metabolism

authors： Bibi Z

更新日期：2008-10-18 00:00:00

abstract：BACKGROUND:From a health promotion perspective, the use of dietary indices is preferred above single nutrients and foods to evaluate diet quality. Longitudinal research about the association between dietary indices and respectively anthropometric parameters and blood lipids is lacking. The aim of this study was to inve...

journal_title：Nutrition & metabolism

authors： Mertens E,Deforche B,Mullie P,Lefevre J,Charlier R,Knaeps S,Huybrechts I,Clarys P

更新日期：2015-11-19 00:00:00

abstract：Background:The health benefits of dietary fibre (DF) intake on non-alcoholic fatty liver disease (NAFLD) are controversial. Thus, this large cross-sectional study aimed to determine the associations between DF intake and the prevalence of newly-diagnosed NAFLD in a large general population. Methods:A total of 23,529 p...

journal_title：Nutrition & metabolism

authors： Xia Y,Zhang S,Zhang Q,Liu L,Meng G,Wu H,Bao X,Gu Y,Sun S,Wang X,Zhou M,Jia Q,Song K,Wu Q,Niu K,Zhao Y

更新日期：2020-01-13 00:00:00

abstract：BACKGROUND:To study the effects of a pre-germinated brown rice diet (PR) on diabetic neuropathy in streptozotocin (STZ)-induced diabetic rats. METHODS:The effects of a PR diet on diabetic neuropathy in STZ-induced diabetic rats were evaluated and compared with those fed brown rice (BR) or white rice (WR) diets with re...

journal_title：Nutrition & metabolism

authors： Usuki S,Ito Y,Morikawa K,Kise M,Ariga T,Rivner M,Yu RK

更新日期：2007-11-23 00:00:00

abstract：Background:Trehalose is well known as a functional disaccharide with anti-metabolic activities such as suppression of adipocyte hypertrophy in mice and alleviation of impaired glucose tolerance in humans. Recently, a new type of adipocyte beige cells, involved in so-called white adipocyte tissue (WAT) browning, has rec...

journal_title：Nutrition & metabolism

authors： Arai C,Arai N,Arai S,Yoshizane C,Miyata S,Mizote A,Suyama A,Endo S,Ariyasu T,Mitsuzumi H,Ushio S

更新日期：2019-07-16 00:00:00

abstract：BACKGROUND:Management of glioblastoma multiforme (GBM) has been difficult using standard therapy (radiation with temozolomide chemotherapy). The ketogenic diet is used commonly to treat refractory epilepsy in children and, when administered in restricted amounts, can also target energy metabolism in brain tumors. We re...

journal_title：Nutrition & metabolism

authors： Zuccoli G,Marcello N,Pisanello A,Servadei F,Vaccaro S,Mukherjee P,Seyfried TN

更新日期：2010-04-22 00:00:00

abstract：: Sphingomyelin synthase (SMS) sits at the crossroads of sphingomyelin (SM), ceramide, diacylglycerol (DAG) metabolism. It utilizes ceramide and phosphatidylcholine as substrates to produce SM and DAG, thereby regulating lipid messengers which play a role in cell survival and apoptosis. Furthermore, its product SM has ...

journal_title：Nutrition & metabolism

authors： Yeang C,Ding T,Chirico WJ,Jiang XC

更新日期：2011-12-14 00:00:00

abstract：BACKGROUND:Holotranscobalamin, cobalamin-saturated transcobalamin, is the minor fraction of circulating cobalamin (vitamin B12), which is available for cellular uptake and hence is physiologically relevant. Currently, no method allows simple, direct quantification of holotranscobalamin. We now report on the identificat...

journal_title：Nutrition & metabolism

authors： Orning L,Rian A,Campbell A,Brady J,Fedosov SN,Bramlage B,Thompson K,Quadros EV

更新日期：2006-01-04 00:00:00

abstract：BACKGROUND:Secreted frizzled-related protein 5 (SFRP5) is an anti-inflammatory adipokine modulating metabolism dysfunction. This study aims to observe the effect of recombinant SFRP5 protein on nonalcoholic steatohepatitis (NASH). METHODS:We set up a prokaryotic expression system and purified the recombinant SFRP5 pro...

journal_title：Nutrition & metabolism

authors： Chen L,Zhao X,Liang G,Sun J,Lin Z,Hu R,Chen P,Zhang Z,Zhou L,Li Y

更新日期：2017-08-15 00:00:00

abstract：BACKGROUND:The alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio is reportedly associated with insulin resistance (IR). However, few studies have explored the relationship between the ALT/AST ratio and IR in the Chinese population. Here, we aimed to explore whether the ALT/AST ratio is associated an...

journal_title：Nutrition & metabolism

authors： Zhao L,Cheng J,Chen Y,Li Q,Han B,Chen Y,Xia F,Chen C,Lin D,Yu X,Wang N,Lu Y

更新日期：2017-10-10 00:00:00

abstract：UNLABELLED: BACKGROUND:It is difficult to study the mechanisms of the metabolic syndrome in humans due to the heterogeneous genetic background and lifestyle. The present study investigated changes in the gene and protein profiles in an animal model of the metabolic syndrome to identify the molecular targets associated...

journal_title：Nutrition & metabolism

authors： Chang J,Oikawa S,Ichihara G,Nanpei Y,Hotta Y,Yamada Y,Tada-Oikawa S,Iwahashi H,Kitagawa E,Takeuchi I,Yuda M,Ichihara S

更新日期：2012-09-21 00:00:00

abstract：: Calorie restriction (CR; ~60% of ad libitum, AL intake) has been associated with substantial alterations in body composition and insulin sensitivity. Recently, several proteins that are secreted by nontraditional endocrine tissues, including skeletal muscle and other tissues, have been discovered to modulate energy m...

journal_title：Nutrition & metabolism

authors： Sharma N,Castorena CM,Cartee GD

更新日期：2012-10-15 00:00:00