The metabolism and significance of homocysteine in nutrition and health.

abstract：UNLABELLED:Insufficient calcium intake has been proposed to cause unbalanced energy partitioning leading to obesity. However, weight loss interventions including dietary calcium or dairy product consumption have not reported changes in lipid metabolism measured by the plasma lipidome. METHODS:The objective of this stu...

journal_title：Nutrition & metabolism

authors： Smilowitz JT,Wiest MM,Teegarden D,Zemel MB,German JB,Van Loan MD

更新日期：2011-10-05 00:00:00

abstract：: Prior to the discovery of medical treatment for diabetes, carbohydrate-restriction was the predominant treatment recommendation to treat diabetes mellitus. In this commentary we argue that carbohydrate-restriction should be reincorporated into contemporary treatment studies for diabetes mellitus. ...

journal_title：Nutrition & metabolism

authors： Westman EC,Vernon MC

更新日期：2008-04-09 00:00:00

abstract：BACKGROUND:Secreted frizzled-related protein 5 (SFRP5) is an anti-inflammatory adipokine modulating metabolism dysfunction. This study aims to observe the effect of recombinant SFRP5 protein on nonalcoholic steatohepatitis (NASH). METHODS:We set up a prokaryotic expression system and purified the recombinant SFRP5 pro...

journal_title：Nutrition & metabolism

authors： Chen L,Zhao X,Liang G,Sun J,Lin Z,Hu R,Chen P,Zhang Z,Zhou L,Li Y

更新日期：2017-08-15 00:00:00

abstract：BACKGROUND:Amino acid availability stimulates protein synthesis via the mTORC1 (mechanistic target of rapamycin complex 1) signaling pathway. In response to an increase in cellular amino acid availability, translocation of cytosolic mTORC1 to the lysosomal surface is required to stimulate mTORC1 kinase activity. Howeve...

journal_title：Nutrition & metabolism

authors： Graber TG,Borack MS,Reidy PT,Volpi E,Rasmussen BB

更新日期：2017-05-11 00:00:00

abstract：BACKGROUND:The objective of this study was to describe the intake of macronutrient, especially fatty acids, and explore their possible effect on diabetic retinopathy (DR) in patients with type 2 diabetes mellitus. METHODS:In this case-control study, we included a total of 146 patients with DR and 148 without DR. The i...

journal_title：Nutrition & metabolism

authors： Alcubierre N,Navarrete-Muñoz EM,Rubinat E,Falguera M,Valls J,Traveset A,Vilanova MB,Marsal JR,Hernandez M,Granado-Casas M,Martinez-Gonzalez D,Jurjo C,Franch-Nadal J,Vioque J,Mauricio D

更新日期：2016-06-04 00:00:00

abstract：BACKGROUND:Supplementation studies have suggested a role of n-3 polyunsaturated fatty acids (PUFAs) in homocysteine metabolism, but the evidence is limited and inconsistent among studies that measured blood levels of n-3 and n-6 PUFAs. We examined the association between blood levels of PUFAs and homocysteine in Japane...

journal_title：Nutrition & metabolism

authors： Kume A,Kurotani K,Sato M,Ejima Y,Pham NM,Nanri A,Kuwahara K,Mizoue T

更新日期：2013-06-10 00:00:00

abstract：BACKGROUND:Fasting is a rigorous type of dietary restriction that is associate with a number of health benefits. During fasting, ketone bodies significantly increase in blood and become major body fuels, thereby sparing glucose. In the present study, we investigated effects of fasting on hypersensitivity. In addition, ...

journal_title：Nutrition & metabolism

authors： Nakamura S,Hisamura R,Shimoda S,Shibuya I,Tsubota K

更新日期：2014-08-28 00:00:00

abstract：BACKGROUND:Omega-3 polyunsaturated fatty acids (n-3 PUFA) have been shown to alleviate the symptoms of metabolic disorders, such as heart disease, diabetes, obesity and insulin resistance. Several putative mechanisms by which n-3 PUFA elicit beneficial health effects have been proposed; however, there is still a shorta...

journal_title：Nutrition & metabolism

authors： Ahmed AA,Balogun KA,Bykova NV,Cheema SK

更新日期：2014-01-17 00:00:00

abstract：: Microsomal triglyceride transfer protein (MTP) was first identified as a major cellular protein capable of transferring neutral lipids between membrane vesicles. Its role as an essential chaperone for the biosynthesis of apolipoprotein B (apoB)-containing triglyceride-rich lipoproteins was established after the reali...

journal_title：Nutrition & metabolism

authors： Hussain MM,Rava P,Walsh M,Rana M,Iqbal J

更新日期：2012-02-21 00:00:00

abstract：UNLABELLED: BACKGROUND:Leptin-deficient ob/ob mice exhibit adipocyte hypertrophy and hyperplasia as well as elevated adipose tissue and systemic inflammation. Multipotent stem cells isolated from adult adipose tissue can differentiate into adipocytes ex vivo and thereby contribute toward increased adipocyte cell numbe...

journal_title：Nutrition & metabolism

authors： Zhou Z,Neupane M,Zhou HR,Wu D,Chang CC,Moustaid-Moussa N,Claycombe KJ

更新日期：2012-12-05 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) is frequently associated with hypovitaminosis D. Vitamin D is endowed with pleiotropic effects, including insulin resistance (IR) and apoptotic pathway. Disruption of the complex mechanism that regulated ovarian apoptosis has been reported in PCOS. Phosphoprotein enriched in ...

journal_title：Nutrition & metabolism

authors： Savastano S,Valentino R,Di Somma C,Orio F,Pivonello C,Passaretti F,Brancato V,Formisano P,Colao A,Beguinot F,Tarantino G

更新日期：2011-11-23 00:00:00

abstract：UNLABELLED: BACKGROUND:It has been suggested that Sorghum, a rich source of phytochemicals, has a hypoglycemic effect, but the mechanism is unknown. We investigated the effects of oral administration of sorghum extract (SE) on hepatic gluconeogenesis and the glucose uptake of muscle in streptozotocin-induced diabetic ...

journal_title：Nutrition & metabolism

authors： Kim J,Park Y

更新日期：2012-11-27 00:00:00

abstract：Background:Consumption of diet high in soy products is suggested to contribute to lower prostate cancer incidence in Asian men. But little has been known about the influences of dietary patterns on gut microbiota and microbiota-mediated isoflavone metabolism. Here, we determined the influences of western pattern diet o...

journal_title：Nutrition & metabolism

authors： Liu Y,Wu X,Jiang H

更新日期：2019-04-11 00:00:00

abstract：OBJECTIVE:Many studies have shown that vegetarian diet has beneficial effects on the prevention of cardiovascular diseases. However, the effect of vegetarian diet on carotid intima-media thickness (IMT), as well as the association between IMT and duration of vegetarian diet, are still unclear. The present study aims to...

journal_title：Nutrition & metabolism

authors： Yang SY,Zhang HJ,Sun SY,Wang LY,Yan B,Liu CQ,Zhang W,Li XJ

更新日期：2011-09-19 00:00:00

abstract：BACKGROUND:Adipocyte volume (fat accumulation) and cell number (adipogenesis) is increased in obese individuals. Our objective was the identification of dietary constituents with inhibitory effects on triglyceride formation during adipogenesis. Therefore an in vitro adipose cell assay in murine C3H10 T1/2 cells was dev...

journal_title：Nutrition & metabolism

authors： Warnke I,Goralczyk R,Fuhrer E,Schwager J

更新日期：2011-05-12 00:00:00

abstract：: A large volume of human clinical data supports increased dietary protein for favorable changes to body composition, but not all data are conclusive. The aim of this review is to propose two theories, "protein spread theory" and "protein change theory" in an effort to explain discrepancies in the literature. Protein s...

journal_title：Nutrition & metabolism

authors： Bosse JD,Dixon BM

更新日期：2012-09-12 00:00:00

abstract：BACKGROUND:The conjugated linoleic acid (CLA) content of beef can be increased by supplementing appropriate beef cattle diets with vegetable oil or oil seed. Yet the effect of consumption of such beef on adipose tissue characteristics is unclear, thus the study was conducted to compare adipose tissue responses of rats ...

journal_title：Nutrition & metabolism

authors： He ML,Mir PS,Okine EK,Napadajlo H

更新日期：2009-04-22 00:00:00

abstract：:We studied the regulation of brain acetyl CoA carboxylase (ACC) activity during food deprivation and under the influence of hormones of glucose homeostasis: glucagon and insulin. Mice were deprived of food and water for time periods of 1, 3, 6, 9, 12 and 24 hours and were then allowed to re-feed for 5, 30 and 60 minut...

journal_title：Nutrition & metabolism

authors： Karami KJ,Coppola J,Krishnamurthy K,Llanos DJ,Mukherjee A,Venkatachalam KV

更新日期：2006-02-16 00:00:00

abstract：BACKGROUND:The alanine aminotransferase (ALT)/aspartate aminotransferase (AST) ratio is reportedly associated with insulin resistance (IR). However, few studies have explored the relationship between the ALT/AST ratio and IR in the Chinese population. Here, we aimed to explore whether the ALT/AST ratio is associated an...

journal_title：Nutrition & metabolism

authors： Zhao L,Cheng J,Chen Y,Li Q,Han B,Chen Y,Xia F,Chen C,Lin D,Yu X,Wang N,Lu Y

更新日期：2017-10-10 00:00:00

abstract：: Calorie restriction (CR; ~60% of ad libitum, AL intake) has been associated with substantial alterations in body composition and insulin sensitivity. Recently, several proteins that are secreted by nontraditional endocrine tissues, including skeletal muscle and other tissues, have been discovered to modulate energy m...

journal_title：Nutrition & metabolism

authors： Sharma N,Castorena CM,Cartee GD

更新日期：2012-10-15 00:00:00

abstract：:There has been intense interest in defining the functions of UCP2 and UCP3 during the nine years since the cloning of these UCP1 homologues. Current data suggest that both UCP2 and UCP3 proteins share some features with UCP1, such as the ability to reduce mitochondrial membrane potential, but they also have distinctly...

journal_title：Nutrition & metabolism

authors： Fisler JS,Warden CH

更新日期：2006-09-12 00:00:00

abstract：BACKGROUND:Dehydroepiandrosterone (DHEA) is precursor of sex steroid hormone. We demonstrated that acute DHEA injection to type 1 diabetes model rats induced improvement of hyperglycemia. However, the effect of the combination of DHEA administration and exercise training on insulin resistance is still unclear. This stu...

journal_title：Nutrition & metabolism

authors： Sato K,Iemitsu M,Aizawa K,Mesaki N,Ajisaka R,Fujita S

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:To study the effects of a pre-germinated brown rice diet (PR) on diabetic neuropathy in streptozotocin (STZ)-induced diabetic rats. METHODS:The effects of a PR diet on diabetic neuropathy in STZ-induced diabetic rats were evaluated and compared with those fed brown rice (BR) or white rice (WR) diets with re...

journal_title：Nutrition & metabolism

authors： Usuki S,Ito Y,Morikawa K,Kise M,Ariga T,Rivner M,Yu RK

更新日期：2007-11-23 00:00:00

abstract：Background:Caloric restriction since birth changes glucose metabolism by the liver in overnight-fasted rats to a fed-like pattern, in which glucose output is large but gluconeogenesis is negligible. It was investigated whether these changes could be a residual effect of the nutritional condition during lactation and wh...

journal_title：Nutrition & metabolism

authors： Yamada LA,Mariano IR,Sabino VLR,Rabassi RS,Bataglini C,Azevedo SCSF,Branquinho NTD,Kurauti MA,Garcia RF,Pedrosa MMD

更新日期：2019-12-12 00:00:00

abstract：Background:Visceral adipose tissue (VAT) area is a strong predictor of obesity-related cardiometabolic alterations, but its measurement is costly, time consuming and, in some cases, involves radiation exposure. Glutamate, a by-product of branched-chain-amino-acid (BCAA) catabolism, has been shown to be increased in vis...

journal_title：Nutrition & metabolism

authors： Maltais-Payette I,Boulet MM,Prehn C,Adamski J,Tchernof A

更新日期：2018-11-06 00:00:00

abstract：Background:To examine the impact of changes in all lipid measures including total cholesterol (TC), log-transformed triglycerides (Ln-TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), non-HDL-C, TC/HDL-C and Ln TG/HDL-C, over an approximate 3 year duration, on incident type...

journal_title：Nutrition & metabolism

authors： Khaloo P,Hasheminia M,Tohidi M,Abdi H,Mansournia MA,Azizi F,Hadaegh F

更新日期：2018-07-11 00:00:00

abstract：BACKGROUND:Currently, there is a lack of studies examining the effects of adenosine-5'-triphosphate (ATP) supplementation utilizing a long-term, periodized resistance-training program (RT) in resistance-trained populations. Therefore, we investigated the effects of 12 weeks of 400 mg per day of oral ATP on muscular ada...

journal_title：Nutrition & metabolism

authors： Wilson JM,Joy JM,Lowery RP,Roberts MD,Lockwood CM,Manninen AH,Fuller JC,De Souza EO,Baier SM,Wilson SM,Rathmacher JA

更新日期：2013-09-22 00:00:00

abstract：BACKGROUND:Protein energy malnutrition is commonly associated with immune dysfunctions and is a major factor in susceptibility to infectious diseases. METHODS:In this study, we evaluated the impact of protein energy malnutrition on the capacity of monocytes and macrophages to upregulate arginase, an enzyme associated ...

journal_title：Nutrition & metabolism

authors： Corware K,Yardley V,Mack C,Schuster S,Al-Hassi H,Herath S,Bergin P,Modolell M,Munder M,Müller I,Kropf P

更新日期：2014-10-24 00:00:00

abstract：Background:It is not clear whether the frequently reported phenomenon of exercise-induced anorexia is exacerbated or blunted in warm or cold environments. Therefore, this study investigated the effects of exercise in three different environmental temperatures vs. rest, on perceptions of appetite, appetite regulating ho...

journal_title：Nutrition & metabolism

authors： Mandic I,Ahmed M,Rhind S,Goodman L,L'Abbe M,Jacobs I

更新日期：2019-05-06 00:00:00

abstract：BACKGROUND:DNA methylation is an epigenetic phenomenon that can modulate gene function by up or downregulation of gene expression. Vitamin B12 and folate pathways are involved in the production of S-Adenosylmethionine, the universal methyl donor. FINDINGS:Brain vitamin B12 concentration and global DNA methylation was ...

journal_title：Nutrition & metabolism

authors： Fernàndez-Roig S,Lai SC,Murphy MM,Fernandez-Ballart J,Quadros EV

更新日期：2012-05-18 00:00:00