Has carbohydrate-restriction been forgotten as a treatment for diabetes mellitus? A perspective on the ACCORD study design.

abstract：Background:The health benefits of dietary fibre (DF) intake on non-alcoholic fatty liver disease (NAFLD) are controversial. Thus, this large cross-sectional study aimed to determine the associations between DF intake and the prevalence of newly-diagnosed NAFLD in a large general population. Methods:A total of 23,529 p...

journal_title：Nutrition & metabolism

authors： Xia Y,Zhang S,Zhang Q,Liu L,Meng G,Wu H,Bao X,Gu Y,Sun S,Wang X,Zhou M,Jia Q,Song K,Wu Q,Niu K,Zhao Y

更新日期：2020-01-13 00:00:00

abstract：BACKGROUND:Glutathione has a wide range of functions; it is an endogenous anti-oxidant and plays a key role in the maintenance of intracellular redox balance and detoxification of xenobiotics. Several studies have indicated that children with autism spectrum disorders may have altered glutathione metabolism which could...

journal_title：Nutrition & metabolism

authors： Main PA,Angley MT,O'Doherty CE,Thomas P,Fenech M

更新日期：2012-04-24 00:00:00

abstract：:Although feeding deficits have been reported in snakes and lizards following vomeronasal system disruption, no deficit has been previously reported in a mammal. We tested gray short-tailed opossums with items from four different food categories prior to occluding access to the vomeronasal organ. Preoperatively, opossu...

journal_title：Nutrition & metabolism

authors： Halpern M,Daniels Y,Zuri I

更新日期：2005-02-22 00:00:00

abstract：BACKGROUND:Sub-optimally nourished rats show reduced growth, biochemical and physiological changes. However, no one has assessed metabolic rate adaptations in rats subjected to chronic suboptimal nutrition (CSN). In this study energy expenditure (EE; kcal/100 g body weight) and physical activity (PA; oscillations in we...

journal_title：Nutrition & metabolism

authors： Rising R,Lifshitz F

更新日期：2006-01-31 00:00:00

abstract：BACKGROUND:Management of glioblastoma multiforme (GBM) has been difficult using standard therapy (radiation with temozolomide chemotherapy). The ketogenic diet is used commonly to treat refractory epilepsy in children and, when administered in restricted amounts, can also target energy metabolism in brain tumors. We re...

journal_title：Nutrition & metabolism

authors： Zuccoli G,Marcello N,Pisanello A,Servadei F,Vaccaro S,Mukherjee P,Seyfried TN

更新日期：2010-04-22 00:00:00

abstract：:OBJECTIVE: To compare the effects of isocaloric, energy-restricted very low-carbohydrate ketogenic (VLCK) and low-fat (LF) diets on weight loss, body composition, trunk fat mass, and resting energy expenditure (REE) in overweight/obese men and women. DESIGN: Randomized, balanced, two diet period clinical intervention ...

journal_title：Nutrition & metabolism

authors： Volek J,Sharman M,Gómez A,Judelson D,Rubin M,Watson G,Sokmen B,Silvestre R,French D,Kraemer W

更新日期：2004-11-08 00:00:00

abstract：Background:Zinc deficiency can change the concentrations of minerals and trace elements in the body. However, previous studies still had many limitations. Objective:To reveal the effects of zinc deficiency on homeostasis of 16 minerals and trace elements. Methods:Forty-five rats were divided randomly into three group...

journal_title：Nutrition & metabolism

authors： Yu Q,Sun X,Zhao J,Zhao L,Chen Y,Fan L,Li Z,Sun Y,Wang M,Wang F

更新日期：2019-10-30 00:00:00

abstract：BACKGROUND:Currently, there is a lack of studies examining the effects of adenosine-5'-triphosphate (ATP) supplementation utilizing a long-term, periodized resistance-training program (RT) in resistance-trained populations. Therefore, we investigated the effects of 12 weeks of 400 mg per day of oral ATP on muscular ada...

journal_title：Nutrition & metabolism

authors： Wilson JM,Joy JM,Lowery RP,Roberts MD,Lockwood CM,Manninen AH,Fuller JC,De Souza EO,Baier SM,Wilson SM,Rathmacher JA

更新日期：2013-09-22 00:00:00

abstract：Background:To investigate the association between different obesity phenotypes and the risk of incident hypertension among both genders. Methods:The study population included 3659 Iranians (men = 1540), aged ≥20 years free of hypertension at baseline. Participants were classified into six categories of body mass index...

journal_title：Nutrition & metabolism

authors： Kabootari M,Akbarpour S,Azizi F,Hadaegh F

更新日期：2019-02-27 00:00:00

abstract：Background:It is well known that ingestion of protein sources can stimulate muscle protein synthesis (MPS). The intake of whey protein is highly effective especially for accelerating MPS. Whey protein hydrolysate (WPH) can raise postprandial plasma concentration of amino acids, which impact stimulation of MPS more rapi...

journal_title：Nutrition & metabolism

authors： Nakayama K,Tagawa R,Saito Y,Sanbongi C

更新日期：2019-12-27 00:00:00

abstract：Background:We previously reported on the anti-obesogenic and anti-inflammatory effects associated with n-3 long-chain polyunsaturated fatty acids (LCPUFA) in our diet-induced obesity (DIO) mouse model. Two isocaloric high-fat diets (HFDs; 48 kJ% fat), HFD (HF) and n-3 LCPUFA-enriched HFD (HF/n-3), and a control diet (C...

journal_title：Nutrition & metabolism

authors： Worsch S,Heikenwalder M,Hauner H,Bader BL

更新日期：2018-09-26 00:00:00

abstract：BACKGROUND:Increasing evidence suggests that diets high in polyunsaturated fatty acids (PUFA) confer health benefits by improving insulin sensitivity and lipid metabolism in liver, muscle and adipose tissue. METHODS:The present study investigates metabolic responses in two different lines of mice either selected for h...

journal_title：Nutrition & metabolism

authors： Nuernberg K,Breier BH,Jayasinghe SN,Bergmann H,Thompson N,Nuernberg G,Dannenberger D,Schneider F,Renne U,Langhammer M,Huber K

更新日期：2011-08-11 00:00:00

abstract：Background:Diet and exercise play important roles in ameliorating metabolic syndrome. Yunkang 10 (Camellia sinensis var. assamica) is a most cultivated tea variety for making tea in the Southwestern China. Currently, there is no report of healthy effects of Yunkang 10 green tea (YKGT) and treadmill exercise (Ex) on hig...

journal_title：Nutrition & metabolism

authors： Zhang Y,Gu M,Wang R,Li M,Li D,Xie Z

更新日期：2020-02-04 00:00:00

abstract：BACKGROUND:Adipocyte volume (fat accumulation) and cell number (adipogenesis) is increased in obese individuals. Our objective was the identification of dietary constituents with inhibitory effects on triglyceride formation during adipogenesis. Therefore an in vitro adipose cell assay in murine C3H10 T1/2 cells was dev...

journal_title：Nutrition & metabolism

authors： Warnke I,Goralczyk R,Fuhrer E,Schwager J

更新日期：2011-05-12 00:00:00

abstract：Background:Diabetic patients are highly vulnerable to hypoxic injury, which is associated with hypoxia induced BNIP3 expression that subsequently activate apoptosis. Our previous research show that Tetramethylpyrazine (TMP), a food flavoring agent, represses the hypoxia induced BNIP3 expression attenuate myocardial apo...

journal_title：Nutrition & metabolism

authors： Liu SP,Shibu MA,Tsai FJ,Hsu YM,Tsai CH,Chung JG,Yang JS,Tang CH,Wang S,Li Q,Huang CY

更新日期：2020-01-31 00:00:00

abstract：Background:The evidence on the impact of high sugar consumption on micronutrient dilution does not yet allow for the establishment of clear thresholds of consumption. To establish upper and lower limit intake thresholds for added sugar, more studies from different countries and multiple populations are needed. The aim ...

journal_title：Nutrition & metabolism

authors： González-Padilla E,A Dias J,Ramne S,Olsson K,Nälsén C,Sonestedt E

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND:Dehydroepiandrosterone (DHEA) is precursor of sex steroid hormone. We demonstrated that acute DHEA injection to type 1 diabetes model rats induced improvement of hyperglycemia. However, the effect of the combination of DHEA administration and exercise training on insulin resistance is still unclear. This stu...

journal_title：Nutrition & metabolism

authors： Sato K,Iemitsu M,Aizawa K,Mesaki N,Ajisaka R,Fujita S

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Recent data from this laboratory suggest that components of dairy foods may serve as activators of SIRT1 (Silent Information Regulator Transcript 1), and thereby participate in regulation of glucose and lipid metabolism. In this study, an ex-vivo/in-vitro approach was used to examine the integrated effects o...

journal_title：Nutrition & metabolism

authors： Bruckbauer A,Zemel MB

更新日期：2011-12-20 00:00:00

abstract：BACKGROUND:Fasting is a rigorous type of dietary restriction that is associate with a number of health benefits. During fasting, ketone bodies significantly increase in blood and become major body fuels, thereby sparing glucose. In the present study, we investigated effects of fasting on hypersensitivity. In addition, ...

journal_title：Nutrition & metabolism

authors： Nakamura S,Hisamura R,Shimoda S,Shibuya I,Tsubota K

更新日期：2014-08-28 00:00:00

abstract：UNLABELLED: BACKGROUND:It is difficult to study the mechanisms of the metabolic syndrome in humans due to the heterogeneous genetic background and lifestyle. The present study investigated changes in the gene and protein profiles in an animal model of the metabolic syndrome to identify the molecular targets associated...

journal_title：Nutrition & metabolism

authors： Chang J,Oikawa S,Ichihara G,Nanpei Y,Hotta Y,Yamada Y,Tada-Oikawa S,Iwahashi H,Kitagawa E,Takeuchi I,Yuda M,Ichihara S

更新日期：2012-09-21 00:00:00

abstract：BACKGROUND:Amino acid availability stimulates protein synthesis via the mTORC1 (mechanistic target of rapamycin complex 1) signaling pathway. In response to an increase in cellular amino acid availability, translocation of cytosolic mTORC1 to the lysosomal surface is required to stimulate mTORC1 kinase activity. Howeve...

journal_title：Nutrition & metabolism

authors： Graber TG,Borack MS,Reidy PT,Volpi E,Rasmussen BB

更新日期：2017-05-11 00:00:00

abstract：BACKGROUND:Two major risk factors for the onset of fatty liver disease are excessive alcohol intake and obesity, the latter being associated with non-alcoholic fatty liver disease (NAFLD). The aim of this study was to examine the effects of black rice extract (BRE) on hepatic steatosis and insulin resistance in high-fa...

journal_title：Nutrition & metabolism

authors： Jang HH,Park MY,Kim HW,Lee YM,Hwang KA,Park JH,Park DS,Kwon O

更新日期：2012-03-30 00:00:00

abstract：Objective:This systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to determine the effect of alpha-lipoic acid (ALA) supplementation on the inflammatory markers among patients with metabolic syndrome (MetS) and related disorders. Methods:We searched the following databases until N...

journal_title：Nutrition & metabolism

authors： Akbari M,Ostadmohammadi V,Tabrizi R,Mobini M,Lankarani KB,Moosazadeh M,Heydari ST,Chamani M,Kolahdooz F,Asemi Z

更新日期：2018-06-05 00:00:00

abstract：: This paper reviews evidence in the context of current research linking dietary fructose to health risk markers.Fructose intake has recently received considerable media attention, most of which has been negative. The assertion has been that dietary fructose is less satiating and more lipogenic than other sugars. Howev...

journal_title：Nutrition & metabolism

authors： Rizkalla SW

更新日期：2010-11-04 00:00:00

abstract：BACKGROUND:Dihydrocapsiate (DCT) is a natural safe food ingredient which is structurally related to capsaicin from chili pepper and is found in the non-pungent pepper strain, CH-19 Sweet. It has been shown to elicit the thermogenic effects of capsaicin but without its gastrointestinal side effects. METHODS:The present...

journal_title：Nutrition & metabolism

authors： Lee TA,Li Z,Zerlin A,Heber D

更新日期：2010-10-06 00:00:00

abstract：Background:Consumption of diet high in soy products is suggested to contribute to lower prostate cancer incidence in Asian men. But little has been known about the influences of dietary patterns on gut microbiota and microbiota-mediated isoflavone metabolism. Here, we determined the influences of western pattern diet o...

journal_title：Nutrition & metabolism

authors： Liu Y,Wu X,Jiang H

更新日期：2019-04-11 00:00:00

abstract：BACKGROUND:Holotranscobalamin, cobalamin-saturated transcobalamin, is the minor fraction of circulating cobalamin (vitamin B12), which is available for cellular uptake and hence is physiologically relevant. Currently, no method allows simple, direct quantification of holotranscobalamin. We now report on the identificat...

journal_title：Nutrition & metabolism

authors： Orning L,Rian A,Campbell A,Brady J,Fedosov SN,Bramlage B,Thompson K,Quadros EV

更新日期：2006-01-04 00:00:00

abstract：BACKGROUND:We previously identified the urinary biomarkers to diagnose calcium deficiency and nutritional rickets by ultra-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry (UPLC/Q-TOF MS/MS). To find biomarkers of calcium deficiency and further confirm these biomarkers in serum, we p...

journal_title：Nutrition & metabolism

authors： Meng F,Fan L,Sun L,Yu Q,Wang M,Sun C

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) is frequently associated with hypovitaminosis D. Vitamin D is endowed with pleiotropic effects, including insulin resistance (IR) and apoptotic pathway. Disruption of the complex mechanism that regulated ovarian apoptosis has been reported in PCOS. Phosphoprotein enriched in ...

journal_title：Nutrition & metabolism

authors： Savastano S,Valentino R,Di Somma C,Orio F,Pivonello C,Passaretti F,Brancato V,Formisano P,Colao A,Beguinot F,Tarantino G

更新日期：2011-11-23 00:00:00

abstract：:[This corrects the article DOI: 10.1186/s12986-016-0154-2.]. ...

journal_title：Nutrition & metabolism

authors： Redondo N,Nova E,Gheorghe A,Díaz LE,Hernández A,Marcos A

更新日期：2017-06-14 00:00:00