Abstract:
BACKGROUND:The objective of this study was to describe the intake of macronutrient, especially fatty acids, and explore their possible effect on diabetic retinopathy (DR) in patients with type 2 diabetes mellitus. METHODS:In this case-control study, we included a total of 146 patients with DR and 148 without DR. The intake of macronutrient was evaluated using a validated food frequency questionnaire. We used logistic regression adjusted for sex, age, diabetes duration, energy intake, educational level, physical activity, waist circumference, systolic blood pressure, high-density lipoprotein cholesterol and diabetes treatment, to estimate odds ratio (ORs) of DR. RESULTS:Patients with DR had significantly lower intake of fibre, monounsaturated fatty acids (MUFA), and palmitic and oleic acid. Inverse associations were observed between MUFA and oleic acid intake in DR. Subjects with intermediate and high MUFA intake were less likely to have DR than those with lower MUFA intake, with ORs of 0.46 (95 % CI: 0.22-0.93) and 0.42 (95 % CI: 0.18-0.97), respectively. Similarly, intermediate and high oleic acid intake were associated with reduced DR frequency compared with low oleic acid intake, with OR values of 0.48 (95 % CI: 0.23-0.97) and 0.37 (95 % CI: 0.16-0.85), respectively. These associations were stronger in patients with a longer diabetes duration. CONCLUSION:In type 2 diabetes mellitus, MUFA and oleic acid intake were inversely associated with DR.
journal_name
Nutr Metab (Lond)journal_title
Nutrition & metabolismauthors
Alcubierre N,Navarrete-Muñoz EM,Rubinat E,Falguera M,Valls J,Traveset A,Vilanova MB,Marsal JR,Hernandez M,Granado-Casas M,Martinez-Gonzalez D,Jurjo C,Franch-Nadal J,Vioque J,Mauricio Ddoi
10.1186/s12986-016-0099-5subject
Has Abstractpub_date
2016-06-04 00:00:00pages
40issn
1743-7075pii
99journal_volume
13pub_type
杂志文章abstract:BACKGROUND:The aim of this study was to evaluate the relationship between intakes of energy-providing macronutrients, and markers of cardio metabolic risk factors in high BMI African American (AA) children. METHODS:A cross sectional analysis of a sample of 9-11 year old children (n = 80) with BMI greater then the 85th...
journal_title:Nutrition & metabolism
pub_type: 杂志文章
doi:10.1186/1743-7075-6-41
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journal_title:Nutrition & metabolism
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doi:10.1186/1743-7075-9-63
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journal_title:Nutrition & metabolism
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abstract:BACKGROUND:The composition of dietary fatty acids (FA) during early life may impact adult adipose tissue (AT) development. We investigated the effects of alpha-linolenic acid (ALA) intake during the suckling/weaning period on AT development and metabolic markers in the guinea pig (GP). METHODS:Newborn GP were fed a 27...
journal_title:Nutrition & metabolism
pub_type: 杂志文章
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更新日期:2010-01-29 00:00:00
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journal_title:Nutrition & metabolism
pub_type: 杂志文章
doi:10.1186/1743-7075-6-24
更新日期:2009-05-29 00:00:00
abstract:Background:It is not clear whether the frequently reported phenomenon of exercise-induced anorexia is exacerbated or blunted in warm or cold environments. Therefore, this study investigated the effects of exercise in three different environmental temperatures vs. rest, on perceptions of appetite, appetite regulating ho...
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更新日期:2019-10-16 00:00:00
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journal_title:Nutrition & metabolism
pub_type: 杂志文章
doi:10.1186/1743-7075-8-8
更新日期:2011-02-02 00:00:00
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更新日期:2020-02-04 00:00:00
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journal_title:Nutrition & metabolism
pub_type: 杂志文章
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更新日期:2007-10-30 00:00:00
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更新日期:2013-06-10 00:00:00
abstract:PURPOSE:To determine the influence of menstrual irregularity, oral contraceptive use and other factors on bone mineral density (BMD) and bone size at different skeletal sites in 135 college-aged fit women. METHODS:Menstrual history, oral contraceptive use, exercise history, and nutritional factors including calcium, c...
journal_title:Nutrition & metabolism
pub_type: 杂志文章
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更新日期:2007-08-06 00:00:00
abstract::We studied the regulation of brain acetyl CoA carboxylase (ACC) activity during food deprivation and under the influence of hormones of glucose homeostasis: glucagon and insulin. Mice were deprived of food and water for time periods of 1, 3, 6, 9, 12 and 24 hours and were then allowed to re-feed for 5, 30 and 60 minut...
journal_title:Nutrition & metabolism
pub_type: 杂志文章
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更新日期:2006-02-16 00:00:00