LXRɑ participates in the mTOR/S6K1/SREBP-1c signaling pathway during sodium palmitate-induced lipogenesis in HepG2 cells.

abstract：BACKGROUND:Recent data suggest that an increased level of high-density lipoprotein cholesterol (HDL-C) is not causally protective against heart disease, shifting focus to other sub-phenotypes of HDL. Prior work on the effects of dietary intakes has focused largely on HDL-C. The goal of this study was to identify the di...

journal_title：Nutrition & metabolism

authors： Kim DS,Burt AA,Ranchalis JE,Jarvik LE,Eintracht JF,Furlong CE,Jarvik GP

更新日期：2014-09-15 00:00:00

abstract：:Glucocorticoids are stress hormones that modulate a large number of physiological actions involved in metabolic, inflammatory, cardiovascular and behavioral processes. The molecular mechanisms and the physiological effects of glucocorticoids have been extensively studied. However, the involvement of glucocorticoid act...

journal_title：Nutrition & metabolism

authors： Wang M

更新日期：2005-02-02 00:00:00

abstract：BACKGROUND:Holotranscobalamin, cobalamin-saturated transcobalamin, is the minor fraction of circulating cobalamin (vitamin B12), which is available for cellular uptake and hence is physiologically relevant. Currently, no method allows simple, direct quantification of holotranscobalamin. We now report on the identificat...

journal_title：Nutrition & metabolism

authors： Orning L,Rian A,Campbell A,Brady J,Fedosov SN,Bramlage B,Thompson K,Quadros EV

更新日期：2006-01-04 00:00:00

abstract：BACKGROUND:Trimethylamine-N-oxide (TMAO) is an independent risk factor for atherosclerosis. Consumption of hawthorn fruit is believed to be cardio-protective, yet whether it is able to suppress the TMAO-induced atherosclerosis remains unexplored. The present study was to investigate the effects of hawthorn fruit extrac...

journal_title：Nutrition & metabolism

authors： He Z,Kwek E,Hao W,Zhu H,Liu J,Ma KY,Chen ZY

更新日期：2021-01-07 00:00:00

abstract：Background:It is not clear whether the frequently reported phenomenon of exercise-induced anorexia is exacerbated or blunted in warm or cold environments. Therefore, this study investigated the effects of exercise in three different environmental temperatures vs. rest, on perceptions of appetite, appetite regulating ho...

journal_title：Nutrition & metabolism

authors： Mandic I,Ahmed M,Rhind S,Goodman L,L'Abbe M,Jacobs I

更新日期：2019-05-06 00:00:00

abstract：Background:Reprogramming of fast-to-slow myofiber switch can improve endurance capacity and alleviate fatigue. Accumulating evidence suggests that a muscle-specific microRNA, miR-499 plays a crucial role in myofiber type transition. In this study, we assessed the effects of natural flavonoid myricetin on exercise endur...

journal_title：Nutrition & metabolism

authors： Wu L,Ran L,Lang H,Zhou M,Yu L,Yi L,Zhu J,Liu L,Mi M

更新日期：2019-05-02 00:00:00

abstract：BACKGROUND:We sought to characterize the effects of dietary macronutrient composition on various hormones implicated in the regulation of insulin sensitivity (IS) and energy expenditure (EE). METHODS:Following 10-15% weight loss, 21 overweight subjects consumed 3 weight-loss maintenance diets [low fat (LF), low glycem...

journal_title：Nutrition & metabolism

authors： Hron BM,Ebbeling CB,Feldman HA,Ludwig DS

更新日期：2017-07-05 00:00:00

abstract：Background:NAFLD as a result of inappropriate diet and obesity, may progress to sever conditions such as: type 2 diabetes mellitus or steatohepatitis, and has recently become a prevalent topic of numerous investigations. Due to its dangerous aftermaths, finding new substances, such as polyphenols and their derivatives,...

journal_title：Nutrition & metabolism

authors： Drygalski K,Berk K,Charytoniuk T,Iłowska N,Łukaszuk B,Chabowski A,Konstantynowicz-Nowicka K

更新日期：2017-11-13 00:00:00

abstract：BACKGROUND:Compared to the corresponding source of inorganic trace minerals (TM), chelated supplements are characterized by better physical heterogeneity and chemical stability and appear to be better absorbed in the gut due to possibly decreased interaction with other feed components. METHODS:This study was designed ...

journal_title：Nutrition & metabolism

authors： Ghasemi HA,Hajkhodadadi I,Hafizi M,Taherpour K,Nazaran MH

更新日期：2020-10-29 00:00:00

abstract：UNLABELLED: BACKGROUND:It is difficult to study the mechanisms of the metabolic syndrome in humans due to the heterogeneous genetic background and lifestyle. The present study investigated changes in the gene and protein profiles in an animal model of the metabolic syndrome to identify the molecular targets associated...

journal_title：Nutrition & metabolism

authors： Chang J,Oikawa S,Ichihara G,Nanpei Y,Hotta Y,Yamada Y,Tada-Oikawa S,Iwahashi H,Kitagawa E,Takeuchi I,Yuda M,Ichihara S

更新日期：2012-09-21 00:00:00

abstract：Background:Consumption of diet high in soy products is suggested to contribute to lower prostate cancer incidence in Asian men. But little has been known about the influences of dietary patterns on gut microbiota and microbiota-mediated isoflavone metabolism. Here, we determined the influences of western pattern diet o...

journal_title：Nutrition & metabolism

authors： Liu Y,Wu X,Jiang H

更新日期：2019-04-11 00:00:00

abstract：BACKGROUND:To study the effects of a pre-germinated brown rice diet (PR) on diabetic neuropathy in streptozotocin (STZ)-induced diabetic rats. METHODS:The effects of a PR diet on diabetic neuropathy in STZ-induced diabetic rats were evaluated and compared with those fed brown rice (BR) or white rice (WR) diets with re...

journal_title：Nutrition & metabolism

authors： Usuki S,Ito Y,Morikawa K,Kise M,Ariga T,Rivner M,Yu RK

更新日期：2007-11-23 00:00:00

abstract：:An association between arteriosclerosis and homocysteine (Hcy) was first demonstrated in 1969. Hcy is a sulfur containing amino acid derived from the essential amino acid methionine (Met). Hyperhomocysteinemia (HHcy) was subsequently shown in several age-related pathologies such as osteoporosis, Alzheimer's disease, P...

journal_title：Nutrition & metabolism

authors： Kumar A,Palfrey HA,Pathak R,Kadowitz PJ,Gettys TW,Murthy SN

更新日期：2017-12-22 00:00:00

abstract：: Paraoxonase 1 (PON1) is a HDL-associated esterase/lactonase and its activity is inversely related to the risk of cardiovascular diseases. The aim of the present study was to evaluate the effect of a high-salt diet on serum PON1 activity in fructose-fed insulin-resistant rats. Adult male Fischer rats were initially di...

journal_title：Nutrition & metabolism

authors： Dornas WC,de Lima WG,Dos Santos RC,de Souza MO,Silva M,Diniz MF,Silva ME

更新日期：2012-06-27 00:00:00

abstract：BACKGROUND:The composition of dietary fatty acids (FA) during early life may impact adult adipose tissue (AT) development. We investigated the effects of alpha-linolenic acid (ALA) intake during the suckling/weaning period on AT development and metabolic markers in the guinea pig (GP). METHODS:Newborn GP were fed a 27...

journal_title：Nutrition & metabolism

authors： Pouteau E,Aprikian O,Grenot C,Reynaud D,Pace-Asciak C,Cuilleron CY,Castañeda-Gutiérrez E,Moulin J,Pescia G,Beysen C,Turner S,Macé K

更新日期：2010-01-29 00:00:00

abstract：: Impaired kidney function and chronic kidney disease (CKD) leading to kidney failure and end-stage renal disease (ESRD) is a serious medical condition associated with increased morbidity, mortality, and in particular cardiovascular disease (CVD) risk. CKD is associated with multiple physiological and metabolic disturb...

journal_title：Nutrition & metabolism

authors： Slee AD

更新日期：2012-04-26 00:00:00

abstract：BACKGROUND:We previously identified the urinary biomarkers to diagnose calcium deficiency and nutritional rickets by ultra-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry (UPLC/Q-TOF MS/MS). To find biomarkers of calcium deficiency and further confirm these biomarkers in serum, we p...

journal_title：Nutrition & metabolism

authors： Meng F,Fan L,Sun L,Yu Q,Wang M,Sun C

更新日期：2020-11-23 00:00:00

abstract：Background:To investigate the association between different obesity phenotypes and the risk of incident hypertension among both genders. Methods:The study population included 3659 Iranians (men = 1540), aged ≥20 years free of hypertension at baseline. Participants were classified into six categories of body mass index...

journal_title：Nutrition & metabolism

authors： Kabootari M,Akbarpour S,Azizi F,Hadaegh F

更新日期：2019-02-27 00:00:00

abstract：BACKGROUND:As an essential trace element selenium plays a significant role in many physiological functions of the organs. It is found within muscles as selenocystein in selenoprotein N, which is involved in redox-modulated calcium homeostasis and in protection against oxidative stress. METHODS:The effects of two diffe...

journal_title：Nutrition & metabolism

authors： Bodnár D,Ruzsnavszky O,Oláh T,Dienes B,Balatoni I,Ungvári É,Benkő I,Babka B,Prokisch J,Csernoch L,Szentesi P

更新日期：2016-11-03 00:00:00

abstract：Background:We previously reported on the anti-obesogenic and anti-inflammatory effects associated with n-3 long-chain polyunsaturated fatty acids (LCPUFA) in our diet-induced obesity (DIO) mouse model. Two isocaloric high-fat diets (HFDs; 48 kJ% fat), HFD (HF) and n-3 LCPUFA-enriched HFD (HF/n-3), and a control diet (C...

journal_title：Nutrition & metabolism

authors： Worsch S,Heikenwalder M,Hauner H,Bader BL

更新日期：2018-09-26 00:00:00

abstract：BACKGROUND:The objective of this study was to describe the intake of macronutrient, especially fatty acids, and explore their possible effect on diabetic retinopathy (DR) in patients with type 2 diabetes mellitus. METHODS:In this case-control study, we included a total of 146 patients with DR and 148 without DR. The i...

journal_title：Nutrition & metabolism

authors： Alcubierre N,Navarrete-Muñoz EM,Rubinat E,Falguera M,Valls J,Traveset A,Vilanova MB,Marsal JR,Hernandez M,Granado-Casas M,Martinez-Gonzalez D,Jurjo C,Franch-Nadal J,Vioque J,Mauricio D

更新日期：2016-06-04 00:00:00

abstract：Objective:This systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to determine the effect of alpha-lipoic acid (ALA) supplementation on the inflammatory markers among patients with metabolic syndrome (MetS) and related disorders. Methods:We searched the following databases until N...

journal_title：Nutrition & metabolism

authors： Akbari M,Ostadmohammadi V,Tabrizi R,Mobini M,Lankarani KB,Moosazadeh M,Heydari ST,Chamani M,Kolahdooz F,Asemi Z

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:α-glucosidase inhibitors regulate postprandial hyperglycemia (PPHG) by impeding the rate of carbohydrate digestion in the small intestine and thereby hampering the diet associated acute glucose excursion. PPHG is a major risk factor for diabetic vascular complications leading to disabilities and mortality in...

journal_title：Nutrition & metabolism

authors： Mohamed Sham Shihabudeen H,Hansi Priscilla D,Thirumurugan K

更新日期：2011-06-29 00:00:00

abstract：: Microsomal triglyceride transfer protein (MTP) was first identified as a major cellular protein capable of transferring neutral lipids between membrane vesicles. Its role as an essential chaperone for the biosynthesis of apolipoprotein B (apoB)-containing triglyceride-rich lipoproteins was established after the reali...

journal_title：Nutrition & metabolism

authors： Hussain MM,Rava P,Walsh M,Rana M,Iqbal J

更新日期：2012-02-21 00:00:00

abstract：BACKGROUND:Reducing dietary energy density has proven to be an effective strategy to reduce energy intakes and promote weight control. This effect appears most robust when a low energy dense preload is consumed before meals. Yet, much discussion continues regarding the optimal form of a preload. The purpose of the pres...

journal_title：Nutrition & metabolism

authors： Silver HJ,Dietrich MS,Niswender KD

更新日期：2011-02-02 00:00:00

abstract：Background:Visceral adipose tissue (VAT) area is a strong predictor of obesity-related cardiometabolic alterations, but its measurement is costly, time consuming and, in some cases, involves radiation exposure. Glutamate, a by-product of branched-chain-amino-acid (BCAA) catabolism, has been shown to be increased in vis...

journal_title：Nutrition & metabolism

authors： Maltais-Payette I,Boulet MM,Prehn C,Adamski J,Tchernof A

更新日期：2018-11-06 00:00:00

abstract：BACKGROUND:Studies have shown that the excessive fructose intake may induce adverse metabolic effects. There is no direct evidence from epidemiological studies to clarify the association between usual amounts of fructose intake and the metabolic syndrome. OBJECTIVE:The aim this study was to determine the association o...

journal_title：Nutrition & metabolism

authors： Hosseini-Esfahani F,Bahadoran Z,Mirmiran P,Hosseinpour-Niazi S,Hosseinpanah F,Azizi F

更新日期：2011-07-12 00:00:00

abstract：BACKGROUND:Two major risk factors for the onset of fatty liver disease are excessive alcohol intake and obesity, the latter being associated with non-alcoholic fatty liver disease (NAFLD). The aim of this study was to examine the effects of black rice extract (BRE) on hepatic steatosis and insulin resistance in high-fa...

journal_title：Nutrition & metabolism

authors： Jang HH,Park MY,Kim HW,Lee YM,Hwang KA,Park JH,Park DS,Kwon O

更新日期：2012-03-30 00:00:00

abstract：:We studied the regulation of brain acetyl CoA carboxylase (ACC) activity during food deprivation and under the influence of hormones of glucose homeostasis: glucagon and insulin. Mice were deprived of food and water for time periods of 1, 3, 6, 9, 12 and 24 hours and were then allowed to re-feed for 5, 30 and 60 minut...

journal_title：Nutrition & metabolism

authors： Karami KJ,Coppola J,Krishnamurthy K,Llanos DJ,Mukherjee A,Venkatachalam KV

更新日期：2006-02-16 00:00:00

abstract：BACKGROUND:Dehydroepiandrosterone (DHEA) is precursor of sex steroid hormone. We demonstrated that acute DHEA injection to type 1 diabetes model rats induced improvement of hyperglycemia. However, the effect of the combination of DHEA administration and exercise training on insulin resistance is still unclear. This stu...

journal_title：Nutrition & metabolism

authors： Sato K,Iemitsu M,Aizawa K,Mesaki N,Ajisaka R,Fujita S

更新日期：2012-05-30 00:00:00