Precipitating factors and targeted therapies in combating the perils of sickle cell disease--- A special nutritional consideration.

abstract：BACKGROUND:Overweight and obesity are widespread chronic disorders defined as excessive fat accumulation, and are major risk factors for several chronic diseases including type 2 diabetes, coronary heart disease, high blood pressure and fatty liver. Changes in lifestyle such as increased physical activity and a healthy...

journal_title：Nutrition & metabolism

authors： Cavalera M,Axling U,Berger K,Holm C

更新日期：2016-12-06 00:00:00

abstract：Background:Obesity has been identified as a major risk factor for a large number of chronic diseases. Understanding factors related to adolescent obesity is critical for prevention of chronic diseases. The associations between sleep duration and obesity among adolescents in the existing literature are controversial. Ou...

journal_title：Nutrition & metabolism

authors： Wang H,Hu R,Du H,Fiona B,Zhong J,Yu M

更新日期：2018-07-09 00:00:00

abstract：Background:The aim of this study was to investigate how the signaling pathway downstream of mTOR/S6K1 contributes to the regulation of SREBP-1c expression during lipogenesis in HepG2 cells. Methods:The model of steatosis was established using human hepatocytes HepG2 and inducting them with sodium palmitate. mTOR, S6K1...

journal_title：Nutrition & metabolism

authors： Zhou Y,Yu S,Cai C,Zhong L,Yu H,Shen W

更新日期：2018-05-02 00:00:00

abstract：: Dietary ratios of omega-3 (n-3) to omega-6 (n-6) polyunsaturated fatty acids (PUFAs) have been implicated in controlling markers of the metabolic syndrome, including insulin sensitivity, inflammation, lipid profiles and adiposity. However, the role of dietary PUFAs in regulating energy systems in healthy relative to ...

journal_title：Nutrition & metabolism

authors： Burghardt PR,Kemmerer ES,Buck BJ,Osetek AJ,Yan C,Koch LG,Britton SL,Evans SJ

更新日期：2010-06-28 00:00:00

abstract：BACKGROUND:The protective effect of HDL is mostly attributed to their metabolic function in reverse cholesterol transport (RCT), a process whereby excess cellular cholesterol is taken up from peripheral cells, processed in HDL particles, and later delivered to the liver for further metabolism and biliary secretion. Mec...

journal_title：Nutrition & metabolism

authors： Lichtenstein L,Serhan N,Annema W,Combes G,Robaye B,Boeynaems JM,Perret B,Tietge UJF,Laffargue M,Martinez LO

更新日期：2013-11-06 00:00:00

abstract：BACKGROUND:The conjugated linoleic acid (CLA) content of beef can be increased by supplementing appropriate beef cattle diets with vegetable oil or oil seed. Yet the effect of consumption of such beef on adipose tissue characteristics is unclear, thus the study was conducted to compare adipose tissue responses of rats ...

journal_title：Nutrition & metabolism

authors： He ML,Mir PS,Okine EK,Napadajlo H

更新日期：2009-04-22 00:00:00

abstract：Background:Elderly people with type 2 diabetes mellitus (T2DM) have an increased risk of diabetes-related microvascular and macrovascular complications, thus diabetic patients with a functioning gastrointestinal tract but without sufficient oral intake require enteral nutrition (EN) formulas to control blood glucose. W...

journal_title：Nutrition & metabolism

authors： Chen CM,Shih CK,Su YJ,Cheang KU,Lo SF,Li SC

更新日期：2019-10-16 00:00:00

abstract：PURPOSE:To determine the influence of menstrual irregularity, oral contraceptive use and other factors on bone mineral density (BMD) and bone size at different skeletal sites in 135 college-aged fit women. METHODS:Menstrual history, oral contraceptive use, exercise history, and nutritional factors including calcium, c...

journal_title：Nutrition & metabolism

authors： Ruffing JA,Nieves JW,Zion M,Tendy S,Garrett P,Lindsay R,Cosman F

更新日期：2007-08-06 00:00:00

abstract：:Nutrition & Metabolism has grown considerably in the ten years since its first article was published. To see how papers published in the journal had an impact we have identified some of the most popular articles in order to measure their influence, observe which fields are important to our readers, and try to explain ...

journal_title：Nutrition & metabolism

authors： Hussain MM,Abel L,Bakillah A

更新日期：2014-03-19 00:00:00

abstract：BACKGROUND:The objective of this study was to describe the intake of macronutrient, especially fatty acids, and explore their possible effect on diabetic retinopathy (DR) in patients with type 2 diabetes mellitus. METHODS:In this case-control study, we included a total of 146 patients with DR and 148 without DR. The i...

journal_title：Nutrition & metabolism

authors： Alcubierre N,Navarrete-Muñoz EM,Rubinat E,Falguera M,Valls J,Traveset A,Vilanova MB,Marsal JR,Hernandez M,Granado-Casas M,Martinez-Gonzalez D,Jurjo C,Franch-Nadal J,Vioque J,Mauricio D

更新日期：2016-06-04 00:00:00

abstract：BACKGROUND:Dietary n-3-polyunsaturated fatty acids (n-3-PUFA) have been shown to reduce body weight and fat mass in rodents as well as in humans in one small short-term study. We conducted this controlled randomized dietary trial to test the hypothesis that n-3-PUFA lower body weight and fat mass by reducing appetite a...

journal_title：Nutrition & metabolism

authors： Kratz M,Callahan HS,Yang PY,Matthys CC,Weigle DS

更新日期：2009-05-29 00:00:00

abstract：BACKGROUND:Compared to the corresponding source of inorganic trace minerals (TM), chelated supplements are characterized by better physical heterogeneity and chemical stability and appear to be better absorbed in the gut due to possibly decreased interaction with other feed components. METHODS:This study was designed ...

journal_title：Nutrition & metabolism

authors： Ghasemi HA,Hajkhodadadi I,Hafizi M,Taherpour K,Nazaran MH

更新日期：2020-10-29 00:00:00

abstract：: Calorie restriction (CR; ~60% of ad libitum, AL intake) has been associated with substantial alterations in body composition and insulin sensitivity. Recently, several proteins that are secreted by nontraditional endocrine tissues, including skeletal muscle and other tissues, have been discovered to modulate energy m...

journal_title：Nutrition & metabolism

authors： Sharma N,Castorena CM,Cartee GD

更新日期：2012-10-15 00:00:00

abstract：BACKGROUND:A number of different pathways to obesity with different metabolic outcomes are recognised. Prenatal undernutrition in rats leads to increased fat deposition in adulthood. However, the form of obesity is metabolically distinct from obesity induced through other pathways (e.g. diet-induced obesity). Previous ...

journal_title：Nutrition & metabolism

authors： Thompson N,Huber K,Bedürftig M,Hansen K,Miles-Chan J,Breier BH

更新日期：2014-10-18 00:00:00

abstract：BACKGROUND:From a health promotion perspective, the use of dietary indices is preferred above single nutrients and foods to evaluate diet quality. Longitudinal research about the association between dietary indices and respectively anthropometric parameters and blood lipids is lacking. The aim of this study was to inve...

journal_title：Nutrition & metabolism

authors： Mertens E,Deforche B,Mullie P,Lefevre J,Charlier R,Knaeps S,Huybrechts I,Clarys P

更新日期：2015-11-19 00:00:00

abstract：BACKGROUND:Resveratrol is a natural polyphenol that has been proposed to improve glycemic control in diabetes, by mechanisms that involve improvement in insulin secretion and activity. In type 1 diabetes (T1D), in which insulin therapy is obligatory, resveratrol treatment has never been investigated. The present study ...

journal_title：Nutrition & metabolism

authors： Yonamine CY,Pinheiro-Machado E,Michalani ML,Freitas HS,Okamoto MM,Corrêa-Giannella ML,Machado UF

更新日期：2016-06-29 00:00:00

abstract：BACKGROUND:A major portion of available fatty acids for adipocyte uptake is derived from lipoprotein lipase (LPL)-mediated hydrolysis of circulating lipoprotein particles. In vivo studies aimed at identifying the precise role of adipocyte-derived LPL in fat storage function of adipose tissue have been unable to provide...

journal_title：Nutrition & metabolism

authors： Gonzales AM,Orlando RA

更新日期：2007-10-30 00:00:00

abstract：BACKGROUND:Cytokines secreted by adipose tissue macrophages (ATMs) significantly alter adipocyte function, inducing inflammatory responses and decreasing insulin sensitivity. However, little relevant information is available regarding the role of microvesicles (MVs) derived from ATMs in macrophage-adipocyte crosstalk. ...

journal_title：Nutrition & metabolism

authors： Zhang Y,Shi L,Mei H,Zhang J,Zhu Y,Han X,Zhu D

更新日期：2015-06-06 00:00:00

abstract：Background:To investigate the association between different obesity phenotypes and the risk of incident hypertension among both genders. Methods:The study population included 3659 Iranians (men = 1540), aged ≥20 years free of hypertension at baseline. Participants were classified into six categories of body mass index...

journal_title：Nutrition & metabolism

authors： Kabootari M,Akbarpour S,Azizi F,Hadaegh F

更新日期：2019-02-27 00:00:00

abstract：BACKGROUND:Total body water (TBW) estimations have been used to estimate body composition, particularly fat-free mass, to aid in nutritional interventions, and to monitor hydration status. In the past, bioimpedance spectroscopy (BIS) devices have been used to estimate TBW. Previous investigations have examined the vali...

journal_title：Nutrition & metabolism

authors： Moon JR,Tobkin SE,Roberts MD,Dalbo VJ,Kerksick CM,Bemben MG,Cramer JT,Stout JR

更新日期：2008-03-19 00:00:00

abstract：BACKGROUND:Although evidence indicates that fatty acids (FA) can affect insulin resistance (IR), not all FA contribute equally to the process. Indeed, monounsaturated FA (MUFA) and polyunsaturated FA (PUFA) are reported to reduce IR, whereas saturated FA (SFA) and trans FA appear to increase IR. However, it is not yet ...

journal_title：Nutrition & metabolism

authors： Ralston JC,Zulyniak MA,Nielsen DE,Clarke S,Badawi A,El-Sohemy A,Ma DW,Mutch DM

更新日期：2013-06-17 00:00:00

abstract：:OBJECTIVE: To compare the effects of isocaloric, energy-restricted very low-carbohydrate ketogenic (VLCK) and low-fat (LF) diets on weight loss, body composition, trunk fat mass, and resting energy expenditure (REE) in overweight/obese men and women. DESIGN: Randomized, balanced, two diet period clinical intervention ...

journal_title：Nutrition & metabolism

authors： Volek J,Sharman M,Gómez A,Judelson D,Rubin M,Watson G,Sokmen B,Silvestre R,French D,Kraemer W

更新日期：2004-11-08 00:00:00

abstract：: Liver steatosis is a frequent histological feature in patients chronically infected with hepatitis C virus (HCV). The relationship between HCV and hepatic steatosis seems to be the result of both epigenetic and genetic factors. In vivo and in vitro studies have shown that HCV can alter intrahepatic lipid metabolism b...

journal_title：Nutrition & metabolism

authors： Mirandola S,Bowman D,Hussain MM,Alberti A

更新日期：2010-02-23 00:00:00

abstract：Background:It is not clear whether the frequently reported phenomenon of exercise-induced anorexia is exacerbated or blunted in warm or cold environments. Therefore, this study investigated the effects of exercise in three different environmental temperatures vs. rest, on perceptions of appetite, appetite regulating ho...

journal_title：Nutrition & metabolism

authors： Mandic I,Ahmed M,Rhind S,Goodman L,L'Abbe M,Jacobs I

更新日期：2019-05-06 00:00:00

abstract：BACKGROUND:Currently, there is a lack of studies examining the effects of adenosine-5'-triphosphate (ATP) supplementation utilizing a long-term, periodized resistance-training program (RT) in resistance-trained populations. Therefore, we investigated the effects of 12 weeks of 400 mg per day of oral ATP on muscular ada...

journal_title：Nutrition & metabolism

authors： Wilson JM,Joy JM,Lowery RP,Roberts MD,Lockwood CM,Manninen AH,Fuller JC,De Souza EO,Baier SM,Wilson SM,Rathmacher JA

更新日期：2013-09-22 00:00:00

abstract：:An association between arteriosclerosis and homocysteine (Hcy) was first demonstrated in 1969. Hcy is a sulfur containing amino acid derived from the essential amino acid methionine (Met). Hyperhomocysteinemia (HHcy) was subsequently shown in several age-related pathologies such as osteoporosis, Alzheimer's disease, P...

journal_title：Nutrition & metabolism

authors： Kumar A,Palfrey HA,Pathak R,Kadowitz PJ,Gettys TW,Murthy SN

更新日期：2017-12-22 00:00:00

abstract：Background:Reprogramming of fast-to-slow myofiber switch can improve endurance capacity and alleviate fatigue. Accumulating evidence suggests that a muscle-specific microRNA, miR-499 plays a crucial role in myofiber type transition. In this study, we assessed the effects of natural flavonoid myricetin on exercise endur...

journal_title：Nutrition & metabolism

authors： Wu L,Ran L,Lang H,Zhou M,Yu L,Yi L,Zhu J,Liu L,Mi M

更新日期：2019-05-02 00:00:00

abstract：BACKGROUND:Diet-induced hepatic steatosis is highly associated with nonalcoholic fatty liver disease, which is related to the development of metabolic syndrome. While advanced stage nonalcoholic hepatic steatosis and steatohepatitis (NASH) result ultimately in fibrosis and cirrhosis, the molecular basis for lipid dropl...

journal_title：Nutrition & metabolism

authors： Shimada Y,Kuninaga S,Ariyoshi M,Zhang B,Shiina Y,Takahashi Y,Umemoto N,Nishimura Y,Enari H,Tanaka T

更新日期：2015-05-20 00:00:00

abstract：Background:Muscle protein synthesis and muscle net balance plateau after moderate protein ingestion in adults. However, it has been suggested that there is no practical limit to the anabolic response of whole-body net balance to dietary protein. Moreover, limited research has addressed the anabolic response to dietary ...

journal_title：Nutrition & metabolism

authors： Mazzulla M,Volterman KA,Packer JE,Wooding DJ,Brooks JC,Kato H,Moore DR

更新日期：2018-09-24 00:00:00

abstract：BACKGROUND:Increasing evidence suggests that diets high in polyunsaturated fatty acids (PUFA) confer health benefits by improving insulin sensitivity and lipid metabolism in liver, muscle and adipose tissue. METHODS:The present study investigates metabolic responses in two different lines of mice either selected for h...

journal_title：Nutrition & metabolism

authors： Nuernberg K,Breier BH,Jayasinghe SN,Bergmann H,Thompson N,Nuernberg G,Dannenberger D,Schneider F,Renne U,Langhammer M,Huber K

更新日期：2011-08-11 00:00:00