Abstract:
BACKGROUND:Errorless learning has advantages over errorful learning. The erroneous items produced during errorful learning compete with correct items at retrieval resulting in decreased memory performance. This interference is associated with an increased demand on executive monitoring processes. Event-related functional magnetic resonance imaging (fMRI) was used to contrast errorless and errorful learning. Learning mode was manipulated by the number of distractors during learning of face-name associations: in errorless learning only the correct name was introduced. During errorful learning either one incorrect name or two incorrect names were additionally introduced in order to modulate the interference in recognition. RESULTS:The behavioural results showed an enhanced memory performance after errorless learning. The veridicality of recognition of the face-name associations was reflected in a left lateralized fronto-temporal-parietal network. The different learning modes were associated with modulations in left prefrontal and parietal regions. CONCLUSIONS:Errorless learning enhances memory performance as compared to errorful learning and underpins the known advantages for errorless learning. During memory retrieval different networks are engaged for specific purposes: Recognition of face-name associations engaged a lateralized fronto-temporal-parietal network and executive monitoring processes of memory engaged the left prefrontal and parietal regions.
journal_name
BMC Neuroscijournal_title
BMC neuroscienceauthors
Hammer A,Tempelmann C,Münte TFdoi
10.1186/1471-2202-14-30subject
Has Abstractpub_date
2013-03-13 00:00:00pages
30issn
1471-2202pii
1471-2202-14-30journal_volume
14pub_type
杂志文章相关文献
BMC NEUROSCIENCE文献大全abstract:BACKGROUND:Trigeminal nerve is a major source of the sensory input of the face, and trigeminal neuropathology models have been reported in rodents with injury to branches of the maxillary or mandibular division of the trigeminal nerve. Non-human primates are neuroanatomically more closely related to human than rodents;...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-13-150
更新日期:2012-12-13 00:00:00
abstract:BACKGROUND:Recent research has revealed that the community of microorganisms inhabiting the gut affects brain development, function and behaviour. In particular, disruption of the gut microbiome during critical developmental windows can have lasting effects on host physiology. Both antibiotic exposure and germ-free con...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/s12868-020-00583-3
更新日期:2020-07-22 00:00:00
abstract:BACKGROUND:The processing of verbal fluency tasks relies on the coordinated activity of a number of brain areas, particularly in the frontal and temporal lobes of the left hemisphere. Recent studies using functional magnetic resonance imaging (fMRI) to study the neural networks subserving verbal fluency functions have ...
journal_title:BMC neuroscience
pub_type: 杂志文章,meta分析
doi:10.1186/1471-2202-15-19
更新日期:2014-01-24 00:00:00
abstract:BACKGROUND:Symptoms of schizophrenia are related to deficits in self-monitoring function, which may be a consequence of irregularity in aspects of the default mode network (DMN). Schizophrenia can also be characterized by a functional abnormality of the brain activity that is reflected in the resting state. Oscillatory...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-15-104
更新日期:2014-09-05 00:00:00
abstract:BACKGROUND:The effects of negative emotion on different processing periods in spatial and verbal working memory (WM) and the possible brain mechanism of the interaction between negative emotion and WM were explored using a high-time resolution event-related potential (ERP) technique and time-locked delayed matching-to-...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-11-60
更新日期:2010-05-07 00:00:00
abstract:BACKGROUND:To date, functional imaging studies of treatment-induced recovery from chronic aphasia only assessed short-term treatment effects after intensive language training. In the present study, we show with functional magnetic resonance imaging (fMRI), that different brain regions may be involved in immediate versu...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-10-118
更新日期:2009-09-22 00:00:00
abstract:BACKGROUND:GABAA receptor-mediated neurotransmission is greatly influenced by cation-chloride cotransporter activity during developmental stages. In embryonic neurons Na-K-2Cl (NKCC1) cotransporters mediate active chloride uptake, thus increasing the intracellular chloride concentration associated with GABA-induced dep...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/s12868-015-0180-4
更新日期:2015-07-14 00:00:00
abstract:BACKGROUND:Gap junction proteins, connexins, are expressed in most endocrine and exocrine glands in the body and are at least in some glands crucial for the hormonal secretion. To what extent connexins are expressed in neurons releasing hormones or neuropeptides from or within the central nervous system is, however, un...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-10-41
更新日期:2009-04-30 00:00:00
abstract:BACKGROUND:Cigarette smoking enhances the risk of stroke. However, the underlying molecular mechanisms are largely unknown. The present study established an in vivo rat secondhand cigarette smoking (SHS) model and examined the hypothesis that SHS upregulates endothelin receptors with increased cerebrovascular contracti...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-12-109
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Several studies have shown that Stroop interference is stronger in children than in adults. However, in a standard Stroop paradigm, stimulus interference and response interference are confounded. The purpose of the present study was to determine whether interference at the stimulus level and the response lev...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-9-82
更新日期:2008-09-05 00:00:00
abstract:BACKGROUND:Functional magnetic resonance imaging (fMRI) in white matter has long been considered controversial. Recently, this viewpoint has been challenged by an emerging body of evidence demonstrating white matter activation in the corpus callosum. The current study aimed to determine whether white matter activation ...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-12-56
更新日期:2011-06-14 00:00:00
abstract:BACKGROUND:A delay in surgical nerve repair results in impaired nerve function in humans, but mechanisms behind the weakened nerve regeneration are not known. Activating transcription factor 3 (ATF3) increases the intrinsic growth state of injured neurons early after injury, but the role of long-term changes and their ...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-9-88
更新日期:2008-09-18 00:00:00
abstract:BACKGROUND:Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a CAG repeat expansion mutation in the coding region of a novel gene. The mechanism of HD is unknown. Most data suggest that polyglutamine-mediated aggregation associated with expression of mutant huntingtin protein (mhtt) contri...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-10-73
更新日期:2009-07-08 00:00:00
abstract:BACKGROUND:Post-stroke hyperglycemia appears to be associated with poor outcome from stroke, greater mortality, and reduced functional recovery. Focal cerebral ischemia data support that neural stem cells (NSCs) play an important role in post-ischemic repair. Here we sought to evaluate the negative effects of hyperglyc...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-14-24
更新日期:2013-03-04 00:00:00
abstract:BACKGROUND:Astrocytes are responsible for a broad range of functions that maintain homeostasis in the brain. However, their response to the pro-inflammatory cytokines released by activated microglia in various neurological pathologies may exacerbate neurodegenerative processes. Accumulating evidence suggests that omega...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/s12868-021-00611-w
更新日期:2021-01-27 00:00:00
abstract:BACKGROUND:Growing evidence shows that, in vivo, the precursor of Nerve Growth Factor (NGF), proNGF, displays biological activities different from those of its mature NGF counterpart, mediated by distinct, and somewhat complementary, receptor binding properties. NGF and proNGF induce distinct transcriptional signatures...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-15-48
更新日期:2014-04-08 00:00:00
abstract:BACKGROUND:Circadian clocks are endogenous biochemical oscillators that control daily behavioral rhythms in all living organisms. In fruit fly, the circadian rhythms are typically studied using power spectra of multiday behavioral recordings. Despite decades of study, a quantitative understanding of the temporal shape ...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/s12868-016-0248-9
更新日期:2016-04-18 00:00:00
abstract:BACKGROUND:Myzus persicae is a globally important aphid pest with a history of developing resistance to insecticides. Unusually, neonicotinoids have remained highly effective as control agents despite nearly two decades of steadily increasing use. In this study, a clone of M. persicae collected from southern France was...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-12-51
更新日期:2011-05-31 00:00:00
abstract:BACKGROUND:Odorant stimuli can access the olfactory epithelium either orthonasally, by inhalation through the external nares, or retronasally by reverse airflow from the oral cavity. There is evidence that odors perceived through these two routes can differ in quality and intensity. We were curious whether such differe...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-14-45
更新日期:2013-04-08 00:00:00
abstract:BACKGROUND:Oxidative stress has shown to contribute in the mechanisms underlying apoptotic cell death occurring in AIDS-dementia complex. Here we investigated the role of peroxynitrite in apoptosis occurring in astroglial cells incubated with supernatants of HIV-infected human primary macrophages (M/M). RESULTS:Flow c...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-3-13
更新日期:2002-09-16 00:00:00
abstract:BACKGROUND:The zitter (zi/zi) rat, a loss-of-function mutant of the glycosylated transmembrane protein attractin (atrn), exhibits widespread age-dependent spongiform degeneration, hypomyelination, and abnormal metabolism of reactive oxygen species (ROS) in the brain. To date, the mechanisms underlying these phenotypes ...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-9-35
更新日期:2008-04-05 00:00:00
abstract:BACKGROUND:Recovery following stroke depends on cellular plasticity in the perilesional zone (PZ). Doublecortin (DCX), a protein mainly labeling immature neurons in neurogenic niches is also highly expressed in the vicinity of focal cortical infarcts. Notably, the number of DCX+ cells positively correlates with the rec...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/s12868-015-0160-8
更新日期:2015-04-15 00:00:00
abstract:BACKGROUND:Efficient multisensory integration is of vital importance for adequate interaction with the environment. In addition to basic binding cues like temporal and spatial coherence, meaningful multisensory information is also bound together by content-based associations. Many functional Magnetic Resonance Imaging ...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-11-11
更新日期:2010-02-02 00:00:00
abstract:BACKGROUND:Precise control of developmental and cell-specific expression of the brain-derived neurotrophic factor (BDNF) gene is essential for normal neuronal development and the diverse functions of BDNF in the adult organism. We previously showed that the zebrafish BDNF gene has multiple promoters. The complexity of ...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-5-19
更新日期:2004-05-21 00:00:00
abstract:BACKGROUND:Multi-sensory integration is necessary for organisms to discriminate different environmental stimuli and thus determine behavior. Caenorhabditis elegans has 12 pairs of amphid sensory neurons, which are involved in generating behaviors such as thermotaxis toward cultivation temperature, and chemotaxis toward...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-9-106
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:One of the most promising options for treatment of stroke using adult stem cells are human umbilical cord blood (HUCB) cells that were already approved for therapeutic efficacy in vivo. However, complexity of animal models has thus far limited the understanding of beneficial cellular mechanisms. To address t...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-9-30
更新日期:2008-02-29 00:00:00
abstract:BACKGROUND:The neurological complications of HIV infection remain poorly understood. Clinically, in vivo 1H magnetic resonance spectroscopy (MRS) demonstrates brain injury caused by HIV infection even when the MRI is normal. Our goal was to undertsand the dynamics of cerebral injury by performing a longitudinal in vivo...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-5-10
更新日期:2004-03-05 00:00:00
abstract:BACKGROUND:Previous studies showed that anodal transcranial DC stimulation (tDCS) applied to the primary motor cortex of the affected hemisphere (M1affected hemisphere) after subcortical stroke transiently improves performance of complex tasks that mimic activities of daily living (ADL). It is not known if relatively s...
journal_title:BMC neuroscience
pub_type: 临床试验,杂志文章
doi:10.1186/1471-2202-7-73
更新日期:2006-11-03 00:00:00
abstract:BACKGROUND:Acute subdural hemorrhage (ASDH) is a severe consequence of traumatic brain injury. The occurrence of subdural blood increases the lethality of these patients independent of the amount of blood or elevated intracranial pressure. Thrombin is one of the potential harmful blood components. Possible harmful effe...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/s12868-018-0481-5
更新日期:2018-12-27 00:00:00
abstract:BACKGROUND:Adult neurogenesis continuously adds new neurons to the dentate gyrus and the olfactory bulb. It involves the proliferation and subsequent differentiation of neuronal progenitors, and is thus closely linked to the cell cycle machinery. Cell cycle progression is governed by the successive expression, activati...
journal_title:BMC neuroscience
pub_type: 杂志文章
doi:10.1186/1471-2202-13-46
更新日期:2012-05-07 00:00:00