Specific antioxidant properties of human serum albumin.

abstract：BACKGROUND:Infection and sepsis are a main cause of acute-on-chronic liver failure (ACLF). Adequate dosing of antimicrobial therapy is of central importance to improve outcome. Liver failure may alter antibiotic drug concentrations via changes of drug distribution and elimination. We studied the pharmacokinetics of mer...

journal_title：Annals of intensive care

authors： Grensemann J,Busse D,König C,Roedl K,Jäger W,Jarczak D,Iwersen-Bergmann S,Manthey C,Kluge S,Kloft C,Fuhrmann V

更新日期：2020-04-22 00:00:00

abstract：INTRODUCTION:Capillary leak in critically ill patients leads to interstitial edema. Fluid overload is independently associated with poor prognosis. Bedside measurement of intra-abdominal pressure (IAP), extravascular lung water index (EVLWI), fluid balance, and capillary leak index (CLI) may provide a valuable prognost...

journal_title：Annals of intensive care

authors： Cordemans C,De Laet I,Van Regenmortel N,Schoonheydt K,Dits H,Huber W,Malbrain ML

更新日期：2012-07-05 00:00:00

abstract：BACKGROUND:Continuous glucose monitoring (CGM) has not yet been implemented in the intensive care unit (ICU) setting. The purpose of this study was to evaluate reliability, feasibility, nurse acceptance and accuracy of the Medtronic Sentrino(®) CGM system in critically ill patients. METHODS:Sensors were inserted into ...

journal_title：Annals of intensive care

authors： Wollersheim T,Engelhardt LJ,Pachulla J,Moergeli R,Koch S,Spies C,Hiesmayr M,Weber-Carstens S

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Acute respiratory distress syndrome (ARDS) patients may present impaired in lung function and structure after hospital discharge that may be related to mechanical ventilation strategy. The aim of this study was to evaluate the association between functional and structural lung impairment, N-terminal-peptide ...

journal_title：Annals of intensive care

authors： Toufen Junior C,De Santis Santiago RR,Hirota AS,Carvalho ARS,Gomes S,Amato MBP,Carvalho CRR

更新日期：2018-12-07 00:00:00

abstract：BACKGROUND:Antibiotics are frequently used in intensive care units (ICUs), and their use is associated with the emergence of bacterial resistance to antibiotics. The aim of this study was to investigate the association between the emergence of Pseudomonas aeruginosa resistance and the duration of antibiotic exposure or...

journal_title：Annals of intensive care

authors： Yusuf E,Van Herendael B,Verbrugghe W,Ieven M,Goovaerts E,Bergs K,Wouters K,Jorens PG,Goossens H

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The consequences of the ageing population concerning ICU hospitalisation need to be adequately described. We believe that this discussion should be disease specific. A focus on respiratory infections is of particular interest, because it is strongly associated with old age. Our objective was to assess trends...

journal_title：Annals of intensive care

authors： Laporte L,Hermetet C,Jouan Y,Gaborit C,Rouve E,Shea KM,Si-Tahar M,Dequin PF,Grammatico-Guillon L,Guillon A

更新日期：2018-08-15 00:00:00

abstract：BACKGROUND:The impact on infectious risk of ultrasound guidance at insertion remains controversial in short-term arterial catheters (ACs). The present study investigated the association between ultrasound guidance (US) during AC insertion and major catheter-related infections (MCRI), catheter-related bloodstream infect...

journal_title：Annals of intensive care

authors： Buetti N,Ruckly S,Lucet JC,Bouadma L,Schwebel C,Mimoz O,Timsit JF

更新日期：2020-07-08 00:00:00

abstract：BACKGROUND:Hyponatremia occurring as a result of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) or cerebral salt wasting syndrome is a common complication in patients with subarachnoid hemorrhage (SAH). The efficacy and safety of urea as treatment for SIADH-induced hyponatremia has not been report...

journal_title：Annals of intensive care

authors： Pierrakos C,Taccone FS,Decaux G,Vincent JL,Brimioulle S

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Healthcare-associated bloodstream infections are related to both increased antibiotic use and risk of adverse outcomes. An in-depth understanding of their epidemiology is essential to reduce occurrence and to improve outcomes by targeted prevention strategies. The objectives of the study were to determine th...

journal_title：Annals of intensive care

authors： Culshaw N,Glover G,Whiteley C,Rowland K,Wyncoll D,Jones A,Shankar-Hari M

更新日期：2014-11-25 00:00:00

abstract：BACKGROUND:Despite advances in the management of bloodstream infections (BSI) caused by Candida spp., the mortality still remains high in critically ill patients. The worldwide epidemiology of yeast-related BSI is subject to changing species distribution and resistance patterns, challenging antifungal treatment strateg...

journal_title：Annals of intensive care

authors： Schroeder M,Weber T,Denker T,Winterland S,Wichmann D,Rohde H,Ozga AK,Fischer M,Kluge S

更新日期：2020-10-16 00:00:00

abstract：: Thrombocytopenia is a very frequent disorder in the intensive care unit. Many etiologies should be searched, and therapeutic approaches differ according to these different causes. However, no guideline exists regarding optimum practices for these situations in critically ill patients. We present recommendations for t...

journal_title：Annals of intensive care

authors： Van der Linden T,Souweine B,Dupic L,Soufir L,Meyer P

更新日期：2012-08-28 00:00:00

abstract：BACKGROUND:To assess the impact of a real-time random safety tool on structure, process and outcome indicators. METHODS:Prospective study conducted over a period of 12 months in two adult patient intensive care units. Safety rounds were conducted three days a week ascertaining 37 safety measures (grouped into 10 block...

journal_title：Annals of intensive care

authors： Bodí M,Oliva I,Martín MC,Gilavert MC,Muñoz C,Olona M,Sirgo G

更新日期：2017-12-01 00:00:00

abstract：:The 2018 Paris Intensive Care symposium entitled "Update in Neurocritical Care" was organized in Paris, June 21-22, 2018, under the auspices of the French Intensive Care Society. This 2-day post-graduate educational symposium comprised several chapters, aiming first to provide all-board intensivists with current stand...

journal_title：Annals of intensive care

authors： Oddo M,Bracard S,Cariou A,Chanques G,Citerio G,Clerckx B,Godeau B,Godier A,Horn J,Jaber S,Jung B,Kuteifan K,Leone M,Mailles A,Mazighi M,Mégarbane B,Outin H,Puybasset L,Sharshar T,Sandroni C,Sonneville R,Weiss N

更新日期：2019-04-16 00:00:00

abstract：BACKGROUND:Among intensive care unit (ICU) patients with acute respiratory distress syndrome (ARDS), apart from acute cor pulmonale (ACP), the frequency and prognostic impact of basic critical care echocardiography (BCCE) abnormalities are not well defined. METHODS:Observational study of patients with ARDS, admitted f...

journal_title：Annals of intensive care

authors： See KC,Ng J,Siow WT,Ong V,Phua J

更新日期：2017-12-19 00:00:00

abstract：BACKGROUND:As the population ages and cancer therapies improve, there is an increased call for elderly cancer patients to be admitted to the intensive care unit (ICU). This study aimed to assess short-term survival and prognostic factors in critically ill patients with solid tumors aged ≥65 years. METHODS:We conducted...

journal_title：Annals of intensive care

authors： Auclin E,Charles-Nelson A,Abbar B,Guérot E,Oudard S,Hauw-Berlemont C,Thibault C,Monnier A,Diehl JL,Katsahian S,Fagon JY,Taieb J,Aissaoui N

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Critical illness has detrimental effects on the diaphragm, but the impact of critical illness on other major muscles of the respiratory pump has been largely neglected. This study aimed to determine the impact of critical illness on the most important muscles of the respiratory muscle pump, especially on the...

journal_title：Annals of intensive care

authors： IJland MM,Lemson J,van der Hoeven JG,Heunks LMA

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown. The aim of our study was to evaluate the effect of an intraoperative goal-directed fluid restriction (GDFR) strategy on the postoperative outcome of high-risk patients undergoing brain sur...

journal_title：Annals of intensive care

authors： Luo J,Xue J,Liu J,Liu B,Liu L,Chen G

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:In randomised controlled trials, procalcitonin (PCT)-guided antibiotic treatment has been proven to significantly reduce length of antibiotic therapy in intensive care unit (ICU) patients. However, concern was raised on low protocol adherence and high rates of overruling, and thus the value of PCT-guided tre...

journal_title：Annals of intensive care

authors： Hohn A,Balfer N,Heising B,Hertel S,Wiemer JC,Hochreiter M,Schröder S

更新日期：2018-06-04 00:00:00

abstract：:In the past, the only treatment of acute exacerbations of obstructive diseases with hypercapnic respiratory failure refractory to medical treatment was invasive mechanical ventilation (IMV). Considerable technical improvements transformed extracorporeal techniques for carbon dioxide removal in an attractive option to ...

journal_title：Annals of intensive care

authors： Morales-Quinteros L,Del Sorbo L,Artigas A

更新日期：2019-07-02 00:00:00

abstract：: Multiple experimental and human trials have shown that microcirculatory alterations are frequent in sepsis. In this review, we discuss the characteristics of these alterations, the various mechanisms potentially involved, and the implications for therapy. Sepsis-induced microvascular alterations are characterized by ...

journal_title：Annals of intensive care

authors： De Backer D,Donadello K,Taccone FS,Ospina-Tascon G,Salgado D,Vincent JL

更新日期：2011-07-19 00:00:00

abstract：:The death of a loved one is often an ordeal and a tragedy for those who witness it, as death is not merely the end of a life, but also the end of an existence, the loss of a unique individual who is special and irreplaceable. In some situations, end-of-life signs, such as agonal gasps, can be an almost unbearable "sig...

journal_title：Annals of intensive care

authors： Daubin C,Haddad L,Folscheid D,Boyer A,Chalumeau-Lemoine L,Guisset O,Hubert P,Pillot J,Robert R,Dreyfuss D

更新日期：2014-07-08 00:00:00

abstract：BACKGROUND:Empirical antimicrobial therapy (EAT) is a challenge for community-acquired, hospital-acquired and ventilator-associated pneumonia, particularly in the context of the increasing occurrence of third-generation cephalosporin-resistant Enterobacterales (3GCR-E), including extended-spectrum beta-lactamase Entero...

journal_title：Annals of intensive care

authors： Elsa M,Matthieu LD,De Ponfilly Gauthier P,Hanaa B,Rishma A,Emmanuelle C,Benjamin S,Glenn CB,Hervé J

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:Delayed intubation is associated with high mortality. There is a lack of objective criteria to decide the time of intubation. We assessed a recently described combined oxygenation index (ROX index) to predict intubation in immunocompromised patients. The study is a secondary analysis of randomized trials in ...

journal_title：Annals of intensive care

authors： Lemiale V,Dumas G,Demoule A,Pène F,Kouatchet A,Bisbal M,Nseir S,Argaud L,Kontar L,Klouche K,Barbier F,Seguin A,Louis G,Constantin JM,Mayaux J,Wallet F,Peigne V,Girault C,Oziel J,Nyunga M,Terzi N,Bouadma L,Laut

更新日期：2021-01-27 00:00:00

abstract：: Cancer is a leading cause of death in children. In the past decades, there has been a marked increase in overall survival of children with cancer. However, children whose treatment includes hematopoietic stem cell transplantation still represent a subpopulation with a higher risk of mortality. These improvements in m...

journal_title：Annals of intensive care

authors： Demaret P,Pettersen G,Hubert P,Teira P,Emeriaud G

更新日期：2012-06-12 00:00:00

abstract：BACKGROUND:The use of novel sepsis biomarkers has increased in recent years. However, their prognostic value with respect to illness severity has not been explored. In this work, we examined the ability of mid-regional proadrenomedullin (MR-proADM) in predicting mortality in sepsis patients with different degrees of or...

journal_title：Annals of intensive care

authors： Andaluz-Ojeda D,Nguyen HB,Meunier-Beillard N,Cicuéndez R,Quenot JP,Calvo D,Dargent A,Zarca E,Andrés C,Nogales L,Eiros JM,Tamayo E,Gandía F,Bermejo-Martín JF,Charles PE

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) occurs in up to 50% of all critically ill patients and hemodynamic abnormalities are assumed to contribute, but their nature and share is still unclear. We explored the associations between hemodynamic variables, including cardiac index and right ventricular function, and the occurr...

journal_title：Annals of intensive care

authors： Wiersema R,Koeze J,Hiemstra B,Pettilä V,Perner A,Keus F,van der Horst ICC,SICS Study Group.

更新日期：2019-03-13 00:00:00

abstract：: Red blood cells (RBC) storage facilitates the supply of RBC to meet the clinical demand for transfusion and to avoid wastage. However, RBC storage is associated with adverse changes in erythrocytes and their preservation medium. These changes are responsible for functional alterations and for the accumulation of pote...

journal_title：Annals of intensive care

authors： Aubron C,Nichol A,Cooper DJ,Bellomo R

更新日期：2013-01-15 00:00:00

abstract：:Although chest X-ray remains a fundamental lung imaging technique, through the years, CT scan has significantly improved our knowledge of the pathophysiological process and currently is the reference lung imaging tool for both a visual and quantitative computer-based analysis. The application of lung CT in the early p...

journal_title：Annals of intensive care

authors： Chiumello D,Formenti P,Coppola S

更新日期：2019-01-22 00:00:00

abstract：:The bedside hemodynamic assessment of the critically ill remains challenging since blood volume, arterial-venous interaction and compliance are not measured directly. Mean circulatory filling pressure (Pmcf) is the blood pressure throughout the vascular system at zero flow. Animal studies have shown Pmcf provides info...

journal_title：Annals of intensive care

authors： Wijnberge M,Sindhunata DP,Pinsky MR,Vlaar AP,Ouweneel E,Jansen JR,Veelo DP,Geerts BF

更新日期：2018-06-20 00:00:00

abstract：UNLABELLED: BACKGROUND:A history of prolonged and excessive consumption of alcohol increases the risk for infections. The goal of this study was to investigate circulating white blood cells (WBC) differentiated by flow cytometry and neutrophil CD64 expression in excessive alcohol drinkers versus abstinent or moderate ...

journal_title：Annals of intensive care

authors： Gacouin A,Roussel M,Gros A,Sauvadet E,Uhel F,Chimot L,Marque S,Camus C,Fest T,Le Tulzo Y

更新日期：2012-12-31 00:00:00