Abstract：
:Although chest X-ray remains a fundamental lung imaging technique, through the years, CT scan has significantly improved our knowledge of the pathophysiological process and currently is the reference lung imaging tool for both a visual and quantitative computer-based analysis. The application of lung CT in the early phase of ARDS has led to changes in the clinical management in up of thirty percent of the patients. Although CT requires the transportation of the patient to the radiological department and exposes the patient to high dose of radiation, given the several information that CT can offer, it should be applied at least one time, in the early phase in all ARDS patients. CT plays an irreplaceable role to describe and assess the lung recruitability and to help a more physiological setting of mechanical ventilation.
journal_name
Ann Intensive Carejournal_title
Annals of intensive careauthors
Chiumello D,Formenti P,Coppola Sdoi
10.1186/s13613-019-0497-8subject
Has Abstractpub_date
2019-01-22 00:00:00pages
12issue
1issn
2110-5820pii
10.1186/s13613-019-0497-8journal_volume
9pub_type
社论abstract：BACKGROUND:Hyperglycaemia is commonplace in the adult intensive care unit (ICU), associated with increased morbidity and mortality. Effective glycaemic control (GC) can reduce morbidity and mortality, but has proven difficult. STAR is a proven, effective model-based ICU GC protocol that uniquely maintains normo-glycaem...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-017-0351-9
更新日期：2018-01-10 00:00:00
abstract：BACKGROUND:Lactate is a robust prognostic marker for the outcome of critically ill patients. Several small studies reported that metformin users have higher lactate levels at ICU admission without a concomitant increase in mortality. However, this has not been investigated in a larger cohort. We aimed to determine whet...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-020-00652-0
更新日期：2020-03-26 00:00:00
abstract：BACKGROUND:Optimal anti-bacterial activity of meropenem requires maintenance of its plasma concentration (Cp) above the minimum inhibitory concentration (MIC) of the pathogen for at least 40% of the dosing interval (fT > MIC > 40). We aimed to determine whether a 3-h extended infusion (EI) of meropenem achieves fT > MI...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-019-0622-8
更新日期：2020-01-10 00:00:00
abstract：:Animal experiments are widely used in preclinical medical research with the goal of disease modeling and exploration of novel therapeutic approaches. In the context of sepsis and septic shock, the translation into clinical practice has been disappointing. Classical animal models of septic shock usually involve one-sex...
journal_title：Annals of intensive care
pub_type： 杂志文章,评审
doi：10.1186/s13613-019-0543-6
更新日期：2019-06-10 00:00:00
abstract：BACKGROUND:Empirical antimicrobial therapy (EAT) is a challenge for community-acquired, hospital-acquired and ventilator-associated pneumonia, particularly in the context of the increasing occurrence of third-generation cephalosporin-resistant Enterobacterales (3GCR-E), including extended-spectrum beta-lactamase Entero...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-020-00754-9
更新日期：2020-10-29 00:00:00
abstract：BACKGROUND:As the population ages and cancer therapies improve, there is an increased call for elderly cancer patients to be admitted to the intensive care unit (ICU). This study aimed to assess short-term survival and prognostic factors in critically ill patients with solid tumors aged ≥65 years. METHODS:We conducted...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-017-0250-0
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:To assess the impact of a real-time random safety tool on structure, process and outcome indicators. METHODS:Prospective study conducted over a period of 12 months in two adult patient intensive care units. Safety rounds were conducted three days a week ascertaining 37 safety measures (grouped into 10 block...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-017-0245-x
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Acute lung injury and the acute respiratory distress syndrome (ALI/ARDS) are characterized by pulmonary oedema, measured as extravascular lung water (EVLW). The chest radiograph (CXR) can potentially estimate the quantity of lung oedema while the transpulmonary thermodilution method measures the amount of EV...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/2110-5820-3-25
更新日期：2013-08-11 00:00:00
abstract：BACKGROUND:Delayed intubation is associated with high mortality. There is a lack of objective criteria to decide the time of intubation. We assessed a recently described combined oxygenation index (ROX index) to predict intubation in immunocompromised patients. The study is a secondary analysis of randomized trials in ...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-021-00801-z
更新日期：2021-01-27 00:00:00
abstract：: Red blood cells (RBC) storage facilitates the supply of RBC to meet the clinical demand for transfusion and to avoid wastage. However, RBC storage is associated with adverse changes in erythrocytes and their preservation medium. These changes are responsible for functional alterations and for the accumulation of pote...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/2110-5820-3-2
更新日期：2013-01-15 00:00:00
abstract：BACKGROUND:The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown. The aim of our study was to evaluate the effect of an intraoperative goal-directed fluid restriction (GDFR) strategy on the postoperative outcome of high-risk patients undergoing brain sur...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-017-0239-8
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Acute respiratory distress syndrome (ARDS) patients may present impaired in lung function and structure after hospital discharge that may be related to mechanical ventilation strategy. The aim of this study was to evaluate the association between functional and structural lung impairment, N-terminal-peptide ...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-018-0469-4
更新日期：2018-12-07 00:00:00
abstract：BACKGROUND:Continuous glucose monitoring (CGM) has not yet been implemented in the intensive care unit (ICU) setting. The purpose of this study was to evaluate reliability, feasibility, nurse acceptance and accuracy of the Medtronic Sentrino(®) CGM system in critically ill patients. METHODS:Sensors were inserted into ...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-016-0167-z
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:SARS coronavirus 2 (SARS-CoV-2) is responsible for high morbidity and mortality worldwide, mostly due to the exacerbated inflammatory response observed in critically ill patients. However, little is known about the kinetics of the systemic immune response and its association with survival in SARS-CoV-2+ pati...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-020-00798-x
更新日期：2021-01-13 00:00:00
abstract：BACKGROUND:Intensivists' clinical decision making pursues two main goals for patients: to decrease mortality and to improve quality of life and functional status in survivors. Patient-important outcomes are gaining wide acceptance in most fields of clinical research. We sought to systematically review how well patient-...
journal_title：Annals of intensive care
pub_type： 杂志文章,评审
doi：10.1186/s13613-017-0243-z
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Hypoxic hepatitis (HH) is a type of acute hepatic injury that is histologically characterized by centrilobular liver cell necrosis and that is caused by insufficient oxygen delivery to the hepatocytes. Typical for HH is the sudden and significant increase of aspartate aminotransferase (AST) in response to ca...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-018-0356-z
更新日期：2018-01-30 00:00:00
abstract：BACKGROUND:The use of novel sepsis biomarkers has increased in recent years. However, their prognostic value with respect to illness severity has not been explored. In this work, we examined the ability of mid-regional proadrenomedullin (MR-proADM) in predicting mortality in sepsis patients with different degrees of or...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-017-0238-9
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Aneurysmal subarachnoid hemorrhage (SAH) is a serious condition associated with high mortality rates and long-term disability. We investigated the impact of fluid balance on neurologic outcome after adjustment for possible confounders related to intensive care therapy and extra-cerebral organ failure during ...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-016-0128-6
更新日期：2016-12-01 00:00:00
abstract：:Although improving, the mortality from septic shock still remains high despite increased international awareness. As a consequence, much effort has focused on alternative treatment strategies in an effort to improve outcomes. The application of blood purification therapies to improve immune homeostasis has been sugges...
journal_title：Annals of intensive care
pub_type： 杂志文章,评审
doi：10.1186/s13613-019-0530-y
更新日期：2019-05-14 00:00:00
abstract：BACKGROUND:The impact of neutropenia in critically ill immunocompromised patients admitted in a context of acute respiratory failure (ARF) remains uncertain. The primary objective was to assess the prognostic impact of neutropenia on outcomes of these patients. Secondary objective was to assess etiology of ARF accordin...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-020-00764-7
更新日期：2020-10-22 00:00:00
abstract：BACKGROUND:Despite improvements in intermittent hemodialysis management, intradialytic hemodynamic instability (IHI) remains a common issue that could account for increased mortality and delayed renal recovery. However, predictive factors of IHI remain poorly explored. The objective of this study was to evaluate the re...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-020-00663-x
更新日期：2020-04-22 00:00:00
abstract：:This review examines the available evidence for targeting a specific mean arterial pressure (MAP) in sepsis resuscitation. The clinical data suggest that targeting an MAP of 65-70 mmHg in patients with septic shock who do not have chronic hypertension is a reasonable first approximation. Whereas in patients with chron...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-015-0085-5
更新日期：2015-12-01 00:00:00
abstract：:The majority of resuscitated patients present with underlying cardiac disease, and out of these myocardial infarction is most common. Immediate interventional treatment is recommended and routinely requires dual antiplatelet therapy including aspirin and a P2Y12-inhibitor. Therapeutic hypothermia or target temperature...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-018-0366-x
更新日期：2018-02-21 00:00:00
abstract：BACKGROUND:Healthcare-associated bloodstream infections are related to both increased antibiotic use and risk of adverse outcomes. An in-depth understanding of their epidemiology is essential to reduce occurrence and to improve outcomes by targeted prevention strategies. The objectives of the study were to determine th...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-014-0034-8
更新日期：2014-11-25 00:00:00
abstract：BACKGROUND:Despite advances in the management of bloodstream infections (BSI) caused by Candida spp., the mortality still remains high in critically ill patients. The worldwide epidemiology of yeast-related BSI is subject to changing species distribution and resistance patterns, challenging antifungal treatment strateg...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-020-00755-8
更新日期：2020-10-16 00:00:00
abstract：BACKGROUND:Mortality of critically ill hematology (HM) patients has improved over time. Thus, those patients require an extensive diagnostic workup and the optimal use of available treatments. There are no data regarding nutrition strategy for critically ill HM patients, while nutritional support is crucial for both HM...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-019-0527-6
更新日期：2019-05-07 00:00:00
abstract：BACKGROUND:High-frequency oscillatory ventilation (HFOV) is a common but unproven management strategy in paediatric critical care. Oscillator settings have been traditionally guided by patient age and/or weight rather than by lung mechanics, thereby potentially negating any beneficial effects. We have adopted an open-l...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-019-0492-0
更新日期：2019-01-18 00:00:00
abstract：BACKGROUND:The initial management of a trauma patient is a critical and demanding period. The use of extended focused assessment sonography for trauma (eFAST) has become more prevalent in trauma rooms, raising questions about the real "added value" of chest X-rays (CXRs) and pelvic X-rays (PXR), particularly in haemody...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-016-0166-0
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Pre-evaluation of endogenous immunoglobulin levels is a potential strategy to improve the results of intravenous immunoglobulins in sepsis, but more work has to be done to identify those patients who could benefit the most from this treatment. The objective of this study was to evaluate the impact of endogen...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-017-0268-3
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVES:To assess outcomes at hospital discharge and day-120 after intensive care unit (ICU) discharge among patients with solid cancer admitted to ICU and to identify characteristics associated with in-hospital and day-120 after ICU discharge mortalities. DESIGN:International, multicenter, retrospective study. SE...
journal_title：Annals of intensive care
pub_type： 杂志文章
doi：10.1186/s13613-018-0386-6
更新日期：2018-03-27 00:00:00
