Ultrasound guidance and risk for intravascular catheter-related infections among peripheral arterial catheters: a post-hoc analysis of two large randomized-controlled trials.

Abstract:

BACKGROUND:The impact on infectious risk of ultrasound guidance at insertion remains controversial in short-term arterial catheters (ACs). The present study investigated the association between ultrasound guidance (US) during AC insertion and major catheter-related infections (MCRI), catheter-related bloodstream infections (CR-BSI) or colonization, using univariate and multivariate marginal Cox model for clustered data. The skin colonization at catheter removal was evaluated to explain our results. RESULTS:We used individual data from two multicenter randomized-controlled trials (RCTs) that included a total of 3029 patients, 10 ICUs and 3950 ACs. US guidance was used for 386 (9.8%) catheter placements. In the univariate Cox model analysis, AC insertion with US versus without US exhibited similar risks for MCRI (HR 0.86, CI 95% 0.27-2.72, p = 0.79), CR-BSI (HR 0.87, CI 95% 0.20-3.72, p = 0.85) and catheter colonization (HR 1.31, CI 95% 0.92-1.86, p = 0.13). After adjustment on confounders, risks associated with US guidance remained similar versus non-US for MCRI (HR 0.71, CI 95% 0.23-2.24, p = 0.56), CR-BSI (HR 0.71, CI 95% 0.17-3.00, p = 0.63) and catheter colonization (HR 0.92, CI 95% 0.63-1.34, p = 0.67). No differences between US and non-US for MCRI, CR-BSI and colonization were observed according to the insertion site, radial or femoral. At catheter removal, the skin colonization was similar between US and non-US groups (p = 0.69). CONCLUSIONS:Using the largest dataset ever collected from large multi-centric RCTs conducted with relatively consistent insertion and maintenance catheter protocols, we showed that the risk of infectious complications for ACs inserted under US guidance is not superior compared to those inserted without US guidance. Trial registration These studies were registered within ClinicalTrials.gov (numbers NCT01629550 and NCT01189682).

journal_name

Ann Intensive Care

journal_title

Annals of intensive care

authors

Buetti N,Ruckly S,Lucet JC,Bouadma L,Schwebel C,Mimoz O,Timsit JF

doi

10.1186/s13613-020-00705-4

subject

Has Abstract

pub_date

2020-07-08 00:00:00

pages

89

issue

1

issn

2110-5820

pii

10.1186/s13613-020-00705-4

journal_volume

10

pub_type

杂志文章
  • Perioperative statin therapy in cardiac and non-cardiac surgery: a systematic review and meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:The effects of perioperative statin therapy on clinical outcome after cardiac or non-cardiac surgery are controversial. We aimed to assess the association between perioperative statin therapy and postoperative outcome. METHODS:Electronic databases were searched up to May 1, 2018, for randomized controlled t...

    journal_title:Annals of intensive care

    pub_type: 杂志文章,评审

    doi:10.1186/s13613-018-0441-3

    authors: Putzu A,de Carvalho E Silva CMPD,de Almeida JP,Belletti A,Cassina T,Landoni G,Hajjar LA

    更新日期:2018-09-27 00:00:00

  • Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome.

    abstract:BACKGROUND:Despite advances in supportive care, moderate-severe acute respiratory distress syndrome (ARDS) is associated with high mortality rates, and novel therapies to treat this condition are needed. Compelling pre-clinical data from mouse, rat, sheep and ex vivo perfused human lung models support the use of human ...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-014-0022-z

    authors: Liu KD,Wilson JG,Zhuo H,Caballero L,McMillan ML,Fang X,Cosgrove K,Calfee CS,Lee JW,Kangelaris KN,Gotts JE,Rogers AJ,Levitt JE,Wiener-Kronish JP,Delucchi KL,Leavitt AD,McKenna DH,Thompson BT,Matthay MA

    更新日期:2014-07-03 00:00:00

  • Is there still a role for the lung injury score in the era of the Berlin definition ARDS?

    abstract:BACKGROUND:The Lung Injury Score (LIS) remains a commonly utilized measure of lung injury severity though the additive value of LIS to predict ARDS outcomes over the recent Berlin definition of ARDS, which incorporates severity, is not known. METHODS:We tested the association of LIS (in which scores range from 0 to 4,...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/2110-5820-4-4

    authors: Kangelaris KN,Calfee CS,May AK,Zhuo H,Matthay MA,Ware LB

    更新日期:2014-02-18 00:00:00

  • Specific antioxidant properties of human serum albumin.

    abstract:: Human serum albumin (HSA) has been used for a long time as a resuscitation fluid in critically ill patients. It is known to exert several important physiological and pharmacological functions. Among them, the antioxidant properties seem to be of paramount importance as they may be implied in the potential beneficial ...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/2110-5820-3-4

    authors: Taverna M,Marie AL,Mira JP,Guidet B

    更新日期:2013-02-15 00:00:00

  • Associations between tricuspid annular plane systolic excursion to reflect right ventricular function and acute kidney injury in critically ill patients: a SICS-I sub-study.

    abstract:BACKGROUND:Acute kidney injury (AKI) occurs in up to 50% of all critically ill patients and hemodynamic abnormalities are assumed to contribute, but their nature and share is still unclear. We explored the associations between hemodynamic variables, including cardiac index and right ventricular function, and the occurr...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-019-0513-z

    authors: Wiersema R,Koeze J,Hiemstra B,Pettilä V,Perner A,Keus F,van der Horst ICC,SICS Study Group.

    更新日期:2019-03-13 00:00:00

  • Occurrence of marked sepsis-induced immunosuppression in pediatric septic shock: a pilot study.

    abstract:BACKGROUND:While the process of sepsis-induced immunosuppression is now well described in adults, very little information is available on immune functions in pediatric sepsis. The current study investigated this in children with septic shock by performing immunomonitoring, including both innate (monocyte human leukocyt...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-018-0382-x

    authors: Remy S,Kolev-Descamps K,Gossez M,Venet F,Demaret J,Javouhey E,Monneret G

    更新日期:2018-03-13 00:00:00

  • Extracorporeal carbon dioxide removal for acute hypercapnic respiratory failure.

    abstract::In the past, the only treatment of acute exacerbations of obstructive diseases with hypercapnic respiratory failure refractory to medical treatment was invasive mechanical ventilation (IMV). Considerable technical improvements transformed extracorporeal techniques for carbon dioxide removal in an attractive option to ...

    journal_title:Annals of intensive care

    pub_type: 杂志文章,评审

    doi:10.1186/s13613-019-0551-6

    authors: Morales-Quinteros L,Del Sorbo L,Artigas A

    更新日期:2019-07-02 00:00:00

  • Predictors of haemodynamic instability during the changeover of norepinephrine infusion pumps.

    abstract:BACKGROUND:Changeovers of norepinephrine infusion pumps (CNIPs) frequently lead to haemodynamic instability. The aim of this study was to identify risk factors for haemodynamic instability associated with CNIP, independent of the method used to perform the relay. METHODS:We performed a prospective study, in a universi...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-016-0139-3

    authors: Cour M,Bénet T,Hernu R,Simon M,Baudry T,Vanhems P,Argaud L

    更新日期:2016-12-01 00:00:00

  • The protective association of endogenous immunoglobulins against sepsis mortality is restricted to patients with moderate organ failure.

    abstract:BACKGROUND:Pre-evaluation of endogenous immunoglobulin levels is a potential strategy to improve the results of intravenous immunoglobulins in sepsis, but more work has to be done to identify those patients who could benefit the most from this treatment. The objective of this study was to evaluate the impact of endogen...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-017-0268-3

    authors: Martin-Loeches I,Muriel-Bombín A,Ferrer R,Artigas A,Sole-Violan J,Lorente L,Andaluz-Ojeda D,Prina-Mello A,Herrán-Monge R,Suberviola B,Rodriguez-Fernandez A,Merino P,Loza AM,Garcia-Olivares P,Anton E,Tamayo E,Trapiello W,

    更新日期:2017-12-01 00:00:00

  • Breakthrough in cardiac arrest: reports from the 4th Paris International Conference.

    abstract::Jean-Luc Diehl The French Intensive Care Society organized on 5th and 6th June 2014 its 4th "Paris International Conference in Intensive Care", whose principle is to bring together the best international experts on a hot topic in critical care medicine. The 2014 theme was "Breakthrough in cardiac arrest", with many hi...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-015-0064-x

    authors: Kudenchuk PJ,Sandroni C,Drinhaus HR,Böttiger BW,Cariou A,Sunde K,Dworschak M,Taccone FS,Deye N,Friberg H,Laureys S,Ledoux D,Oddo M,Legriel S,Hantson P,Diehl JL,Laterre PF

    更新日期:2015-12-01 00:00:00

  • Erythropoietin in the intensive care unit: beyond treatment of anemia.

    abstract:: Erythropoietin (EPO) is the major hormone stimulating the production and differentiation of red blood cells. EPO is used widely for treating anemia of critical illness or anemia induced by chemotherapy. EPO at pharmacological doses is used in this setting to raise hemoglobin levels (by preventing the apoptosis of ery...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/2110-5820-1-40

    authors: Patel NS,Collino M,Yaqoob MM,Thiemermann C

    更新日期:2011-09-23 00:00:00

  • Evaluation of least significant changes of pulse contour analysis-derived parameters.

    abstract:BACKGROUND:Many maneuvers assessing fluid responsiveness (minifluid challenge, lung recruitment maneuver, end-expiratory occlusion test, passive leg raising) are considered as positive when small variations in cardiac index, stroke volume index, stroke volume variation or pulse pressure variation occur. Pulse contour a...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-019-0590-z

    authors: de Courson H,Ferrer L,Cane G,Verchère E,Sesay M,Nouette-Gaulain K,Biais M

    更新日期:2019-10-11 00:00:00

  • Feasibility of an alternative, physiologic, individualized open-lung approach to high-frequency oscillatory ventilation in children.

    abstract:BACKGROUND:High-frequency oscillatory ventilation (HFOV) is a common but unproven management strategy in paediatric critical care. Oscillator settings have been traditionally guided by patient age and/or weight rather than by lung mechanics, thereby potentially negating any beneficial effects. We have adopted an open-l...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-019-0492-0

    authors: de Jager P,Kamp T,Dijkstra SK,Burgerhof JGM,Markhorst DG,Curley MAQ,Cheifetz IM,Kneyber MCJ

    更新日期:2019-01-18 00:00:00

  • Effect on comfort of administering bubble-humidified or dry oxygen: the Oxyrea non-inferiority randomized study.

    abstract:BACKGROUND:The clinical interest of using bubble humidification of oxygen remains controversial. This study was designed to further explore whether delivering dry oxygen instead of bubble-moistened oxygen had an impact on discomfort of ICU patients. METHODS:This randomized multicenter non-inferiority open trial includ...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-018-0472-9

    authors: Poiroux L,Piquilloud L,Seegers V,Le Roy C,Colonval K,Agasse C,Zinzoni V,Hodebert V,Cambonie A,Saletes J,Bourgeon I,Beloncle F,Mercat A,REVA Network.

    更新日期:2018-12-17 00:00:00

  • The critical care response to a hospital outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection: an observational study.

    abstract:BACKGROUND:Middle East respiratory syndrome coronavirus (MERS-CoV) has caused several hospital outbreaks, including a major outbreak at King Abdulaziz Medical City, a 940-bed tertiary-care hospital in Riyadh, Saudi Arabia (August-September 2015). To learn from our experience, we described the critical care response to ...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-016-0203-z

    authors: Al-Dorzi HM,Aldawood AS,Khan R,Baharoon S,Alchin JD,Matroud AA,Al Johany SM,Balkhy HH,Arabi YM

    更新日期:2016-12-01 00:00:00

  • Estimating mean circulatory filling pressure in clinical practice: a systematic review comparing three bedside methods in the critically ill.

    abstract::The bedside hemodynamic assessment of the critically ill remains challenging since blood volume, arterial-venous interaction and compliance are not measured directly. Mean circulatory filling pressure (Pmcf) is the blood pressure throughout the vascular system at zero flow. Animal studies have shown Pmcf provides info...

    journal_title:Annals of intensive care

    pub_type: 杂志文章,评审

    doi:10.1186/s13613-018-0418-2

    authors: Wijnberge M,Sindhunata DP,Pinsky MR,Vlaar AP,Ouweneel E,Jansen JR,Veelo DP,Geerts BF

    更新日期:2018-06-20 00:00:00

  • Transfusion of platelets, but not of red blood cells, is independently associated with nosocomial infections in the critically ill.

    abstract:BACKGROUND:Red blood cell (RBC) transfusion has been associated with nosocomial infection in the critically ill patients. However, this association may be confounded by length of stay, as prolonged intensive care unit (ICU stay) increases both risk of infection and risk of transfusion. Also, it is not known whether spe...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-016-0173-1

    authors: Engele LJ,Straat M,van Rooijen IHM,de Vooght KMK,Cremer OL,Schultz MJ,Bos LDJ,Juffermans NP,MARS Consortium.

    更新日期:2016-12-01 00:00:00

  • Hypothermic total liquid ventilation after experimental aspiration-associated acute respiratory distress syndrome.

    abstract:BACKGROUND:Ultrafast cooling by total liquid ventilation (TLV) provides potent cardio- and neuroprotection after experimental cardiac arrest. However, this was evaluated in animals with no initial lung injury, whereas out-of-hospital cardiac arrest is frequently associated with early-onset pneumonia, which may lead to ...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-018-0404-8

    authors: Rambaud J,Lidouren F,Sage M,Kohlhauer M,Nadeau M,Fortin-Pellerin É,Micheau P,Zilberstein L,Mongardon N,Ricard JD,Terada M,Bruneval P,Berdeaux A,Ghaleh B,Walti H,Tissier R

    更新日期:2018-05-02 00:00:00

  • Impact of a computer-assisted decision support system (CDSS) on nutrition management in critically ill hematology patients: the NUTCHOCO study (nutritional care in hematology oncologic patients and critical outcome).

    abstract:BACKGROUND:Mortality of critically ill hematology (HM) patients has improved over time. Thus, those patients require an extensive diagnostic workup and the optimal use of available treatments. There are no data regarding nutrition strategy for critically ill HM patients, while nutritional support is crucial for both HM...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-019-0527-6

    authors: Ettori F,Henin A,Zemmour C,Chow-Chine L,Sannini A,Bisbal M,Gonzalez F,Servan L,de Guibert JM,Faucher M,Boher JM,Mokart D

    更新日期:2019-05-07 00:00:00

  • Transpulmonary pressures in obese and non-obese COVID-19 ARDS.

    abstract:BACKGROUND:Data on respiratory mechanics of COVID-19 ARDS patients are scarce. Respiratory mechanics and response to positive expiratory pressure (PEEP) may be different in obese and non-obese patients. METHODS:We investigated esophageal pressure allowing determination of transpulmonary pressures (PL ) and elastances ...

    journal_title:Annals of intensive care

    pub_type: 信件

    doi:10.1186/s13613-020-00745-w

    authors: Mezidi M,Daviet F,Chabert P,Hraiech S,Bitker L,Forel JM,Yonis H,Gragueb I,Dhelft F,Papazian L,Richard JC,Guervilly C

    更新日期:2020-10-01 00:00:00

  • Early mechanical ventilation in patients with Guillain-Barré syndrome at high risk of respiratory failure: a randomized trial.

    abstract:INTRODUCTION:About 30% of patients with Guillain-Barré syndrome become ventilator dependent, of whom roughly 75% develop pneumonia. This trial aimed at assessing the impact of early mechanical ventilation (EMV) on pneumonia occurrence in GBS patients. We hypothesize that EMV will reduce the incidence of pneumonia. MET...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-020-00742-z

    authors: Melone MA,Heming N,Meng P,Mompoint D,Aboab J,Clair B,Salomon J,Sharshar T,Orlikowski D,Chevret S,Annane D

    更新日期:2020-09-30 00:00:00

  • Bedside prediction of intradialytic hemodynamic instability in critically ill patients: the SOCRATE study.

    abstract:BACKGROUND:Despite improvements in intermittent hemodialysis management, intradialytic hemodynamic instability (IHI) remains a common issue that could account for increased mortality and delayed renal recovery. However, predictive factors of IHI remain poorly explored. The objective of this study was to evaluate the re...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-020-00663-x

    authors: Bigé N,Lavillegrand JR,Dang J,Attias P,Deryckere S,Joffre J,Dubée V,Preda G,Dumas G,Hariri G,Pichereau C,Baudel JL,Guidet B,Maury E,Boelle PY,Ait-Oufella H

    更新日期:2020-04-22 00:00:00

  • Effects of chloride content of intravenous crystalloid solutions in critically ill adult patients: a meta-analysis with trial sequential analysis of randomized trials.

    abstract:BACKGROUND:Intravenous crystalloid solutions are administered commonly for critically ill patients. We performed this meta-analysis of randomized trials with trial sequential analysis (TSA) to evaluate effects of chloride content of intravenous crystalloid solutions on clinical outcomes among critically ill adult patie...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-019-0506-y

    authors: Xue M,Zhang X,Liu F,Chang W,Xie J,Xu J,Yang Y,Qiu H

    更新日期:2019-02-13 00:00:00

  • Accuracy of P0.1 measurements performed by ICU ventilators: a bench study.

    abstract:BACKGROUND:Occlusion pressure at 100 ms (P0.1), defined as the negative pressure measured 100 ms after the initiation of an inspiratory effort performed against a closed respiratory circuit, has been shown to be well correlated with central respiratory drive and respiratory effort. Automated P0.1 measurement is availab...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-019-0576-x

    authors: Beloncle F,Piquilloud L,Olivier PY,Vuillermoz A,Yvin E,Mercat A,Richard JC

    更新日期:2019-09-13 00:00:00

  • Knockout of interleukin-17A protects against sepsis-associated acute kidney injury.

    abstract:BACKGROUND:Sepsis-associated acute kidney injury (SA-AKI) is an independent risk factor for death in patients with sepsis, but treatment for it is limited. To improve the diagnosis and treatment of SA-AKI, we must first understand its pathogenesis. Recently, interleukin (IL)-17A has been shown to be associated with the...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-016-0157-1

    authors: Luo CJ,Luo F,Zhang L,Xu Y,Cai GY,Fu B,Feng Z,Sun XF,Chen XM

    更新日期:2016-12-01 00:00:00

  • Relation between presence of extended-spectrum β-lactamase-producing Enterobacteriaceae in systematic rectal swabs and respiratory tract specimens in ICU patients.

    abstract:BACKGROUND:The choice of empirical antimicrobial therapy for pneumonia in intensive care unit (ICU) is a challenge, since pneumonia is often related to multidrug-resistant pathogens, particularly extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E). To prevent the overuse of broad-spectrum antimicrobial ...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-017-0237-x

    authors: Carbonne H,Le Dorze M,Bourrel AS,Poupet H,Poyart C,Cambau E,Mira JP,Charpentier J,Amarsy R

    更新日期:2017-12-01 00:00:00

  • Ten-year trends in intensive care admissions for respiratory infections in the elderly.

    abstract:BACKGROUND:The consequences of the ageing population concerning ICU hospitalisation need to be adequately described. We believe that this discussion should be disease specific. A focus on respiratory infections is of particular interest, because it is strongly associated with old age. Our objective was to assess trends...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-018-0430-6

    authors: Laporte L,Hermetet C,Jouan Y,Gaborit C,Rouve E,Shea KM,Si-Tahar M,Dequin PF,Grammatico-Guillon L,Guillon A

    更新日期:2018-08-15 00:00:00

  • Urea for treatment of acute SIADH in patients with subarachnoid hemorrhage: a single-center experience.

    abstract:BACKGROUND:Hyponatremia occurring as a result of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) or cerebral salt wasting syndrome is a common complication in patients with subarachnoid hemorrhage (SAH). The efficacy and safety of urea as treatment for SIADH-induced hyponatremia has not been report...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/2110-5820-2-13

    authors: Pierrakos C,Taccone FS,Decaux G,Vincent JL,Brimioulle S

    更新日期:2012-05-30 00:00:00

  • Driving pressure during proportional assist ventilation: an observational study.

    abstract:BACKGROUND:During passive mechanical ventilation, the driving pressure of the respiratory system is an important mediator of ventilator-induced lung injury. Monitoring of driving pressure during assisted ventilation, similar to controlled ventilation, could be a tool to identify patients at risk of ventilator-induced l...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-018-0477-4

    authors: Vaporidi K,Psarologakis C,Proklou A,Pediaditis E,Akoumianaki E,Koutsiana E,Chytas A,Chouvarda I,Kondili E,Georgopoulos D

    更新日期:2019-01-03 00:00:00

  • Important drug classes associated with potential drug-drug interactions in critically ill patients: highlights for cardiothoracic intensivists.

    abstract:BACKGROUND:Patients in the intensive care unit (ICU) are more prone to drug-drug interactions (DDIs). The software and charts that indicate all interactions may not be proper for clinical usage. This study aimed to identify the main drug classes associated with clinically significant DDIs in cardiothoracic ICU and cate...

    journal_title:Annals of intensive care

    pub_type: 杂志文章

    doi:10.1186/s13613-015-0086-4

    authors: Baniasadi S,Farzanegan B,Alehashem M

    更新日期:2015-12-01 00:00:00