Extracorporeal carbon dioxide removal for acute hypercapnic respiratory failure.

abstract：:Anemia and red blood cell (RBC) transfusion occur frequently in hospitalized patients with cardiac disease. In this narrative review, we report the epidemiology of anemia and RBC transfusion in hospitalized adults and children (excluding premature neonates) with cardiac disease, and on the outcome of anemic and transf...

journal_title：Annals of intensive care

authors： Du Pont-Thibodeau G,Harrington K,Lacroix J

更新日期：2014-06-02 00:00:00

abstract：BACKGROUND:The data on incidence, clinical presentation, and outcomes of ventilator-associated pneumonia (VAP) in patients with severe coronavirus disease 2019 (COVID-19) pneumonia requiring mechanical ventilation (MV) are limited. We performed this retrospective cohort study to assess frequency, clinical characteristi...

journal_title：Annals of intensive care

authors： Luyt CE,Sahnoun T,Gautier M,Vidal P,Burrel S,Pineton de Chambrun M,Chommeloux J,Desnos C,Arzoine J,Nieszkowska A,Bréchot N,Schmidt M,Hekimian G,Boutolleau D,Robert J,Combes A,Chastre J

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Despite improvements in intermittent hemodialysis management, intradialytic hemodynamic instability (IHI) remains a common issue that could account for increased mortality and delayed renal recovery. However, predictive factors of IHI remain poorly explored. The objective of this study was to evaluate the re...

journal_title：Annals of intensive care

authors： Bigé N,Lavillegrand JR,Dang J,Attias P,Deryckere S,Joffre J,Dubée V,Preda G,Dumas G,Hariri G,Pichereau C,Baudel JL,Guidet B,Maury E,Boelle PY,Ait-Oufella H

更新日期：2020-04-22 00:00:00

abstract：: Human serum albumin (HSA) has been used for a long time as a resuscitation fluid in critically ill patients. It is known to exert several important physiological and pharmacological functions. Among them, the antioxidant properties seem to be of paramount importance as they may be implied in the potential beneficial ...

journal_title：Annals of intensive care

authors： Taverna M,Marie AL,Mira JP,Guidet B

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:Intensivists' clinical decision making pursues two main goals for patients: to decrease mortality and to improve quality of life and functional status in survivors. Patient-important outcomes are gaining wide acceptance in most fields of clinical research. We sought to systematically review how well patient-...

journal_title：Annals of intensive care

authors： Gaudry S,Messika J,Ricard JD,Guillo S,Pasquet B,Dubief E,Boukertouta T,Dreyfuss D,Tubach F

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Middle East respiratory syndrome coronavirus (MERS-CoV) has caused several hospital outbreaks, including a major outbreak at King Abdulaziz Medical City, a 940-bed tertiary-care hospital in Riyadh, Saudi Arabia (August-September 2015). To learn from our experience, we described the critical care response to ...

journal_title：Annals of intensive care

authors： Al-Dorzi HM,Aldawood AS,Khan R,Baharoon S,Alchin JD,Matroud AA,Al Johany SM,Balkhy HH,Arabi YM

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:While the process of sepsis-induced immunosuppression is now well described in adults, very little information is available on immune functions in pediatric sepsis. The current study investigated this in children with septic shock by performing immunomonitoring, including both innate (monocyte human leukocyt...

journal_title：Annals of intensive care

authors： Remy S,Kolev-Descamps K,Gossez M,Venet F,Demaret J,Javouhey E,Monneret G

更新日期：2018-03-13 00:00:00

abstract：:Although chest X-ray remains a fundamental lung imaging technique, through the years, CT scan has significantly improved our knowledge of the pathophysiological process and currently is the reference lung imaging tool for both a visual and quantitative computer-based analysis. The application of lung CT in the early p...

journal_title：Annals of intensive care

authors： Chiumello D,Formenti P,Coppola S

更新日期：2019-01-22 00:00:00

abstract：BACKGROUND:cRel, a subunit of NF-κB, is implicated in the inflammatory response observed in autoimmune disease. Hence, knocked-out mice for cRel had a significantly higher mortality, providing new and important functions of cRel in the physiopathology of septic shock. Whether genetic variants in the human REL gene are ...

journal_title：Annals of intensive care

authors： Toubiana J,Courtine E,Tores F,Asfar P,Daubin C,Rousseau C,Ouaaz F,Marin N,Cariou A,Chiche JD,Mira JP

更新日期：2016-12-01 00:00:00

abstract：: Multiple experimental and human trials have shown that microcirculatory alterations are frequent in sepsis. In this review, we discuss the characteristics of these alterations, the various mechanisms potentially involved, and the implications for therapy. Sepsis-induced microvascular alterations are characterized by ...

journal_title：Annals of intensive care

authors： De Backer D,Donadello K,Taccone FS,Ospina-Tascon G,Salgado D,Vincent JL

更新日期：2011-07-19 00:00:00

abstract：:Animal experiments are widely used in preclinical medical research with the goal of disease modeling and exploration of novel therapeutic approaches. In the context of sepsis and septic shock, the translation into clinical practice has been disappointing. Classical animal models of septic shock usually involve one-sex...

journal_title：Annals of intensive care

authors： Guillon A,Preau S,Aboab J,Azabou E,Jung B,Silva S,Textoris J,Uhel F,Vodovar D,Zafrani L,de Prost N,Radermacher P,Translational Research Committee of the French Intensive Care Society (Société de Réanimation de Langue Française).

更新日期：2019-06-10 00:00:00

abstract：BACKGROUND:During passive mechanical ventilation, the driving pressure of the respiratory system is an important mediator of ventilator-induced lung injury. Monitoring of driving pressure during assisted ventilation, similar to controlled ventilation, could be a tool to identify patients at risk of ventilator-induced l...

journal_title：Annals of intensive care

authors： Vaporidi K,Psarologakis C,Proklou A,Pediaditis E,Akoumianaki E,Koutsiana E,Chytas A,Chouvarda I,Kondili E,Georgopoulos D

更新日期：2019-01-03 00:00:00

abstract：:This review examines the available evidence for targeting a specific mean arterial pressure (MAP) in sepsis resuscitation. The clinical data suggest that targeting an MAP of 65-70 mmHg in patients with septic shock who do not have chronic hypertension is a reasonable first approximation. Whereas in patients with chron...

journal_title：Annals of intensive care

authors： Kato R,Pinsky MR

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Optimal anti-bacterial activity of meropenem requires maintenance of its plasma concentration (Cp) above the minimum inhibitory concentration (MIC) of the pathogen for at least 40% of the dosing interval (fT > MIC > 40). We aimed to determine whether a 3-h extended infusion (EI) of meropenem achieves fT > MI...

journal_title：Annals of intensive care

authors： Kothekar AT,Divatia JV,Myatra SN,Patil A,Nookala Krishnamurthy M,Maheshwarappa HM,Siddiqui SS,Gurjar M,Biswas S,Gota V

更新日期：2020-01-10 00:00:00

abstract：BACKGROUND:We performed a meta-analysis of randomized controlled trials (RCTs) to determine if daily bathing with chlorhexidine decreased hospital-acquired BSIs in critically ill patients. METHODS:We searched the MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases to identify randomized contr...

journal_title：Annals of intensive care

authors： Choi EY,Park DA,Kim HJ,Park J

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown. The aim of our study was to evaluate the effect of an intraoperative goal-directed fluid restriction (GDFR) strategy on the postoperative outcome of high-risk patients undergoing brain sur...

journal_title：Annals of intensive care

authors： Luo J,Xue J,Liu J,Liu B,Liu L,Chen G

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Hyperglycaemia is commonplace in the adult intensive care unit (ICU), associated with increased morbidity and mortality. Effective glycaemic control (GC) can reduce morbidity and mortality, but has proven difficult. STAR is a proven, effective model-based ICU GC protocol that uniquely maintains normo-glycaem...

journal_title：Annals of intensive care

authors： Stewart KW,Chase JG,Pretty CG,Shaw GM

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:Empirical antimicrobial therapy (EAT) is a challenge for community-acquired, hospital-acquired and ventilator-associated pneumonia, particularly in the context of the increasing occurrence of third-generation cephalosporin-resistant Enterobacterales (3GCR-E), including extended-spectrum beta-lactamase Entero...

journal_title：Annals of intensive care

authors： Elsa M,Matthieu LD,De Ponfilly Gauthier P,Hanaa B,Rishma A,Emmanuelle C,Benjamin S,Glenn CB,Hervé J

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:Patients in the intensive care unit (ICU) are more prone to drug-drug interactions (DDIs). The software and charts that indicate all interactions may not be proper for clinical usage. This study aimed to identify the main drug classes associated with clinically significant DDIs in cardiothoracic ICU and cate...

journal_title：Annals of intensive care

authors： Baniasadi S,Farzanegan B,Alehashem M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Middle East respiratory syndrome (MERS) is caused by a coronavirus (MERS-CoV) and is characterized by hypoxemic respiratory failure. The objective of this study is to compare the outcomes of MERS-CoV patients before and after the availability of extracorporeal membrane oxygenation (ECMO) as a rescue therapy ...

journal_title：Annals of intensive care

authors： Alshahrani MS,Sindi A,Alshamsi F,Al-Omari A,El Tahan M,Alahmadi B,Zein A,Khatani N,Al-Hameed F,Alamri S,Abdelzaher M,Alghamdi A,Alfousan F,Tash A,Tashkandi W,Alraddadi R,Lewis K,Badawee M,Arabi YM,Fan E,Alhazzani

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:Venous thromboembolism (VTE) is one of the most common preventable causes of in-hospital death in trauma patients surviving their injuries. We assessed the prevalence, incidence and risk factors for deep venous thrombosis (DVT) and pulmonary embolism (PE) in critically ill trauma patients, in the setting of ...

journal_title：Annals of intensive care

authors： Hamada SR,Espina C,Guedj T,Buaron R,Harrois A,Figueiredo S,Duranteau J

更新日期：2017-09-12 00:00:00

abstract：BACKGROUND:Despite advances in the management of bloodstream infections (BSI) caused by Candida spp., the mortality still remains high in critically ill patients. The worldwide epidemiology of yeast-related BSI is subject to changing species distribution and resistance patterns, challenging antifungal treatment strateg...

journal_title：Annals of intensive care

authors： Schroeder M,Weber T,Denker T,Winterland S,Wichmann D,Rohde H,Ozga AK,Fischer M,Kluge S

更新日期：2020-10-16 00:00:00

abstract：: Cancer is a leading cause of death in children. In the past decades, there has been a marked increase in overall survival of children with cancer. However, children whose treatment includes hematopoietic stem cell transplantation still represent a subpopulation with a higher risk of mortality. These improvements in m...

journal_title：Annals of intensive care

authors： Demaret P,Pettersen G,Hubert P,Teira P,Emeriaud G

更新日期：2012-06-12 00:00:00

abstract：BACKGROUND:Optimal sedation and analgesia is a challenge in paediatric intensive care units (PICU) because of difficulties in scoring systems and specific metabolism inducing tolerance and withdrawal. Excessive sedation is associated with prolonged mechanical ventilation and hospitalisation. Adult and paediatric data s...

journal_title：Annals of intensive care

authors： Dreyfus L,Javouhey E,Denis A,Touzet S,Bordet F

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:We assessed the association of intravenous insulin and glucose infusion with intensive care unit (ICU) and hospital mortality. METHODS:For this retrospective association study, we used data from all patients admitted to a medical-surgical ICU between January 2012 and September 2017. We excluded patients adm...

journal_title：Annals of intensive care

authors： van Steen SC,Rijkenberg S,van der Voort PHJ,DeVries JH

更新日期：2019-02-11 00:00:00

abstract：: Erythropoietin (EPO) is the major hormone stimulating the production and differentiation of red blood cells. EPO is used widely for treating anemia of critical illness or anemia induced by chemotherapy. EPO at pharmacological doses is used in this setting to raise hemoglobin levels (by preventing the apoptosis of ery...

journal_title：Annals of intensive care

authors： Patel NS,Collino M,Yaqoob MM,Thiemermann C

更新日期：2011-09-23 00:00:00

abstract：BACKGROUND:Lactate is a robust prognostic marker for the outcome of critically ill patients. Several small studies reported that metformin users have higher lactate levels at ICU admission without a concomitant increase in mortality. However, this has not been investigated in a larger cohort. We aimed to determine whet...

journal_title：Annals of intensive care

authors： Posma RA,Frøslev T,Jespersen B,van der Horst ICC,Touw DJ,Thomsen RW,Nijsten MW,Christiansen CF

更新日期：2020-03-26 00:00:00

abstract：:Although improving, the mortality from septic shock still remains high despite increased international awareness. As a consequence, much effort has focused on alternative treatment strategies in an effort to improve outcomes. The application of blood purification therapies to improve immune homeostasis has been sugges...

journal_title：Annals of intensive care

authors： Honore PM,Hoste E,Molnár Z,Jacobs R,Joannes-Boyau O,Malbrain MLNG,Forni LG

更新日期：2019-05-14 00:00:00

abstract：BACKGROUND:Critical illness has detrimental effects on the diaphragm, but the impact of critical illness on other major muscles of the respiratory pump has been largely neglected. This study aimed to determine the impact of critical illness on the most important muscles of the respiratory muscle pump, especially on the...

journal_title：Annals of intensive care

authors： IJland MM,Lemson J,van der Hoeven JG,Heunks LMA

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:The initial management of a trauma patient is a critical and demanding period. The use of extended focused assessment sonography for trauma (eFAST) has become more prevalent in trauma rooms, raising questions about the real "added value" of chest X-rays (CXRs) and pelvic X-rays (PXR), particularly in haemody...

journal_title：Annals of intensive care

authors： Hamada SR,Delhaye N,Kerever S,Harrois A,Duranteau J

更新日期：2016-12-01 00:00:00