Cytokine removal in human septic shock: Where are we and where are we going?

abstract：BACKGROUND:SARS coronavirus 2 (SARS-CoV-2) is responsible for high morbidity and mortality worldwide, mostly due to the exacerbated inflammatory response observed in critically ill patients. However, little is known about the kinetics of the systemic immune response and its association with survival in SARS-CoV-2+ pati...

journal_title：Annals of intensive care

authors： Lavillegrand JR,Garnier M,Spaeth A,Mario N,Hariri G,Pilon A,Berti E,Fieux F,Thietart S,Urbina T,Turpin M,Darrivière L,Fartoukh M,Verdonk F,Dumas G,Tedgui A,Guidet B,Maury E,Chantran Y,Voiriot G,Ait-Oufella H

更新日期：2021-01-13 00:00:00

abstract：BACKGROUND:Glucose control is an important issue in post-operative patients. The objective here was to compare two insulin infusion lines by syringe pumps to assess the impact of medical devices on glycaemic variability in surgical patients under intensive insulin therapy. This open, prospective, single-centre randomis...

journal_title：Annals of intensive care

authors： Genay S,Décaudin B,Ethgen S,Alluin A,Babol E,Labreuche J,Behal H,Vantyghem MC,Odou P,Lebuffe G

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Empirical antimicrobial therapy (EAT) is a challenge for community-acquired, hospital-acquired and ventilator-associated pneumonia, particularly in the context of the increasing occurrence of third-generation cephalosporin-resistant Enterobacterales (3GCR-E), including extended-spectrum beta-lactamase Entero...

journal_title：Annals of intensive care

authors： Elsa M,Matthieu LD,De Ponfilly Gauthier P,Hanaa B,Rishma A,Emmanuelle C,Benjamin S,Glenn CB,Hervé J

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:During passive mechanical ventilation, the driving pressure of the respiratory system is an important mediator of ventilator-induced lung injury. Monitoring of driving pressure during assisted ventilation, similar to controlled ventilation, could be a tool to identify patients at risk of ventilator-induced l...

journal_title：Annals of intensive care

authors： Vaporidi K,Psarologakis C,Proklou A,Pediaditis E,Akoumianaki E,Koutsiana E,Chytas A,Chouvarda I,Kondili E,Georgopoulos D

更新日期：2019-01-03 00:00:00

abstract：BACKGROUND:Aneurysmal subarachnoid hemorrhage (SAH) is a serious condition associated with high mortality rates and long-term disability. We investigated the impact of fluid balance on neurologic outcome after adjustment for possible confounders related to intensive care therapy and extra-cerebral organ failure during ...

journal_title：Annals of intensive care

authors： Sakr Y,Dünisch P,Santos C,Matthes L,Zeidan M,Reinhart K,Kalff R,Ewald C

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Intensivists' clinical decision making pursues two main goals for patients: to decrease mortality and to improve quality of life and functional status in survivors. Patient-important outcomes are gaining wide acceptance in most fields of clinical research. We sought to systematically review how well patient-...

journal_title：Annals of intensive care

authors： Gaudry S,Messika J,Ricard JD,Guillo S,Pasquet B,Dubief E,Boukertouta T,Dreyfuss D,Tubach F

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Hyponatremia occurring as a result of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) or cerebral salt wasting syndrome is a common complication in patients with subarachnoid hemorrhage (SAH). The efficacy and safety of urea as treatment for SIADH-induced hyponatremia has not been report...

journal_title：Annals of intensive care

authors： Pierrakos C,Taccone FS,Decaux G,Vincent JL,Brimioulle S

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Optimal sedation and analgesia is a challenge in paediatric intensive care units (PICU) because of difficulties in scoring systems and specific metabolism inducing tolerance and withdrawal. Excessive sedation is associated with prolonged mechanical ventilation and hospitalisation. Adult and paediatric data s...

journal_title：Annals of intensive care

authors： Dreyfus L,Javouhey E,Denis A,Touzet S,Bordet F

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The importance of intra-abdominal pressure (IAP) and abdominal perfusion pressure (APP) in cirrhotic patients with septic shock is not well studied. We evaluated the relationship between IAP and APP and outcomes of cirrhotic septic patients, and assessed the ability of these measures compared to other common...

journal_title：Annals of intensive care

authors： Al-Dorzi HM,Tamim HM,Rishu AH,Aljumah A,Arabi YM

更新日期：2012-07-05 00:00:00

abstract：BACKGROUND:We performed a meta-analysis of randomized controlled trials (RCTs) to determine if daily bathing with chlorhexidine decreased hospital-acquired BSIs in critically ill patients. METHODS:We searched the MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases to identify randomized contr...

journal_title：Annals of intensive care

authors： Choi EY,Park DA,Kim HJ,Park J

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The clinical interest of using bubble humidification of oxygen remains controversial. This study was designed to further explore whether delivering dry oxygen instead of bubble-moistened oxygen had an impact on discomfort of ICU patients. METHODS:This randomized multicenter non-inferiority open trial includ...

journal_title：Annals of intensive care

authors： Poiroux L,Piquilloud L,Seegers V,Le Roy C,Colonval K,Agasse C,Zinzoni V,Hodebert V,Cambonie A,Saletes J,Bourgeon I,Beloncle F,Mercat A,REVA Network.

更新日期：2018-12-17 00:00:00

abstract：INTRODUCTION:About 30% of patients with Guillain-Barré syndrome become ventilator dependent, of whom roughly 75% develop pneumonia. This trial aimed at assessing the impact of early mechanical ventilation (EMV) on pneumonia occurrence in GBS patients. We hypothesize that EMV will reduce the incidence of pneumonia. MET...

journal_title：Annals of intensive care

authors： Melone MA,Heming N,Meng P,Mompoint D,Aboab J,Clair B,Salomon J,Sharshar T,Orlikowski D,Chevret S,Annane D

更新日期：2020-09-30 00:00:00

abstract：BACKGROUND:The choice of empirical antimicrobial therapy for pneumonia in intensive care unit (ICU) is a challenge, since pneumonia is often related to multidrug-resistant pathogens, particularly extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E). To prevent the overuse of broad-spectrum antimicrobial ...

journal_title：Annals of intensive care

authors： Carbonne H,Le Dorze M,Bourrel AS,Poupet H,Poyart C,Cambau E,Mira JP,Charpentier J,Amarsy R

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Many maneuvers assessing fluid responsiveness (minifluid challenge, lung recruitment maneuver, end-expiratory occlusion test, passive leg raising) are considered as positive when small variations in cardiac index, stroke volume index, stroke volume variation or pulse pressure variation occur. Pulse contour a...

journal_title：Annals of intensive care

authors： de Courson H,Ferrer L,Cane G,Verchère E,Sesay M,Nouette-Gaulain K,Biais M

更新日期：2019-10-11 00:00:00

abstract：BACKGROUND:Data on respiratory mechanics of COVID-19 ARDS patients are scarce. Respiratory mechanics and response to positive expiratory pressure (PEEP) may be different in obese and non-obese patients. METHODS:We investigated esophageal pressure allowing determination of transpulmonary pressures (PL ) and elastances ...

journal_title：Annals of intensive care

authors： Mezidi M,Daviet F,Chabert P,Hraiech S,Bitker L,Forel JM,Yonis H,Gragueb I,Dhelft F,Papazian L,Richard JC,Guervilly C

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Despite advances in supportive care, moderate-severe acute respiratory distress syndrome (ARDS) is associated with high mortality rates, and novel therapies to treat this condition are needed. Compelling pre-clinical data from mouse, rat, sheep and ex vivo perfused human lung models support the use of human ...

journal_title：Annals of intensive care

authors： Liu KD,Wilson JG,Zhuo H,Caballero L,McMillan ML,Fang X,Cosgrove K,Calfee CS,Lee JW,Kangelaris KN,Gotts JE,Rogers AJ,Levitt JE,Wiener-Kronish JP,Delucchi KL,Leavitt AD,McKenna DH,Thompson BT,Matthay MA

更新日期：2014-07-03 00:00:00

abstract：BACKGROUND:Middle East respiratory syndrome (MERS) is caused by a coronavirus (MERS-CoV) and is characterized by hypoxemic respiratory failure. The objective of this study is to compare the outcomes of MERS-CoV patients before and after the availability of extracorporeal membrane oxygenation (ECMO) as a rescue therapy ...

journal_title：Annals of intensive care

authors： Alshahrani MS,Sindi A,Alshamsi F,Al-Omari A,El Tahan M,Alahmadi B,Zein A,Khatani N,Al-Hameed F,Alamri S,Abdelzaher M,Alghamdi A,Alfousan F,Tash A,Tashkandi W,Alraddadi R,Lewis K,Badawee M,Arabi YM,Fan E,Alhazzani

更新日期：2018-01-10 00:00:00

abstract：: Human serum albumin (HSA) has been used for a long time as a resuscitation fluid in critically ill patients. It is known to exert several important physiological and pharmacological functions. Among them, the antioxidant properties seem to be of paramount importance as they may be implied in the potential beneficial ...

journal_title：Annals of intensive care

authors： Taverna M,Marie AL,Mira JP,Guidet B

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:Despite advances in the management of bloodstream infections (BSI) caused by Candida spp., the mortality still remains high in critically ill patients. The worldwide epidemiology of yeast-related BSI is subject to changing species distribution and resistance patterns, challenging antifungal treatment strateg...

journal_title：Annals of intensive care

authors： Schroeder M,Weber T,Denker T,Winterland S,Wichmann D,Rohde H,Ozga AK,Fischer M,Kluge S

更新日期：2020-10-16 00:00:00

abstract：BACKGROUND:Acute respiratory distress syndrome (ARDS) patients may present impaired in lung function and structure after hospital discharge that may be related to mechanical ventilation strategy. The aim of this study was to evaluate the association between functional and structural lung impairment, N-terminal-peptide ...

journal_title：Annals of intensive care

authors： Toufen Junior C,De Santis Santiago RR,Hirota AS,Carvalho ARS,Gomes S,Amato MBP,Carvalho CRR

更新日期：2018-12-07 00:00:00

abstract：BACKGROUND:Pre-evaluation of endogenous immunoglobulin levels is a potential strategy to improve the results of intravenous immunoglobulins in sepsis, but more work has to be done to identify those patients who could benefit the most from this treatment. The objective of this study was to evaluate the impact of endogen...

journal_title：Annals of intensive care

authors： Martin-Loeches I,Muriel-Bombín A,Ferrer R,Artigas A,Sole-Violan J,Lorente L,Andaluz-Ojeda D,Prina-Mello A,Herrán-Monge R,Suberviola B,Rodriguez-Fernandez A,Merino P,Loza AM,Garcia-Olivares P,Anton E,Tamayo E,Trapiello W,

更新日期：2017-12-01 00:00:00

abstract：:Although chest X-ray remains a fundamental lung imaging technique, through the years, CT scan has significantly improved our knowledge of the pathophysiological process and currently is the reference lung imaging tool for both a visual and quantitative computer-based analysis. The application of lung CT in the early p...

journal_title：Annals of intensive care

authors： Chiumello D,Formenti P,Coppola S

更新日期：2019-01-22 00:00:00

abstract：UNLABELLED: BACKGROUND:A history of prolonged and excessive consumption of alcohol increases the risk for infections. The goal of this study was to investigate circulating white blood cells (WBC) differentiated by flow cytometry and neutrophil CD64 expression in excessive alcohol drinkers versus abstinent or moderate ...

journal_title：Annals of intensive care

authors： Gacouin A,Roussel M,Gros A,Sauvadet E,Uhel F,Chimot L,Marque S,Camus C,Fest T,Le Tulzo Y

更新日期：2012-12-31 00:00:00

abstract：BACKGROUND:The echocardiography working group of the European Society of Intensive Care Medicine recognized the need to provide structured guidance for future CCE research methodology and reporting based on a systematic appraisal of the current literature. Here is reported this systematic appraisal. METHODS:We conduct...

journal_title：Annals of intensive care

authors： Huang S,Sanfilippo F,Herpain A,Balik M,Chew M,Clau-Terré F,Corredor C,De Backer D,Fletcher N,Geri G,Mekontso-Dessap A,McLean A,Morelli A,Orde S,Petrinic T,Slama M,van der Horst ICC,Vignon P,Mayo P,Vieillard-Baron A

更新日期：2020-04-25 00:00:00

abstract：BACKGROUND:Among intensive care unit (ICU) patients with acute respiratory distress syndrome (ARDS), apart from acute cor pulmonale (ACP), the frequency and prognostic impact of basic critical care echocardiography (BCCE) abnormalities are not well defined. METHODS:Observational study of patients with ARDS, admitted f...

journal_title：Annals of intensive care

authors： See KC,Ng J,Siow WT,Ong V,Phua J

更新日期：2017-12-19 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) occurs in up to 50% of all critically ill patients and hemodynamic abnormalities are assumed to contribute, but their nature and share is still unclear. We explored the associations between hemodynamic variables, including cardiac index and right ventricular function, and the occurr...

journal_title：Annals of intensive care

authors： Wiersema R,Koeze J,Hiemstra B,Pettilä V,Perner A,Keus F,van der Horst ICC,SICS Study Group.

更新日期：2019-03-13 00:00:00

abstract：BACKGROUND:Criteria for the Sepsis-3 definition of septic shock include vasopressor treatment to maintain a mean arterial pressure > 65 mmHg and a lactate concentration > 2 mmol/L. The impact of hyperoxia in patients with septic shock using these criteria is unknown. METHODS:A post hoc analysis was performed of the HY...

journal_title：Annals of intensive care

authors： Demiselle J,Wepler M,Hartmann C,Radermacher P,Schortgen F,Meziani F,Singer M,Seegers V,Asfar P,HYPER2S investigators.

更新日期：2018-09-17 00:00:00

abstract：BACKGROUND:Critical illness has detrimental effects on the diaphragm, but the impact of critical illness on other major muscles of the respiratory pump has been largely neglected. This study aimed to determine the impact of critical illness on the most important muscles of the respiratory muscle pump, especially on the...

journal_title：Annals of intensive care

authors： IJland MM,Lemson J,van der Hoeven JG,Heunks LMA

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:Patients in the intensive care unit (ICU) are more prone to drug-drug interactions (DDIs). The software and charts that indicate all interactions may not be proper for clinical usage. This study aimed to identify the main drug classes associated with clinically significant DDIs in cardiothoracic ICU and cate...

journal_title：Annals of intensive care

authors： Baniasadi S,Farzanegan B,Alehashem M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:While the process of sepsis-induced immunosuppression is now well described in adults, very little information is available on immune functions in pediatric sepsis. The current study investigated this in children with septic shock by performing immunomonitoring, including both innate (monocyte human leukocyt...

journal_title：Annals of intensive care

authors： Remy S,Kolev-Descamps K,Gossez M,Venet F,Demaret J,Javouhey E,Monneret G

更新日期：2018-03-13 00:00:00