Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients.

abstract：OBJECTIVE:Recently, 14-3-3 zeta protein was identified as a potential serum biomarker of epithelial ovarian cancer (EOC). The goal of this study was to investigate the clinical potential of 14-3-3 zeta protein for monitoring EOC progression compared with CA-125 and HE4. DESIGN:Prospective follow-up study. SETTING:Uni...

journal_title：Journal of ovarian research

authors： Hatzipetros I,Gocze P,Koszegi T,Jaray A,Szereday L,Polgar B,Farkas N,Farkas B

更新日期：2013-11-15 00:00:00

abstract：BACKGROUND:Ovarian cancer is the leading cause of gynecological cancer-related mortality. The novel oncogene S100A10 has been reported to be involved in cancer cell proliferation, invasion and metastasis. The role of S100A10 in ovarian cancer has not been well studied and the effect of S100A10 on chemotherapy remains u...

journal_title：Journal of ovarian research

authors： Wang L,Yan W,Li X,Liu Z,Tian T,Chen T,Zou L,Cui Z

更新日期：2019-11-18 00:00:00

abstract：:Ovarian cystic tumors with a mural nodule are a rare entity. We report a case of a mural nodule of anaplastic spindle cell carcinoma in an ovarian mucinous cystic tumor of borderline malignancy. The patient was a 45-years-old Japanese woman who presented with an ovarian cyst. She suffered from mature cystic teratoma o...

journal_title：Journal of ovarian research

authors： Yamazaki H,Matsuzawa A,Shoda T,Iguchi H,Kyushima N

更新日期：2013-12-05 00:00:00

abstract：BACKGROUND:This study aimed to identify the clinical and pathological characteristics and the possible prognostic factors for Chinese patients with early-stage ovarian endometrioid carcinoma. METHODS:The present study reviewed the medical records of patients who received initial treatment and a postoperative pathologi...

journal_title：Journal of ovarian research

authors： Zhao Y,Wang S,Qu YM,Ji YT,Shen K,Lang JH

更新日期：2017-09-18 00:00:00

abstract：INTRODUCTION:The use of patient reported outcome measures (PROMs) has increased during the past decade, and the focus on how to use them has resulted in a more proactive application. Studies have shown that proactive use of PROMs during treatment improves patient-clinician communication, leads to better symptom managem...

journal_title：Journal of ovarian research

authors： Kargo AS,Coulter A,Jensen PT,Steffensen KD

更新日期：2019-07-15 00:00:00

abstract：BACKGROUND:Because higher survival of follicles during the freezing/thawing procedure improves the quality of cryopreserved tissue reimplanted after oncological therapies, defining an optimal method for human ovarian tissue cryopreservation remains a major issue in this field. One option to improve the cryopreservation...

journal_title：Journal of ovarian research

authors： Scheiner D,Bracone G,Imesch P,Fink D,Hehl J,Imthurn B

更新日期：2016-09-26 00:00:00

abstract：BACKGROUND:The mechanisms regulating the function and regression of the corpus luteum (CL) have not yet been elucidated in detail. The regressed CL of cows was previously reported to be filled with unusual vessels like arteriovenous anastomosis (AVA); however how these vessels are being established during luteolysis re...

journal_title：Journal of ovarian research

authors： Nio-Kobayashi J,Miyazaki K,Hashiba K,Okuda K,Iwanaga T

更新日期：2016-10-19 00:00:00

abstract：:The diagnosis of primary angiosarcoma of ovary is still a challenge as it has no specific clinical symptoms and is easily confused with other malignant neoplasms in morphology. Here, we described a case of primary ovarian angiosarcoma and reviewed the literature. A 47-year-old female showed a left ovary mass. Grossly,...

journal_title：Journal of ovarian research

authors： Ye H,Lin M,Li R,Qin S,Hou G,Chen H,Li X

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:The imbalance of expression of microRNA-802 may have a significant place in tumor progression. However, the bio-function of epithelial ovarian cancer cells remains unclear. Therefore, we setup this study to explore the pathogenesis of epithelial ovarian cancer based on microRNA-802. METHODS:RT-qPCR analysis...

journal_title：Journal of ovarian research

authors： Yang B,Sun L,Liang L

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:Cell lines are very useful for both clinical and basic research. The establishment of ovarian, malignant tumor cell lines with aggressive histology is especially important. We describe the establishment and characterization of a new human clear cell carcinoma cell line of the ovary. RESULTS:The cell line HC...

journal_title：Journal of ovarian research

authors： Yamada T,Hattori K,Satomi H,Okazaki T,Mori H,Hirose Y

更新日期：2016-06-04 00:00:00

abstract：BACKGROUND:Recent studies have shown that microRNAs may regulate the ABCB1 gene (ATP-binding cassette, sub-family B [MDR/TAP], member 1). Computational programs have predicted that the 3'-untranslated region (3'-UTR) of ABCB1 contains a potential miRNA-binding site for miR-186. Here, we investigated the role of miR-186...

journal_title：Journal of ovarian research

authors： Sun KX,Jiao JW,Chen S,Liu BL,Zhao Y

更新日期：2015-12-02 00:00:00

abstract：BACKGROUND:The ST6Gal-I glycosyltransferase, which adds α2-6-linked sialic acids to N-glycosylated proteins is upregulated in a wide range of malignancies including ovarian cancer. Prior studies have shown that ST6Gal-I-mediated sialylation of select surface receptors remodels intracellular signaling to impart cancer s...

journal_title：Journal of ovarian research

authors： Dorsett KA,Jones RB,Ankenbauer KE,Hjelmeland AB,Bellis SL

更新日期：2019-10-14 00:00:00

abstract：BACKGROUND:The prevalence of obesity is increasing worldwide and significantly affects fertility and reproduction in both men and women. Our recent study has shown that excess body fat accelerates ovarian follicle development and follicle loss in rats. The aim of the present study is to explore the effect of SIRT1 acti...

journal_title：Journal of ovarian research

authors： Zhou XL,Xu JJ,Ni YH,Chen XC,Zhang HX,Zhang XM,Liu WJ,Luo LL,Fu YC

更新日期：2014-10-21 00:00:00

abstract：BACKGROUND:Studies on the association between obesity and ovarian cancer survival have had conflicting results. We reviewed and quantitatively summarized the existing evidence, exploring potentially important sources of variability, such as the timing of body mass index (BMI) assessment, BMI cut points, references used...

journal_title：Journal of ovarian research

authors： Bae HS,Kim HJ,Hong JH,Lee JK,Lee NW,Song JY

更新日期：2014-04-22 00:00:00

abstract：BACKGROUND:Despite advances in surgical aggressiveness and conventional chemotherapy, ovarian cancer remains the most lethal cause of gynecologic cancer mortality; consequently there is a need for new therapeutic agents and innovative treatment paradigms for the treatment of ovarian cancer. Several studies have demonst...

journal_title：Journal of ovarian research

authors： Thomas ED,Meza-Perez S,Bevis KS,Randall TD,Gillespie GY,Langford C,Alvarez RD

更新日期：2016-10-27 00:00:00

abstract：BACKGROUND:Gonadoblastoma (GB) is a rare mixed germ cell-sex cord-stromal tumour, first described in humans, commonly found in dysgenetic gonads of intersex patients that have a Y chromosome. However, this entity in not recognized in the WHO classification of tumours of genital system of domestic animals. Herein, we de...

journal_title：Journal of ovarian research

authors： Flores AR,Lobo J,Nunes F,Rêma A,Lopes P,Carvalho L,Bartosch C,Amorim I,Gärtner F

更新日期：2019-09-23 00:00:00

abstract：BACKGROUNDS:Long non-coding RNA is a novel group of non-protein coding transcripts over 200 nt in length. Recent studies have found that they are widely involved in many pathological and physiological processes. In our previous study, we found that lnc-GULP1-2:1 was significantly down-regulated in the ovarian cortical ...

journal_title：Journal of ovarian research

authors： Yao G,Kong Y,Yang G,Kong D,Xu Y,He J,Xu Z,Bai Y,Fan H,He Q,Sun Y

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:The use of long protocol during controlled ovarian stimulation for assisted reproduction attracts high dosage of gonadotropins. High dose of gonadotropins can be detrimental to oocyte development, which affects its quality and compromises the treatment outcome. Mild stimulation protocols that attract low dos...

journal_title：Journal of ovarian research

authors： Ochin H,Ma X,Wang L,Li X,Song J,Meng Y,Shen J,Cui YG,Liu J

更新日期：2018-05-04 00:00:00

abstract：:Previously anecdotally observed rebounds in follicle growth after interruption of exogenous gonadotropins in absolute non-responders were the impetus for here reported study. In a prospective cohort study, we investigated 49 consecutive patients, absolutely unresponsive to maximal exogenous gonadotropin stimulation, f...

journal_title：Journal of ovarian research

authors： Gleicher N,Weghofer A,Darmon SK,Barad DH

更新日期：2021-01-09 00:00:00

abstract：BACKGROUND:Whether there is a mechanistic link between FOLR1 and response to cisplatin has not been extensively examined. In this study, we determine the expression of FOLR1 in ovarian cancer and examine if FOLR1 levels influence response to cisplatin. RESULTS:(1) FOLR1 protein expression was lowest in normal ovarian ...

journal_title：Journal of ovarian research

authors： Huang MJ,Zhang W,Wang Q,Yang ZJ,Liao SB,Li L

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Epithelial ovarian cancer has the highest fatality rate of all gynecologic malignancies. Although the majority of patients achieve complete clinical response after initial cytoreductive surgery and platinum-based chemotherapy, most recur and almost all will eventually acquire platinum-resistance for which tr...

journal_title：Journal of ovarian research

authors： Cohen S,Schwartz M,Dottino P,Beddoe AM

更新日期：2019-04-25 00:00:00

abstract：BACKGROUND:Mucinous carcinomas from different organs are morphologically similar and might share similarities at the molecular and biochemical levels that may illuminate their pathogenesis and influence management. The factors involved in the pathogenesis of mucinous carcinomas remain unknown; which is likely one contr...

journal_title：Journal of ovarian research

authors： Desouki MM,Franklin RB,Costello LC,Fadare O

更新日期：2015-06-17 00:00:00

abstract：UNLABELLED: BACKGROUND:Women with polycystic ovary syndrome (PCOS) have higher risk for cardiovascular disease (CVD). Heart type fatty acid binding protein (HFABP) has been found to be predictive for myocardial ischemia.Wet ested whether HFABP is the predictor for CVD in PCOS patients, who have an increased risk of ca...

journal_title：Journal of ovarian research

authors： Cakir E,Ozbek M,Sahin M,Cakal E,Gungunes A,Ginis Z,Demirci T,Delibasi T

更新日期：2012-12-18 00:00:00

abstract：BACKGROUND:Pelvic irradiation is essential for improving survival in women with pelvic malignancies despite inducing permanent ovarian damage. Ovarian transposition can be performed in premenopausal women in an attempt to preserve ovarian function. As uncertainty occurs over the proportion of women who are likely to be...

journal_title：Journal of ovarian research

authors： Gubbala K,Laios A,Gallos I,Pathiraja P,Haldar K,Ind T

更新日期：2014-06-25 00:00:00

abstract：:Infertility is a medical and social condition that affects millions of women worldwide and is today considered so far as a new disease. A considerable progress has been recently pursued in the field of the reproductive medicine and the infertility treatment may account for novel and modern procedures such as in vitro ...

journal_title：Journal of ovarian research

authors： Silvestris E,D'Oronzo S,Cafforio P,D'Amato G,Loverro G

更新日期：2015-08-07 00:00:00

abstract：OBJECTIVES:The ovarian tumor marker CA125 is expressed on human MUC16, a cell surface bound mucin that is also shed by proteolytic cleavage. Human MUC16 is overexpressed by ovarian cancer cells. MUC16 facilitates the binding of ovarian tumor cells to mesothelial cells lining the peritoneal cavity. Additionally, MUC16 a...

journal_title：Journal of ovarian research

authors： Goodell CA,Belisle JA,Gubbels JA,Migneault M,Rancourt C,Connor J,Kunnimalaiyaan M,Kravitz R,Tucker W,Zwick M,Patankar MS

更新日期：2009-06-18 00:00:00

abstract：BACKGROUND:Neovascularization is necessary for follicular growth. Vascularization is first observed in preantral follicles, and thereafter the vasculature markedly increases in follicles undergoing development. Neovascularization includes angiogenesis and vasculogenesis. Vasculogenesis is the formation of new blood ves...

journal_title：Journal of ovarian research

authors： Kizuka-Shibuya F,Tokuda N,Takagi K,Adachi Y,Lee L,Tamura I,Maekawa R,Tamura H,Suzuki T,Owada Y,Sugino N

更新日期：2014-01-21 00:00:00

abstract：OBJECTIVE:To review utilisation of elective embryo cryopreservation in the expectant management of patients at risk for developing ovarian hyperstimulation syndrome (OHSS), and report on reproductive outcome following transfer of thawed embryos. MATERIALS AND METHODS:Medical records were reviewed for patients undergoi...

journal_title：Journal of ovarian research

authors： Sills ES,McLoughlin LJ,Genton MG,Walsh DJ,Coull GD,Walsh AP

更新日期：2008-11-06 00:00:00

abstract：BACKGROUND:Low adiponectin levels in polycystic ovarian syndrome (PCOS) have been largely attributed to obesity which is common among these patients. In addition, evidence also suggests that low adiponectin in PCOS may be related to insulin resistance (IR) in these women. However, studies on the role of adiponectin in ...

journal_title：Journal of ovarian research

authors： Mirza SS,Shafique K,Shaikh AR,Khan NA,Anwar Qureshi M

更新日期：2014-02-07 00:00:00

abstract：BACKGROUND:Hyaluronic acid is a prognostic factor in ovarian cancers. It is also a component of Hyaluronic Acid-Carboxymethyl Cellulose (HA-CMC) barrier, an anti-adhesion membrane widely used during abdominal surgeries in particular for ovarian carcinosis. 70% of patients who undergo ovarian surgery will relapse due to...

journal_title：Journal of ovarian research

authors： Picaud L,Thibault B,Mery E,Ouali M,Martinez A,Delord JP,Couderc B,Ferron G

更新日期：2014-04-16 00:00:00