Lnc-GULP1-2:1 affects granulosa cell proliferation by regulating COL3A1 expression and localization.

abstract：BACKGROUND:Studies on the association between obesity and ovarian cancer survival have had conflicting results. We reviewed and quantitatively summarized the existing evidence, exploring potentially important sources of variability, such as the timing of body mass index (BMI) assessment, BMI cut points, references used...

journal_title：Journal of ovarian research

authors： Bae HS,Kim HJ,Hong JH,Lee JK,Lee NW,Song JY

更新日期：2014-04-22 00:00:00

abstract：:As the human ovarian follicle enlarges in the course of a regular cycle or following controlled ovarian stimulation, the changes in its structure reveal the oocyte environment composed of cumulus oophorus cells and the follicular fluid (FF).In contrast to the dynamic nature of cells, the fluid compartment appears as a...

journal_title：Journal of ovarian research

authors： Freitas C,Neto AC,Matos L,Silva E,Ribeiro Â,Silva-Carvalho JL,Almeida H

更新日期：2017-07-12 00:00:00

abstract：:Ovarian cystic tumors with a mural nodule are a rare entity. We report a case of a mural nodule of anaplastic spindle cell carcinoma in an ovarian mucinous cystic tumor of borderline malignancy. The patient was a 45-years-old Japanese woman who presented with an ovarian cyst. She suffered from mature cystic teratoma o...

journal_title：Journal of ovarian research

authors： Yamazaki H,Matsuzawa A,Shoda T,Iguchi H,Kyushima N

更新日期：2013-12-05 00:00:00

abstract：BACKGROUND:This study aimed to examine the performance of the four risk of malignancy index (RMI) in discriminating borderline ovarian tumors (BOTs) and benign ovarian masses in daily clinical practice. METHODS:A total of 162 women with BOTs and 379 women with benign ovarian tumors diagnosed at the Second Affiliated H...

journal_title：Journal of ovarian research

authors： Zhang S,Yu S,Hou W,Li X,Ning C,Wu Y,Zhang F,Jiao YF,Lee LTO,Sun L

更新日期：2019-09-16 00:00:00

abstract：:Mixed germ cell tumours of the ovary are malignant neoplasms of the ovary comprising of two or more types of germ cell components. Most of the malignant mixed germ cell tumours consists of dysgerminoma accompanied by endodermal sinus tumours, immature teratoma or choriocarcinoma. There are only few case reports of mix...

journal_title：Journal of ovarian research

authors： Goyal LD,Kaur S,Kawatra K

更新日期：2014-11-04 00:00:00

abstract：BACKGROUND:Cell lines are very useful for both clinical and basic research. The establishment of ovarian, malignant tumor cell lines with aggressive histology is especially important. We describe the establishment and characterization of a new human clear cell carcinoma cell line of the ovary. RESULTS:The cell line HC...

journal_title：Journal of ovarian research

authors： Yamada T,Hattori K,Satomi H,Okazaki T,Mori H,Hirose Y

更新日期：2016-06-04 00:00:00

abstract：BACKGROUND:Ovarian cancer is the second most common gynecologic malignancy. As the primary imaging modality, computed tomography (CT) can provide staging information for preoperative planning and determination of surgical resectability. As a new three-dimensional postprocessing tool for CT images, cinematic rendering (...

journal_title：Journal of ovarian research

authors： Jin YR,Yang XL,Li QQ,Yan ZL,Yang HY,Liao C

更新日期：2018-09-26 00:00:00

abstract：BACKGROUND:Whether there is a mechanistic link between FOLR1 and response to cisplatin has not been extensively examined. In this study, we determine the expression of FOLR1 in ovarian cancer and examine if FOLR1 levels influence response to cisplatin. RESULTS:(1) FOLR1 protein expression was lowest in normal ovarian ...

journal_title：Journal of ovarian research

authors： Huang MJ,Zhang W,Wang Q,Yang ZJ,Liao SB,Li L

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Resistance to apoptosis is a major problem in ovarian cancer (OC) and correlates with poor prognosis. Osteoprotegerin (OPG) is a soluble secreted factor that acts as a decoy receptor for receptor activator of NF-κB ligand (RANKL) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). OPG has be...

journal_title：Journal of ovarian research

authors： Lane D,Matte I,Laplante C,Garde-Granger P,Rancourt C,Piché A

更新日期：2013-11-23 00:00:00

abstract：BACKGROUND:Experience on sentinel node mapping in ovarian tumors is very limited. We evaluated the sentinel node concept in ovarian tumors using intra-operativeTc-99m-Phytate injection and lymphoscintigraphy imaging. METHODS:Thirty-five patients with a pelvic mass due to an ovarian pathology were included in the study...

journal_title：Journal of ovarian research

authors： Hassanzadeh M,Hosseini Farahabadi E,Yousefi Z,Kadkhodayan S,Zarifmahmoudi L,Sadeghi R

更新日期：2016-09-07 00:00:00

abstract：:The original article [1] contains errors in Fig. 3C, Results and Discussion. ...

journal_title：Journal of ovarian research

authors： Wu H,Li R,Zhang Z,Jiang H,Ma H,Yuan C,Sun C,Li Y,Kong B

更新日期：2020-03-13 00:00:00

abstract：OBJECTIVES:The ovarian tumor marker CA125 is expressed on human MUC16, a cell surface bound mucin that is also shed by proteolytic cleavage. Human MUC16 is overexpressed by ovarian cancer cells. MUC16 facilitates the binding of ovarian tumor cells to mesothelial cells lining the peritoneal cavity. Additionally, MUC16 a...

journal_title：Journal of ovarian research

authors： Goodell CA,Belisle JA,Gubbels JA,Migneault M,Rancourt C,Connor J,Kunnimalaiyaan M,Kravitz R,Tucker W,Zwick M,Patankar MS

更新日期：2009-06-18 00:00:00

abstract：:High-Grade Serous Ovarian Carcinoma (HGSOC) is the predominant histotype of epithelial ovarian cancer (EOC), characterized by advanced stage at diagnosis, frequent TP53 mutation, rapid progression, and high responsiveness to platinum-based-chemotherapy. To date, standard first-line-chemotherapy in advanced EOC include...

journal_title：Journal of ovarian research

authors： Mignogna C,Staropoli N,Botta C,De Marco C,Rizzuto A,Morelli M,Di Cello A,Franco R,Camastra C,Presta I,Malara N,Salvino A,Tassone P,Tagliaferri P,Barni T,Donato G,Di Vito A

更新日期：2016-05-21 00:00:00

abstract：BACKGROUND:Ovarian cancer is the leading cause of gynecological cancer-related mortality. The novel oncogene S100A10 has been reported to be involved in cancer cell proliferation, invasion and metastasis. The role of S100A10 in ovarian cancer has not been well studied and the effect of S100A10 on chemotherapy remains u...

journal_title：Journal of ovarian research

authors： Wang L,Yan W,Li X,Liu Z,Tian T,Chen T,Zou L,Cui Z

更新日期：2019-11-18 00:00:00

abstract：:Infertility is a medical and social condition that affects millions of women worldwide and is today considered so far as a new disease. A considerable progress has been recently pursued in the field of the reproductive medicine and the infertility treatment may account for novel and modern procedures such as in vitro ...

journal_title：Journal of ovarian research

authors： Silvestris E,D'Oronzo S,Cafforio P,D'Amato G,Loverro G

更新日期：2015-08-07 00:00:00

abstract：BACKGROUND:Ovarian cancer (OC) was the primary malignant gynecological cancer and SNARE protein is closely related with tumor progression. Here, we identified SNAP23, a member of SNARE complex, as a potential oncogene in OC. METHODS:We determined the expression of SNAP23 in OC tissues and explored the clinical signifi...

journal_title：Journal of ovarian research

authors： Sun Q,Huang X,Zhang Q,Qu J,Shen Y,Wang X,Sun H,Wang J,Xu L,Chen X,Ren B

更新日期：2016-11-17 00:00:00

abstract：OBJECTIVES:Endometrioid carcinoma of the ovary is one of the most types of epithelial ovarian cancer associated to endometrioisis. Endometrioid tumors as well as endometriotic implants are characterized by the presence of epithelial cells, stromal cells, or a combination of booth, that resemble the endometrial cells, s...

journal_title：Journal of ovarian research

authors： Keita M,Bessette P,Pelmus M,Ainmelk Y,Aris A

更新日期：2010-01-28 00:00:00

abstract：BACKGROUND:The prevalence of obesity is increasing worldwide and significantly affects fertility and reproduction in both men and women. Our recent study has shown that excess body fat accelerates ovarian follicle development and follicle loss in rats. The aim of the present study is to explore the effect of SIRT1 acti...

journal_title：Journal of ovarian research

authors： Zhou XL,Xu JJ,Ni YH,Chen XC,Zhang HX,Zhang XM,Liu WJ,Luo LL,Fu YC

更新日期：2014-10-21 00:00:00

abstract：BACKGROUND:Recent studies have shown that microRNAs may regulate the ABCB1 gene (ATP-binding cassette, sub-family B [MDR/TAP], member 1). Computational programs have predicted that the 3'-untranslated region (3'-UTR) of ABCB1 contains a potential miRNA-binding site for miR-186. Here, we investigated the role of miR-186...

journal_title：Journal of ovarian research

authors： Sun KX,Jiao JW,Chen S,Liu BL,Zhao Y

更新日期：2015-12-02 00:00:00

abstract：BACKGROUND:Epithelial ovarian cancer has the highest fatality rate of all gynecologic malignancies. Although the majority of patients achieve complete clinical response after initial cytoreductive surgery and platinum-based chemotherapy, most recur and almost all will eventually acquire platinum-resistance for which tr...

journal_title：Journal of ovarian research

authors： Cohen S,Schwartz M,Dottino P,Beddoe AM

更新日期：2019-04-25 00:00:00

abstract：BACKGROUND:The use of long protocol during controlled ovarian stimulation for assisted reproduction attracts high dosage of gonadotropins. High dose of gonadotropins can be detrimental to oocyte development, which affects its quality and compromises the treatment outcome. Mild stimulation protocols that attract low dos...

journal_title：Journal of ovarian research

authors： Ochin H,Ma X,Wang L,Li X,Song J,Meng Y,Shen J,Cui YG,Liu J

更新日期：2018-05-04 00:00:00

abstract：BACKGROUND:In recent years the question of the lack of transparency in clinical research has been debated by clinicians, researchers, citizens and their representatives, authors and publishers. This is particularly important for infrequent cancers such as ovarian cancer, where treatment still gives disappointing result...

journal_title：Journal of ovarian research

authors： Roberto A,Radrezza S,Mosconi P

更新日期：2018-04-10 00:00:00

abstract：BACKGROUND:Polycystic Ovary Syndrome (PCOS) is a widespread reproductive disorder characterized by a disruption of follicular growth and anovulatory infertility. In women with PCOS, follicular growth and ovulation can be induced by subcutaneous injections of low doses of follicle stimulating hormone (FSH). The aim of t...

journal_title：Journal of ovarian research

authors： Tessaro I,Modina SC,Franciosi F,Sivelli G,Terzaghi L,Lodde V,Luciano AM

更新日期：2015-10-06 00:00:00

abstract：BACKGROUND:Ovarian cancer (OVC) is the deadliest of all gynecologic cancers, primarily as a consequence of asymptomatic progression. The complex nature of OVC creates challenges for early detection, and there is a lack of specific and sensitive biomarkers suitable for screening and detecting early stage OVC. METHODS:P...

journal_title：Journal of ovarian research

authors： Tamir A,Gangadharan A,Balwani S,Tanaka T,Patel U,Hassan A,Benke S,Agas A,D'Agostino J,Shin D,Yoon S,Goy A,Pecora A,Suh KS

更新日期：2016-03-31 00:00:00

abstract：BACKGROUND:Metformin decreases polycystic ovary syndrome (PCOS) symptoms, induces ovulation, and may improve developmental competence of in vitro oocyte maturation. This study was designed to define the effects of metformin on the characteristics of in vitro oocyte maturation in estradiol valerate (EV) PCOS-induced rat...

journal_title：Journal of ovarian research

authors： Mesbah F,Moslem M,Vojdani Z,Mirkhani H

更新日期：2015-11-14 00:00:00

abstract：BACKGROUND:Epithelial ovarian cancer (EOC) is still a major gynecologic problem with poor 5 year survival rate due to distance metastases, despite routine surgery and chemotherapy. The precise underlying molecular mechanisms that trigger EOC migration and invasion are unclear. Recent studies suggest that the expression...

journal_title：Journal of ovarian research

authors： Zhang H,Wang Q,Zhao Q,Di W

更新日期：2013-11-26 00:00:00

abstract：BACKGROUND:Highly Individualized Egg Retrieval (HIER), defined as age-specific early oocyte retrieval (ER), has been demonstrated to avoid premature luteinization in women ≥43. We here investigated whether HIER also applies to younger women with premature ovarian aging (POA), and what best lead follicle size should be ...

journal_title：Journal of ovarian research

authors： Wu YG,Barad DH,Kushnir VA,Wang Q,Zhang L,Darmon SK,Albertini DF,Gleicher N

更新日期：2018-03-16 00:00:00

abstract：BACKGROUND:Although agonistic autoantibodies against type-1 angiotensin-II receptor (AT1-AA) are frequently detected in women with preeclampsia, the clinical significance of AT1-AA in association with epithelial ovarian cancer (EOC) has not been identified. METHODS:In an attempt to clarify this issue, we measured seru...

journal_title：Journal of ovarian research

authors： Song L,Zhang SL,Bai KH,Yang J,Xiong HY,Li X,Liu T,Liu HR

更新日期：2013-04-05 00:00:00

abstract：:The diagnosis of primary angiosarcoma of ovary is still a challenge as it has no specific clinical symptoms and is easily confused with other malignant neoplasms in morphology. Here, we described a case of primary ovarian angiosarcoma and reviewed the literature. A 47-year-old female showed a left ovary mass. Grossly,...

journal_title：Journal of ovarian research

authors： Ye H,Lin M,Li R,Qin S,Hou G,Chen H,Li X

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:The mechanisms regulating the function and regression of the corpus luteum (CL) have not yet been elucidated in detail. The regressed CL of cows was previously reported to be filled with unusual vessels like arteriovenous anastomosis (AVA); however how these vessels are being established during luteolysis re...

journal_title：Journal of ovarian research

authors： Nio-Kobayashi J,Miyazaki K,Hashiba K,Okuda K,Iwanaga T

更新日期：2016-10-19 00:00:00