Sheehan's syndrome: differential diagnosis in the acute phase.

abstract：:In 76 consecutive patients who had received diuretics for 1-17 years for arterial hypertension or congestive heart failure, muscle concentrations of magnesium, potassium, and sodium-potassium pumps were significantly reduced compared to 31 age- and sex-matched controls. Thirty-six patients with muscle magnesium and/or...

journal_title：Journal of internal medicine

authors： Dørup I,Skajaa K,Thybo NK

更新日期：1993-02-01 00:00:00

abstract：:Two hundred consecutive patients with femoral neck fractures (FNF) and 200 controls matched by age, sex, nursing home residency and number of admissions within the last 2 years, were interviewed about recent drug use. The matching criteria were chosen to achieve case and control groups that were comparable with regard...

journal_title：Journal of internal medicine

authors： Jensen J,Nielsen LH,Lyhne N,Hallas J,Brøsen K,Gram LF

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:To examine whether intermittent oral 1 alpha(OH)D3 treatment of patients on haemodialysis with secondary hyperparathyroidism (HPT) was able to maintain the marked suppression of PTH, which previously had been induced by an intermittent intravenous administration of 1 alpha(OH)D3. Simultaneously, the effect o...

journal_title：Journal of internal medicine

authors： Brandi L,Daugaard H,Egsmose C,Tvedegaard E,Kjaerulff Nielsen P,Olgaard K

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVES:To evaluate the concentrations of magnesium (Mg), potassium (K) and sodium,potassium pumps (Na,K pumps) in skeletal muscle in patients with chronic obstructive lung disease (COLD) treated with or without diuretics. DESIGN:An open cross-sectional study. SETTING:COLD patients admitted to the Medical Departme...

journal_title：Journal of internal medicine

authors： Ravn HB,Dørup I

更新日期：1997-01-01 00:00:00

abstract：:This review describes global patterns of tobacco use and the mechanisms by which tobacco use is involved in carcinogenesis. A second part will discuss the association between tobacco use and risk of specific cancer types. Tobacco use has traditionally been a practice of high-income countries, but it has recently been ...

journal_title：Journal of internal medicine

authors： Kuper H,Adami HO,Boffetta P

更新日期：2002-06-01 00:00:00

abstract：:The introduction of biologic therapies heralded a new era in the treatment for chronic inflammatory autoimmune diseases of which rheumatoid arthritis is one of the most prevalent. From a scientific point of view, these therapies demonstrated that the targeting of individual cytokines or cell-surface markers is a very ...

journal_title：Journal of internal medicine

authors： Chatzidionysiou K,van Vollenhoven RF

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:To determine whether a first myocardial infarction leads to increased plasma homocysteine concentrations and whether the association between homocysteine and myocardial infarction was greater at follow-up compared with baseline. DESIGN:A population-based, prospective, nested case-referent study. SETTING:Sc...

journal_title：Journal of internal medicine

authors： Hultdin J,Thøgersen AM,Jansson JH,Nilsson TK,Weinehall L,Hallmans G

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To study the association between postural hypotension and (i) electrolyte levels and (ii) neurohumoral factors in elderly hypertensive patients using diuretics. DESIGN:Cross-sectional study of patients and controls. SETTING:The subjects were gathered from senior citizen clubs or they were referred to the st...

journal_title：Journal of internal medicine

authors： Luutonen S,Neuvonen P,Ruskoaho H,Räihä I,Rajala T,Antila K,Sourander L

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVES:The angiotensinogen (AGT) gene has been implicated as a candidate gene of high blood pressure. However, because the variants of the AGT gene are point mutations, it is difficult to detect them in large scale population studies. The aims of this study were to develop a rapid screening method for the point mut...

journal_title：Journal of internal medicine

authors： Morise T,Takeuchi Y,Takeda R

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVES:To evaluate the prognostic value of exercise testing performed soon after acute myocardial infarction (AMI) in patients treated with thrombolytic therapy. DESIGN:A 1-year prospective follow-up of 185 subjects treated with thrombolytic therapy who survived AMI, and who performed exercise testing 3 weeks afte...

journal_title：Journal of internal medicine

authors： Abboud L,Hir J,Eisen I,Markiewicz W

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVES:Microbial translocation and chronic immune activation were previously shown to be associated with impairment of T cell functions and disease progression during infection with human immunodeficiency virus type-1 (HIV-1); however, their impact on B cell function and number remains unknown. By measuring markers...

journal_title：Journal of internal medicine

authors： Ruffin N,Lantto R,Pensieroso S,Sammicheli S,Hejdeman B,Rethi B,Chiodi F

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:To examine the occurrence over time of the metabolic syndrome (MetS) according to different definitions and the relation to change during follow-up in carotid artery intima-media thickness (IMT), measured by ultrasound. DESIGN:A cohort of 316, originally 58-year-old men, initially free of diabetes and cardi...

journal_title：Journal of internal medicine

authors： Wallenfeldt K,Hulthe J,Fagerberg B

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To investigate influence of whole-body cooling on cyclic GMP (cGMP) in women with Raynaud's phenomenon and in healthy women. DESIGN:The study was performed as an open, parallel-group comparison between women with Raynaud's phenomenon and healthy women during the winter month of February. SETTING:The municip...

journal_title：Journal of internal medicine

authors： Leppert J,Ringqvist A,Ahlner J,Myrdal U,Sørensen S,Ringqvist I

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:The mechanisms explaining morphological electrocardiogram (ECG) changes and increased troponin T (TnT) in acute stroke are unclear. The aims of the present study were to assess the prevalence of ECG and TnT changes in acute ischaemic stroke, to investigate whether ischaemic-like ECG changes correlate to a ri...

journal_title：Journal of internal medicine

authors： Fure B,Bruun Wyller T,Thommessen B

更新日期：2006-06-01 00:00:00

abstract：:Mucosal surfaces of the body serve as the major portal of entry for human immunodeficiency virus (HIV). These tissues also house a majority of the body's lymphocytes, including the CD4(+) T cells that are the major cellular target for HIV infection. Mucosal surfaces are defended by innate and adaptive immune mechanism...

journal_title：Journal of internal medicine

authors： Shacklett BL,Critchfield JW,Ferre AL,Hayes TL

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Statins reduce low-density lipoprotein cholesterol (LDL-C) and can raise high-density lipoprotein cholesterol (HDL-C). HDL-bound paraoxonase-1 (PON1) is associated with variations in plasma HDL-C, and may, therefore, contribute to changes of HDL-C during statin therapy. DESIGN:The effects of baseline PON1 s...

journal_title：Journal of internal medicine

authors： Himbergen TM,van Tits LJ,Voorbij HA,de Graaf J,Stalenhoef AF,Roest M

更新日期：2005-11-01 00:00:00

abstract：:Seventeen patients with mild to moderate hypertension, as indicated by a diastolic blood pressure (DPB) of 95-115 mmHg (WHO I), were treated in a randomized, double-blind, parallel study, with either 5 mg of fosinopril, a new phosphinic acid-containing angiotensin converting enzyme (ACE) inhibitor, or 25 mg of hydroch...

journal_title：Journal of internal medicine

authors： Forslund T,Franzén P,Backman R

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:We evaluated the hypothesis that higher levels of total daily physical activity can eliminate the increased mortality rate associated with overweight and obesity. DESIGN:Population-based prospective cohort study. SETTING:Central Sweden. SUBJECTS:A total of 37,633 men at baseline 45-79 years of age and free...

journal_title：Journal of internal medicine

authors： Orsini N,Bellocco R,Bottai M,Pagano M,Michaelsson K,Wolk A

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between autoimmunity and extranodal lymphocytic infiltrates in different lymphoproliferative disorders with immunoglobulin alterations. SUBJECTS AND DESIGN:A clinical review combined with a retrospective cohort study of 380 patients, 28 with monoclonal gammopathy of undetermined s...

journal_title：Journal of internal medicine

authors： Jønsson V,Wiik A,Hou-Jensen K,Christiansen M,Ryder LP,Madsen HO,Geisler C,Hansen MM,Thomsen K,Vorstrup S,Svejgaard A

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVES:We evaluated mortality from cardiovascular disease (CVD), coronary heart disease (CHD) and all causes in relation to use of any hormone therapy (HT) and HT with oestradiol and norethisterone or levonorgestrel. DESIGN:Population-based cohort study. SETTING AND SUBJECTS:Women in three Norwegian counties were...

journal_title：Journal of internal medicine

authors： Graff-Iversen S,Hammar N,Thelle DS,Tonstad S

更新日期：2004-11-01 00:00:00

abstract：:The acquired immunodeficiency syndrome (AIDS) has been associated with abnormalities of adrenocortical function, and hypoaldosteronism due to hyporeninaemic hypoaldosteronism (HHA). We here report the case of a woman with AIDS associated with orthostatic hypotension, persistent hyponatraemia and hyperkalaemia, in whom...

journal_title：Journal of internal medicine

authors： Cobbs R,Pepper GM,Torres JG,Gruenspan HL

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVES:To investigate the risk of ipsilateral versus contralateral recurrent deep vein thrombosis in the leg. DESIGN:An open prospective long term follow-up multicentre trial. Patients were followed by frequent outpatient visits at each centre during the first 12 months after inclusion and thereafter annually. SE...

journal_title：Journal of internal medicine

authors： Lindmarker P,Schulman S

更新日期：2000-05-01 00:00:00

abstract：:A 52-year-old white male subject with typical clinical and laboratory findings of Waldenström's macroglobulinaemia is described. Two paraprotein peaks of IgM lambda class, with different physical and chemical properties and different amino acid compositions, in both heavy and light chains, were found in the patient's ...

journal_title：Journal of internal medicine

authors： Ruiz-Palomo F,Revilla Y,Gonzales Porque P,Serrano Rios M

更新日期：1991-01-01 00:00:00

abstract：:To determine the effect of prednisolone on severe hypercalcaemia in women with metastatic breast cancer, 30 patients with serum ionized calcium above 1.60 mmol l-1 (reference range 1.15-1.35 mmol l-1) entered a randomized trial. Performance status before entry to the trial and survival time after hypercalcaemia were a...

journal_title：Journal of internal medicine

authors： Kristensen B,Ejlertsen B,Holmegaard SN,Krarup-Hansen A,Transbøl I,Mouridsen H

更新日期：1992-09-01 00:00:00

abstract：:A 61-year-old female patient, treated for hyperthyroidism with thiamazole, developed a severe maturation arrest in the granulocytic lineage and a total agranulocytosis. Subcutaneous GM-CSF was started immediately and given for 6 days. Bone marrow samples were taken before GM-CSF therapy and on days 3 and 8. An increas...

journal_title：Journal of internal medicine

authors： Björkholm M,Pisa P,Arver S,Beran M

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Metabolomics is a versatile unbiased method to search for biomarkers of human disease. In particular, one approach in cancer therapy is to promote apoptosis in tumour cells; this could be improved with specific biomarkers of apoptosis for monitoring treatment. We recently observed specific metabolic patterns...

journal_title：Journal of internal medicine

authors： Halama A,Riesen N,Möller G,Hrabě de Angelis M,Adamski J

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVES:Sunlight exposure of the skin is known to be the most important source of vitamin D. The aims of this study were: (i) to estimate vitamin D status amongst sunlight-deprived individuals (veiled Arab women, veiled ethnic Danish Moslem women and Danish controls); and (ii) through food intake analysis to estimat...

journal_title：Journal of internal medicine

authors： Glerup H,Mikkelsen K,Poulsen L,Hass E,Overbeck S,Thomsen J,Charles P,Eriksen EF

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:To investigate the adjusted relative risk of cardiovascular disease (CVD) events in offspring of parents with cardiovascular mortality before 75 years. SETTING:The city of Malmö, Sweden. DESIGN:A follow-up study based on register linkage analyses. SUBJECTS AND METHODS:In the Malmö Preventive Project (MPP),...

journal_title：Journal of internal medicine

authors： Nilsson PM,Nilsson JA,Berglund G

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:Apolipoprotein A-V (apoAV) contributes to the regulation of triglyceride metabolism, which plays a role in the pathogenesis of atherosclerotic diseases. We therefore ascertained determinants of hepatic APOA5 transcript and apoAV plasma levels in humans. DESIGN:We determined influences of anthropometric varia...

journal_title：Journal of internal medicine

authors： Hahne P,Krempler F,Schaap FG,Soyal SM,Höffinger H,Miller K,Oberkofler H,Strobl W,Patsch W

更新日期：2008-11-01 00:00:00

abstract：:A 64-year-old lady with a personal and family history of autoimmune disease developed chronic myelomonocytic leukaemia and multiple myeloma simultaneously. Her sister died of acute myelomonocytic leukaemia, but showed no evidence of autoimmune disease. It is possible that chronic immunological stimulation, perhaps by ...

journal_title：Journal of internal medicine

authors： Habashi HM,Sharp RA,Pippard MJ

更新日期：1991-10-01 00:00:00