Combined effects of obesity and physical activity in predicting mortality among men.

abstract：:Forty-one patients with hyperprolactinaemia and suspected prolactinomas were studied. Growth hormone (GH) and thyrotropin (TSH) secretory patterns after thyrotropin releasing hormone (TRH) were affected in the majority of patients. The disturbances were observed regardless of tumour size as indicated by the radiologic...

journal_title：Journal of internal medicine

authors： Brismar K,Hulting AL,Werner S

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVES:To investigate the concordance of anti-hepatitis C virus (anti-HCV) reactivity by a second-generation enzyme immunoassay (EIA-2) and by a four-antigen recombinant immunoblot assay (4-RIBA) in homosexual men, in comparison with that found in other sexually active groups and blood donors. DESIGN:Prospective s...

journal_title：Journal of internal medicine

authors： Andreu J,Abad MA,Sanchez-Quijano A,Torronteras R,Luque F,Garcia de las Heras J,Soto B,Pineda JA,Leal M,Lissen E

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVES:We evaluated mortality from cardiovascular disease (CVD), coronary heart disease (CHD) and all causes in relation to use of any hormone therapy (HT) and HT with oestradiol and norethisterone or levonorgestrel. DESIGN:Population-based cohort study. SETTING AND SUBJECTS:Women in three Norwegian counties were...

journal_title：Journal of internal medicine

authors： Graff-Iversen S,Hammar N,Thelle DS,Tonstad S

更新日期：2004-11-01 00:00:00

abstract：:We report two cases of fulminant hepatic failure in HIV-1-infected patients treated with didanosine (ddI). Clinical manifestations including vomiting, diarrhoea and dyspnoea were identical in both cases. Biological data mainly revealed hepatic failure and lactic acidosis. Histological examination of liver biopsies sho...

journal_title：Journal of internal medicine

authors： Bissuel F,Bruneel F,Habersetzer F,Chassard D,Cotte L,Chevallier M,Bernuau J,Lucet JC,Trepo C

更新日期：1994-04-01 00:00:00

abstract：:Infection of mural thrombus over an area of old myocardial infarct was found in an elderly woman with cholangitis. This case is unique since cholangitis was thought to be the cause of septicaemia and ventricular aneurysm was not present. ...

journal_title：Journal of internal medicine

authors： Cheung A,Choi A

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVES:To determine whether mutations in APOA1 affect levels of high-density lipoprotein (HDL) cholesterol and to predict risk of ischaemic heart disease (IHD) and total mortality in the general population. BACKGROUND:Epidemiologically, risk of IHD is inversely related to HDL cholesterol levels. Mutations in apoli...

journal_title：Journal of internal medicine

authors： Haase CL,Frikke-Schmidt R,Nordestgaard BG,Kateifides AK,Kardassis D,Nielsen LB,Andersen CB,Køber L,Johnsen AH,Grande P,Zannis VI,Tybjaerg-Hansen A

更新日期：2011-08-01 00:00:00

abstract：:Calcium is important for bone health. It has been customary to focus on dietary calcium intake, but of central importance for the body needs in the individual patient is the actual calcium absorption. This absorption consists of an active vitamin D-mediated component and a passive diffusional component. A number of di...

journal_title：Journal of internal medicine

authors： Charles P

更新日期：1992-02-01 00:00:00

abstract：OBJECTIVES:There is uncertainty amongst clinicians about the definitions of cobalamin and folate deficiency and therefore about the indications for treatment. In this report we present the results of systematic cobalamin and folic acid treatment based upon serum cobalamin, total homocysteine (tHcy) and methylmalonic ac...

journal_title：Journal of internal medicine

authors： Björkegren K,Svärdsudd K

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Hypovitaminosis D, a condition that is highly prevalent in older adults aged 65 years and above, is associated with brain changes and dementia. Given the rapidly accumulating and complex contribution of the literature in the field of vitamin D and cognition, clear guidance is needed for researchers and clini...

journal_title：Journal of internal medicine

authors： Annweiler C,Dursun E,Féron F,Gezen-Ak D,Kalueff AV,Littlejohns T,Llewellyn DJ,Millet P,Scott T,Tucker KL,Yilmazer S,Beauchet O

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:To determine whether furosemide treatment in congestive heart failure (CHF) patients is associated with thiamine deficiency. DESIGN:Patients without heart failure and without diuretic treatment were included to compare with patients with CHF belonging to New York Heart Association (NYHA) functional class II...

journal_title：Journal of internal medicine

authors： Yue QY,Beermann B,Lindström B,Nyquist O

更新日期：1997-12-01 00:00:00

abstract：:Studies of zinc status in insulin-dependent diabetes mellitus (IDDM) have shown contradictory results. Zinc is essential for many enzymes involved in the human metabolism and may play a role in the biosynthesis and storage of insulin in the B-cell. We therefore prospectively followed 26 patients (14 males and 12 femal...

journal_title：Journal of internal medicine

authors： Melchior T,Simonsen KW,Johannessen AC,Binder C

更新日期：1989-07-01 00:00:00

abstract：:A young, apparently healthy, soldier developed acute muscle weakness and rhabdomyolysis following prolonged exercise. The resultant myoglobinuria caused severe acute renal failure. Further investigation revealed the presence of carnitine palmitoyltransferase deficiency as the cause of the rhabdomyolysis. Renal functio...

journal_title：Journal of internal medicine

authors： Berkman N,Meirow D,Katzir Z,Bar-On H

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Studies have shown that lipoprotein(a) [Lp(a)], an important carrier of oxidized phospholipids, is causally related to calcific aortic valve stenosis (CAVS). Recently, we found that Lp(a) mediates the development of CAVS through autotaxin (ATX). OBJECTIVE:To determine the predictive value of circulating ATX...

journal_title：Journal of internal medicine

authors： Nsaibia MJ,Mahmut A,Boulanger MC,Arsenault BJ,Bouchareb R,Simard S,Witztum JL,Clavel MA,Pibarot P,Bossé Y,Tsimikas S,Mathieu P

更新日期：2016-11-01 00:00:00

abstract：:This review focuses on the determinants of longevity in the industrialized world, with emphasis on results from recently established data bases. Strong evidence is now available that demonstrates that in developed countries the maximum lifespan as well as the mean lifespan have increased substantially over the past ce...

journal_title：Journal of internal medicine

authors： Christensen K,Vaupel JW

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Bradykinin-mediated angioedema (AE) is a complication associated with thrombolysis for acute ischemic stroke. Risk factors are unknown and management is discussed. OBJECTIVES:To clarify risk factors associated with bradykinin-mediated AE after thrombolysis for acute ischemic stroke. METHODS:In a case-contr...

journal_title：Journal of internal medicine

authors： Vigneron C,Lécluse A,Ronzière T,Bouillet L,Boccon-Gibod I,Gayet S,Doche E,Smadja D,Di Legge S,Dumont F,Gaudron M,Ion I,Marcel S,Sévin M,Vlaicu MB,Launay D,Arnaud I,Girard-Madoux P,Héroum C,Lefèvre S,Marc G,Obadi

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Although numerous multicentre studies have estimated the association between ozone exposure and mortality, there are currently no nationally representative multicentre studies of the ozone-mortality relationship in China. OBJECTIVE:To investigate the effect on total (nonaccidental) and cause-specific mortal...

journal_title：Journal of internal medicine

authors： Sun Q,Wang W,Chen C,Ban J,Xu D,Zhu P,He MZ,Li T

更新日期：2018-05-01 00:00:00

abstract：:The B lymphocyte-associated antigen CD20 is becoming an important immunotherapy target for autoimmune diseases, although its biological function has not been defined. Besides rheumatoid arthritis, growing experience with B cell-depleting therapy indicates that it may be effective in Sjögren's syndrome, dermatomyositis...

journal_title：Journal of internal medicine

authors： Perosa F,Prete M,Racanelli V,Dammacco F

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Heart failure is characterized by chronically increased adenosine levels, which are thought to express a protective anti-heart failure activation of the adenosinergic system. The aim of the study was to assess whether the activation of adenosinergic system in idiopathic dilated cardiomyopathy (IDC) can be mi...

journal_title：Journal of internal medicine

authors： Laghi-Pasini F,Guideri F,Petersen C,Lazzerini PE,Sicari R,Capecchi PL,Picano E

更新日期：2003-12-01 00:00:00

abstract：:Pathological deviations in bodyweight is a major increasing health problem in industrialized societies. It is currently unclear what genetic mechanisms are involved in the long-term control of human body-weight and to what extent these genes are involved in pathological deviations of bodyweight control such as anorexi...

journal_title：Journal of internal medicine

authors： Schalling M,Johansen J,Nordfors L,Lönnqvist F

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVES:To examine to what extent traditional biomedical risk factors and social factors can predict, separately or jointly, first-ever stroke event, and to explore to what extent other risk factors might add to hypertension/elevated blood pressure as a stroke risk factor. DESIGN:An incident case-referent study. S...

journal_title：Journal of internal medicine

authors： Ohgren B,Weinehall L,Stegmayr B,Boman K,Hallmans G,Wall S

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVES:The magnitude of cardiovascular risk associated with psoriasis has been debated and the prognostic impact of psoriasis following myocardial infarction (MI) is unknown. Therefore, we investigated the risk of mortality and adverse cardiovascular events in patients with psoriasis following first-time MI. DESIG...

journal_title：Journal of internal medicine

authors： Ahlehoff O,Gislason GH,Lindhardsen J,Olesen JB,Charlot M,Skov L,Torp-Pedersen C,Hansen PR

更新日期：2011-09-01 00:00:00

abstract：:Hypertriglyceridaemia, as defined by fasting triglyceride levels of greater than 2.8 mmol l-1, is a prevalent dyslipoproteinaemia in our population. The underlying pathophysiological mechanisms that result in elevations of plasma triglycerides are heterogeneous and, in most cases, incompletely understood. However, in ...

journal_title：Journal of internal medicine

authors： Fojo SS,Brewer HB

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVES:To study serum homocysteine concentration for its prediction of major coronary heart disease events amongst women. DESIGN:A case-control study nested within a follow-up study. Subjects. A total of 74 and 75 major coronary events (coronary deaths or nonfatal myocardial infarction) which occurred in women wit...

journal_title：Journal of internal medicine

authors： Knekt P,Alfthan G,Aromaa A,Heliövaara M,Marniemi J,Rissanen H,Reunanen A

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:We estimated the prevalence, incidence and risk factors of left ventricular hypertrophy (LVH) in a prospective cohort study of 26 489 participants. MATERIAL AND METHODS:The LVH was defined as Minnesota Code 310 on electrocardiogram (ECG). Everyone with this code at first visit was defined as a prevalence cas...

journal_title：Journal of internal medicine

authors： Thrainsdottir IS,Hardarson T,Thorgeirsson G,Sigvaldason H,Sigfusson N

更新日期：2003-04-01 00:00:00

abstract：:Seventeen patients with mild to moderate hypertension, as indicated by a diastolic blood pressure (DPB) of 95-115 mmHg (WHO I), were treated in a randomized, double-blind, parallel study, with either 5 mg of fosinopril, a new phosphinic acid-containing angiotensin converting enzyme (ACE) inhibitor, or 25 mg of hydroch...

journal_title：Journal of internal medicine

authors： Forslund T,Franzén P,Backman R

更新日期：1991-12-01 00:00:00

abstract：:As our understanding of the molecular mechanisms governing natural killer (NK) cell activity increases, their potential in cancer immunotherapy is growing increasingly prominent. This review analyses the currently available preclinical and clinical data regarding NK cell-based immunotherapeutic approaches in cancer st...

journal_title：Journal of internal medicine

authors： Sutlu T,Alici E

更新日期：2009-08-01 00:00:00

abstract：:A 42-year-old man presented with a mediastinal tumour. On histological examination, tuberculosis was evoked, but no definitive conclusion could be drawn. The patient thereafter developed throat ulcerations and rapidly progressing renal insufficiency due to necrotizing glomerulonephritis. After reviewing the histologic...

journal_title：Journal of internal medicine

authors： Boudes P

更新日期：1990-03-01 00:00:00

abstract：:In order to evaluate the effects of one-year antihypertensive treatment on plasma lipids and lipoproteins, 65 patients whose diastolic blood pressure was in the range 95-120 mmHg were randomly allocated to groups that received either hydrochlorothiazide or metoprolol, or both drugs when the response to one of them was...

journal_title：Journal of internal medicine

authors： Monmany J,Domingo P,Gomez JA,Sanz F,Roca-Cusachs A,Nolla J,Jane F

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:Apolipoprotein A-V (apoAV) contributes to the regulation of triglyceride metabolism, which plays a role in the pathogenesis of atherosclerotic diseases. We therefore ascertained determinants of hepatic APOA5 transcript and apoAV plasma levels in humans. DESIGN:We determined influences of anthropometric varia...

journal_title：Journal of internal medicine

authors： Hahne P,Krempler F,Schaap FG,Soyal SM,Höffinger H,Miller K,Oberkofler H,Strobl W,Patsch W

更新日期：2008-11-01 00:00:00

abstract：:Sepsis is a major clinical problem in intensive care. The mortality in septic shock is high, and predominantly due to cardiovascular collapse and multiple organ dysfunction. In sepsis high levels of circulating hyaluronan have been found, correlating to disease severity and prognosis. The reason behind the increased l...

journal_title：Journal of internal medicine

authors： Berg S

更新日期：1997-07-01 00:00:00