Effects of long-term treatment with metoprolol and hydrochlorothiazide on plasma lipids and lipoproteins.

abstract：:Two hundred consecutive patients with femoral neck fractures (FNF) and 200 controls matched by age, sex, nursing home residency and number of admissions within the last 2 years, were interviewed about recent drug use. The matching criteria were chosen to achieve case and control groups that were comparable with regard...

journal_title：Journal of internal medicine

authors： Jensen J,Nielsen LH,Lyhne N,Hallas J,Brøsen K,Gram LF

更新日期：1991-01-01 00:00:00

abstract：:Personalized medicine involves the selection of the safest and most effective pharmacological treatment based on the molecular characteristics of the patient. In the case of anticancer drugs, tumour cell alterations can have a great impact on drug activity and, in fact, most biomarkers predicting response originate fr...

journal_title：Journal of internal medicine

authors： Rodríguez-Antona C,Taron M

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Hypovitaminosis D, a condition that is highly prevalent in older adults aged 65 years and above, is associated with brain changes and dementia. Given the rapidly accumulating and complex contribution of the literature in the field of vitamin D and cognition, clear guidance is needed for researchers and clini...

journal_title：Journal of internal medicine

authors： Annweiler C,Dursun E,Féron F,Gezen-Ak D,Kalueff AV,Littlejohns T,Llewellyn DJ,Millet P,Scott T,Tucker KL,Yilmazer S,Beauchet O

更新日期：2015-01-01 00:00:00

abstract：:Somatostatin receptors are expressed on the majority of neuroendocrine tumours. The presence of these receptors is clinically useful. First, long-term treatment with somatostatin analogues controls hormonal hypersecretion, which controls flushing attacks, watery diarrhoea, hypoglycaemia and electrolyte disorders in pa...

journal_title：Journal of internal medicine

authors： Lamberts SW,Hofland LJ,Lely AJ,de Herder WW

更新日期：1998-06-01 00:00:00

abstract：:The association between dental infections and cerebral infarction was investigated in a case-control study involving 40 patients with ischaemic cerebral infarction under the age of 50, and 40 randomly selected community controls matched for sex and age. Poor oral health, as assessed by two indices measuring the severi...

journal_title：Journal of internal medicine

authors： Syrjänen J,Peltola J,Valtonen V,Iivanainen M,Kaste M,Huttunen JK

更新日期：1989-03-01 00:00:00

abstract：:An inverse relationship between the concentration of high-density lipoprotein (HDL) cholesterol and the risk of developing cardiovascular is well established. There are several documented functions of HDLs that may contribute to a protective role of these lipoproteins. These include the ability of HDLs to promote the ...

journal_title：Journal of internal medicine

authors： Barter PJ,Rye KA

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Addition of assessment of comorbid diseases ('D') and oxygen saturation ('S') to the CRB-65 score has been recommended to improve its accuracy for risk stratification in community-acquired pneumonia (CAP). The aim of this study was to validate the resulting DS-CRB-65 score in a large cohort of patients with ...

journal_title：Journal of internal medicine

authors： Kolditz M,Ewig S,Schütte H,Suttorp N,Welte T,Rohde G,CAPNETZ study group.

更新日期：2015-08-01 00:00:00

abstract：:Increasing evidence suggests that paraneoplastic syndromes may be mediated by tumour-related cytokine release, although the specific factor(s) involved remain poorly defined. Colony-stimulating factors (CSF) and interleukins (IL) promote colony growth in semi-solid media and, when administered in recombinant form, inc...

journal_title：Journal of internal medicine

authors： Wetzler M,Estrov Z,Talpaz M,Markowitz A,Gutterman JU,Kurzrock R

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:Patients with psoriasis are prone to premature atherosclerosis and increased risk of cardiovascular disease events. However, the prevalence and extent of atherosclerosis in patients with psoriasis are unknown. DESIGN:A cross-sectional study. SETTING AND SUBJECTS:The prevalence and extent of coronary and car...

journal_title：Journal of internal medicine

authors： Yiu KH,Yeung CK,Zhao CT,Chan JC,Siu CW,Tam S,Wong CS,Yan GH,Yue WS,Khong PL,Chan HH,Tse HF

更新日期：2013-03-01 00:00:00

abstract：:The effects of resuscitation on patients who died suddenly out of hospital were evaluated after the introduction of early defibrillation performed by ambulance personnel using semi-automatic defibrillators. Resuscitation attempts were initiated in 548 patients during the 1-year study period. Mean ambulance delay was 7...

journal_title：Journal of internal medicine

authors： Jakobsson J,Rehnqvist N,Nyquist O

更新日期：1989-05-01 00:00:00

abstract：CONTEXT:The classical end-point to terminate the 72-h fast in a patient evaluated for a hypoglycaemic disorder is the occurrence of hypoglycaemic symptoms in association with a low plasma glucose level. However, neither the symptoms nor the plasma glucose level have been exactly defined. OBJECTIVE:To determine whether...

journal_title：Journal of internal medicine

authors： Wiesli P,Brändle M,Schwegler B,Lehmann R,Spinas GA,Schmid C

更新日期：2002-12-01 00:00:00

abstract：:We determined whether ketoconazole prophylaxis might reduce Candida colonization and infections in adult patients with acute leukaemia. During first-remission induction therapy 50 patients were treated with 200 mg ketoconazole administered orally daily, while 57 patients received placebo in a double-blind, randomized ...

journal_title：Journal of internal medicine

authors： Palmblad J,Lönnqvist B,Carlsson B,Grimfors G,Järnmark M,Lerner R,Ljungman P,Nyström-Rosander C,Petrini B,Oberg G

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Findings from animal studies indicate that growth hormone (GH) may stimulate the production of the putative metabolic regulator fibroblast growth factor 21 (FGF21). We investigated whether circulating FGF21 levels are altered in patients with GH deficiency and characterized how levels of this growth factor ar...

journal_title：Journal of internal medicine

authors： Lundberg J,Höybye C,Krusenstjerna-Hafstrøm T,Bina HA,Kharitonenkov A,Angelin B,Rudling M

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Therapeutic paracentesis in patients with cirrhosis is associated with a circulatory dysfunction. Intravenous albumin has been used to prevent the circulatory dysfunction; however, the use of albumin is controversial and costly. Splanchnic vasodilation is mainly responsible for circulatory dysfunction in thes...

journal_title：Journal of internal medicine

authors： Singh V,Kumar B,Nain CK,Singh B,Sharma N,Bhalla A,Sharma AK

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:The RET proto-oncogene is known to be the susceptibility gene for various disease phenotypes, including multiple endocrine neoplasia type 2 (MEN 2). Recent studies have also suggested an involvement of RET in the development of the mammalian kidney. Although kidney agenesis or dysgenesis has been observed in ...

journal_title：Journal of internal medicine

authors： Loré F,Talidis F,Di Cairano G,Renieri A

更新日期：2001-07-01 00:00:00

abstract：:The aim of the present study was to determine the incidence of malignant disease (MD) in adult patients with nephrotic syndrome (NS). Eighty-eight consecutive patients (38 females; 50 males; mean age 47 years; range 15-86) seen in a renal clinic in a 13-year period with NS were studied. Eight of the patients had or de...

journal_title：Journal of internal medicine

authors： Lund L,Jacobsen BA,Schmidt EB

更新日期：1989-09-01 00:00:00

abstract：:Monitoring survival of cancer patients using data collected by population-based cancer registries is an important component of cancer control. In this setting, patient survival is often summarized using net survival, that is survival from cancer if there were no other possible causes of death. Although net survival is...

journal_title：Journal of internal medicine

authors： Eloranta S,Smedby KE,Dickman PW,Andersson TM

更新日期：2021-01-01 00:00:00

abstract：:Multimorbidity, the simultaneous presence of multiple health conditions in an individual, is an increasingly common phenomenon globally. The systematic assessment of the quality of care delivered to people with multimorbidity will be key to informing the organization of services for meeting their complex needs. Yet, c...

journal_title：Journal of internal medicine

authors： Valderas JM,Gangannagaripalli J,Nolte E,Boyd CM,Roland M,Sarria-Santamera A,Jones E,Rijken M

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to identify predictors of weight loss in obese men participating in a 2-year behaviour modification programme. DESIGN:Longitudinal, clinical intervention study of a behaviour modifying weight loss program. SETTING:University Hospital, Stockholm, Sweden. SUBJECTS:Forty-four ...

journal_title：Journal of internal medicine

authors： Näslund E,Andersson I,Degerblad M,Kogner P,Kral JG,Rössner S,Hellström PM

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVES:to examine fatigue variability over time in chronic fatigue syndrome (CFS) and the effect of other symptoms on its predictability. DESIGN:longitudinal cohort study of patients with CFS (Fukuda criteria). SETTING:specialist CFS clinical service. SUBJECTS:phase 1: 100 patients who participated in a study of...

journal_title：Journal of internal medicine

authors： Jones DE,Gray J,Frith J,Newton JL

更新日期：2011-02-01 00:00:00

abstract：:The purpose of this study was to estimate the prevalence of hypertrophic cardiomyopathy (HCM) in 3607 men from the Reykjavik study of 1979-81. Of these, 452 men had an abnormal (group A) and 3155 a normal electrocardiogram. An echocardiographic control group of 128 men was selected from cohorts with a normal electroca...

journal_title：Journal of internal medicine

authors： Agnarsson UT,Hardarson T,Hallgrimsson J,Sigfusson N

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:The contribution of plasma lipids to cardiovascular risk is usually evaluated by measuring plasma concentrations of total cholesterol, triglycerides and HDL cholesterol, and calculating LDL cholesterol concentration. We investigated plasma concentrations of apolipoproteins and lipoprotein particles in women ...

journal_title：Journal of internal medicine

authors： Nielsen NE,Olsson AG,Swahn E

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to examine the effects of treatment with atorvastatin, alpha-tocopherol and the combination of both, on lipoproteins and oxidative stress in dialysis patients. DESIGN AND SETTING:This double-blind randomised placebo-controlled trial was performed at the dialysis department of...

journal_title：Journal of internal medicine

authors： Diepeveen SH,Verhoeven GW,Van Der Palen J,Dikkeschei LD,Van Tits LJ,Kolsters G,Offerman JJ,Bilo HJ,Stalenhoef AF

更新日期：2005-05-01 00:00:00

abstract：:A case of a clinically occult ovarian carcinoma leading to subacute cor pulmonale in a 62-year-old woman is described. The patient was admitted to hospital with increasing respiratory distress. Physical examination and echocardiography showed signs of pulmonary hypertension. She died from circulatory failure. Autopsy ...

journal_title：Journal of internal medicine

authors： Lambert-Jensen P,Mertz H,Nyvad O,Christensen JH

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Community-acquired pneumonia (CAP) is the leading infectious cause of death in developed countries. Risk stratification has previously been difficult. METHODS:Markers of cardiac stress (B-type natriuretic peptide, BNP) and inflammation (C-reactive protein, white blood cell count, procalcitonin) as well as t...

journal_title：Journal of internal medicine

authors： Christ-Crain M,Breidthardt T,Stolz D,Zobrist K,Bingisser R,Miedinger D,Leuppi J,Tamm M,Mueller B,Mueller C

更新日期：2008-08-01 00:00:00

abstract：:It is now well recognized that cardiovascular events (CVE) occur quite commonly, both in the acute phase and in the long-term, in patients with community-acquired pneumonia (CAP). CVE have been noted in up to 30% of patients hospitalized with all-cause CAP. One systematic review and meta-analysis of hospitalized patie...

journal_title：Journal of internal medicine

authors： Feldman C,Normark S,Henriques-Normark B,Anderson R

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVES:the results of experimental studies suggest that vitamin D deficiency activates the renin-angiotensin system and predisposes to hypertension. Results of previous epidemiological studies investigating the association between 25-hydroxyvitamin D [25(OH)D] status and hypertension have not been consistent, perha...

journal_title：Journal of internal medicine

authors： Burgaz A,Byberg L,Rautiainen S,Orsini N,Håkansson N,Arnlöv J,Sundström J,Lind L,Melhus H,Michaëlsson K,Wolk A

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:To examine the relationships between pituitary-adrenal cortical (PA) function, abdominal obesity, hyperinsulinaemia, and dyslipidaemia. DESIGN:A prospective study. SETTING:Helsinki University Central Hospital, Finland. SUBJECTS:Seventy-one healthy males aged 30-55 years. MAIN OUTCOME MEASURES:Insulin sen...

journal_title：Journal of internal medicine

authors： Hautanen A,Räikkönen K,Adlercreutz H

更新日期：1997-06-01 00:00:00

abstract：:In the mitochondrion, inherited defects have been identified in the electron transport system by which ATP is formed, as well as in the transport and metabolism of fuels. Clinical findings in diseases due to these defects can be related to abnormal accumulations of metabolic intermediates and inadequate or inefficient...

journal_title：Journal of internal medicine

authors： Luft R,Landau BR

更新日期：1995-11-01 00:00:00

abstract：:The acquired immunodeficiency syndrome (AIDS) has been associated with abnormalities of adrenocortical function, and hypoaldosteronism due to hyporeninaemic hypoaldosteronism (HHA). We here report the case of a woman with AIDS associated with orthostatic hypotension, persistent hyponatraemia and hyperkalaemia, in whom...

journal_title：Journal of internal medicine

authors： Cobbs R,Pepper GM,Torres JG,Gruenspan HL

更新日期：1991-08-01 00:00:00