Platelet aggregation in diabetic retinopathy.

abstract：:Peripheral blood lymphocytes from patients with chronic lymphocytic leukemia (CLL), lymphoplasmacytoid lymphoma, centrocytic lymphoma and hairy cell leukemia were studied by scanning electron microscopy (SEM). In general, SEM revealed rather homogenous cell populations. Most lymphocytes displayed a moderately villous ...

journal_title：Acta haematologica

authors： Fischer K,Cohnen G,Szaniawski W,Brittinger G

更新日期：1977-03-01 00:00:00

abstract：:Low-dose cytosine arabinoside (ARA-C) induced complete remissions in 6 of 10 patients with acute non-lymphocytic leukaemia (ANLL) who were either refractory to combination chemotherapy with anthracyclines and conventional doses of ARA-C, or were in relapse. Three patients relapsed after 4, 19, and 20 months, whereas 3...

journal_title：Acta haematologica

authors： Krogh Jensen M,Stentoft J

更新日期：1986-01-01 00:00:00

abstract：:A case of lymphoma presenting with features shared by hairy cell leukemia (HCL) and its variant, intermediate lymphocytic lymphoma (ILL) and monocytoid B-cell lymphoma (MBCL) is described. Clinical presentation and the morphological findings observed in peripheral blood and in bone marrow biopsy suggested an HCL; howe...

journal_title：Acta haematologica

authors： Adami F,Chilosi M,Lestani M,Scarpa A,Zambello R,Pomponi F,Semenzato G,Menestrina F

更新日期：1993-01-01 00:00:00

abstract：:Thalidomide acts on the microenvironment of myelodysplastic syndromes (MDS) by influencing cytokine networks, and growing evidence supports thalidomide's usefulness in the management of haematological malignancies, such as MDS. The European Collaboration Group on Myelofibrosis with Myeloid Metaplasia reviewed patients...

journal_title：Acta haematologica

authors： Prentice HG,Sacchi S,Russell N

更新日期：2005-01-01 00:00:00

abstract：:Systematic reviews and meta-analyses have made a major contribution to the evidence-based management of infections in cancer patients. We review the contribution of systematic reviews with regard to antibiotic, antifungal, antiviral and Pneumocystis pneumonia prophylaxis; antibiotic and antifungal treatment of febrile...

journal_title：Acta haematologica

authors： Paul M,Gafter-Gvili A,Goldberg E,Yahav D

更新日期：2011-01-01 00:00:00

abstract：:A case of steroid-resistant acquired pure red-cell aplasia associated with a relative and absolute increase of TG cells is described. Removal of T cells enhanced erythroid colony and burst formation in vitro, and it is suggested that TG cells may be implicated in the pathogenesis of this case of acquired pure red-cell...

journal_title：Acta haematologica

authors： Linch DC,Cawley JC,MacDonald SM,Masters G,Roberts BE,Antonis AH,Waters AK,Sieff C,Lydyard PM

更新日期：1981-01-01 00:00:00

abstract：:A 38-year-old Japanese man had suffered from trichophyton infection for several years. The white blood cell count was 20,300/mm3, including 54% abnormal lymphocytes with irregularly convoluted nuclei. Adult T-cell leukemia (ATL) was diagnosed based on proliferation of CD4-positive lymphocytes, positive anti-HTLV-I ant...

journal_title：Acta haematologica

authors： Okamura T,Shibuya T,Harada M,Niho Y

更新日期：1992-01-01 00:00:00

abstract：:Recently, concerns have been raised regarding the potential impairment of neonatal platelet function and the potential risk of bleeding in neonates born to mothers treated with selective serotonin reuptake inhibitors (SSRI). Our aim was to test whether the platelet function of neonates born to SSRI-treated mothers was...

journal_title：Acta haematologica

authors： Maayan-Metzger A,Kuint J,Lubetsky A,Shenkman B,Mazkereth R,Kenet G

更新日期：2006-01-01 00:00:00

abstract：:A case of Philadelphia-positive (Ph) acute lymphoblastic leukaemia (ALL) in a 40-year-old male is presented. At diagnosis, 80% of bone marrow cells were Ph. Remission with normal blood counts was achieved but the marrow became hypercellular, indicating conversion to chronic granulocytic leukaemia (GCL). The Ph clone p...

journal_title：Acta haematologica

authors： O'Brien DV,Craig JM,Secker-Walker LM,Boughton BJ

更新日期：1993-01-01 00:00:00

abstract：:Eleven patients with acute myeloid leukaemia (AML) in first complete remission (CR) were treated with alfa-2a-interferon (for short 'interferon') maintenance therapy, at a dose of 3 MU twice to thrice weekly subcutaneously. Adjustments were made to maintain neutrophil counts > 1 x 10(9)/l and platelet counts > 100 x 1...

journal_title：Acta haematologica

authors： McSweeney EN,Worman CP,Tsakona CP,Jewel AP,Hoffbrand AV,Milligan DW,Burnett AK,Lewis ML,Goldstone AH

更新日期：1993-01-01 00:00:00

abstract：:Immunologic abnormalities have been described in patients with Hodgkin lymphoma, including autoimmune hemolytic anemia and immune thrombocytopenic purpura. The concurrent diagnoses of Hodgkin lymphoma and acquired aplastic anemia, however, is extremely rare. We report a 56-year-old Japanese female patient with severe ...

journal_title：Acta haematologica

authors： Saitoh T,Matsushima T,Yamane A,Sakuraya M,Irisawa H,Yokohama A,Handa H,Tsukamoto N,Karasawa M,Nojima Y,Murakami H

更新日期：2007-01-01 00:00:00

abstract：:Non-Hodgkin's lymphomas are among the most challenging diseases to treat and their course ranges from very aggressive and rapidly fatal tumors to some of the most indolent, well-tolerated malignancies in man. ...

journal_title：Acta haematologica

authors： Bonadonna G,Bajetta E

更新日期：1987-01-01 00:00:00

abstract：:A 44-year-old Japanese male having refractory anemia with excess of blasts (RAEB) preceding acute myelomonocytic leukemia (AMMoL) with dysplastic marrow eosinophilia (M4Eo in the FAB classification) is reported. Sequential cytogenetic studies revealed a specific chromosomal abnormality, inv(16) (p13q22), when RAEB was...

journal_title：Acta haematologica

authors： Horiike S,Misawa S,Nishida K,Nishigaki H,Tsuda S,Taniwaki M,Takino T,Abe T

更新日期：1989-01-01 00:00:00

abstract：:Agranulocytosis developed in a 20-year-old Greek patient with beta-thalassaemia major, 11 weeks after commencing chelation with the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) and 6 weeks after receiving the drug at a total daily dose of 105 mg/kg. The patient presented with generalised weakness, low-gra...

journal_title：Acta haematologica

authors： al-Refaie FN,Veys PA,Wilkes S,Wonke B,Hoffbrand AV

更新日期：1993-01-01 00:00:00

abstract：:Multiple myeloma and benign monoclonal gammopathies (BMG) are regarded as monoclonal B cell proliferations in which B lymphocyte maturation is blocked in the final stages of the differentiation cycle. Further studies with monoclonal antibodies (MoAbs) of the FMC series and of the 791T/36 MoAb will perhaps provide a fi...

journal_title：Acta haematologica

authors： Ricci C,Cascio G,Canavera R,Basso M,Baldassi R

更新日期：1987-01-01 00:00:00

abstract：:Recombinant alpha-interferons are used as therapeutic agents in an increasing number of benign and malignant disorders. Long-term administration of recombinant alpha-interferon as a maintenance agent is associated with a small number of adverse side-effects which are responsible for patient intolerance of this drug. T...

journal_title：Acta haematologica

authors： Giles FJ,Worman CP,Jewell AP,Goldstone AH

更新日期：1991-01-01 00:00:00

abstract：:Pyrimidine 5'-nucleotidase (P5'N) partial deficiency has been described in several hematological disorders and also in the beta-thalassemic trait. To check if the P5'N deficiency in thalassemia was acquired we used thalassemic red cells (from either homo- or heterozygous subjects), whose P5'N activity was lower than i...

journal_title：Acta haematologica

authors： David O,Vota MG,Piga A,Ramenghi U,Bosia A,Pescarmona GP

更新日期：1989-01-01 00:00:00

abstract：:Twenty-four infants and children suffering from glucose-6-phosphate dehydrogenase (G6PD) deficiency during hemolytic crisis were included in this study. Their ages ranged between 3 and 36 months with a median of 10 months. 22 were males and 2 were females. Fourteen out of them received a single bolus dose of desferrio...

journal_title：Acta haematologica

authors： Khalifa AS,el-Alfy MS,Mokhtar G,Fakeir AA,Khazbak MA,el-Baz F,el-Kholy M

更新日期：1989-01-01 00:00:00

abstract：:In most patients with large granular lymphocyte (LGL) leukemia, the disease appears to progress slowly if at all, and no therapy is generally required. We present a patient with CD3+ CD8+ CD16+ LGL leukemia, who showed a benign clinical course for more than 7 months without therapy, but subsequently developed aggressi...

journal_title：Acta haematologica

authors： Matsubara A,Matsumoto M,Takada K,Hato T,Hasegawa H,Tamai T,Yasukawa M,Fujita S

更新日期：1994-01-01 00:00:00

abstract：:Iron deficiency is the main cause of anemia in both sexes, with women being more commonly affected. Iron therapy is currently considered an effective and safe remedy to replenish the iron storages. Iron can be administrated both orally and intravenously. In particular, intravenous (IV) iron therapy is widely used when...

journal_title：Acta haematologica

authors： Di Girolamo A,Albanesi M,Loconte F,Di Bona D,Caiaffa MF,Macchia L

更新日期：2020-01-01 00:00:00

abstract：:Marginal-zone B cells of the mucosa-associated lymphoid tissue (MALT) are the normal counterpart of the neoplastic cells in MALT lymphoma. In both cases these lymphocytes express surface immunoglobulins, but are negative when stained for B cell associated antigens like CD10 and CD23. Furthermore, the B cell gene rearr...

journal_title：Acta haematologica

authors： Fritscher-Ravens A,Petrasch S,Tiemann M,Wacker H,Dörr T,Kemmeries G,Hilgers W,Reinacher-Schick A,Kunstmann E,Schmiegel W

更新日期：1999-01-01 00:00:00

abstract：:Slow intravenous infusion of Na laurate (NaL) into guinea pigs caused a rapid appearance of platelet aggregates in the arterial blood and a precipitous fall in platelet counts. During the infusion of Na arachidonate (NaA) thrombocytopenia developed slowly, and few and smaller platelet aggregates appeared in the arteri...

journal_title：Acta haematologica

authors： Rafflenbeul D,Zbinden G

更新日期：1977-01-01 00:00:00

abstract：:Factor X inhibitors are rare. The few cases documented in the literature have occurred after viral prodromes, in association with cancer, or after exposure to antibiotics. Acquired factor X deficiencies are also rare and their etiology is largely unknown. We report a new case of a factor X inhibitor and review prior c...

journal_title：Acta haematologica

authors： Gollard R,Rahman S,Ratnasabapathy R

更新日期：2013-01-01 00:00:00

abstract：:We describe a patient with hemophagocytic syndrome resembling malignant histiocytosis which was complicating myelodysplastic disease of 3 years duration. Detailed morphological and ultrastructural studies indicate that the histiocytic component did not demonstrate features of malignancy. A review of other known malign...

journal_title：Acta haematologica

authors： Prokocimer M,Inbal A,Gelber M,Shohat B,Ben Basat M,Shaklai M

更新日期：1985-01-01 00:00:00

abstract：:An ultrastructural study of the aspirated bone marrow of a patient with congenital dyserythropoietic anemia type I is presented. Both in transmission electron microscopy (TEM) and in scanning electron microscopy (SEM) ultrastructural abnormalities of the bone marrow erythroid precursors were seen. These abnormalities ...

journal_title：Acta haematologica

authors： Conde E,Mazo E,Baro J,Lafarga M,Cuadrado MA,Recio M,Zubizarreta A

更新日期：1983-01-01 00:00:00

abstract：:The increased longevity of patients with thalassemia and sickle cell disease (SCD) introduces new clinical challenges due to the accumulation of disease-related morbidity, psychosocial issues and health care adjustments. Patients with thalassemia major now live into adulthood without suffering heart failure but must c...

journal_title：Acta haematologica

authors： Yacobovich J,Tamary H

更新日期：2014-01-01 00:00:00

abstract：:We have studied the amount and intracellular distribution of erythroblastic alkaline and acid phosphatase, nonspecific esterase, and N-acetyl-beta-glucosaminidase in 50 patients with acquired dyserythropoiesis. 19 morphologically normal bone marrow smears served as controls. Alkaline phosphatase was found in all contr...

journal_title：Acta haematologica

authors： Woessner S,Lafuente R,Florensa L,Sans-Sabrafen J

更新日期：1984-01-01 00:00:00

abstract：:Alpha-thalassemia is very common in the Kuwaiti population, but its influence on anemia of pregnancy has not been previously investigated. We have screened a group of 59 anemic (Hb < 11 g/dl) pregnant women for the alpha-thal-2 (-alpha-3.7 kb) deletion which is the commonest alpha-thal allele in this community, using ...

journal_title：Acta haematologica

authors： Diejomaoh FM,Haider MZ,Dalal H,Abdulaziz A,D'Souza TM,Adekile AD

更新日期：2000-01-01 00:00:00

abstract：:All-trans-retinoic acid (ATRA) combined with anthracyclines is currently the standard treatment for acute promyelocytic leukemia (APL). In elderly patients the presence of comorbidities, such as cardiomyopathy or different organ failures, often represents an absolute contraindication to standard chemotherapy. In this ...

journal_title：Acta haematologica

authors： Finizio O,Pezzullo L,Rocco S,Bene L,De Rosa C,Nunziata GR,Mettivier V

更新日期：2007-01-01 00:00:00

abstract：:A hairy-cell leukaemia (HCL) cell line, HCL-O, was established from the peripheral blood of a 62-year-old Japanese patient with a unique variant of HCL strongly expressing CD21, the receptor for the Epstein-Barr virus (EBV). The HCL-O cells expressed antigens similar and dissimilar to those expressed with the original...

journal_title：Acta haematologica

authors： Tokioka T,Shimamoto Y,Nagumo F,Tadano J,Yamaguchi M

更新日期：1994-01-01 00:00:00