Transmission and scanning electron microscopy study on congenital dyserythropoietic anemia type I.

abstract：:2 cases of acute myeloid leukaemia with inclusion bodies are presented. The inclusions were found mainly in the blast cells but could also be encountered in lymphocytes and plasma cells. Cytochemical and ultrastructural studies showed a great resemblance of these inclusions to the ones found in Chediak-Higashi anomaly...

journal_title：Acta haematologica

authors： Efrati P,Nir E,Kaplan H,Dvilanski A

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Immunotherapy using recombinant human interleukin-2 (rIL-2) produces objective responses in a proportion of advanced cancer patients. While early investigators employed intravenous (i.v.) treatment regimens, recent clinical trials applied therapy schedules via subcutaneous (s.c.) injection, mostly in combina...

journal_title：Acta haematologica

authors： Schomburg A,Kirchner H,Atzpodien J

更新日期：1993-01-01 00:00:00

abstract：:A case of isolated lambda-light chain proteinemia and proteinuria is reported. During a 42-month follow-up, no sign of myelomatosis or amyloidosis developed and Bence Jones proteinuria remained nearly of the same magnitude. This case of apparently idiopathic Bence Jones gammopathy, the first lambda-type so far reporte...

journal_title：Acta haematologica

authors： Paladini G,Sala PG,Santini PA

更新日期：1980-01-01 00:00:00

abstract：:There have been many reports of patients with ampulla cardiomyopathy described as takotsubo-shaped cardiomyopathy in the cardiovascular field. This unique cardiomyopathy is characterized by transient apical ballooning and hypokinesis of the left ventricle. We describe 2 cases of ampulla cardiomyopathy associated with ...

journal_title：Acta haematologica

authors： Takeoka Y,Nakamae M,Nakamae H,Hagihara K,Sakamoto E,Nakane T,Koh H,Koh KR,Ohta K,Yamane T,Hino M

更新日期：2007-01-01 00:00:00

abstract：:The last few years have seen an enormous increase in our knowledge on the haematopoietic growth factor erythropoietin (Epo), firstly with its purification and determination of its primary amino acid sequence, and more recently with the isolation of the Epo gene and its expression in mammalian cell lines. This review a...

journal_title：Acta haematologica

authors： Foa P

更新日期：1991-01-01 00:00:00

abstract：:A 59-year-old man with beta-thalassaemia major is unusually well. He has no beta-chains in his haemoglobin but is heterozygous for the genes responsible for alphaA and for alphaG Philadelphia. In addition he is also heterozygous for the genes responsible for gammaF and a new gamma-chain, gamma75(E19) Ile-Thr, named ga...

journal_title：Acta haematologica

authors： Grifoni V,Kamuzora H,Lehmann H,Charlesworth D

更新日期：1975-01-01 00:00:00

abstract：:Hypersensitivity vasculitis occurs in response to various exogenous agents. A case of a serum sickness syndrome with cutaneous vasculitis is described in a patient given an intravenous iron-dextran infusion. ...

journal_title：Acta haematologica

authors： Bielory L

更新日期：1990-01-01 00:00:00

abstract：:In order to study the abnormal differentiation and proliferation of precursor T cells in homosexual men, a study was made of T-cell colony formation in 15 healthy homosexual men without anti-human immunodeficiency virus (HIV) antibody. The colony forming method used was the one-step monolayer technique using phytohema...

journal_title：Acta haematologica

authors： Wakabayashi Y,Sugimoto M,Ishiyama T,Hashimoto M,Horie S,Hirose S

更新日期：1989-01-01 00:00:00

abstract：:We have been studying hematopoietic effects by the tachykinins, which like many other neuropeptides can be expressed in neural and nonneural tissues. Substance P (SP) and neurokinin-A (NK-A), members of the tachykinins are immune and hematopoietic modulators. SP and NK-A are derived from the preprotachykinin-I gene (P...

journal_title：Acta haematologica

authors： Rameshwar P,Gascón P

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Our aim is to determine comorbidities associated with pulmonary hypertension (PHT) in clinically stable sickle-cell disease (SCD) patients and to evaluate left ventricular (LV) and right ventricular (RV) function in those patients. METHODS:Echocardiography was performed in 87 SCD patients that were divided ...

journal_title：Acta haematologica

authors： Akgül F,Yalçin F,Seyfeli E,Uçar E,Karazincir S,Balci A,Gali E

更新日期：2007-01-01 00:00:00

abstract：:Recent molecular biological investigations have shown that genetic information on the short arm of chromosome 17 is frequently deleted or inactivated in acute myeloid leukaemias and a number of solid tumours. In earlier studies we have found clonal occurrence of a 17p deletion (17p-) in patients with refractory anaemi...

journal_title：Acta haematologica

authors： Pedersen B,Kerndrup G

更新日期：1990-01-01 00:00:00

abstract：:The thrombogenicity of prothrombin complex concentrates (PCCs) has been known as a risk factor since their first clinical use about 30 years ago. The development of in vivo models to define the thrombogenic components in PCCs was instrumental in providing a logical basis for selecting in vitro assays to screen for the...

journal_title：Acta haematologica

authors： MacGregor I,McLaughlin L,Drummond O,Prowse C,Ferguson J

更新日期：1995-01-01 00:00:00

abstract：:Richter syndrome (RS) describes the development of high-grade non-Hodgkin's lymphoma (NHL) from low-grade NHL. RS isolated to the brain is very rare and has a poor prognosis. We describe the cases of high-grade large B-cell diffuse NHL in a 56-year-old male with chronic lymphocytic leukemia and in a 71-year-old female...

journal_title：Acta haematologica

authors： Stuplich M,Mayer K,Kim Y,Thanendrarajan S,Simon M,Schäfer N,Glas M,Schmidt-Wolf IG,Herrlinger U

更新日期：2012-01-01 00:00:00

abstract：:Thymopoietin (TP) was originally isolated as a 5-kD 49-aa protein from bovine thymus and was subsequently observed to affect T-cell differentiation and function. We report here the molecular cloning of a murine TP cDNA. The 2,514 bp fragment contains a 630 bp open reading frame that encodes for 210 aa, highly homologo...

journal_title：Acta haematologica

authors： Theodor L,Shoham J,Berger R,Gokkel E,Trachtenbrot L,Simon AJ,Brok-Simon F,Nir U,Ilan E,Zevin-Sonkin D,Friedman E,Rechavi G

更新日期：1997-01-01 00:00:00

abstract：:The fibrinolytic response to surgical trauma was studied longitudinally in 7 pigs by measuring the fibrinolytic activity in the blood and vein wall simultaneously. The results indicated a marked suppression in fibrinolytic activity in the blood which was closely correlated with the activity in the vein wall. This corr...

journal_title：Acta haematologica

authors： Wu AV,Mansfield AO

更新日期：1980-01-01 00:00:00

abstract：:Basic fibroblast growth factor (b-FGF) mediates a variety of biological responses such as angiogenesis and hematopoiesis. We examined the effect of b-FGF on human neutrophil functions in vitro. The surface expression of effector cell molecules on neutrophils was determined by flow cytometry and monoclonal antibodies. ...

journal_title：Acta haematologica

authors： Takagi S,Takahashi K,Katsura Y,Matsuoka T,Ohsaka A

更新日期：2000-01-01 00:00:00

abstract：:A new case of IgE myeloma is described. A 77-year-old woman presented with bone pain and fatigue. Serum protein analysis revealed a paraprotein of the IgE kappa type; bone marrow aspirate and immunofluorescence confirmed the diagnosis; ultrastructural examination showed immature plasma cells. Treatment with prednisone...

journal_title：Acta haematologica

authors： Invernizzi F,Monti G,Caviglia AG,Meroni P,Zanussi C

更新日期：1991-01-01 00:00:00

abstract：:Iron overload is a constant and the more important complication in thalassemia. Serum ferritin concentration accurately reflects body iron stores. A total of 245 thalassemic patients aged 12-55 years were examined, 71 having Hb H disease and 174 beta-thalassemia/Hb E disease. The patients received minimal or no blood ...

journal_title：Acta haematologica

authors： Pootrakul P,Vongsmasa V,La-ongpanich P,Wasi P

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:To review the diagnostic significance, safety and possible risk factors of splenectomy in fever of unknown origin (FUO) with splenomegaly. METHODS:The records of 54 patients with FUO and splenomegaly who underwent splenectomy in our hospital in the past 20 years were reviewed retrospectively. Pathologic find...

journal_title：Acta haematologica

authors： Han B,Yang Z,Yang T,Gao W,Sang X,Zhao Y,Shen T

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Splanchnic vein thrombosis (SVT) is a severe complication of essential thrombocythemia (ET). No clear explanation has been given for the occurrence of thrombosis in this unusual site in patients with ET, but the existence of a specific association between unexplained SVT and the JAK2 mutation has been report...

journal_title：Acta haematologica

authors： Allegra A,Alonci A,Penna G,D'Angelo A,Rizzotti P,Granata A,Musolino C

更新日期：2009-01-01 00:00:00

abstract：:Factor VII deficiency is the least rare among uncommon congenital coagulation disorders. The majority of cases are isolated deficiencies. In some cases, FVII deficiency has been found to be associated with the deficiency in another coagulation factor or with non-coagulation-related abnormalities or defects. The evalua...

journal_title：Acta haematologica

authors： Girolami A,Ruzzon E,Tezza F,Allemand E,Vettore S

更新日期：2007-01-01 00:00:00

abstract：:A 26-year-old female with Ki-1-positive large-cell anaplastic lymphoma is reported. The neoplastic cells were phenotypically and genotypically of T cell origin. Initially, neoplastic cells invaded the skin and lymph nodes, and then invaded the sternal and vertebral bones, ribs and the iliopsoas muscle. Central nervous...

journal_title：Acta haematologica

authors： Tsukamoto N,Morita K,Maehara T,Mitsuhashi M,Karasawa M,Murakami H,Omine M,Naruse T,Yatabe H

更新日期：1992-01-01 00:00:00

abstract：:The activity of ten red blood cell enzymes, including hexokinase, has been measured in 6 Fanconi's anemia patients. In disagreement with previous reports, in no instance were reduced or increased hexokinase levels found. Furthermore, the hexokinase isozymic pattern, thermostability, pH dependence of activity and kinet...

journal_title：Acta haematologica

authors： Magnani M,Novelli G,Stocchi V,Alimena G,Dallapiccola B

更新日期：1984-01-01 00:00:00

abstract：:A mild anemia (hemoglobin 9 g/dl) was found in a patient from Seville (Spain) with marked morphological abnormalities in the peripheral blood smear. The red cell osmotic fragility showed a mild resistance curve with a mean cell fragility (MCF) of 0.375% NaCl (normal = 0.450). Chemical Chemical and thermal instability ...

journal_title：Acta haematologica

authors： Arends T,Garlín G,Guevara JM,Amesty C,Pérez-Bández O,Lorkin PA,Lehmann H,Castillo O

更新日期：1985-01-01 00:00:00

abstract：:A 51-year-old male with acute lymphoblastic leukemia whose course was complicated by primary fibrinolysis and spontaneous rupture of the spleen is described. The patient was treated with various drug combinations: vincristine and prednisone, later by cytosine arabinoside and finally by prednisone, methotrexate and 6-m...

journal_title：Acta haematologica

authors： Gafter U,Mandel EM,Weiss S,Djaldetti M

更新日期：1976-01-01 00:00:00

abstract：:Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is a rare lymphoproliferative disorder characterized by diffuse lymphadenopathy, fever, hepatosplenomegaly, hemolytic anemia, and polyclonal hypergammaglobulinemia. Morphologically, the involved lymph nodes demonstrate complete effacement of the normal arch...

journal_title：Acta haematologica

authors： Sallah S,Gagnon GA

更新日期：1998-01-01 00:00:00

abstract：:The detection and enumeration of sideroblasts depend critically on the method used for iron staining of bone marrow smears. Several methods proposed for semiquantitative evaluation of bone marrow hemosiderin (iron stores) were compared with respect to their suitability for detection of normal and abnormal sideroblasts...

journal_title：Acta haematologica

authors： Baumgartner-Stäubli R,Beck EA

更新日期：1977-01-01 00:00:00

abstract：:In a comparison of 47 patients with Philadelphia-chromosome (Ph)-positive chronic myeloid leukemia (CML) in the Nagasaki University School of Medicine and 64 patients with the same disease in the Roswell Park Memorial Institute, the correlation between the modal number of chromosomes and the therapeutic response and/o...

journal_title：Acta haematologica

authors： Sadamori N,Yao E,Mine M,Tokunaga S,Matsunaga M,Nakamura H,Sasagawa I,Itoyama T,Hayashibara T,Sandberg AA

更新日期：1992-01-01 00:00:00

abstract：:A 67-year-old woman with agnogenic myeloid metaplasia, who underwent splenectomy 1 year after the diagnosis, experienced spontaneous hematologic remission 6 years after splenectomy. Ten months before her anemia improved, peripheral leukocytes no longer showed a shift to the left and peripheral erythroblasts had disapp...

journal_title：Acta haematologica

authors： Shimizu K,Hotta T

更新日期：1990-01-01 00:00:00

abstract：:Hypercalcemia is a significant feature of patients with active multiple myeloma (MM) with extensive bone disease. Among the causes of non-neoplastic hypercalcemia, primary hyperparathyroidism (PHPT) is one of the most common, leading to osteoporosis and bone fractures. Interestingly, some preclinical data indicate tha...

journal_title：Acta haematologica

authors： Notarfranchi L,Marchica V,Dalla Palma B,Pelagatti L,Burroughs-Garcia J,Pedrazzoni M,Ruffini L,Cetani F,Marcocci C,Giuliani N

更新日期：2020-09-09 00:00:00