Red blood cell hexokinase in Fanconi's anemia.

abstract：:A new variant of red cell glucose-6-phosphate dehydrogenase (G6PD) has been found in a Caucasian man with congenital non-spherocytic haemolytic anaemia. This variant has reduced activity, increased thermolability, increased Michaelis constants for glucose-6-phosphate and NADP, slightly increased electrophoretic mobili...

journal_title：Acta haematologica

authors： Mandelli F,Amadori S,De Laurenzi A,Kahn A,Isacchi G,Papa G

更新日期：1977-01-01 00:00:00

abstract：:Thrombopoietin levels in thrombocytopenic mice assayed by 75Se-se-lenomethionine incorporation into blood platelets reached a maximum 12 h after the induction of an acute, immune thrombocytopenia; that was more than twice the value in control mice. The implications of this finding are discussed with reference to the k...

journal_title：Acta haematologica

authors： Nakeff A,Roozendaal KJ

更新日期：1975-01-01 00:00:00

abstract：:Iron overload is a constant and the more important complication in thalassemia. Serum ferritin concentration accurately reflects body iron stores. A total of 245 thalassemic patients aged 12-55 years were examined, 71 having Hb H disease and 174 beta-thalassemia/Hb E disease. The patients received minimal or no blood ...

journal_title：Acta haematologica

authors： Pootrakul P,Vongsmasa V,La-ongpanich P,Wasi P

更新日期：1981-01-01 00:00:00

abstract：:Iron overload due to regular transfusions of packed red cells can cause multiple organ damage. Iron chelation therapy (ICT) is important in patients with aplastic anemia (AA) who require blood transfusions as supportive management. With the introduction of the oral iron chelator deferasirox, ICT has become more widely...

journal_title：Acta haematologica

authors： Lee SE,Yahng SA,Cho BS,Eom KS,Kim YJ,Lee S,Min CK,Kim HJ,Cho SG,Kim DW,Min WS,Park CW,Lee JW

更新日期：2013-01-01 00:00:00

abstract：:Recombinant alpha-interferons are used as therapeutic agents in an increasing number of benign and malignant disorders. Long-term administration of recombinant alpha-interferon as a maintenance agent is associated with a small number of adverse side-effects which are responsible for patient intolerance of this drug. T...

journal_title：Acta haematologica

authors： Giles FJ,Worman CP,Jewell AP,Goldstone AH

更新日期：1991-01-01 00:00:00

abstract：:Agranulocytosis developed in a 20-year-old Greek patient with beta-thalassaemia major, 11 weeks after commencing chelation with the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) and 6 weeks after receiving the drug at a total daily dose of 105 mg/kg. The patient presented with generalised weakness, low-gra...

journal_title：Acta haematologica

authors： al-Refaie FN,Veys PA,Wilkes S,Wonke B,Hoffbrand AV

更新日期：1993-01-01 00:00:00

abstract：:We studied neutrophil chemotaxis and surface membrane glycoproteins in 12 patients suffering from myeloid disorders with abnormal karyotype using in vitro techniques in all 12. Chromosome studies were also carried out virtually simultaneously. We chose to study only patients showing a deficit of chemotaxis (p less tha...

journal_title：Acta haematologica

authors： Ricevuti G,Mazzone A,Notario A

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:We aimed to determine the effects of intravenous iron therapy on blood parameters in pediatric patients who do not tolerate oral iron therapy for any reason. PATIENTS AND METHODS:The patient group consisted of candidates for elective operations requiring blood transfusions in order to raise hemoglobin (Hb) c...

journal_title：Acta haematologica

authors： Akarsu S,Taskin E,Yilmaz E,Yilmaz H,Kilic M,Aygun AD

更新日期：2006-01-01 00:00:00

abstract：:Platelet aggregation in diabetic retinopathy was investigated in a group of 25 patients. An enhanced activity induced by epinephrine and arachidonic acid was found in this group as compared with the controls, whereas in adenosine diphosphate (ADP) platelet aggregation no differences were observed. Spontaneous aggregat...

journal_title：Acta haematologica

authors： Creter D,Pavlotzky F,Savir H

更新日期：1978-01-01 00:00:00

abstract：:The activity of gamma-glutamyl transpeptidase was investigated in normal and leukemia leukocytes. Enzyme activity was positively correlated with the proportion of mature neutrophils and monocytes. In isolated leukocytes from patients with acute myeloid leukemia low values were obtained compared to controls. ...

journal_title：Acta haematologica

authors： Hultberg B,Sjögren U

更新日期：1980-01-01 00:00:00

abstract：:B6D2F1 female mice were intravenously administered 0.4 mg of glucan. 1, 5, 11, and 17 days later, the total nucleated cellularity (TNC) and the numbers of pluripotent hemopoietic stem cells (CFU-s), granulocyte-macrophage progenitor cells (GM-CFC), and erythroid colony-forming (CFU-e) and burst-forming (BFU-e) cells w...

journal_title：Acta haematologica

authors： Patchen ML,MacVittie TJ

更新日期：1983-01-01 00:00:00

abstract：:The first thrombocytopenia cases related to the human immunodeficiency virus (HIV) were described even before its isolation in 1983. Subsequently, multiple mechanisms have been proposed to elucidate the etiology of thrombocytopenia. In addition to other types of cytopenia affecting patients with HIV, thrombocytopenia ...

journal_title：Acta haematologica

authors： Passos AM,Treitinger A,Spada C

更新日期：2010-01-01 00:00:00

abstract：:Littoral cell angioma (LCA) is a rare vascular tumor of the spleen with an unknown etiology and unclear natural history. An association with synchronous malignancy has been described. We report the case of a 54-year-old woman who had progressive splenomegaly over 3 years following resection of a colon adenocarcinoma. ...

journal_title：Acta haematologica

authors： Steensma DP,Morice WG

更新日期：2000-01-01 00:00:00

abstract：:The in vitro immune functions of peripheral blood lymphocytes have been studied in 12 children with beta-thalassaemia major and hypersplenism. The study was performed prior to splenectomy and on the 2nd, 6th, 15th and 30th day after splenectomy. It was found that before splenectomy, patients had low numbers of blood l...

journal_title：Acta haematologica

authors： Mandalenaki-Lambrou K,Vrachnou E,Calogeropoulou C,Ladis V,Kattamis C

更新日期：1987-01-01 00:00:00

abstract：:Posttransplant lymphoproliferative disorders (PTLD) are a potentially life-threatening complication of immunosuppression in transplant recipients. The majority of cases are Epstein-Barr virus-associated lesions of B cell origin. T cell PTLD is rare, particularly in pediatric patients. We present an unusual case of mon...

journal_title：Acta haematologica

authors： Kraus TS,Twist CJ,Tan BT

更新日期：2014-01-01 00:00:00

abstract：:Platelet to leukocyte adhesion phenomena (PLAP) and the phagocytosis of platelets by neutrophils from the EDTA anticoagulated blood samples are described. PLAP was transferable to a normal blood specimen by patient's plasma or serum with or without complement. Further studies revealed in vitro evidence of hereditary p...

journal_title：Acta haematologica

authors： Yoo D,Weems H,Lessin LS

更新日期：1982-01-01 00:00:00

abstract：:Mesenteric panniculitis is a rare idiopathic inflammatory disorder that can lead to sclerosis. We describe a patient with mesenteric panniculitis presenting with abdominal symptoms and autoimmune haemolytic anaemia. The symptoms remitted after splenectomy and gradual steroid taper. This may suggest an autoimmune compo...

journal_title：Acta haematologica

authors： Vidarsson B,Matthíasson P,Agnarsson BA,Onundarson PT

更新日期：2002-01-01 00:00:00

abstract：:Hypersensitivity vasculitis occurs in response to various exogenous agents. A case of a serum sickness syndrome with cutaneous vasculitis is described in a patient given an intravenous iron-dextran infusion. ...

journal_title：Acta haematologica

authors： Bielory L

更新日期：1990-01-01 00:00:00

abstract：:A rare case of acute promyelcytic leukemia (APL) is reported in a 7-year-old boy. The patient displayed the typical features of APL including impaction of the marrow with promyelocytes, marked elevation of the serum vitamin B12 and transcobalamin I levels and a hemorrhagic diathesis. The bleeding diathesis in the case...

journal_title：Acta haematologica

authors： Engelhard D,Yatziv S,Rachmilewitz EA,Polliack A

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Despite encouraging reports concerning the declining prevalence of iron deficiency, this easily preventable disorder is still an existing problem in presumably developed regions. OBJECTIVE:To evaluate the prevalence of iron deficiency and relevant anemia in children residing in Northern Greece and to study ...

journal_title：Acta haematologica

authors： Gompakis N,Economou M,Tsantali C,Kouloulias V,Keramida M,Athanasiou-Metaxa M

更新日期：2007-01-01 00:00:00

abstract：:Red cell glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-chromosomal-linked abnormality often associated with hemolytic anemia. The G6PD variants obtained from 2 unrelated males, one associated with enzyme deficiency and history of hemolytic jaundice, and the other associated with enzyme deficiency but no ...

journal_title：Acta haematologica

authors： Sáenz GF,Chaves M,Berrantes A,Elizondo J,Montero AG,Yoshida A

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Our aim is to determine comorbidities associated with pulmonary hypertension (PHT) in clinically stable sickle-cell disease (SCD) patients and to evaluate left ventricular (LV) and right ventricular (RV) function in those patients. METHODS:Echocardiography was performed in 87 SCD patients that were divided ...

journal_title：Acta haematologica

authors： Akgül F,Yalçin F,Seyfeli E,Uçar E,Karazincir S,Balci A,Gali E

更新日期：2007-01-01 00:00:00

abstract：:In cutaneous T-cell lymphomas (CTCL; mycosis fungoides and Sézary syndrome), the standard therapies tend to be effective but not curative. Single drug therapy with either interferon-alpha or retinoids shows a response rate of about 45%. In this article, we report the results obtained in the treatment of CTCL with a co...

journal_title：Acta haematologica

authors： Dreno B,Celerier P,Litoux P

更新日期：1993-01-01 00:00:00

abstract：:Using enzyme-linked immunosorbent assay (ELISA) and confirmatory immunoprecipitation tests, sera from 640 Nigerians from Lagos and Cross River States were examined for antibodies against HIV. These comprised 570 blood donors and their family members, 56 patients with various haematological conditions and 14 patients w...

journal_title：Acta haematologica

authors： Okpara RA,Akinsete I,Williams EE,Schneider J,Wendler I,Hunsmann G

更新日期：1988-01-01 00:00:00

abstract：:Serum folate levels and unsaturated folate-binding capacity (UFBC) in a mixed population of outpatients and inpatients were analyzed with respect to race, sex, and age. The results supported the relatively high prevalence of subnormal serum folates in patient populations, did not find lower serum folates in the elderl...

journal_title：Acta haematologica

authors： Lawrence VA

更新日期：1983-01-01 00:00:00

abstract：:This paper presents data on the occurrence and pattern of inherited bleeding syndromes (IBS) in Jordan, a hitherto unexplored problem. In 1978, during the first 12 months of a prospective study at a major medical center, 91 patients from 51 families were diagnosed as having IBS. All patients were referred because of m...

journal_title：Acta haematologica

authors： Alsabti EA,Hammadi M

更新日期：1979-01-01 00:00:00

abstract：:To evaluate the effect of granulocyte/colony-stimulating factor (G-CSF) on the onset of the adult respiratory distress syndrome (ARDS), we investigated whether the incidence of ARDS due to pulmonary infection differed between the G-CSF group which received chemotherapy with G-CSF and historical controls without G-CSF....

journal_title：Acta haematologica

authors： Takahashi Y,Kobayashi Y,Chikayama S,Ikeda M,Kondo M

更新日期：1999-01-01 00:00:00

abstract：:2 fatal cases of graft-versus-host disease (GvHD) occurred following blood product transfusions given to patients receiving standard chemotherapy for Hodgkin's disease. GvHD was established by HLA typing, clinical course, and compatible skin biopsy. 23 cases of GvHD following transfusion of blood products from normal ...

journal_title：Acta haematologica

authors： Burns LJ,Westberg MW,Burns CP,Klassen LW,Goeken NE,Ray TL,Macfarlane DE

更新日期：1984-01-01 00:00:00

abstract：:This study was undertaken to define to which platelet components 75Se-methionine is bound after its injection to normal rats, and to study the curves of specific radioactivity of each labelled fraction. It has been shown that, for a part, platelet labelling is due to adsorption of plasma proteins (albumin and fibrinog...

journal_title：Acta haematologica

authors： Dassin E,Najean Y

更新日期：1979-01-01 00:00:00

abstract：:It is unusual to find microorganisms in peripheral blood smears, and their presence is frequently associated with overwhelming sepsis and consequently a poor prognosis. In this report, we demonstrate 4 cases with bacteria in blood smears. Two of them had a fatal outcome, but the other 2 were caused by a contamination ...

journal_title：Acta haematologica

authors： van der Meer W,Verwiel JM,Gidding CE,de Metz M,de Keijzer MH

更新日期：2002-01-01 00:00:00