Acute promyelocytic leukemia in childhood. Report of a case with a review of the literature.

abstract：:High-dose gammaglobulin therapy for patients with idiopathic thrombocytopenic purpura (ITP), introduced by Imbach et al., was applied to 5 adults with chronic refractory ITP to investigate the mechanism of the increase in platelet counts. In 4 of the 5 cases, transient increase in platelet count was observed. Platelet...

journal_title：Acta haematologica

authors： Kurata Y,Tsubakio T,Yonezawa T,Tarui S

更新日期：1983-01-01 00:00:00

abstract：:Among the 193 patients (82 female, 111 male) treated primarily for Hodgkin's disease at our clinic between 1990 and 2001 and followed up until 2003, 42 (22%) had mediastinal bulky tumours (MBTs) by the Cotswolds criteria. The rate of MBT diagnosis was significantly greater in the early stage of the disease, these pati...

journal_title：Acta haematologica

authors： Keresztes K,Lengyel Z,Devenyi K,Vadasz G,Miltenyi Z,Illes A

更新日期：2004-01-01 00:00:00

abstract：:2-Chlorodeoxyadenosine (cladribine, Leustatin) is being used extensively in the treatment of hematologic malignancies, but relatively little is known regarding its toxicity to the normal marrow. Long-term serial hematologic observations have been made on 29 patients with multiple sclerosis undergoing experimental ther...

journal_title：Acta haematologica

authors： Beutler E,Koziol JA,McMillan R,Sipe JC,Romine JS,Carrera CJ

更新日期：1994-01-01 00:00:00

abstract：:A new deletion of the beta-globin gene cluster was characterized in a Turkish family. A 6-year-old male and his father were heterozygotes for this deletion. They presented with mild hypochromic microcytic anemia associated with elevated Hb F (15%) and normal Hb A2 levels (2.0%). This newly described Turkish type (delt...

journal_title：Acta haematologica

authors： Oner R,Oner C,Erdem G,Balkan H,Ozdağ H,Erkan M,Gümrük F,Gürgey A,Altay C

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Despite encouraging reports concerning the declining prevalence of iron deficiency, this easily preventable disorder is still an existing problem in presumably developed regions. OBJECTIVE:To evaluate the prevalence of iron deficiency and relevant anemia in children residing in Northern Greece and to study ...

journal_title：Acta haematologica

authors： Gompakis N,Economou M,Tsantali C,Kouloulias V,Keramida M,Athanasiou-Metaxa M

更新日期：2007-01-01 00:00:00

abstract：:Hypercalcemia is a significant feature of patients with active multiple myeloma (MM) with extensive bone disease. Among the causes of non-neoplastic hypercalcemia, primary hyperparathyroidism (PHPT) is one of the most common, leading to osteoporosis and bone fractures. Interestingly, some preclinical data indicate tha...

journal_title：Acta haematologica

authors： Notarfranchi L,Marchica V,Dalla Palma B,Pelagatti L,Burroughs-Garcia J,Pedrazzoni M,Ruffini L,Cetani F,Marcocci C,Giuliani N

更新日期：2020-09-09 00:00:00

abstract：:Aspirates from bone marrow, spleen and liver were morphologically analysed in 15 untreated patients wich chronic myeloid leukaemia. Megaloblastic changes of the erythroblasts were found to be more common in the spleen and liver than in the bone marrow. A significant increase of 'erythroblastic islands', i.e. erythrobl...

journal_title：Acta haematologica

authors： Sjögren U

更新日期：1976-01-01 00:00:00

abstract：:Littoral cell angioma (LCA) is a rare vascular tumor of the spleen with an unknown etiology and unclear natural history. An association with synchronous malignancy has been described. We report the case of a 54-year-old woman who had progressive splenomegaly over 3 years following resection of a colon adenocarcinoma. ...

journal_title：Acta haematologica

authors： Steensma DP,Morice WG

更新日期：2000-01-01 00:00:00

abstract：:Glucocorticosteroid hormones have been reported either to stimulate or to inhibit human erythropoiesis. We have studied the in vitro effect of hydrocortisone, 10(-6) mol/l, on human BFU-E when stimulated by preconstituted burst-promoting activity (BPA) in a medium conditioned by T lymphocytes. Hydrocortisone was found...

journal_title：Acta haematologica

authors： Morra L,Ponassi A,Moccia F,Mela GS,Ponassi I,Bessone G

更新日期：1989-01-01 00:00:00

abstract：:Residues 124 and 125 of the beta-chain of human haemoglobin are prolyl-prolyl. In the delta-chain, one of these positions is occupied by a glutaminyl, and there has been uncertainty as to which of the two residues is the prolyl and which the glutaminyl. The sequence has now been established to be delta124 Pro - 125 Gl...

journal_title：Acta haematologica

authors： Lehmann H,Casey R

更新日期：1976-01-01 00:00:00

abstract：:10 patients with paroxysmal nocturnal hemoglobinuria were studied taking 109 normal subjects of the Cuban population as control group. 26 HLA antigens corresponding to loci A and B were studied in both groups. Phenotypical frequency of both groups were compared. No statistically significant increase was found for any ...

journal_title：Acta haematologica

authors： Ustariz CR,Arce S,Hernández P,Almaguer M,Pérez S,Ballester JM

更新日期：1980-01-01 00:00:00

abstract：:The detection of cellular antigens in bone marrow sections depends on the method of embedding, the nature of antigen and antibody, antigen retrieval techniques and the sensitivity of the immunohistochemical method. This study evaluated a fluorescyl-tyramide-enhanced immunostaining method on methyl-methacrylate-embedde...

journal_title：Acta haematologica

authors： Gaiser T,Bernhards J

更新日期：2007-01-01 00:00:00

abstract：:An increased bone marrow (BM) apoptosis is one of the mechanisms responsible for the ineffective hematopoiesis of myelodysplastic syndromes (MDS). It is controversial whether the excessive apoptosis in myelodysplasia predominantly involves the subset of progenitor cells or of maturing cells. We investigated the degree...

journal_title：Acta haematologica

authors： Pecci A,Travaglino E,Klersy C,Invernizzi R

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:We aimed to determine the effects of intravenous iron therapy on blood parameters in pediatric patients who do not tolerate oral iron therapy for any reason. PATIENTS AND METHODS:The patient group consisted of candidates for elective operations requiring blood transfusions in order to raise hemoglobin (Hb) c...

journal_title：Acta haematologica

authors： Akarsu S,Taskin E,Yilmaz E,Yilmaz H,Kilic M,Aygun AD

更新日期：2006-01-01 00:00:00

abstract：:The most common single genetic disorder and a major public health issue in Greece and other Mediterranean countries is beta-thalassemia. Current therapeutic approaches for homozygous beta-thalassemia entail blood transfusions and iron chelation therapy with deferoxamine or deferiprone for preventing tissue hemosideros...

journal_title：Acta haematologica

authors： Chaidos A,Makis A,Hatzimichael E,Tsiara S,Gouva M,Tzouvara E,Bourantas KL

更新日期：2004-01-01 00:00:00

abstract：:The unstable haemoglobin, Tb Torino (alpha43(CD1)Phe replaced by Val), has been found for the second time in a family from the Treviso region of Italy. The haemoglobin has a slightly lower oxygen affinity than normal. In both cases, the abnormal haemoglobin is associated with inclusion body anaemia but the course of t...

journal_title：Acta haematologica

authors： Sansone G,Sciarratta GV,Lang A,Lorkin PA,Lehmann H

更新日期：1976-01-01 00:00:00

abstract：:Serum folate levels and unsaturated folate-binding capacity (UFBC) in a mixed population of outpatients and inpatients were analyzed with respect to race, sex, and age. The results supported the relatively high prevalence of subnormal serum folates in patient populations, did not find lower serum folates in the elderl...

journal_title：Acta haematologica

authors： Lawrence VA

更新日期：1983-01-01 00:00:00

abstract：:Monocytoid B cell lymphoma (MBCL) is an immunologically and morphologically well-defined low-grade lymphoma with a predilection for lymph nodes of the parotid region. We describe an association of MBCL with anti-myelin-associated glycoprotein (MAG) polyneuropathy in a 53-year-old male. The diagnosis of stage IV MBCL w...

journal_title：Acta haematologica

authors： Donfrid M,Apostolski S,Suvajdzić N,Janković G,Cemerikić-Martinović V,Atkinson HD,Colovic M

更新日期：2001-01-01 00:00:00

abstract：:A 59-year-old man presented with lymphocytosis with huge splenomegaly. The abnormal lymphocytes had a high nucleoplasm:cytoplasm ratio, a prominent nucleolus and hairy cytoplasmic projections. Immunophenotyping revealed B-cell leukemia with negative reactions to CD5 and CD25. Cytogenetic study showed 46,XY,der(5)t(5;6...

journal_title：Acta haematologica

authors： Dunn P,Shih LY,Ho YS,Tien HF

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Argininemia is an autosomal recessive urea cycle disorder (UCD). Unlike other UCD, hyperammonemia is rarely seen. Patients usually present in childhood with neurological symptoms. Uncommon presentations like neonatal cholestasis or cirrhosis have been reported. Although transient elevations of liver transami...

journal_title：Acta haematologica

authors： Kiykim E,Zubarioglu T,Cansever MS,Celkan T,Häberle J,Aktuglu Zeybek AC

更新日期：2018-01-01 00:00:00

abstract：:This report describes a case of hairy cell leukemia (HCL) occurring with autoimmune chronic active hepatitis (CAH). A 74-year-old woman presented with typical clinical and histologic features of HCL for which splenectomy was performed. 2 years later she developed abnormal liver function tests due to auto-immune CAH. T...

journal_title：Acta haematologica

authors： Begley CG,Mackay IR,Bhathal PS

更新日期：1985-01-01 00:00:00

abstract：:The concentration of plasma vitamin B12 bound to transcobalamin II was measured by two methods: QUSO and Heparin Sepharose (HS). The new HS procedure provided a specific, direct measurement of vitamin B12 bound to both R binder and transcobalamin II in plasma. ...

journal_title：Acta haematologica

authors： Benhayoun S,Adjalla C,Nicolas JP,Guéant JL,Lambert D

更新日期：1993-01-01 00:00:00

abstract：:Primary lymphoma of the female genital tract is very rare. We report the case of a 36-year-old woman who was referred to our hospital because of an indeterminate Pap smear test. The colposcopy showed a thickening of the posterior vaginal wall and various irregular ulcerated nodular lesions. Histological examination, i...

journal_title：Acta haematologica

authors： Guastafierro S,Tedeschi A,Criscuolo C,Celentano M,Cobellis L,Rossiello R,Falcone U

更新日期：2012-01-01 00:00:00

abstract：:Neoplastic cells of 18 patients with multiple myeloma were studied using a panel of 6 monoclonal antibodies to B cells and monospecific antisera against the light chain types of immunoglobulin. OKT10 bound to the myeloma cells of all the patients, although only a small percentage of the cells reacted in 3 instances. M...

journal_title：Acta haematologica

authors： Katagiri S,Yonezawa T,Tamaki T,Kanayama Y,Kuyama J,Ohnishi M,Tsubakio T,Kurata Y,Tarui S

更新日期：1984-01-01 00:00:00

abstract：:The adaptation of cell physiological parameters of erythrocytes of the newborn to erythrocytes in later life was studied by cell separation in an isopycnic dextran density gradient. The cell characteristics during the first trimester of life were followed by repeated determinations. The mean cellular haemoglobin conce...

journal_title：Acta haematologica

authors： Grauel EL,Müller S,Gross J,Syllm-Rapoport I

更新日期：1982-01-01 00:00:00

abstract：:We describe a case of hemolytic anemia with subacute bacterial endocarditis due to Streptococcus sanguis. The major hematological features of the patient were a normocytic anemia with reticulocytosis, an elevation of serum lactate dehydrogenase, and a marked reduction of serum haptoglobin. All these signs of hemolytic...

journal_title：Acta haematologica

authors： Inada T,Shirono K,Tsuda H

更新日期：1995-01-01 00:00:00

abstract：:Treating patients with hemophilia and inhibitors is often problematic. The presence of inhibitors negatively impacts the effectiveness of treatment to achieve hemostasis especially in patients with hemophilia B, owing mainly to allergic reactions to factor IX (FIX) concentrates and the low success rate of immune toler...

journal_title：Acta haematologica

authors： Uchida E,Komori K,Kurata T,Taki M,Sakashita K

更新日期：2020-07-22 00:00:00

abstract：:A patient with acute monoblastic leukemia developed a coagulopathy during chemotherapy. Coagulation studies showed thrombocytopenia, hypofibrinogenemia, high levels of fibrinogen degradation products, a negative protemine test but a normal antithrombin III level. These observations suggest that coagulation abnormaliti...

journal_title：Acta haematologica

authors： Vellenga E,Mulder NH

更新日期：1980-01-01 00:00:00

abstract：:It was found that neutrophils in untreated uraemic patients as well as in subjects on regular dialysis treatment displayed higher activity of acid phosphatase, alkaline phosphatase and peroxidase. Spontaneous reduction of nitro blue tetrazolium (NBT) by granulocytes was also higher in both groups in comparison to cont...

journal_title：Acta haematologica

authors： Sutowicz W,Komorowska Z,Hanicki Z,Cichocki T,Smoleński O

更新日期：1979-01-01 00:00:00

abstract：:To characterize intracellular signaling in peripheral blood (PB) cells of acute myeloid leukemia (AML) patients undergoing pretransplant conditioning with CXCR4 inhibitor plerixafor, granulocyte colony-stimulating factor (G-CSF), and busulfan plus fludarabine (Bu+Flu) chemotherapy, we profiled 153 proteins in 33 funct...

journal_title：Acta haematologica

authors： Zeng Z,Liu W,Benton CB,Konoplev S,Lu H,Wang RY,Chen J,Shpall E,Baggerly KA,Champlin R,Konopleva M

更新日期：2019-01-01 00:00:00