Angioimmunoblastic T cell lymphoma: an unusual presentation of posttransplant lymphoproliferative disorder in a pediatric patient.

abstract：:A case of angioimmunoblastic lymphadenopathy (AILD) with important autoimmune symptoms disappearing under Levamisole therapy is reported. Since Levamisole is thought to have no direct effect on B cells, it is supposed that in AILD it regulates B lymphocyte activity via the restoration of impaired T cell functions. ...

journal_title：Acta haematologica

authors： Andrieu JM,Youinou P,Herzog C

更新日期：1979-01-01 00:00:00

abstract：:A case of acquired haemophilia A presenting with extensive spontaneous bruising and anaemia is reported. The anaemia was due to myelodysplastic syndrome (FAB: refractory anaemia with ringed sideroblasts). A factor-VII:C-specific inhibitor was also found. Prednisone and pyridoxine were given, and the inhibitor became u...

journal_title：Acta haematologica

authors： Lin CK,Liang R,Liu HW,Tse PW,Chan GT

更新日期：1991-01-01 00:00:00

abstract：:Of 34 patients with chronic inflammatory bowel disease (CIBD), 4 developed well-documented episodes of deep-venous thrombosis. All 4 patients had active disease at the time of thrombosis. This group was studied to determine if the tendency to deep-venous thrombosis in patients with CIBD was associated with reduced ant...

journal_title：Acta haematologica

authors： Ghosh S,Mackie MJ,McVerry BA,Galloway M,Ellis A,McKay J

更新日期：1983-01-01 00:00:00

abstract：:The severe endothelial dysfunction in children with acute lymphoblastic leukemia (ALL) can result from the disease itself, from treatment, or from other conditions (e.g. sepsis). The aim of this study was to determine the levels of markers of endothelial activation in children with ALL and to assess their potential pr...

journal_title：Acta haematologica

authors： Hatzipantelis ES,Athanassiou-Metaxa M,Gombakis N,Tzimouli V,Taparkou A,Sidi-Fragandrea V,Garipidou V,Papageorgiou T,Kleta D,Koliouskas DE,Athanasiadou-Piperopoulou F

更新日期：2011-01-01 00:00:00

abstract：:12 thalassaemic patients from Northern Sardinia showing the beta + phenotype were examined by isoelectric focusing and high-performance liquid chromatography techniques for the determination of the variant A gamma T globin chain of the foetal haemoglobin. Two patients (16.7%) were homozygotes for the A gamma T gene va...

journal_title：Acta haematologica

authors： Masala B,Formato M,Manca L,Demuro P,Gallisai D,Dore F,Longinotti M

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/AIMS:The aim of this work was to investigate the efficacy and predictive factors of CLAG treatment in refractory or relapsed (R/R) acute myeloid leukemia (AML) patients. METHODS:Sixty-seven R/R AML patients were enrolled in this prospective cohort study and treated by a CLAG regimen: 5 mg/m2/day cladribine ...

journal_title：Acta haematologica

authors： Wang L,Xu J,Tian X,Lv T,Yuan G

更新日期：2019-01-01 00:00:00

abstract：:Micromegakaryocytes (MMK) were defined morphologically by the cell area, nucleus form and cytoplasmic structure. Bone marrow smears of 7,156 patients were retrospectively analyzed. MMK were found most frequently and abundantly in acute non-lymphatic leukaemia, chronic myeloid leukaemia and pre-leukaemia. The presence ...

journal_title：Acta haematologica

authors： Wiesneth M,Pflieger H,Kubanek B,Heimpel H

更新日期：1980-01-01 00:00:00

abstract：:Eltrombopag is a thrombopoietin receptor agonist frequently used to manage immune thrombocytopenia and aplastic anemia. At the high doses used for aplastic anemia, but not the doses used for immune thrombocytopenia, eltrombopag can cause reddish-brown discoloration of plasma, which can interfere with bilirubin measure...

journal_title：Acta haematologica

authors： Al-Samkari H,Goodarzi K

更新日期：2020-07-22 00:00:00

abstract：:The immunological phenotypes of lymphocytes and myeloma cells in 48 patients with multiple myeloma (MM) were analyzed using a panel of monoclonal antibodies (mAbs). Myeloma cells were positive for OKT10, BL3, PCA1 and BA2. In a few cases, they were also positive for the B cell-associated antigens J5, B1 and I2. Eight ...

journal_title：Acta haematologica

authors： Shimazaki C,Fried J,Perez AG,Scheinberg DA,Atzpodien J,Wang CY,Wisniewolski R,Clarkson BD

更新日期：1990-01-01 00:00:00

abstract：:Preliminary results from the first 21 patients of a group of 30 with International Federation of Gynaecology and Obstetrics (FIGO) stage II-IV epithelial ovarian carcinoma and anaemia are reported. Patients entered this open-label, comparative-group, out-patient study and were randomized to receive conventional suppor...

journal_title：Acta haematologica

authors： James RD,Wilkinson PM,Belli F,Welch R,Cowan R

更新日期：1992-01-01 00:00:00

abstract：:In a previous study, we evaluated efficacy of repeated antilymphocyte globulin (ALG) treatment for patients with severe aplastic anemia not responding to an initial ALG treatment or relapsing after initial response to ALG. We now searched in the same cohort of patients for differences between patients who responded to...

journal_title：Acta haematologica

authors： Viollier R,Tichelli A

更新日期：2000-01-01 00:00:00

abstract：:This paper presents data on the occurrence and pattern of inherited bleeding syndromes (IBS) in Jordan, a hitherto unexplored problem. In 1978, during the first 12 months of a prospective study at a major medical center, 91 patients from 51 families were diagnosed as having IBS. All patients were referred because of m...

journal_title：Acta haematologica

authors： Alsabti EA,Hammadi M

更新日期：1979-01-01 00:00:00

abstract：:Significant DNA polymorphisms have been reported in the beta-globin gene cluster of epsilon-G gamma-A gamma-psi beta-delta-beta-gene region, in normal (Hb AA) individuals and in patients with sickle cell anaemia (SCA). Investigations of the extent of the DNA polymorphisms in the beta A- and beta S-globin gene cluster ...

journal_title：Acta haematologica

authors： el-Hazmi MA,Bahakim HM,Warsy AS

更新日期：1992-01-01 00:00:00

abstract：:A subpopulation with alkaline phosphatase activity and neutrophilic granules was found in leukemic monocytes from a child with acute monocytic leukemia (M5B). Almost all leukemic cells were strongly positive for nonspecific esterase and phagocytized opsonized zymosans. These findings suggest that the subpopulation are...

journal_title：Acta haematologica

authors： Tomonaga M,Ichimaru M,Tsuji Y

更新日期：1984-01-01 00:00:00

abstract：:The objective of this study was to assess the pharmacokinetics of rhG-CSF after a single intraperitoneal injection 2 h post-TBI in B6D2F1 lethally irradiated mice and to analyze the effect of rhG-CSF on the endogenous response of interleukin-3 (IL-3), interleukin-6 (IL-6) and granulocyte-macrophage colony-stimulating ...

journal_title：Acta haematologica

authors： Kádár E,Sureda A,Mangues MA,Inglés-Esteve J,Valls A,García J

更新日期：1997-01-01 00:00:00

abstract：:We investigated double (specific and nonspecific) esterase (DE) staining in marrow cells of 237 patients with the myelodysplastic syndromes (MDS). Additional abnormalities of neutrophilic granules were examined cytochemically and immunocytochemically for myeloperoxidase activity and antigen elastase, lactoferrin and C...

journal_title：Acta haematologica

authors： Elghetany MT,Peterson B,MacCallum J,Nelson DA,Varney JF,Sullivan AK,Silverman LR,Schiffer CA,Davey FR,Bloomfield CD

更新日期：1998-01-01 00:00:00

abstract：:The most common single genetic disorder and a major public health issue in Greece and other Mediterranean countries is beta-thalassemia. Current therapeutic approaches for homozygous beta-thalassemia entail blood transfusions and iron chelation therapy with deferoxamine or deferiprone for preventing tissue hemosideros...

journal_title：Acta haematologica

authors： Chaidos A,Makis A,Hatzimichael E,Tsiara S,Gouva M,Tzouvara E,Bourantas KL

更新日期：2004-01-01 00:00:00

abstract：:Avascular necrosis (AVN) of the hip is a common cause of morbidity in sickle cell disease (SCD). Its prevalence increases with age and predisposing factors include coexistent alpha-thalassemia trait, frequent vaso-occlusive crisis and a high hematocrit (Hct). SCD is relatively mild among Kuwaiti patients because of th...

journal_title：Acta haematologica

authors： Adekile AD,Gupta R,Yacoub F,Sinan T,Al-Bloushi M,Haider MZ

更新日期：2001-01-01 00:00:00

abstract：:A rare case of Hodgkin's disease which initially presented with a thyroid tumor in an 18-year-old-man is reported. The tumor involved most of the thyroid gland but was well demarcated, and the border between the tumor and the remnants of the thyroid gland was relatively clear, suggesting secondary Hodgkin's disease in...

journal_title：Acta haematologica

authors： Nakamura S,Mizukami Y,Yokoyama K,Saito Y,Ohtake S,Matsuda T

更新日期：1997-01-01 00:00:00

abstract：:Factor VIII (FVIII) inhibitor antibodies are produced against functional epitopes of FVIII in about 30% of severe hemophilia A patients leading to inhibition of its procoagulant activity. The Bethesda assay, the most commonly used method to measure FVIII inhibitors, based on inhibition of coagulant activity of FVIII, ...

journal_title：Acta haematologica

authors： Towfighi F,Gharagozlou S,Sharifian RA,Kazemnejad A,Esmailzadeh K,Managhchi MR,Shokri F

更新日期：2005-01-01 00:00:00

abstract：:RAS mutations are found in about 25% of acute myeloid leukemia (AML) cases. The importance of these changes is unknown. If RAS mutations confer growth advantage to leukemia subclones in which they emerge, substantially more nonconservative than conservative mutations should be found. The incidence of conservative muta...

journal_title：Acta haematologica

authors： Aurer I,Labar B,Nemet D,Ajduković R,Bogdanić V,Gale RP

更新日期：1994-01-01 00:00:00

abstract：:A 74-year-old woman was treated by lithium carbonate 3 x 300 mg per day for drug-induced aplastic anemia. After 8 days, she suddenly developed severe impairment of consciousness with myoclonias and hypertonia which persisted during 10 days despite lithium withdrawal and sodium chloride infusion. Slight disorders of wa...

journal_title：Acta haematologica

authors： Efira A,van Laethem Y,Ectors M,Unger J

更新日期：1980-01-01 00:00:00

abstract：:Janus kinases are critical components of signaling pathways that regulate hematopoiesis. Mutations of the non-receptor tyrosine kinase JAK2 are found in many BCR-ABL-negative myeloproliferative neoplasms. Preclinical results support that JAK2 inhibitors could show efficacy in treating chronic myeloproliferative neopla...

journal_title：Acta haematologica

authors： Ringel F,Kaeda J,Schwarz M,Oberender C,Grille P,Dörken B,Marque F,Manley PW,Radimerski T,le Coutre P

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:The aim of this investigation was to study the effect of vitamin E treatment in oxidative stress of red and white cells of beta-thalassaemia intermedia patients. METHODS:Nine patients undergoing occasional transfusions (5 females/4 males), median age 39 years (range 15-74), were recruited for oral daily admi...

journal_title：Acta haematologica

authors： Pfeifer WP,Degasperi GR,Almeida MT,Vercesi AE,Costa FF,Saad ST

更新日期：2008-01-01 00:00:00

abstract：:Differentiation of rapidly binding coagulation factor inhibitors from antiphospholipid antibodies is a challenge for the hemostaseologic laboratory, especially with respect to the different therapeutic consequences. Several immunological and functional assays for the diagnosis of these disorders have been proposed. He...

journal_title：Acta haematologica

authors： Steinbrueckner B,Steigerwald U,Keller F,Ordung R,Neuenroth L,Reuther J,Klinker H,Schwender S

更新日期：1998-01-01 00:00:00

abstract：:High-dose gammaglobulin therapy for patients with idiopathic thrombocytopenic purpura (ITP), introduced by Imbach et al., was applied to 5 adults with chronic refractory ITP to investigate the mechanism of the increase in platelet counts. In 4 of the 5 cases, transient increase in platelet count was observed. Platelet...

journal_title：Acta haematologica

authors： Kurata Y,Tsubakio T,Yonezawa T,Tarui S

更新日期：1983-01-01 00:00:00

abstract：:It was found that neutrophils in untreated uraemic patients as well as in subjects on regular dialysis treatment displayed higher activity of acid phosphatase, alkaline phosphatase and peroxidase. Spontaneous reduction of nitro blue tetrazolium (NBT) by granulocytes was also higher in both groups in comparison to cont...

journal_title：Acta haematologica

authors： Sutowicz W,Komorowska Z,Hanicki Z,Cichocki T,Smoleński O

更新日期：1979-01-01 00:00:00

abstract：:Although multiple myeloma (MM) remains an incurable disease, its treatment has improved over the past decade. This improvement has been at least in part due to the introduction of novel antimyeloma agents with new mechanisms of action, including those that target both myeloma cells and the tumor microenvironment, with...

journal_title：Acta haematologica

authors： Cibeira MT,Mercadal S,Arenillas L,Muntañola A,Salamero O,Bladé J

更新日期：2006-01-01 00:00:00

abstract：:Analysis of donor chimerism has become a routine method for the documentation of engraftment after allogeneic hematopoietic stem cell transplantation (HSCT). In recent years several groups have also focused on the application of this technique for the detection of relapsing disease after allogeneic HSCT. This review a...

journal_title：Acta haematologica

authors： Thiede C,Bornhäuser M,Ehninger G

更新日期：2004-01-01 00:00:00

abstract：:It has been suggested that CD44 mediates adhesive interactions between hematopoietic progenitor cells and the stromal microenvironment. Ligands of CD44 include several extracellular matrix components, such as hyaluronic acid and fibronectin. Antibodies against CD44 have been shown to induce homotypic T cell aggregatio...

journal_title：Acta haematologica

authors： Oostendorp RA,Spitzer E,Dörmer P

更新日期：1996-01-01 00:00:00