Thalassemia major and sickle cell disease in adolescents and young adults.

Abstract:

:The increased longevity of patients with thalassemia and sickle cell disease (SCD) introduces new clinical challenges due to the accumulation of disease-related morbidity, psychosocial issues and health care adjustments. Patients with thalassemia major now live into adulthood without suffering heart failure but must confront delayed puberty, impaired fertility and progressive bone disease. The increased survival in SCD brings to the front previously unrecognized complications including pulmonary hypertension, silent cerebral infarcts and also reproductive dysfunction. Adolescents and young adults (AYAs) have age-related psychosocial needs in their transition from the pediatric health care environment to the adult system. In this review we present the uniquely age-related medical issues facing the AYA thalassemia and SCD cohort in their transition into adulthood.

journal_name

Acta Haematol

journal_title

Acta haematologica

authors

Yacobovich J,Tamary H

doi

10.1159/000360235

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

340-7

issue

3-4

eissn

0001-5792

issn

1421-9662

pii

000360235

journal_volume

132

pub_type

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