Immunoregulation and differentiation markers in monoclonal gammopathies.

abstract：:The level of granulocyte-macrophage colony-stimulating factor (GM-CSF) in the cerebrospinal fluid from 14 infants and children with meningitis and 6 patients who suffered other diseases besides meningitis was measured by our sensitive enzyme linked immunosorbent assay for GM-CSF. The minimal detection level of GM-CSF ...

journal_title：Acta haematologica

authors： Shimoda K,Okamura S,Omori F,Mizuno Y,Hara T,Aoki T,Akeda H,Ueda K,Niho Y

更新日期：1991-01-01 00:00:00

abstract：:While sickle cell disease (SCD) is generally mild in most Kuwaitis, because of their elevated fetal Hb levels, avascular necrosis of the femoral head (AVNFH) appears to be a common complication. It was recently documented in 26.7% of Kuwaiti children with SCD. There have, however, been no previous studies of adult pat...

journal_title：Acta haematologica

authors： Marouf R,Gupta R,Haider MZ,Al-Wazzan H,Adekile AD

更新日期：2003-01-01 00:00:00

abstract：:Aspirates from bone marrow, spleen and liver were morphologically analysed in 15 untreated patients wich chronic myeloid leukaemia. Megaloblastic changes of the erythroblasts were found to be more common in the spleen and liver than in the bone marrow. A significant increase of 'erythroblastic islands', i.e. erythrobl...

journal_title：Acta haematologica

authors： Sjögren U

更新日期：1976-01-01 00:00:00

abstract：:A hemophilia B patient, seropositive for HIV antibodies since 1984, came to us in March 1989 with a severe necrotizing lesion of the nose. It was an erythematous lesion and looked like rhinophyma. Microbiological examination of the skin biopsy showed the presence of Cryptococcus neoformans. At the time of the study, t...

journal_title：Acta haematologica

authors： Mares M,Sartori MT,Carretta M,Bertaggia A,Girolami A

更新日期：1990-01-01 00:00:00

abstract：:6 patients with acute leukemia are described. All of them suffered from high temperature and malaise, and showed negative urine and blood cultures. High doses of gentamicin, cephalothin and cerebenicillin failed to lower the fever. The temperature became normal after administration of chloramphenicol (CAP) 2.0 g/day. ...

journal_title：Acta haematologica

authors： Klein B,Bessler H,Lewinski UH,Cohen AM,Djaldetti M

更新日期：1980-01-01 00:00:00

abstract：:An unusual complication of chronic lymphocytic leukemia (CLL) is reported. The patient, a 79-year-old man, had a long standing history of CLL, that had been complicated by the development of a Guillain-Barré-like syndrome and a peripheral biclonal gammopathy. The biclonal immunoglobulins identified in the serum were I...

journal_title：Acta haematologica

authors： Ruiz P,Moezzi M,Chamizo W,Ganjei P,Whitcomb CC,Rey LC

更新日期：1992-01-01 00:00:00

abstract：:A comparative study of karyotypes, hematological variables and neutrophil alkaline phosphatase (NAP) was performed in 106 parents (53 couples) of children with free, homogeneous trisomy 21 and of 220 parents (110 couples) of normal children. In the parents of trisomy 21 children we found a significant increase of the ...

journal_title：Acta haematologica

authors： Grozdea J,Bourrouillou G,Mounie C,Colombies P

更新日期：1980-01-01 00:00:00

abstract：:Many bovine leukemic lymphocytes produce virus particles when kept in survival cultures in Eagle's Minimum Essential Medium supplemented with 20 percent of inactivated fetal calf serum. Virus particles equilibrate at a density of 1.16 g/ml in sucrose gradients and at a density of 1.12 g/ml in metrizamide gradients. Si...

journal_title：Acta haematologica

authors： Kettmann R,Mammerickx M,Dekegel D,Ghysdael J,Portetelle D,Burny A

更新日期：1975-01-01 00:00:00

abstract：:Thrombopoietin levels in thrombocytopenic mice assayed by 75Se-se-lenomethionine incorporation into blood platelets reached a maximum 12 h after the induction of an acute, immune thrombocytopenia; that was more than twice the value in control mice. The implications of this finding are discussed with reference to the k...

journal_title：Acta haematologica

authors： Nakeff A,Roozendaal KJ

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:It is a common belief among women that iron compounds have unpleasant gastrointestinal side effects. OBJECTIVE:To assess the gastrointestinal side effects of iron prophylaxis in pregnancy. METHODS:A randomized, double-blind study comprising 404 healthy pregnant women allocated to four groups taking ferrous...

journal_title：Acta haematologica

authors： Milman N,Byg KE,Bergholt T,Eriksen L

更新日期：2006-01-01 00:00:00

abstract：:Preliminary results from the first 21 patients of a group of 30 with International Federation of Gynaecology and Obstetrics (FIGO) stage II-IV epithelial ovarian carcinoma and anaemia are reported. Patients entered this open-label, comparative-group, out-patient study and were randomized to receive conventional suppor...

journal_title：Acta haematologica

authors： James RD,Wilkinson PM,Belli F,Welch R,Cowan R

更新日期：1992-01-01 00:00:00

abstract：:A case of acquired haemophilia A presenting with extensive spontaneous bruising and anaemia is reported. The anaemia was due to myelodysplastic syndrome (FAB: refractory anaemia with ringed sideroblasts). A factor-VII:C-specific inhibitor was also found. Prednisone and pyridoxine were given, and the inhibitor became u...

journal_title：Acta haematologica

authors： Lin CK,Liang R,Liu HW,Tse PW,Chan GT

更新日期：1991-01-01 00:00:00

abstract：:Platelet aggregation in diabetic retinopathy was investigated in a group of 25 patients. An enhanced activity induced by epinephrine and arachidonic acid was found in this group as compared with the controls, whereas in adenosine diphosphate (ADP) platelet aggregation no differences were observed. Spontaneous aggregat...

journal_title：Acta haematologica

authors： Creter D,Pavlotzky F,Savir H

更新日期：1978-01-01 00:00:00

abstract：:Upper-extremity deep venous thrombosis (UEDVT) is an increasingly important clinical problem in children. These events are classified as primary or secondary, with the latter being the most common and usually associated with the presence of a central venous line. Among primary UEDVT, the so-called Paget-Schroetter syn...

journal_title：Acta haematologica

authors： Brandão LR,Williams S,Kahr WH,Ryan C,Temple M,Chan AK

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Our aim is to determine comorbidities associated with pulmonary hypertension (PHT) in clinically stable sickle-cell disease (SCD) patients and to evaluate left ventricular (LV) and right ventricular (RV) function in those patients. METHODS:Echocardiography was performed in 87 SCD patients that were divided ...

journal_title：Acta haematologica

authors： Akgül F,Yalçin F,Seyfeli E,Uçar E,Karazincir S,Balci A,Gali E

更新日期：2007-01-01 00:00:00

abstract：:To characterize intracellular signaling in peripheral blood (PB) cells of acute myeloid leukemia (AML) patients undergoing pretransplant conditioning with CXCR4 inhibitor plerixafor, granulocyte colony-stimulating factor (G-CSF), and busulfan plus fludarabine (Bu+Flu) chemotherapy, we profiled 153 proteins in 33 funct...

journal_title：Acta haematologica

authors： Zeng Z,Liu W,Benton CB,Konoplev S,Lu H,Wang RY,Chen J,Shpall E,Baggerly KA,Champlin R,Konopleva M

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:We aimed to determine the effects of intravenous iron therapy on blood parameters in pediatric patients who do not tolerate oral iron therapy for any reason. PATIENTS AND METHODS:The patient group consisted of candidates for elective operations requiring blood transfusions in order to raise hemoglobin (Hb) c...

journal_title：Acta haematologica

authors： Akarsu S,Taskin E,Yilmaz E,Yilmaz H,Kilic M,Aygun AD

更新日期：2006-01-01 00:00:00

abstract：:Haemoglobin synthesis was studied in bone marrow erythroblasts and in reticulocytes of 4 children with beta O-thalassaemia major and of 7 children with beta +-thalassaemia major. In patients with beta O-thalassaemia the gamma/a ratio was found to be lower in bone marrow than in peripheral blood. On the contrary, in pa...

journal_title：Acta haematologica

authors： Musumeci S,Schilirò G,Romeo MA,Pizzarelli G,Fischer A,Russo G

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Biphenotypic acute leukemia (BAL) is a rare type of acute leukemia that presents with a high degree of heterogeneity and is not well defined. METHODS:We identified 51 cases (3%) of BAL from 1,693 newly diagnosed acute leukemia patients according to the EGIL scoring system. The immunophenotyping, cytogenetic...

journal_title：Acta haematologica

authors： Zhang Y,Wu D,Sun A,Qiu H,He G,Jin Z,Tang X,Miao M,Fu Z,Han Y

更新日期：2011-01-01 00:00:00

abstract：:A 64-year-old man with multiple sclerosis developed a circulating anticoagulant. Three immunoglobulin fractions (I = IgG; II =IgG+IgA; III = IgM) were separated from patient serum by 33-percent ammonium sulfate precipitation and DEAE-52 cellulose column chromatography. Fractions I (IgG) and II (IgG+IgA) had factor VII...

journal_title：Acta haematologica

authors： Moake JL,Kent CJ,Meta LD,Wright LC

更新日期：1976-01-01 00:00:00

abstract：:Cancer patients not undergoing treatment and without a history of venous thrombosis do not, as a general rule, require prophylaxis. However, venous thromboembolism is of sufficient magnitude in patients undergoing treatment for cancer for thromboprophylaxis to be routinely employed. The mainstay of primary prevention ...

journal_title：Acta haematologica

authors： Thodiyil PA,Walsh DC,Kakkar AK

更新日期：2001-01-01 00:00:00

abstract：:Sera from 154 hemophiliacs, including 132 with hemophilia A and 22 with hemophilia B, were examined for antibodies against human T cell lymphotropic virus type III (HTLV-III) and type I by strip radioimmunoassay based on the Western blotting technique. Sixty-two patients lived in Kyushu, a known endemic area of HTLV-I...

journal_title：Acta haematologica

authors： Hattori T,Ikematsu S,Chosa T,Yamamoto S,Matsuoka M,Fukutake K,Robert-Guroff M,Takatsuki K

更新日期：1987-01-01 00:00:00

abstract：:High-dose gammaglobulin therapy for patients with idiopathic thrombocytopenic purpura (ITP), introduced by Imbach et al., was applied to 5 adults with chronic refractory ITP to investigate the mechanism of the increase in platelet counts. In 4 of the 5 cases, transient increase in platelet count was observed. Platelet...

journal_title：Acta haematologica

authors： Kurata Y,Tsubakio T,Yonezawa T,Tarui S

更新日期：1983-01-01 00:00:00

abstract：:Two family members (daughter and mother) with a bleeding disorder showed prolonged bleeding time and activated partial thromboplastin time associated with decreased plasma levels of factor VIII procoagulant activity, factor VIII-related antigen, and factor VIII-ristocetin cofactor activity. The ristocetin-induced plat...

journal_title：Acta haematologica

authors： Niiya K,Kubonishi I,Taguchi H,Miyoshi I

更新日期：1984-01-01 00:00:00

abstract：:An ultrastructural study of the aspirated bone marrow of a patient with congenital dyserythropoietic anemia type I is presented. Both in transmission electron microscopy (TEM) and in scanning electron microscopy (SEM) ultrastructural abnormalities of the bone marrow erythroid precursors were seen. These abnormalities ...

journal_title：Acta haematologica

authors： Conde E,Mazo E,Baro J,Lafarga M,Cuadrado MA,Recio M,Zubizarreta A

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:We investigated the prevalence of opportunistic infections in HIV-infected women according to transferrin (TF) phenotype. METHODS:We conducted a cross-sectional study among 200 HIV-positive women in the Butare University Teaching Hospital in Rwanda. TF phenotypes were determined using starch gel electrophore...

journal_title：Acta haematologica

authors： Masaisa F,Gahutu JB,Mukiibi J,Delanghe J,Philippé J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Despite encouraging reports concerning the declining prevalence of iron deficiency, this easily preventable disorder is still an existing problem in presumably developed regions. OBJECTIVE:To evaluate the prevalence of iron deficiency and relevant anemia in children residing in Northern Greece and to study ...

journal_title：Acta haematologica

authors： Gompakis N,Economou M,Tsantali C,Kouloulias V,Keramida M,Athanasiou-Metaxa M

更新日期：2007-01-01 00:00:00

abstract：:In most patients with large granular lymphocyte (LGL) leukemia, the disease appears to progress slowly if at all, and no therapy is generally required. We present a patient with CD3+ CD8+ CD16+ LGL leukemia, who showed a benign clinical course for more than 7 months without therapy, but subsequently developed aggressi...

journal_title：Acta haematologica

authors： Matsubara A,Matsumoto M,Takada K,Hato T,Hasegawa H,Tamai T,Yasukawa M,Fujita S

更新日期：1994-01-01 00:00:00

abstract：:Natural killer (NK) cell activity against K562 cell targets and the distribution of T cell subpopulations were investigated in the peripheral blood of 25 patients affected by beta thalassemia major, 18 clinically healthy heterozygotes, and 25 age-matched normal subjects. It was found that thalassemia major patients di...

journal_title：Acta haematologica

authors： Neri A,Brugiatelli M,Iacopino P,Callea V,Ronco F

更新日期：1984-01-01 00:00:00

abstract：:Cardiac scintigraphy has been performed in 60 beta-thalassaemia major patients aged 8-35 years who received regular blood transfusions and subcutaneous desferrioxamine (DFX) chelation. Fifty-seven showed no clinical, radiological or electrocardiographic evidence of heart disease and 3 had clinically apparent cardiac f...

journal_title：Acta haematologica

authors： Aldouri MA,Wonke B,Hoffbrand AV,Flynn DM,Ward SE,Agnew JE,Hilson AJ

更新日期：1990-01-01 00:00:00