Biochemical approach to bovine leukemia.

abstract：:A 69-year-old woman with typical thrombotic thrombocytopenic purpura is reported, who was treated successfully by plasma exchange. An initial chromosomal analysis of peripheral blood lymphocytes revealed abnormal patterns of 45, XO/46, XX/47, XXX; a second analysis showed 45, XO/46, XX/47, XXX/47, XX + 21, and a third...

journal_title：Acta haematologica

authors： Itoh Y,Taniguchi T,Takeyama N,Kuriki H,Tanaka T

更新日期：1990-01-01 00:00:00

abstract：:A 12-year-old male of Chinese ancestry had life-long hemolytic anemia attributed to alpha-thalassemia. Restriction endonuclease mapping of his DNA revealed that in reality, he had three alpha-globin loci, but he was homozygous for pyruvate kinase deficiency. The new pyruvate kinase variant carried by this patient was ...

journal_title：Acta haematologica

authors： Beutler E,Forman L

更新日期：1983-01-01 00:00:00

abstract：:Hypersensitivity vasculitis occurs in response to various exogenous agents. A case of a serum sickness syndrome with cutaneous vasculitis is described in a patient given an intravenous iron-dextran infusion. ...

journal_title：Acta haematologica

authors： Bielory L

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:The treatment of relapsed/refractory (R/R) peripheral T cell lymphoma (PTCL) is limited to a few agents. Romidepsin, a histone deacetylase inhibitor, was approved for PTCL treatment as a single agent in the R/R setting, yet with partial efficacy. Several attempts to combine romidepsin with other chemotherapy...

journal_title：Acta haematologica

authors： Nachmias B,Shaulov A,Lavie D,Goldschmidt N,Gural A,Saban R,Lebel E,Gatt ME

更新日期：2019-01-01 00:00:00

abstract：:Serological and biochemical studies were performed on M components isolated from 3 patients with transitional cell carcinoma of the urinary bladder (TCC). All were IgG1(K) proteins. 2 of the 3 belonged to the VKI subgroup, and these 2 also possessed cross-reactive idiotypic determinants. These findings are consistent ...

journal_title：Acta haematologica

authors： Pick AI,Wang AC,Frohlichman R,Fudenberg HH

更新日期：1982-01-01 00:00:00

abstract：:Using labelled erythrocytes and human serum albumin, the volume of circulating erythrocytes and plasma was determined in the spleen and individual parts of the skeleton of mice under physiological conditions and 48 h after X-irradiation with a dose of 2,87 Gy. The results are significant for the interpretation of the ...

journal_title：Acta haematologica

authors： Vácha J,Holá J,Dungel J,Znojil V

更新日期：1980-01-01 00:00:00

abstract：:Fourteen patients with hematologic neoplasia (11 acute myeloid leukemias, 2 non-Hodgkin's lymphomas and 1 blast crisis of chronic myeloid leukemia) who underwent high-dose cytosine arabinoside (HIDARAC) therapy with or without sequential asparaginase (ASNase) were investigated in order to evaluate liver toxicity and a...

journal_title：Acta haematologica

authors： Marra R,Pagano L,De Stefano V,Leone G,Bizzi B

更新日期：1986-01-01 00:00:00

abstract：:Two unrelated patients with Bernard-Soulier syndrome and their relatives were studied. The patients demonstrated severe bleeding diathesis, the relatives were asymptomatic. The propositi showed the characteristic abnormalities of the syndrome: thrombocytopenia, a percentage of giant platelets higher than 65%, prolonge...

journal_title：Acta haematologica

authors： De Marco L,Fabris F,Casonato A,Fabris P,Dal Ben MG,Barbato A,Girolami A

更新日期：1986-01-01 00:00:00

abstract：:The fibrinolytic response to surgical trauma was studied longitudinally in 7 pigs by measuring the fibrinolytic activity in the blood and vein wall simultaneously. The results indicated a marked suppression in fibrinolytic activity in the blood which was closely correlated with the activity in the vein wall. This corr...

journal_title：Acta haematologica

authors： Wu AV,Mansfield AO

更新日期：1980-01-01 00:00:00

abstract：:We studied 14 adult patients presenting with fever and cytopenia of the peripheral blood and histiocytic hyperplasia with hemophagocytosis (HHH) in the bone marrow regarding an association of cytomegalovirus (CMV) and Epstein-Barr virus (EBV) by using in situ hybridization (ISH) and also evaluated the clinical and lab...

journal_title：Acta haematologica

authors： Han K,Kim Y,Kahng J,Lee J,Moon Y,Kang C,Shim S

更新日期：1996-01-01 00:00:00

abstract：:At our hospital, 47 out of 184 consecutive splenectomies performed over 7 recent years were carried out on patients afflicted with various hematologic diseases. The results of these 47 splenectomies were the subject of a careful retrospective analysis. The majority of the splenectomies (81%) were therapeutic. Cytopeni...

journal_title：Acta haematologica

authors： Dotevall A,Kutti J,Wadenvik H,Westin J,Angerås U,Darle N

更新日期：1987-01-01 00:00:00

abstract：:A 77-year-old woman presented to the outpatient hematology clinic in August 2001 with leukocytosis, recurrent bacterial infections, sweating and weight loss. Bone marrow biopsy showed 80% infiltration with lymphoid cells having a prolymphocytic morphology. Flow-cytometric immunophenotype analysis showed that over 80% ...

journal_title：Acta haematologica

authors： Zver S,Kokalj Vokac N,Zagradisnik B,Erjavec A,Zagorac A,Zupan IP,Cernelc P

更新日期：2004-01-01 00:00:00

abstract：:We studied neutrophil chemotaxis and surface membrane glycoproteins in 12 patients suffering from myeloid disorders with abnormal karyotype using in vitro techniques in all 12. Chromosome studies were also carried out virtually simultaneously. We chose to study only patients showing a deficit of chemotaxis (p less tha...

journal_title：Acta haematologica

authors： Ricevuti G,Mazzone A,Notario A

更新日期：1989-01-01 00:00:00

abstract：:It has been found possible to test ferritin concentrations in the reticulum and hemopoietic cells from human bone marrow by an immunoradiometric assay. Ferritin concentration in healthy test persons amounts to 0.92 +/- 0.38 ng/microgram protein in the reticulum and 0.084 +/- 0.031 ng/microgram protein in hemopoietic c...

journal_title：Acta haematologica

authors： Oertel J,Stephan M,Kastner M

更新日期：1982-01-01 00:00:00

abstract：:Hypercalcemia in malignancies is a frequent complication, mostly affecting patients with solid tumors or multiple myeloma. Calcium elevation is induced by direct bone infiltration of a tumor mass or through calcium liberation from the skeleton by a humoral mediator. The latter mechanism is referred to as humoral hyper...

journal_title：Acta haematologica

authors： Kampfenkel T,Baraniskin A,Teschendorf C,Schmiegel W,Massenkeil G

更新日期：2010-01-01 00:00:00

abstract：:Gene therapy targeting hematopoietic cells has arrived at a new stage of potency. While the potential for curing inherited disorders of the immune system has been demonstrated in clinical trials, we were also confronted with the first serious adverse events related to random insertion of foreign DNA into cellular chro...

journal_title：Acta haematologica

authors： Baum C,von Kalle C

更新日期：2003-01-01 00:00:00

abstract：:We have studied the amount and intracellular distribution of erythroblastic alkaline and acid phosphatase, nonspecific esterase, and N-acetyl-beta-glucosaminidase in 50 patients with acquired dyserythropoiesis. 19 morphologically normal bone marrow smears served as controls. Alkaline phosphatase was found in all contr...

journal_title：Acta haematologica

authors： Woessner S,Lafuente R,Florensa L,Sans-Sabrafen J

更新日期：1984-01-01 00:00:00

abstract：:The plasminogen activator content of a vein wall has been measured by estimating the radio-activity released from a 125I-tagged fibrin clot by incubating that clot with a known weight of the vein wall. This method could be used in the investigation of the fibrinolytic system of the body in its normal distribution and ...

journal_title：Acta haematologica

authors： Johnson RH,Mansfield AO

更新日期：1978-01-01 00:00:00

abstract：:Bone marrow fragments from 10 patients with a megaloblastic anaemia due to vitamin B12 or folate deficiency were studied by electron microscopy and electron microscope autoradiography. A proportion of the erythroblasts showed ultrastructural abnormalities. Some of the cells containing autophagic vacuoles, large sidero...

journal_title：Acta haematologica

authors： Wickramasinghe SN,Bush V

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:Adherence to tyrosine kinase inhibitor treatment is a significant factor in the achievement of a good clinical response in chronic myeloid leukemia (CML). The aim of this retrospective study is to investigate 1- and 2-year medication adherence to imatinib treatment, linking adherence rates with the clinical o...

journal_title：Acta haematologica

authors： Santoleri F,Lasala R,Ranucci E,La Barba G,Di Lorenzo R,Vetrò A,Di Bartolomeo P,Costantini A

更新日期：2016-01-01 00:00:00

abstract：:Chronic graft-versus-host disease (GVHD) is a severe complication of allogeneic stem cell transplantation, with a substantial impact on the quality of life and survival, still lacking with regard to an optimal therapeutic strategy. Corticosteroids are considered the standard of care for first-line treatment of chronic...

journal_title：Acta haematologica

authors： Michael M,Shimoni A,Nagler A

更新日期：2013-01-01 00:00:00

abstract：:The increased incidence of parallel tubular structures in lymphocytes of patients with Hodgkin's disease was investigated for a correlation with either impairment of cellular immunity (measured by DNCB-skin test and PHA-induced lymphocyte stimulation in vitro) or an increase of antibodies against cytomegalovirus or Ep...

journal_title：Acta haematologica

authors： Halie MR,Langenhuysen MM,de Gast GC,Nieweg HO

更新日期：1975-01-01 00:00:00

abstract：:B6D2F1 female mice were intravenously administered 0.4 mg of glucan. 1, 5, 11, and 17 days later, the total nucleated cellularity (TNC) and the numbers of pluripotent hemopoietic stem cells (CFU-s), granulocyte-macrophage progenitor cells (GM-CFC), and erythroid colony-forming (CFU-e) and burst-forming (BFU-e) cells w...

journal_title：Acta haematologica

authors： Patchen ML,MacVittie TJ

更新日期：1983-01-01 00:00:00

abstract：:The case history of a 71-year-old woman with three episodes of a microangiopathic hemolytic anemia over a 22-year span is detailed. During the last episode a possible response of her thrombotic thrombocytopenic purpura (TTP)-like syndrome to the administration of intravenous immunoglobulin is documented. In retrospect...

journal_title：Acta haematologica

authors： Staszewski H,Colbourn D,Donovan V,Ludman H

更新日期：1989-01-01 00:00:00

abstract：:It was confirmed that activation of the kallikrein-kinin enzyme system in cryoglobulinemia might be initiated by activation of factor XII to factor XIIa by cryoglobulin. It was also demonstrated that cryoglobulin or fibrin clots lost their ability to redissolve on warming to 37 degrees C, and consequently the lysis ti...

journal_title：Acta haematologica

authors： Kataoka K,Yamada S,Toki N

更新日期：1984-01-01 00:00:00

abstract：:Malaria parasites growing inside human erythrocytes differ from mammalian cells in their mode of acquisition of bioavailable iron and in their susceptibility to the antiproliferative action of iron chelators. We have assessed here three major properties associated with these phenomena: (a) the stage-dependent nature o...

journal_title：Acta haematologica

authors： Cabantchik ZI,Glickstein H,Golenser J,Loyevsky M,Tsafack A

更新日期：1996-01-01 00:00:00

abstract：:A 16-year-old Japanese woman with acute myelogenous leukemia (AML) and t(6;9) received peripheral blood stem cell transplantation (PBSCT). Although chromosomal studies just prior to and following PBSCT showed a normal karyotype, reverse transcription-polymerase chain reaction (RT-PCR) detected the mRNA derived from th...

journal_title：Acta haematologica

authors： Nakano H,Shimamoto Y,Suga K,Kobayashi M

更新日期：1995-01-01 00:00:00

abstract：:G-banded cytogenetic studies of 3 male patients in the terminal phase of chronic myeloid leukemia showed the following abnormalities: in the first case, the presence of a medullar cell line with 51 chromosomes and 3 Ph1; in the second case, a clone with 65 chromosomes and 4 Ph1, and in the third patient a clone with 5...

journal_title：Acta haematologica

authors： Cabrol C,Peytremann R,Maurice PA

更新日期：1982-01-01 00:00:00

abstract：:Acute myelogenous leukemia (AML) of the inbred Wistar/Furth (W/Fu) rat is pathophysiologically similar to human AML. Subcutaneous transplantation of 1.0 X 10(6) cells of a clonal tissue culture line of W/Fu AML into 6- to 8-week-old rats produced local myeloblastomas in 8--10 days which progressed to infiltration of r...

journal_title：Acta haematologica

authors： Greenberger JS,Bocaccino CA,Szot SJ,Moloney WC

更新日期：1977-03-01 00:00:00

abstract：:Agranulocytosis is a rare side effect of phenytoin treatment. We describe the case of an elderly man who developed agranulocytosis 2 weeks following initiation of phenytoin treatment, on no cytotoxic drugs or any other medications except decadron. The white blood cell count was 300/mm3 with absent granulocytes. The li...

journal_title：Acta haematologica

authors： Sharafuddin MJ,Spanheimer RG,McClune GL

更新日期：1991-01-01 00:00:00