A new method for the detection of the plasminogen activator content of vein walls.

abstract：:In a group of 56 patients with acute leukaemia, the relation between leukaemic cell motility and peripheral leukaemic cell count, degree of organomegaly, maturation and FAB classification was investigated. Cell motility was studied by means of directly observed motility and scoring of handmirror cells and anti-HLA-cap...

journal_title：Acta haematologica

authors： van der Weide M,Imandt LM,Langenhuijsen MM

更新日期：1988-01-01 00:00:00

abstract：:Systematic reviews and meta-analyses have made a major contribution to the evidence-based management of infections in cancer patients. We review the contribution of systematic reviews with regard to antibiotic, antifungal, antiviral and Pneumocystis pneumonia prophylaxis; antibiotic and antifungal treatment of febrile...

journal_title：Acta haematologica

authors： Paul M,Gafter-Gvili A,Goldberg E,Yahav D

更新日期：2011-01-01 00:00:00

abstract：:We report on a patient with chronic myeloid leukemia (CML) with a rapidly growing left cervical tumor 5 months after the initial diagnosis of CML. This tumor was diagnosed as a very early manifestation of extramedullary myeloblastoma by a minimally invasive method. A fine needle aspirate (26-gauge needle) was obtained...

journal_title：Acta haematologica

authors： Karthaus M,Meran JG,Wilkens L,Soudah B,Diedrich H,Krauter J,Ganser A,Heil G

更新日期：1998-01-01 00:00:00

abstract：:Treatment options are limited for patients with advanced forms of myeloproliferative neoplasms (MPN) including blast-phase disease (MPN-BP). Decitabine has frequently been deployed but its efficacy and safety profile are not well described in this population. We retrospectively reviewed 42 patients treated with decita...

journal_title：Acta haematologica

authors： Zhou S,Tremblay D,Hoffman R,Kremyanskaya M,Najfeld V,Li L,Moshier E,Mascarenhas J

更新日期：2021-01-01 00:00:00

abstract：:Among the 193 patients (82 female, 111 male) treated primarily for Hodgkin's disease at our clinic between 1990 and 2001 and followed up until 2003, 42 (22%) had mediastinal bulky tumours (MBTs) by the Cotswolds criteria. The rate of MBT diagnosis was significantly greater in the early stage of the disease, these pati...

journal_title：Acta haematologica

authors： Keresztes K,Lengyel Z,Devenyi K,Vadasz G,Miltenyi Z,Illes A

更新日期：2004-01-01 00:00:00

abstract：:Acute myelogenous leukemia (AML) of the inbred Wistar/Furth (W/Fu) rat is pathophysiologically similar to human AML. Subcutaneous transplantation of 1.0 X 10(6) cells of a clonal tissue culture line of W/Fu AML into 6- to 8-week-old rats produced local myeloblastomas in 8--10 days which progressed to infiltration of r...

journal_title：Acta haematologica

authors： Greenberger JS,Bocaccino CA,Szot SJ,Moloney WC

更新日期：1977-03-01 00:00:00

abstract：:Low-dose cytosine arabinoside (ARA-C) induced complete remissions in 6 of 10 patients with acute non-lymphocytic leukaemia (ANLL) who were either refractory to combination chemotherapy with anthracyclines and conventional doses of ARA-C, or were in relapse. Three patients relapsed after 4, 19, and 20 months, whereas 3...

journal_title：Acta haematologica

authors： Krogh Jensen M,Stentoft J

更新日期：1986-01-01 00:00:00

abstract：:Fetal liver transplantation was attempted in 7 patients with aplastic anemia. 4 of these patients showed a partial response as evidenced by decrease in blood transfusion requirements and increase in the peripheral blood counts and hematopoietic cells in the bone marrow. Bone marrow culture studies revealed evidence of...

journal_title：Acta haematologica

authors： Kansal V,Sood SK,Batra AK,Adhar G,Malviya AK,Kucheria K,Balakrishnan K

更新日期：1979-01-01 00:00:00

abstract：:Agranulocytosis is a rare side effect of phenytoin treatment. We describe the case of an elderly man who developed agranulocytosis 2 weeks following initiation of phenytoin treatment, on no cytotoxic drugs or any other medications except decadron. The white blood cell count was 300/mm3 with absent granulocytes. The li...

journal_title：Acta haematologica

authors： Sharafuddin MJ,Spanheimer RG,McClune GL

更新日期：1991-01-01 00:00:00

abstract：:A case of isolated lambda-light chain proteinemia and proteinuria is reported. During a 42-month follow-up, no sign of myelomatosis or amyloidosis developed and Bence Jones proteinuria remained nearly of the same magnitude. This case of apparently idiopathic Bence Jones gammopathy, the first lambda-type so far reporte...

journal_title：Acta haematologica

authors： Paladini G,Sala PG,Santini PA

更新日期：1980-01-01 00:00:00

abstract：:Haemoglobin synthesis was studied in bone marrow erythroblasts and in reticulocytes of 4 children with beta O-thalassaemia major and of 7 children with beta +-thalassaemia major. In patients with beta O-thalassaemia the gamma/a ratio was found to be lower in bone marrow than in peripheral blood. On the contrary, in pa...

journal_title：Acta haematologica

authors： Musumeci S,Schilirò G,Romeo MA,Pizzarelli G,Fischer A,Russo G

更新日期：1981-01-01 00:00:00

abstract：:Bone marrow samples of 28 individuals with clinically benign and of 41 patients with malignant monoclonal gammopathy were analyzed for the total number of lymphoplasmocellular elements containing cytoplasmic immunoglobulins and for the monoclonal fraction of these cells. Monoclonal immunoglobulin components were deter...

journal_title：Acta haematologica

authors： Morell A,Maurer W,Skvaril F,Barandun S

更新日期：1978-01-01 00:00:00

abstract：:A case of Philadelphia-positive (Ph) acute lymphoblastic leukaemia (ALL) in a 40-year-old male is presented. At diagnosis, 80% of bone marrow cells were Ph. Remission with normal blood counts was achieved but the marrow became hypercellular, indicating conversion to chronic granulocytic leukaemia (GCL). The Ph clone p...

journal_title：Acta haematologica

authors： O'Brien DV,Craig JM,Secker-Walker LM,Boughton BJ

更新日期：1993-01-01 00:00:00

abstract：:The objective of this study was to assess the pharmacokinetics of rhG-CSF after a single intraperitoneal injection 2 h post-TBI in B6D2F1 lethally irradiated mice and to analyze the effect of rhG-CSF on the endogenous response of interleukin-3 (IL-3), interleukin-6 (IL-6) and granulocyte-macrophage colony-stimulating ...

journal_title：Acta haematologica

authors： Kádár E,Sureda A,Mangues MA,Inglés-Esteve J,Valls A,García J

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:This study aimed to compare the curative effects of the combination therapy of all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO, As₂O₃) with ATRA monotherapy on newly diagnosed acute promyelocytic leukemia (APL). METHODS:The studies were retrieved from PubMed, EMBASE, Cochrane Library, ChinaInfo and...

journal_title：Acta haematologica

authors： Ma H,Yang J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:The aim of this work was to investigate the efficacy and predictive factors of CLAG treatment in refractory or relapsed (R/R) acute myeloid leukemia (AML) patients. METHODS:Sixty-seven R/R AML patients were enrolled in this prospective cohort study and treated by a CLAG regimen: 5 mg/m2/day cladribine ...

journal_title：Acta haematologica

authors： Wang L,Xu J,Tian X,Lv T,Yuan G

更新日期：2019-01-01 00:00:00

abstract：:Janus kinases are critical components of signaling pathways that regulate hematopoiesis. Mutations of the non-receptor tyrosine kinase JAK2 are found in many BCR-ABL-negative myeloproliferative neoplasms. Preclinical results support that JAK2 inhibitors could show efficacy in treating chronic myeloproliferative neopla...

journal_title：Acta haematologica

authors： Ringel F,Kaeda J,Schwarz M,Oberender C,Grille P,Dörken B,Marque F,Manley PW,Radimerski T,le Coutre P

更新日期：2014-01-01 00:00:00

abstract：:This paper reports the bone marrow histological picture in 7 patients with hairy cell leukemia treated with recombinant interferon. Bone marrow biopsies were performed at diagnosis, after 1, 3 and 7 months from the beginning of treatment and at 12 months at treatment suspension. The main modifications observed were a ...

journal_title：Acta haematologica

authors： Lambertenghi-Deliliers G,Benazzi E,Cortelezzi A,Polli EE

更新日期：1987-01-01 00:00:00

abstract：:We studied neutrophil chemotaxis and surface membrane glycoproteins in 12 patients suffering from myeloid disorders with abnormal karyotype using in vitro techniques in all 12. Chromosome studies were also carried out virtually simultaneously. We chose to study only patients showing a deficit of chemotaxis (p less tha...

journal_title：Acta haematologica

authors： Ricevuti G,Mazzone A,Notario A

更新日期：1989-01-01 00:00:00

abstract：:Platelet to leukocyte adhesion phenomena (PLAP) and the phagocytosis of platelets by neutrophils from the EDTA anticoagulated blood samples are described. PLAP was transferable to a normal blood specimen by patient's plasma or serum with or without complement. Further studies revealed in vitro evidence of hereditary p...

journal_title：Acta haematologica

authors： Yoo D,Weems H,Lessin LS

更新日期：1982-01-01 00:00:00

abstract：:We report a patient with lung cancer who developed CD56-positive acute lymphoblastic leukemia. He was referred to our hospital for thrombocytopenia. Atypical cells were found in the blood and the bone marrow. These cells were immunophenotypically positive for CD3epsilon, CD56, and terminal deoxynucleotidyl transferase...

journal_title：Acta haematologica

authors： Matano S,Terahata S,Nakamura S,Kobayashi K,Sugimoto T

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:Reticulated platelets circulating in the blood reflect megakaryopoietic activity and platelet turnover and can be automatically and low-invasively measured as the immature platelet fraction (IPF) using a Sysmex XN hematocytometer. The present study retrospectively investigated whether or not the IPF can pred...

journal_title：Acta haematologica

authors： Takami A,Mizuno S,Nakamura A,Kanasugi J,Yamamoto H,Vu Quang L,Nakagami Y,Nakano Y,Yamada S,Matsumura S,Takasugi S,Uchino K,Horio T,Murakami S,Oohigashi Y,Nakayama T,Tani H,Enomoto M,Hanamura I

更新日期：2020-09-17 00:00:00

abstract：:This report describes a case of hairy cell leukemia (HCL) occurring with autoimmune chronic active hepatitis (CAH). A 74-year-old woman presented with typical clinical and histologic features of HCL for which splenectomy was performed. 2 years later she developed abnormal liver function tests due to auto-immune CAH. T...

journal_title：Acta haematologica

authors： Begley CG,Mackay IR,Bhathal PS

更新日期：1985-01-01 00:00:00

abstract：:Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is a rare lymphoproliferative disorder characterized by diffuse lymphadenopathy, fever, hepatosplenomegaly, hemolytic anemia, and polyclonal hypergammaglobulinemia. Morphologically, the involved lymph nodes demonstrate complete effacement of the normal arch...

journal_title：Acta haematologica

authors： Sallah S,Gagnon GA

更新日期：1998-01-01 00:00:00

abstract：:In 34 patients with chronic lymphatic leukaemia (CLL) the lymphocytes have been separated and sized using a C1000 Channelyzer. The modal volume and the volume range of the populations have been obtained and related to clinical stage and mouse red blood cell (MRBC) rosetting capacity. Over 1 year's observation with sev...

journal_title：Acta haematologica

authors： Wastell HJ,Proctor SJ

更新日期：1983-01-01 00:00:00

abstract：:Factor X inhibitors are rare. The few cases documented in the literature have occurred after viral prodromes, in association with cancer, or after exposure to antibiotics. Acquired factor X deficiencies are also rare and their etiology is largely unknown. We report a new case of a factor X inhibitor and review prior c...

journal_title：Acta haematologica

authors： Gollard R,Rahman S,Ratnasabapathy R

更新日期：2013-01-01 00:00:00

abstract：:Immunoglobulin light chain amyloidosis (AL amyloidosis) is a rare, life-threatening disease characterized by the deposition of misfolded proteins in vital organs such as the heart, the lungs, the kidneys, the peripheral nervous system, and the gastrointestinal tract. This causes a direct toxic effect, eventually leadi...

journal_title：Acta haematologica

authors： Van Doren L,Lentzsch S

更新日期：2020-01-01 00:00:00

abstract：:The effect of total-body cold exposure on plasma concentrations of von Willebrand factor (vWF), endothelin-1 (ET) and thrombomodulin (TM), all of which are considered to be generated from the endothelium, was studied in systemic lupus erythematosus (SLE) patients with and without Raynaud's phenomenon. The plasma level...

journal_title：Acta haematologica

authors： Matsuda J,Tsukamoto M,Gohchi K,Saitoh N,Miyajima Y,Kazama M

更新日期：1992-01-01 00:00:00

abstract：:Inferferon alfa-2b (IFN) plays a major role in the current management of previously untreated patients with chronic myelogenous leukemia (CML) as well as patients with CML who have relapsed after bone marrow transplantation. Hydroxyurea (HU) is the best conventional drug for treatment of CML in the chronic phase. Ten ...

journal_title：Acta haematologica

authors： Bourantas KL,Syrou M,Tsiara S,Danella M,Konstantinides P

更新日期：1996-01-01 00:00:00

abstract：:One of the major determinants of erythrocyte survival is membrane deformability, and an important intrinsic parameter of membrane deformability is the shear elastic modulus (mu) with higher mu values corresponding to increased membrane rigidity. Using a micropipette technique, we determined the shear elastic modulus o...

journal_title：Acta haematologica

authors： Athanassiou G,Symeonidis A,Kourakli A,Missirlis YF,Zoumbos NC

更新日期：1992-01-01 00:00:00